Carbonic anhydrase 9 expression increases with vascular endothelial growth factor-targeted therapy and is predictive of outcome in metastatic clear cell renal cancer

European urology

Volumn 66, Issue 5, 2014, Pages 956-963

  Stewart, Grant D ^a   O'Mahony, Fiach C ^a   Laird, Alexander ^a   Rashid, Sukaina ^b   Martin, Sarah A ^a   Eory, Lel ^a   Lubbock, Alexander L R ^a   Nanda, Jyoti ^b   O'Donnell, Marie ^a   Mackay, Alan ^a   Mullen, Peter ^a   McNeill, S Alan ^a   Riddick, Antony C P ^a   Aitchison, Michael ^a   Berney, Daniel ^b   Bex, Axel ^b   Overton, Ian M ^b   Harrison, David J ^a   Powles, Thomas ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

Biomarker; CA9; Renal cancer; VEGF TKI

Indexed keywords

ANTINEOPLASTIC AGENT; CA9 PROTEIN, HUMAN; CARBONATE DEHYDRATASE; INDOLE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRROLE DERIVATIVE; SUNITINIB; TUMOR ANTIGEN; TUMOR MARKER; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

AGED; ANTAGONISTS AND INHIBITORS; CARCINOMA, RENAL CELL; CLINICAL TRIAL; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HUMAN; KIDNEY NEOPLASMS; MALE; METABOLISM; MIDDLE AGED; MOLECULARLY TARGETED THERAPY; PATHOLOGY; PHASE 2 CLINICAL TRIAL; PILOT STUDY; PREDICTIVE VALUE; PROCEDURES; PROTEOMICS; REPRODUCIBILITY; RNA INTERFERENCE; SECONDARY; TIME; TISSUE MICROARRAY; TREATMENT OUTCOME; TUMOR CELL LINE; UPREGULATION;

AGED; ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; BIOMARKERS, TUMOR; CARBONIC ANHYDRASES; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; COMPARATIVE GENOMIC HYBRIDIZATION; HUMANS; INDOLES; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; MOLECULAR TARGETED THERAPY; PILOT PROJECTS; PREDICTIVE VALUE OF TESTS; PROTEIN KINASE INHIBITORS; PROTEOMICS; PYRROLES; REPRODUCIBILITY OF RESULTS; RNA INTERFERENCE; TIME FACTORS; TISSUE ARRAY ANALYSIS; TRANSFECTION; TREATMENT OUTCOME; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84965085261     PISSN: None     EISSN: 18737560     Source Type: Journal    
DOI: 10.1016/j.eururo.2014.04.007     Document Type: Article

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