Computational investigation of the selectivity of salen and tetrahydrosalen compounds towards the tumor-associated hCA XII isozyme

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 30, Issue 1, 2015, Pages 114-118

  Akdemir, Atilla ^a   De Monte, Celeste ^b   Carradori, Simone ^b   Supuran, Claudiu T ^c  

^a BEZMIALEM VAKIF UNIVERSITY   (Turkey)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Carbonic anhydrase inhibitor; Docking; Salen; Tetrahydrosalen

Indexed keywords

CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE XII; ISOENZYME; SALEN COMPOUND; TETRAHYDROSALEN COMPOUND; UNCLASSIFIED DRUG; ZINC; CA9 PROTEIN, HUMAN; CARBONATE DEHYDRATASE; DISALICYLALDEHYDE ETHYLENEDIAMINE; ETHYLENEDIAMINE DERIVATIVE; PROTEIN BINDING; RECOMBINANT PROTEIN; TUMOR ANTIGEN; TUMOR PROTEIN; WATER;

ARTICLE; ENZYME INHIBITION ASSAY; IC50; MOLECULAR DOCKING; MOLECULAR MODEL; PRIORITY JOURNAL; BINDING SITE; CHEMISTRY; HUMAN; SYNTHESIS;

ANTIGENS, NEOPLASM; BINDING SITES; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; ETHYLENEDIAMINES; HUMANS; MOLECULAR DOCKING SIMULATION; NEOPLASM PROTEINS; PROTEIN BINDING; RECOMBINANT PROTEINS; WATER; ZINC;

EID: 84904303895     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2014.892936     Document Type: Article

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