Metallocene-based inhibitors of cancer-associated carbonic anhydrase enzymes IX and XII

Journal of Medicinal Chemistry

Volumn 55, Issue 11, 2012, Pages 5506-5517

  Salmon, Adam J ^a   Williams, Michael L ^a   Wu, Quoc K ^b   Morizzi, Julia ^b   Gregg, Daniel ^b   Charman, Susan A ^b   Vullo, Daniela ^c   Supuran, Claudiu T ^c   Poulsen, Sally Ann ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 SULFAMOYLPHENYL) 1H 1,2,3 TRIAZOL 4 YL]ETHYL FERROCENYL 1 CARBOXYLATE; 2 [1 (4 SULFAMOYLPHENYL) 1H 1,2,3 TRIAZOL 4 YL]ETHYL FERROCENYL 1 CARBOXYLATE; 3 (4 FERROCENYL 1H 1,2,3 TRIAZOL 1 YL)BENZENESULFONAMIDE; 3 (4 PHENYL 1H 1,2,3 TRIAZOL 1 YL)BENZENESULFONAMIDE; 3 (4 RUTHENOCENYL 1H 1,2,3 TRIAZOL 1 YL)BENZENESULFONAMIDE; 3 (5 FERROCENYL 1H 1,2,3 TRIAZOL 1 YL)BENZENESULFONAMIDE; 3 (5 RUTHENOCENYL 1H 1,2,3 TRIAZOL 1 YL)BENZENESULFONAMIDE; 3 [1 (3 SULFAMOYLPHENYL) 1H 1,2,3 TRIAZOL 4 YL]PROPYL FERROCENYL 1 CARBOXYLATE; 3 [1 (4 SULFAMOYLPHENYL) 1H 1,2,3 TRIAZOL 4 YL]PROPYL FERROCENYL 1 CARBOXYLATE; 4 (3 FERROCENYLUREIDO)BENZENESULFONAMIDE; 4 (4 PHENYL 1H 1,2,3 TRIAZOL 1 YL)BENZENESULFONAMIDE; 4 (5 PHENYL 1H 1,2,3 TRIAZOL 1 YL)BENZENESULFONAMIDE; [1 (3 SULFAMOYLPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHYL FERROCENYL 1 CARBOXYLATE; [1 (4 SULFAMOYLPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHYL FERROCENYL 1 CARBOXYLATE; AMIDE; ANTINEOPLASTIC AGENT; BENZENESULFONAMIDE DERIVATIVE; CARBONATE DEHYDRATASE I INHIBITOR; CARBONATE DEHYDRATASE II INHIBITOR; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IX INHIBITOR; CARBONATE DEHYDRATASE XII INHIBITOR; FERROCENE DERIVATIVE; METALLOCENE DERIVATIVE; N (3 SULFAMOYLPHENYL)FERROCENYL 1 CARBOXAMIDE; N (4 SULFAMOYLPHENYL)FERROCENYL 1 CARBOXAMIDE; N [1 (3 SULFAMOYLPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHYL FERROCENYL 1 CARBOXYLATE; N [1 (4 SULFAMOYLPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHYL FERROCENYL 1 CARBOXYLATE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG PENETRATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROPHOBICITY; IN VITRO STUDY; LIPOPHILICITY;

ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; CACO-2 CELLS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; COORDINATION COMPLEXES; CYCLOPENTANES; FERROUS COMPOUNDS; HUMANS; MICROSOMES, LIVER; PERMEABILITY; RUTHENIUM; SOLUBILITY; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84862296302     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300427m     Document Type: Article

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