-
1
-
-
84901780101
-
Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca2+ sensitivity
-
Acuna C, Guo Q, Burre J, Sharma M, Sun J, Sudhof TC. 2014. Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca2+ sensitivity. Neuron 82: 1088-100
-
(2014)
Neuron
, vol.82
, pp. 1088-1100
-
-
Acuna, C.1
Guo, Q.2
Burre, J.3
Sharma, M.4
Sun, J.5
Sudhof, T.C.6
-
2
-
-
84862534274
-
Energetics of stalk intermediates in membrane fusion are controlled by lipid composition
-
Aeffner S, Reusch T, Weinhausen B, Salditt T. 2012. Energetics of stalk intermediates in membrane fusion are controlled by lipid composition. PNAS 109: E1609-18
-
(2012)
PNAS
, vol.109
, pp. E1609-E1618
-
-
Aeffner, S.1
Reusch, T.2
Weinhausen, B.3
Salditt, T.4
-
3
-
-
33644804207
-
Close membrane-membrane proximity induced by Ca2+-dependent multivalent binding of synaptotagmin-1 to phospholipids
-
Arac D, Chen X, Khant HA, Ubach J, Ludtke SJ, et al. 2006. Close membrane-membrane proximity induced by Ca2+-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat. Struct. Mol. Biol. 13: 209-17
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 209-217
-
-
Arac, D.1
Chen, X.2
Khant, H.A.3
Ubach, J.4
Ludtke, S.J.5
-
4
-
-
84885441885
-
Titration of Syntaxin1 in mammalian synapses reveals multiple roles in vesicle docking, priming, and release probability
-
Arancillo M, Min SW, Gerber S, Munster-Wandowski A, Wu YJ, et al. 2013. Titration of Syntaxin1 in mammalian synapses reveals multiple roles in vesicle docking, priming, and release probability. J. Neurosci. 33: 16698-714
-
(2013)
J. Neurosci.
, vol.33
, pp. 16698-16714
-
-
Arancillo, M.1
Min, S.W.2
Gerber, S.3
Munster-Wandowski, A.4
Wu, Y.J.5
-
5
-
-
0033352861
-
Drosophila UNC-13 is essential for synaptic transmission
-
Aravamudan B, Fergestad T, DavisWS, Rodesch CK, Broadie K. 1999. Drosophila UNC-13 is essential for synaptic transmission. Nat. Neurosci. 2: 965-71
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 965-971
-
-
Aravamudan, B.1
Fergestad, T.2
Davis, W.S.3
Rodesch, C.K.4
Broadie, K.5
-
6
-
-
84887001711
-
Synaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter release
-
Bacaj T, Wu D, Yang X, Morishita W, Zhou P, et al. 2013. Synaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter release. Neuron 80: 947-59
-
(2013)
Neuron
, vol.80
, pp. 947-959
-
-
Bacaj, T.1
Wu, D.2
Yang, X.3
Morishita, W.4
Zhou, P.5
-
7
-
-
0029808089
-
N-Ethylmaleimide-sensitive factor acts at a prefusion ATP-dependent step in Ca2+-activated exocytosis
-
Banerjee A, Barry VA, DasGupta BR, Martin TF. 1996. N-Ethylmaleimide-sensitive factor acts at a prefusion ATP-dependent step in Ca2+-activated exocytosis. J. Biol. Chem. 271: 20223-26
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20223-20226
-
-
Banerjee, A.1
Barry, V.A.2
Dasgupta, B.R.3
Martin, T.F.4
-
8
-
-
33645014145
-
A minimal domain responsible for Munc13 activity
-
Basu J, Shen N, Dulubova I, Lu J, Guan R, et al. 2005. A minimal domain responsible for Munc13 activity. Nat. Struct. Mol. Biol. 12: 1017-18
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 1017-1018
-
-
Basu, J.1
Shen, N.2
Dulubova, I.3
Lu, J.4
Guan, R.5
-
9
-
-
33745029549
-
Ca2+-synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusion
-
Bhalla A, Chicka MC, Tucker WC, Chapman ER. 2006. Ca2+-synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusion. Nat. Struct. Mol. Biol. 13: 323-30
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 323-330
-
-
Bhalla, A.1
Chicka, M.C.2
Tucker, W.C.3
Chapman, E.R.4
-
10
-
-
84898619506
-
SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion
-
Bharat TA, Malsam J, Hagen WJ, Scheutzow A, Sollner TH, Briggs JA. 2014. SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion. EMBO Rep. 15: 308-14
-
(2014)
EMBO Rep.
, vol.15
, pp. 308-314
-
-
Bharat, T.A.1
Malsam, J.2
Hagen, W.J.3
Scheutzow, A.4
Sollner, T.H.5
Briggs, J.A.6
-
11
-
-
84861922902
-
Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion
-
Boswell KL, James DJ, Esquibel JM, Bruinsma S, Shirakawa R, et al. 2012. Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion. J. Cell Biol. 197: 301-12
-
(2012)
J. Cell Biol.
, vol.197
, pp. 301-312
-
-
Boswell, K.L.1
James, D.J.2
Esquibel, J.M.3
Bruinsma, S.4
Shirakawa, R.5
-
12
-
-
0037112932
-
Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p
-
Bracher A, Weissenhorn W. 2002. Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p. EMBO J. 21: 6114-24
-
(2002)
EMBO J.
, vol.21
, pp. 6114-6124
-
-
Bracher, A.1
Weissenhorn, W.2
-
14
-
-
41949130893
-
Munc18a controlsSNAREassembly through its interaction with the Syntaxin N-peptide
-
BurkhardtP, Hattendorf DA, Weis WI, Fasshauer D. 2008. Munc18a controlsSNAREassembly through its interaction with the Syntaxin N-peptide. EMBO J. 27: 923-33
-
(2008)
EMBO J.
, vol.27
, pp. 923-933
-
-
Burkhardt, P.1
Hattendorf, D.A.2
Weis, W.I.3
Fasshauer, D.4
-
15
-
-
80053083748
-
Primordial neurosecretory apparatus identified in the choanoflagellate
-
Burkhardt P, Stegmann CM, Cooper B, Kloepper TH, Imig C, et al. 2011. Primordial neurosecretory apparatus identified in the choanoflagellate. Monosiga brevicollis. PNAS 108: 15264-69
-
(2011)
Monosiga Brevicollis. PNAS
, vol.108
, pp. 15264-15269
-
-
Burkhardt, P.1
Stegmann, C.M.2
Cooper, B.3
Kloepper, T.H.4
Imig, C.5
-
16
-
-
34247623568
-
Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle
-
Cai H, Reinisch K, Ferro-Novick S. 2007. Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle. Dev. Cell 12: 671-82
-
(2007)
Dev. Cell
, vol.12
, pp. 671-682
-
-
Cai, H.1
Reinisch, K.2
Ferro-Novick, S.3
-
17
-
-
84872719528
-
Complexin activates exocytosis of distinct secretory vesicles controlled by different synaptotagmins
-
Cao P, Yang X, Sudhof TC. 2013. Complexin activates exocytosis of distinct secretory vesicles controlled by different synaptotagmins. J. Neurosci. 33: 1714-27
-
(2013)
J. Neurosci.
, vol.33
, pp. 1714-1727
-
-
Cao, P.1
Yang, X.2
Sudhof, T.C.3
-
18
-
-
0033606766
-
Sec1p binds to SNARE complexes and concentrates at sites of secretion
-
Carr CM, Grote E, Munson M, Hughson FM, Novick PJ. 1999. Sec1p binds to SNARE complexes and concentrates at sites of secretion. J. Cell Biol. 146: 333-44
-
(1999)
J. Cell Biol.
, vol.146
, pp. 333-344
-
-
Carr, C.M.1
Grote, E.2
Munson, M.3
Hughson, F.M.4
Novick, P.J.5
-
19
-
-
78049408948
-
At the junction of SNARE and SM protein function
-
Carr CM, Rizo J. 2010. At the junction of SNARE and SM protein function. Curr. Opin. Cell Biol. 22: 488-95
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 488-495
-
-
Carr, C.M.1
Rizo, J.2
-
20
-
-
59049093107
-
Effects of linker sequences on vesicle fusion mediated by lipidanchored DNA oligonucleotides
-
Chan YH, van LB, Boxer SG. 2009. Effects of linker sequences on vesicle fusion mediated by lipidanchored DNA oligonucleotides. PNAS 106: 979-84
-
(2009)
PNAS
, vol.106
, pp. 979-984
-
-
Chan, Y.H.1
Van, L.B.2
Boxer, S.G.3
-
21
-
-
46449093538
-
How Does synaptotagmin trigger neurotransmitter release?
-
Chapman ER. 2008. How Does synaptotagmin trigger neurotransmitter release? Annu. Rev. Biochem. 77: 615-41
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 615-641
-
-
Chapman, E.R.1
-
22
-
-
0032577067
-
Direct interaction of a Ca2+-binding loop of synaptotagmin with lipid bilayers
-
Chapman ER, Davis AF. 1998. Direct interaction of a Ca2+-binding loop of synaptotagmin with lipid bilayers. J. Biol. Chem. 273: 13995-4001
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13995-14001
-
-
Chapman, E.R.1
Davis, A.F.2
-
23
-
-
43649085762
-
NMR analysis of the closed conformation of Syntaxin-1
-
Chen X, Lu J, Dulubova I, Rizo J. 2008. NMR analysis of the closed conformation of Syntaxin-1. J. Biomol. NMR 41: 43-54
-
(2008)
J. Biomol. NMR
, vol.41
, pp. 43-54
-
-
Chen, X.1
Lu, J.2
Dulubova, I.3
Rizo, J.4
-
24
-
-
0037204076
-
Three-dimensional structure of the complexin/SNARE complex
-
Chen X, Tomchick DR, Kovrigin E, Arac D, Machius M, et al. 2002. Three-dimensional structure of the complexin/SNARE complex. Neuron 33: 397-409
-
(2002)
Neuron
, vol.33
, pp. 397-409
-
-
Chen, X.1
Tomchick, D.R.2
Kovrigin, E.3
Arac, D.4
Machius, M.5
-
26
-
-
49449095255
-
Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+
-
Chicka MC, Hui E, Liu H, Chapman ER. 2008. Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+. Nat. Struct. Mol. Biol. 15: 827-35
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 827-835
-
-
Chicka, M.C.1
Hui, E.2
Liu, H.3
Chapman, E.R.4
-
27
-
-
84904284070
-
Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo
-
Cho RW, Kummel D, Li F, Baguley SW, Coleman J, et al. 2014. Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo. PNAS 111: 10317-22
-
(2014)
PNAS
, vol.111
, pp. 10317-10322
-
-
Cho, R.W.1
Kummel, D.2
Li, F.3
Baguley, S.W.4
Coleman, J.5
-
28
-
-
77949264921
-
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex
-
Choi UB, Strop P, Vrljic M, Chu S, Brunger AT, Weninger KR. 2010. Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex. Nat. Struct. Mol. Biol. 17: 318-24
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 318-324
-
-
Choi, U.B.1
Strop, P.2
Vrljic, M.3
Chu, S.4
Brunger, A.T.5
Weninger, K.R.6
-
29
-
-
2942635759
-
The energetics of membrane fusion from binding, through hemifusion, pore formation, and pore enlargement
-
Cohen FS, Melikyan GB. 2004. The energetics of membrane fusion from binding, through hemifusion, pore formation, and pore enlargement. J. Membr. Biol. 199: 1-14
-
(2004)
J. Membr. Biol.
, vol.199
, pp. 1-14
-
-
Cohen, F.S.1
Melikyan, G.B.2
-
30
-
-
33847269603
-
A quaternary SNARE-synaptotagmin-Ca2+-phospholipid complex in neurotransmitter release
-
DaiH, ShenN, AracD, Rizo J. 2007. A quaternary SNARE-synaptotagmin-Ca2+-phospholipid complex in neurotransmitter release. J. Mol. Biol. 367: 848-63
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 848-863
-
-
Dai, H.1
Shen, N.2
Arac, D.3
Rizo, J.4
-
31
-
-
0027960576
-
Synergistic membrane interactions of the two C2 domains of synaptotagmin
-
Damer CK, Creutz CE. 1994. Synergistic membrane interactions of the two C2 domains of synaptotagmin. J. Biol. Chem. 269: 31115-23
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 31115-31123
-
-
Damer, C.K.1
Creutz, C.E.2
-
32
-
-
69449108209
-
Synaptotagmin-1 docks secretory vesicles to Syntaxin-1/SNAP-25 acceptor complexes
-
de Wit H, Walter AM, Milosevic I, Gulyas-Kovacs A, Riedel D, et al. 2009. Synaptotagmin-1 docks secretory vesicles to Syntaxin-1/SNAP-25 acceptor complexes. Cell 138: 935-46
-
(2009)
Cell
, vol.138
, pp. 935-946
-
-
De Wit, H.1
Walter, A.M.2
Milosevic, I.3
Gulyas-Kovacs, A.4
Riedel, D.5
-
33
-
-
33745800098
-
Structural determinants of Synaptobrevin 2 function in synaptic vesicle fusion
-
Deak F, Shin OH, Kavalali ET, Sudhof TC. 2006. Structural determinants of Synaptobrevin 2 function in synaptic vesicle fusion. J. Neurosci. 26: 6668-76
-
(2006)
J. Neurosci.
, vol.26
, pp. 6668-6676
-
-
Deak, F.1
Shin, O.H.2
Kavalali, E.T.3
Sudhof, T.C.4
-
34
-
-
64749107397
-
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming
-
Deak F, Xu Y, Chang WP, Dulubova I, Khvotchev M, et al. 2009. Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming. J. Cell Biol. 184: 751-64
-
(2009)
J. Cell Biol.
, vol.184
, pp. 751-764
-
-
Deak, F.1
Xu, Y.2
Chang, W.P.3
Dulubova, I.4
Khvotchev, M.5
-
35
-
-
84897516425
-
Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics
-
Dhara M, Yarzagaray A, Schwarz Y, Dutta S, Grabner C, et al. 2014. Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics. J. Cell Biol. 204: 1123-40
-
(2014)
J. Cell Biol.
, vol.204
, pp. 1123-1140
-
-
Dhara, M.1
Yarzagaray, A.2
Schwarz, Y.3
Dutta, S.4
Grabner, C.5
-
36
-
-
84886888321
-
Complexin-1 enhances the on-rate of vesicle docking via simultaneous SNARE and membrane interactions
-
Diao J, Cipriano DJ, Zhao M, Zhang Y, Shah S, et al. 2013. Complexin-1 enhances the on-rate of vesicle docking via simultaneous SNARE and membrane interactions. J. Am. Chem. Soc. 135: 15274-77
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 15274-15277
-
-
Diao, J.1
Cipriano, D.J.2
Zhao, M.3
Zhang, Y.4
Shah, S.5
-
37
-
-
84881514823
-
Synaptic proteins promote calciumtriggered fast transition from point contact to full fusion
-
Diao J, Grob P, Cipriano DJ, Kyoung M, Zhang Y, et al. 2012. Synaptic proteins promote calciumtriggered fast transition from point contact to full fusion. eLife 1: e00109
-
(2012)
ELife
, vol.1
, pp. e00109
-
-
Diao, J.1
Grob, P.2
Cipriano, D.J.3
Kyoung, M.4
Zhang, Y.5
-
38
-
-
28544432477
-
The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif
-
Dong G, Hutagalung AH, Fu C, Novick P, Reinisch KM. 2005. The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif. Nat. Struct. Mol. Biol. 12: 1094-100
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 1094-1100
-
-
Dong, G.1
Hutagalung, A.H.2
Fu, C.3
Novick, P.4
Reinisch, K.M.5
-
39
-
-
33847326814
-
Munc18-1 binds directly to the neuronal SNARE complex
-
Dulubova I, Khvotchev M, Liu S, Huryeva I, Sudhof TC, Rizo J. 2007. Munc18-1 binds directly to the neuronal SNARE complex. PNAS 104: 2697-702
-
(2007)
PNAS
, vol.104
, pp. 2697-2702
-
-
Dulubova, I.1
Khvotchev, M.2
Liu, S.3
Huryeva, I.4
Sudhof, T.C.5
Rizo, J.6
-
40
-
-
28844449520
-
AMunc13/RIM/Rab3 tripartite complex: From priming to plasticity?
-
Dulubova I, Lou X, Lu J, Huryeva I, Alam A, et al. 2005. AMunc13/RIM/Rab3 tripartite complex: from priming to plasticity? EMBO J. 24: 2839-50
-
(2005)
EMBO J
, vol.24
, pp. 2839-2850
-
-
Dulubova, I.1
Lou, X.2
Lu, J.3
Huryeva, I.4
Alam, A.5
-
41
-
-
0033575749
-
A conformational switch in Syntaxin during exocytosis: Role of munc18
-
Dulubova I, Sugita S, Hill S, Hosaka M, Fernandez I, et al. 1999. A conformational switch in Syntaxin during exocytosis: role of munc18. EMBO J. 18: 4372-82
-
(1999)
EMBO J.
, vol.18
, pp. 4372-4382
-
-
Dulubova, I.1
Sugita, S.2
Hill, S.3
Hosaka, M.4
Fernandez, I.5
-
42
-
-
0037422556
-
Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins
-
Dulubova I, Yamaguchi T, Arac D, Li H, Huryeva I, et al. 2003. Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins. PNAS 100: 32-37
-
(2003)
PNAS
, vol.100
, pp. 32-37
-
-
Dulubova, I.1
Yamaguchi, T.2
Arac, D.3
Li, H.4
Huryeva, I.5
-
43
-
-
0037099492
-
How Tlg2p/Syntaxin 16 'snares' Vps45
-
Dulubova I, Yamaguchi T, Gao Y, Min SW, Huryeva I, et al. 2002. How Tlg2p/Syntaxin 16 'snares' Vps45. EMBO J. 21: 3620-31
-
(2002)
EMBO J.
, vol.21
, pp. 3620-3631
-
-
Dulubova, I.1
Yamaguchi, T.2
Gao, Y.3
Min, S.W.4
Huryeva, I.5
-
44
-
-
0035126830
-
Vam3p structure reveals conserved and divergent properties of Syntaxins
-
Dulubova I, Yamaguchi T, Wang Y, Sudhof TC, Rizo J. 2001. Vam3p structure reveals conserved and divergent properties of Syntaxins. Nat. Struct. Biol. 8: 258-64
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 258-264
-
-
Dulubova, I.1
Yamaguchi, T.2
Wang, Y.3
Sudhof, T.C.4
Rizo, J.5
-
45
-
-
0032430423
-
Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q-and R-SNAREs
-
Fasshauer D, Sutton RB, Brunger AT, Jahn R. 1998. Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q-and R-SNAREs. PNAS 95: 15781-86
-
(1998)
PNAS
, vol.95
, pp. 15781-15786
-
-
Fasshauer, D.1
Sutton, R.B.2
Brunger, A.T.3
Jahn, R.4
-
46
-
-
0035924571
-
Three-dimensional structure of the synaptotagmin 1 C2B-domain: Synaptotagmin 1 as a phospholipid binding machine
-
Fernandez I, Arac D, Ubach J, Gerber SH, Shin O, et al. 2001. Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine. Neuron 32: 1057-69
-
(2001)
Neuron
, vol.32
, pp. 1057-1069
-
-
Fernandez, I.1
Arac, D.2
Ubach, J.3
Gerber, S.H.4
Shin, O.5
-
47
-
-
0032544441
-
Three-dimensional structure of an evolutionarily conserved N-terminal domain of Syntaxin 1A
-
Fernandez I, Ubach J, Dulubova I, Zhang X, Sudhof TC, Rizo J. 1998. Three-dimensional structure of an evolutionarily conserved N-terminal domain of Syntaxin 1A. Cell 94: 841-49
-
(1998)
Cell
, vol.94
, pp. 841-849
-
-
Fernandez, I.1
Ubach, J.2
Dulubova, I.3
Zhang, X.4
Sudhof, T.C.5
Rizo, J.6
-
48
-
-
0035282457
-
Synaptotagmin i functions as a calcium regulator of release probability
-
Fernandez-Chacon R, Konigstorfer A, Gerber SH, Garcia J, Matos MF, et al. 2001. Synaptotagmin I functions as a calcium regulator of release probability. Nature 410: 41-49
-
(2001)
Nature
, vol.410
, pp. 41-49
-
-
Fernandez-Chacon, R.1
Konigstorfer, A.2
Gerber, S.H.3
Garcia, J.4
Matos, M.F.5
-
49
-
-
70149094784
-
The N-terminal peptide of the Syntaxin Tlg2p modulates binding of its closed conformation toVps45p
-
Furgason ML, MacDonald C, Shanks SG, Ryder SP, Bryant NJ, Munson M. 2009. The N-terminal peptide of the Syntaxin Tlg2p modulates binding of its closed conformation toVps45p. PNAS106: 14303-8
-
(2009)
PNAS
, vol.106
, pp. 14303-14308
-
-
Furgason, M.L.1
Macdonald, C.2
Shanks, S.G.3
Ryder, S.P.4
Bryant, N.J.5
Munson, M.6
-
50
-
-
84901050663
-
Contact-induced clustering of Syntaxin andmunc18 docks secretory granules at the exocytosis site
-
Gandasi NR, Barg S. 2014. Contact-induced clustering of Syntaxin andmunc18 docks secretory granules at the exocytosis site. Nat. Commun. 5: 3914
-
(2014)
Nat. Commun.
, vol.5
, pp. 3914
-
-
Gandasi, N.R.1
Barg, S.2
-
51
-
-
84866132236
-
Single reconstituted neuronal SNARE complexes zipper in three distinct stages
-
Gao Y, Zorman S, Gundersen G, Xi Z, Ma L, et al. 2012. Single reconstituted neuronal SNARE complexes zipper in three distinct stages. Science 337: 1340-43
-
(2012)
Science
, vol.337
, pp. 1340-1343
-
-
Gao, Y.1
Zorman, S.2
Gundersen, G.3
Xi, Z.4
Ma, L.5
-
52
-
-
51749100843
-
Conformational switch of Syntaxin-1 controls synaptic vesicle fusion
-
Gerber SH, Rah JC, Min SW, Liu X, de Wit H, et al. 2008. Conformational switch of Syntaxin-1 controls synaptic vesicle fusion. Science 321: 1507-10
-
(2008)
Science
, vol.321
, pp. 1507-1510
-
-
Gerber, S.H.1
Rah, J.C.2
Min, S.W.3
Liu, X.4
De Wit, H.5
-
53
-
-
33746319639
-
A clamping mechanism involved in SNAREdependent exocytosis
-
Giraudo CG, Eng WS, Melia TJ, Rothman JE. 2006. A clamping mechanism involved in SNAREdependent exocytosis. Science 313: 676-80
-
(2006)
Science
, vol.313
, pp. 676-680
-
-
Giraudo, C.G.1
Eng, W.S.2
Melia, T.J.3
Rothman, J.E.4
-
54
-
-
58849105859
-
Alternative zippering as an on-off switch for SNARE-mediated fusion
-
Giraudo CG, Garcia-Diaz A, EngWS, Chen Y, HendricksonWA, et al. 2009. Alternative zippering as an on-off switch for SNARE-mediated fusion. Science 323: 512-16
-
(2009)
Science
, vol.323
, pp. 512-516
-
-
Giraudo, C.G.1
Garcia-Diaz, A.2
Eng . W, S.3
Chen, Y.4
Hendrickson, W.A.5
-
55
-
-
38749132516
-
A gain-of-function mutant of Munc18-1 stimulates secretory granule recruitment and exocytosis and reveals a direct interaction of Munc18-1 with Rab3
-
Graham ME, Handley MT, Barclay JW, Ciufo LF, Barrow SL, et al. 2008. A gain-of-function mutant of Munc18-1 stimulates secretory granule recruitment and exocytosis and reveals a direct interaction of Munc18-1 with Rab3. Biochem. J. 409: 407-16
-
(2008)
Biochem. J.
, vol.409
, pp. 407-416
-
-
Graham, M.E.1
Handley, M.T.2
Barclay, J.W.3
Ciufo, L.F.4
Barrow, S.L.5
-
56
-
-
38949089701
-
Binding of the Munc13-1MUN domain to membrane-anchored SNARE complexes
-
Guan R, Dai H, Rizo J. 2008. Binding of the Munc13-1MUN domain to membrane-anchored SNARE complexes. Biochemistry 47: 1474-81
-
(2008)
Biochemistry
, vol.47
, pp. 1474-1481
-
-
Guan, R.1
Dai, H.2
Rizo, J.3
-
57
-
-
34548263167
-
Open Syntaxin docks synaptic vesicles
-
Hammarlund M, Palfreyman MT, Watanabe S, Olsen S, Jorgensen EM. 2007. Open Syntaxin docks synaptic vesicles. PLOS Biol. 5: e198
-
(2007)
PLOS Biol.
, vol.5
, pp. e198
-
-
Hammarlund, M.1
Palfreyman, M.T.2
Watanabe, S.3
Olsen, S.4
Jorgensen, E.M.5
-
58
-
-
80655149438
-
Munc18-1 domain-1 controls vesicle docking and secretion by interacting with Syntaxin-1 and chaperoning it to the plasma membrane
-
Han GA, MalintanNT, SawNM, Li L, Han L, et al. 2011. Munc18-1 domain-1 controls vesicle docking and secretion by interacting with Syntaxin-1 and chaperoning it to the plasma membrane. Mol. Biol. Cell 22: 4134-49
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 4134-4149
-
-
Han, G.A.1
Malintan, N.T.2
Saw, N.M.3
Li, L.4
Han, L.5
-
59
-
-
73949143978
-
Rescue of Munc18-1 and-2 double knockdown reveals the essential functions of interaction between Munc18 and closed Syntaxin in PC12 cells
-
HanL, JiangT, Han GA, MalintanNT, XieL, et al. 2009. Rescue of Munc18-1 and-2 double knockdown reveals the essential functions of interaction between Munc18 and closed Syntaxin in PC12 cells. Mol. Biol. Cell 20: 4962-75
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 4962-4975
-
-
Han, L.1
Jiang, T.2
Han, G.A.3
Malintan, N.T.4
Xie, L.5
-
60
-
-
0030740252
-
Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy
-
Hanson PI, Roth R, Morisaki H, Jahn R, Heuser JE. 1997. Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy. Cell 90: 523-35
-
(1997)
Cell
, vol.90
, pp. 523-535
-
-
Hanson, P.I.1
Roth, R.2
Morisaki, H.3
Jahn, R.4
Heuser, J.E.5
-
61
-
-
73949147907
-
Yeast Sec1p functions before and after vesicle docking
-
Hashizume K, Cheng YS, Hutton JL, Chiu CH, Carr CM. 2009. Yeast Sec1p functions before and after vesicle docking. Mol. Biol. Cell 20: 4673-85
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 4673-4685
-
-
Hashizume, K.1
Cheng, Y.S.2
Hutton, J.L.3
Chiu, C.H.4
Carr, C.M.5
-
62
-
-
0027364502
-
Synaptic vesicle fusion complex contains unc-18 homologue bound to Syntaxin
-
Hata Y, Slaughter CA, Sudhof TC. 1993. Synaptic vesicle fusion complex contains unc-18 homologue bound to Syntaxin. Nature 366: 347-51
-
(1993)
Nature
, vol.366
, pp. 347-351
-
-
Hata, Y.1
Slaughter, C.A.2
Sudhof, T.C.3
-
63
-
-
84862630110
-
Membrane fusion intermediates via directional and full assembly of the SNARE complex
-
Hernandez JM, Stein A, Behrmann E, RiedelD, Cypionka A, et al. 2012. Membrane fusion intermediates via directional and full assembly of the SNARE complex. Science 336: 1581-84
-
(2012)
Science
, vol.336
, pp. 1581-1584
-
-
Hernandez, J.M.1
Stein, A.2
Behrmann, E.3
Riedel, D.4
Cypionka, A.5
-
64
-
-
67649884533
-
Solution and membranebound conformations of the tandem C2A and C2B domains of synaptotagmin 1. Evidence for bilayer bridging
-
Herrick DZ, Kuo W, Huang H, Schwieters CD, Ellena JF, Cafiso DS. 2009. Solution and membranebound conformations of the tandem C2A and C2B domains of synaptotagmin 1: evidence for bilayer bridging. J. Mol. Biol. 390: 913-23
-
(2009)
J. Mol. Biol.
, vol.390
, pp. 913-923
-
-
Herrick, D.Z.1
Kuo, W.2
Huang, H.3
Schwieters, C.D.4
Ellena, J.F.5
Cafiso, D.S.6
-
66
-
-
79551637409
-
Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation
-
Hu SH, Christie MP, Saez NJ, Latham CF, Jarrott R, et al. 2011. Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation. PNAS 108: 1040-45
-
(2011)
PNAS
, vol.108
, pp. 1040-1045
-
-
Hu, S.H.1
Christie, M.P.2
Saez, N.J.3
Latham, C.F.4
Jarrott, R.5
-
67
-
-
79960053907
-
Mechanism and function of synaptotagmin-mediated membrane apposition
-
Hui E, Gaffaney JD, Wang Z, Johnson CP, Evans CS, Chapman ER. 2011. Mechanism and function of synaptotagmin-mediated membrane apposition. Nat. Struct. Mol. Biol. 18: 813-21
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 813-821
-
-
Hui, E.1
Gaffaney, J.D.2
Wang, Z.3
Johnson, C.P.4
Evans, C.S.5
Chapman, E.R.6
-
68
-
-
68749083522
-
Synaptotagmin-mediated bending of the target membrane is a critical step in Ca2+-regulated fusion
-
Hui E, Johnson CP, Yao J, Dunning FM, Chapman ER. 2009. Synaptotagmin-mediated bending of the target membrane is a critical step in Ca2+-regulated fusion. Cell 138: 709-21
-
(2009)
Cell
, vol.138
, pp. 709-721
-
-
Hui, E.1
Johnson, C.P.2
Yao, J.3
Dunning, F.M.4
Chapman, E.R.5
-
69
-
-
34748846347
-
A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth
-
Huntwork S, Littleton JT. 2007. A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth. Nat. Neurosci. 10: 1235-37
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 1235-1237
-
-
Huntwork, S.1
Littleton, J.T.2
-
70
-
-
84867295592
-
Molecular machines governing exocytosis of synaptic vesicles
-
Jahn R, Fasshauer D. 2012. Molecular machines governing exocytosis of synaptic vesicles. Nature 490: 201-7
-
(2012)
Nature
, vol.490
, pp. 201-207
-
-
Jahn, R.1
Fasshauer, D.2
-
72
-
-
59849095529
-
Binding ofUNC-18 to the N-terminus of Syntaxin is essential for neurotransmission in Caenorhabditis elegans
-
Johnson JR, Ferdek P, Lian LY, Barclay JW, Burgoyne RD, Morgan A. 2009. Binding ofUNC-18 to the N-terminus of Syntaxin is essential for neurotransmission in Caenorhabditis elegans. Biochem. J. 418: 73-80
-
(2009)
Biochem. J.
, vol.418
, pp. 73-80
-
-
Johnson, J.R.1
Ferdek, P.2
Lian, L.Y.3
Barclay, J.W.4
Burgoyne, R.D.5
Morgan, A.6
-
73
-
-
84870992389
-
Complexin controls spontaneous and evoked neurotransmitter release by regulating the timing and properties of synaptotagmin activity
-
Jorquera RA, Huntwork-Rodriguez S, Akbergenova Y, ChoRW, Littleton JT. 2012. Complexin controls spontaneous and evoked neurotransmitter release by regulating the timing and properties of synaptotagmin activity. J. Neurosci. 32: 18234-45
-
(2012)
J. Neurosci.
, vol.32
, pp. 18234-18245
-
-
Jorquera, R.A.1
Huntwork-Rodriguez, S.2
Akbergenova, Y.3
Cho, R.W.4
Littleton, J.T.5
-
74
-
-
84863120538
-
C-terminal complexin sequence is selectively required for clamping and priming but not for Ca2+ triggering of synaptic exocytosis
-
Kaeser-Woo YJ, Yang X, Sudhof TC. 2012. C-terminal complexin sequence is selectively required for clamping and priming but not for Ca2+ triggering of synaptic exocytosis. J. Neurosci. 32: 2877-85
-
(2012)
J. Neurosci.
, vol.32
, pp. 2877-2885
-
-
Kaeser-Woo, Y.J.1
Yang, X.2
Sudhof, T.C.3
-
75
-
-
35348925451
-
V-SNARE actions during Ca2+-triggered exocytosis
-
Kesavan J, Borisovska M, Bruns D. 2007. v-SNARE actions during Ca2+-triggered exocytosis. Cell 131: 351-63
-
(2007)
Cell
, vol.131
, pp. 351-363
-
-
Kesavan, J.1
Borisovska, M.2
Bruns, D.3
-
76
-
-
36049049393
-
Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to Syntaxin-1Nterminus
-
Khvotchev M, Dulubova I, Sun J, Dai H, Rizo J, Sudhof TC. 2007. Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to Syntaxin-1Nterminus. J. Neurosci. 27: 12147-55
-
(2007)
J. Neurosci.
, vol.27
, pp. 12147-12155
-
-
Khvotchev, M.1
Dulubova, I.2
Sun, J.3
Dai, H.4
Rizo, J.5
Sudhof, T.C.6
-
77
-
-
0036712185
-
Membrane topologies of neuronal SNARE folding intermediates
-
Kim CS, Kweon DH, Shin YK. 2002. Membrane topologies of neuronal SNARE folding intermediates. Biochemistry 41: 10928-33
-
(2002)
Biochemistry
, vol.41
, pp. 10928-10933
-
-
Kim, C.S.1
Kweon, D.H.2
Shin, Y.K.3
-
78
-
-
84862778677
-
Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs
-
Kim JY, Choi BK, Choi MG, Kim SA, Lai Y, et al. 2012. Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs. EMBO J. 31: 2144-55
-
(2012)
EMBO J.
, vol.31
, pp. 2144-2155
-
-
Kim, J.Y.1
Choi, B.K.2
Choi, M.G.3
Kim, S.A.4
Lai, Y.5
-
79
-
-
79961024212
-
Complexin cross-links prefusion SNAREs into a zigzag array
-
Kummel D, Krishnakumar SS, Radoff DT, Li F, Giraudo CG, et al. 2011. Complexin cross-links prefusion SNAREs into a zigzag array. Nat. Struct. Mol. Biol. 18: 927-33
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 927-933
-
-
Kummel, D.1
Krishnakumar, S.S.2
Radoff, D.T.3
Li, F.4
Giraudo, C.G.5
-
80
-
-
79961082568
-
In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release
-
KyoungM, Srivastava A, Zhang Y, Diao J, Vrljic M, et al. 2011. In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release. PNAS 108: E304-13
-
(2011)
PNAS
, vol.108
, pp. E304-E313
-
-
Kyoung, M.1
Srivastava, A.2
Zhang, Y.3
Diao, J.4
Vrljic, M.5
-
81
-
-
78650913081
-
Synaptotagmin 1 and SNAREs form a complex that is structurally heterogeneous
-
Lai AL, HuangH, Herrick DZ, Epp N, CafisoDS. 2011. Synaptotagmin 1 and SNAREs form a complex that is structurally heterogeneous. J. Mol. Biol. 405: 696-706
-
(2011)
J. Mol. Biol.
, vol.405
, pp. 696-706
-
-
Lai, A.L.1
Huang, H.2
Herrick, D.Z.3
Epp, N.4
Cafiso, D.S.5
-
82
-
-
84921817984
-
Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms
-
Lai Y, Diao J, Cipriano DJ, Zhang Y, Pfuetzner RA, et al. 2014. Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms. eLife 3: e03756
-
(2014)
ELife
, vol.3
, pp. e03756
-
-
Lai, Y.1
Diao, J.2
Cipriano, D.J.3
Zhang, Y.4
Pfuetzner, R.A.5
-
83
-
-
84872850714
-
Fusion pore formation and expansion induced by Ca2+ and synaptotagmin 1
-
Lai Y, Diao J, Liu Y, Ishitsuka Y, Su Z, et al. 2013. Fusion pore formation and expansion induced by Ca2+ and synaptotagmin 1. PNAS 110: 1333-38
-
(2013)
PNAS
, vol.110
, pp. 1333-1338
-
-
Lai, Y.1
Diao, J.2
Liu, Y.3
Ishitsuka, Y.4
Su, Z.5
-
84
-
-
84858328639
-
The importance of an asymmetric distribution of acidic lipids for synaptotagmin 1 function as a Ca2+ sensor
-
Lai Y, Shin YK. 2012. The importance of an asymmetric distribution of acidic lipids for synaptotagmin 1 function as a Ca2+ sensor. Biochem. J. 443: 223-29
-
(2012)
Biochem. J.
, vol.443
, pp. 223-229
-
-
Lai, Y.1
Shin, Y.K.2
-
85
-
-
77952231768
-
Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1
-
Lee HK, Yang Y, Su Z, Hyeon C, Lee TS, et al. 2010. Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1. Science 328: 760-63
-
(2010)
Science
, vol.328
, pp. 760-763
-
-
Lee, H.K.1
Yang, Y.2
Su, Z.3
Hyeon, C.4
Lee, T.S.5
-
86
-
-
84871811311
-
Genetic analysis of synaptotagmin C2 domain specificity in regulating spontaneous and evoked neurotransmitter release
-
Lee J, Guan Z, Akbergenova Y, Littleton JT. 2013. Genetic analysis of synaptotagmin C2 domain specificity in regulating spontaneous and evoked neurotransmitter release. J. Neurosci. 33: 187-200
-
(2013)
J. Neurosci.
, vol.33
, pp. 187-200
-
-
Lee, J.1
Guan, Z.2
Akbergenova, Y.3
Littleton, J.T.4
-
87
-
-
84897691703
-
A half-zippered SNARE complex represents a functional intermediate in membrane fusion
-
Li F, Kummel D, Coleman J, Reinisch KM, Rothman JE, Pincet F. 2014. A half-zippered SNARE complex represents a functional intermediate in membrane fusion. J. Am. Chem. Soc. 136: 3456-64
-
(2014)
J. Am. Chem. Soc.
, vol.136
, pp. 3456-3464
-
-
Li, F.1
Kummel, D.2
Coleman, J.3
Reinisch, K.M.4
Rothman, J.E.5
Pincet, F.6
-
88
-
-
34948875856
-
Energetics and dynamics of SNAREpin folding across lipid bilayers
-
Li F, Pincet F, Perez E, Eng WS, Melia TJ, et al. 2007. Energetics and dynamics of SNAREpin folding across lipid bilayers. Nat. Struct. Mol. Biol. 14: 890-96
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 890-896
-
-
Li, F.1
Pincet, F.2
Perez, E.3
Eng, W.S.4
Melia, T.J.5
-
89
-
-
80054056038
-
The crystal structure of a Munc13 C-terminal module exhibits a remarkable similarity to vesicle tethering factors
-
Li W, Ma C, Guan R, Xu Y, Tomchick DR, Rizo J. 2011. The crystal structure of a Munc13 C-terminal module exhibits a remarkable similarity to vesicle tethering factors. Structure 19: 1443-55
-
(2011)
Structure
, vol.19
, pp. 1443-1455
-
-
Li, W.1
Ma, C.2
Guan, R.3
Xu, Y.4
Tomchick, D.R.5
Rizo, J.6
-
90
-
-
65449128209
-
Single molecule measurements of interaction free energies between the proteins within binary and ternary SNARE complexes
-
Liu W, Montana V, Parpura V, Mohideen U. 2009. Single molecule measurements of interaction free energies between the proteins within binary and ternary SNARE complexes. J. Nanoneurosci. 1: 120-29
-
(2009)
J. Nanoneurosci.
, vol.1
, pp. 120-129
-
-
Liu, W.1
Montana, V.2
Parpura, V.3
Mohideen, U.4
-
91
-
-
77955861788
-
SNAREs: Could they be the answer to an energy landscape riddle in exocytosis?
-
LiuW, Parpura V. 2010. SNAREs: could they be the answer to an energy landscape riddle in exocytosis? Sci. World J. 10: 1258-68
-
(2010)
Sci. World J.
, vol.10
, pp. 1258-1268
-
-
Liu, W.1
Parpura, V.2
-
92
-
-
59449087443
-
Synaptotagmin-1 utilizes membrane bending and SNARE binding to drive fusion pore expansion
-
Lynch KL, Gerona RR, Kielar DM, Martens S, McMahon HT, Martin TF. 2008. Synaptotagmin-1 utilizes membrane bending and SNARE binding to drive fusion pore expansion. Mol. Biol. Cell 19: 5093-103
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 5093-5103
-
-
Lynch, K.L.1
Gerona, R.R.2
Kielar, D.M.3
Martens, S.4
McMahon, H.T.5
Martin, T.F.6
-
93
-
-
85027945821
-
Munc13 mediates the transition from the closed Syntaxin-Munc18 complex to the SNARE complex
-
Ma C, Li W, Xu Y, Rizo J. 2011. Munc13 mediates the transition from the closed Syntaxin-Munc18 complex to the SNARE complex. Nat. Struct. Mol. Biol. 18: 542-49
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 542-549
-
-
Ma, C.1
Li, W.2
Xu, Y.3
Rizo, J.4
-
94
-
-
84872802734
-
Reconstitution of the vital functions ofMunc18 and Munc13 in neurotransmitter release
-
Ma C, Su L, Seven AB, Xu Y, Rizo J. 2013. Reconstitution of the vital functions ofMunc18 and Munc13 in neurotransmitter release. Science 339: 421-25
-
(2013)
Science
, vol.339
, pp. 421-425
-
-
Ma, C.1
Su, L.2
Seven, A.B.3
Xu, Y.4
Rizo, J.5
-
95
-
-
0037130255
-
The C2BCa2+-binding motif of synaptotagmin is required for synaptic transmission in vivo
-
Mackler JM, Drummond JA, Loewen CA, Robinson IM, Reist NE. 2002. The C2BCa2+-binding motif of synaptotagmin is required for synaptic transmission in vivo. Nature 418: 340-44
-
(2002)
Nature
, vol.418
, pp. 340-344
-
-
Mackler, J.M.1
Drummond, J.A.2
Loewen, C.A.3
Robinson, I.M.4
Reist, N.E.5
-
97
-
-
84864878312
-
Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release
-
Malsam J, Parisotto D, Bharat TA, Scheutzow A, Krause JM, et al. 2012. Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release. EMBO J. 31: 3270-81
-
(2012)
EMBO J.
, vol.31
, pp. 3270-3281
-
-
Malsam, J.1
Parisotto, D.2
Bharat, T.A.3
Scheutzow, A.4
Krause, J.M.5
-
98
-
-
34249933061
-
How synaptotagmin promotes membrane fusion
-
Martens S, Kozlov MM, McMahon HT. 2007. How synaptotagmin promotes membrane fusion. Science 316: 1205-8
-
(2007)
Science
, vol.316
, pp. 1205-1208
-
-
Martens, S.1
Kozlov, M.M.2
McMahon, H.T.3
-
99
-
-
79151478184
-
Complexin has opposite effects on two modes of synaptic vesicle fusion
-
Martin JA, Hu Z, Fenz KM, Fernandez J, Dittman JS. 2011. Complexin has opposite effects on two modes of synaptic vesicle fusion. Curr. Biol. 21: 97-105
-
(2011)
Curr. Biol.
, vol.21
, pp. 97-105
-
-
Martin, J.A.1
Hu, Z.2
Fenz, K.M.3
Fernandez, J.4
Dittman, J.S.5
-
100
-
-
58849164361
-
Complexin controls the force transfer from SNARE complexes to membranes in fusion
-
Maximov A, Tang J, Yang X, Pang ZP, Sudhof TC. 2009. Complexin controls the force transfer from SNARE complexes to membranes in fusion. Science 323: 516-21
-
(2009)
Science
, vol.323
, pp. 516-521
-
-
Maximov, A.1
Tang, J.2
Yang, X.3
Pang, Z.P.4
Sudhof, T.C.5
-
101
-
-
0029980441
-
Sec18p (NSF)-driven release of Sec17p (SNAP) can precede docking and fusion of yeast vacuoles
-
Mayer A, Wickner W, Haas A. 1996. Sec18p (NSF)-driven release of Sec17p (SNAP) can precede docking and fusion of yeast vacuoles. Cell 85: 83-94
-
(1996)
Cell
, vol.85
, pp. 83-94
-
-
Mayer, A.1
Wickner, W.2
Haas, A.3
-
102
-
-
0028880456
-
Complexins: Cytosolic proteins that regulate SNAP receptor function
-
McMahon HT, Missler M, Li C, Sudhof TC. 1995. Complexins: cytosolic proteins that regulate SNAP receptor function. Cell 83: 111-19
-
(1995)
Cell
, vol.83
, pp. 111-119
-
-
McMahon, H.T.1
Missler, M.2
Li, C.3
Sudhof, T.C.4
-
103
-
-
84860511697
-
Munc18-1mutations that strongly impair SNARE-complex binding support normal synaptic transmission
-
Meijer M, Burkhardt P, deWit H, Toonen RF, Fasshauer D, VerhageM. 2012. Munc18-1mutations that strongly impair SNARE-complex binding support normal synaptic transmission. EMBO J. 31: 2156-68
-
(2012)
EMBO J.
, vol.31
, pp. 2156-2168
-
-
Meijer, M.1
Burkhardt, P.2
Dewit, H.3
Toonen, R.F.4
Fasshauer, D.5
Verhage, M.6
-
104
-
-
49149131497
-
Reconstitutedmembrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones
-
MimaJ, HickeyCM, XuH, Jun Y, WicknerW. 2008. Reconstitutedmembrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones. EMBO J. 27: 2031-42
-
(2008)
EMBO J.
, vol.27
, pp. 2031-2042
-
-
Mima, J.1
Hickey, C.M.2
Xu, H.3
Jun, Y.4
Wickner, W.5
-
105
-
-
84877779303
-
Mechanical unzipping and rezipping of a single SNARE complex reveals hysteresis as a force-generating mechanism
-
Min D, Kim K, Hyeon C, Cho YH, Shin YK, Yoon TY. 2013. Mechanical unzipping and rezipping of a single SNARE complex reveals hysteresis as a force-generating mechanism. Nat. Commun. 4: 1705
-
(2013)
Nat. Commun.
, vol.4
, pp. 1705
-
-
Min, D.1
Kim, K.2
Hyeon, C.3
Cho, Y.H.4
Shin, Y.K.5
Yoon, T.Y.6
-
106
-
-
0034704771
-
Three-dimensional structure of the neuronal-Sec1-Syntaxin 1a complex
-
Misura KM, Scheller RH, Weis WI. 2000. Three-dimensional structure of the neuronal-Sec1-Syntaxin 1a complex. Nature 404: 355-62
-
(2000)
Nature
, vol.404
, pp. 355-362
-
-
Misura, K.M.1
Scheller, R.H.2
Weis, W.I.3
-
107
-
-
77958163770
-
Fast vesicle fusion in living cells requires at least three SNARE complexes
-
Mohrmann R, de Wit H, Verhage M, Neher E, Sorensen JB. 2010. Fast vesicle fusion in living cells requires at least three SNARE complexes. Science 330: 502-5
-
(2010)
Science
, vol.330
, pp. 502-505
-
-
Mohrmann, R.1
De Wit, H.2
Verhage, M.3
Neher, E.4
Sorensen, J.B.5
-
108
-
-
0031709722
-
Regulation of SNARE complex assembly by an N-terminal domain of the t-SNARE Sso1p
-
Nicholson KL, Munson M, Miller RB, Filip TJ, Fairman R, Hughson FM. 1998. Regulation of SNARE complex assembly by an N-terminal domain of the t-SNARE Sso1p. Nat. Struct. Biol. 5: 793-802
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 793-802
-
-
Nicholson, K.L.1
Munson, M.2
Miller, R.B.3
Filip, T.J.4
Fairman, R.5
Hughson, F.M.6
-
109
-
-
0034733545
-
Selective interaction of complexin with the neuronal SNARE complex: Determination of the binding regions
-
Pabst S, Hazzard JW, Antonin W, Sudhof TC, Jahn R, et al. 2000. Selective interaction of complexin with the neuronal SNARE complex: determination of the binding regions. J. Biol. Chem. 275: 19808-18
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19808-19818
-
-
Pabst, S.1
Hazzard, J.W.2
Antonin, W.3
Sudhof, T.C.4
Jahn, R.5
-
110
-
-
79951529500
-
Membrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo
-
Paddock BE, Wang Z, Biela LM, Chen K, Getzy MD, et al. 2011. Membrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo. J. Neurosci. 31: 2248-57
-
(2011)
J. Neurosci.
, vol.31
, pp. 2248-2257
-
-
Paddock, B.E.1
Wang, Z.2
Biela, L.M.3
Chen, K.4
Getzy, M.D.5
-
111
-
-
84898070700
-
An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly
-
Parisotto D, Pfau M, Scheutzow A, Wild K, Mayer MP, et al. 2014. An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly. J. Biol. Chem. 289: 9639-50
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 9639-9650
-
-
Parisotto, D.1
Pfau, M.2
Scheutzow, A.3
Wild, K.4
Mayer, M.P.5
-
112
-
-
84867230114
-
Controlling synaptotagmin activity by electrostatic screening
-
Park Y, Hernandez JM, van den BG, Ahmed S, Holt M, et al. 2012. Controlling synaptotagmin activity by electrostatic screening. Nat. Struct. Mol. Biol. 19: 991-97
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 991-997
-
-
Park, Y.1
Hernandez, J.M.2
Van Den, B.G.3
Ahmed, S.4
Holt, M.5
-
113
-
-
67651160303
-
Remote homology between Munc13 MUN domain and vesicle tethering complexes
-
Pei J, Ma C, Rizo J, Grishin NV. 2009. Remote homology between Munc13 MUN domain and vesicle tethering complexes. J. Mol. Biol. 391: 509-17
-
(2009)
J. Mol. Biol.
, vol.391
, pp. 509-517
-
-
Pei, J.1
Ma, C.2
Rizo, J.3
Grishin, N.V.4
-
114
-
-
84880650864
-
Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ
-
Pertsinidis A, Mukherjee K, Sharma M, Pang ZP, Park SR, et al. 2013. Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ. PNAS 110: E2812-20
-
(2013)
PNAS
, vol.110
, pp. E2812-E2820
-
-
Pertsinidis, A.1
Mukherjee, K.2
Sharma, M.3
Pang, Z.P.4
Park, S.R.5
-
115
-
-
0031668972
-
The synaptic SNARE complex is a parallel four-stranded helical bundle
-
PoirierMA, Xiao W, Macosko JC, Chan C, Shin YK, Bennett MK. 1998. The synaptic SNARE complex is a parallel four-stranded helical bundle. Nat. Struct. Biol. 5: 765-69
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 765-769
-
-
Poirier, M.A.1
Xiao, W.2
Macosko, J.C.3
Chan, C.4
Shin, Y.K.5
Bennett, M.K.6
-
116
-
-
78651078463
-
Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex
-
Rathore SS, Bend EG, YuH, HammarlundM, Jorgensen EM, Shen J. 2010. Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex. PNAS 107: 22399-406
-
(2010)
PNAS
, vol.107
, pp. 22399-22406
-
-
Rathore, S.S.1
Bend, E.G.2
Yu, H.3
Hammarlund, M.4
Jorgensen, E.M.5
Shen, J.6
-
118
-
-
0035846908
-
Complexins regulate a late step in Ca2+-dependent neurotransmitter release
-
Reim K, Mansour M, Varoqueaux F, McMahon HT, Sudhof TC, et al. 2001. Complexins regulate a late step in Ca2+-dependent neurotransmitter release. Cell 104: 71-81
-
(2001)
Cell
, vol.104
, pp. 71-81
-
-
Reim, K.1
Mansour, M.2
Varoqueaux, F.3
McMahon, H.T.4
Sudhof, T.C.5
-
119
-
-
71149117138
-
A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1
-
Ren Y, Yip CK, Tripathi A, Huie D, Jeffrey PD, et al. 2009. A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1. Cell 139: 1119-29
-
(2009)
Cell
, vol.139
, pp. 1119-1129
-
-
Ren, Y.1
Yip, C.K.2
Tripathi, A.3
Huie, D.4
Jeffrey, P.D.5
-
120
-
-
29444436513
-
Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1
-
Rhee JS, Li LY, ShinOH, Rah JC, Rizo J, et al. 2005. Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1. PNAS 102: 18664-69
-
(2005)
PNAS
, vol.102
, pp. 18664-18669
-
-
Rhee, J.S.1
Li, L.Y.2
Shin, O.H.3
Rah, J.C.4
Rizo, J.5
-
122
-
-
0035913332
-
An open form of Syntaxin bypasses the requirement for UNC-13 in vesicle priming
-
Richmond JE, Weimer RM, Jorgensen EM. 2001. An open form of Syntaxin bypasses the requirement for UNC-13 in vesicle priming. Nature 412: 338-41
-
(2001)
Nature
, vol.412
, pp. 338-341
-
-
Richmond, J.E.1
Weimer, R.M.2
Jorgensen, E.M.3
-
123
-
-
30044443686
-
Conserved prefusion protein assembly in regulated exocytosis
-
Rickman C, Jimenez JL, GrahamME, Archer DA, Soloviev M, et al. 2006. Conserved prefusion protein assembly in regulated exocytosis. Mol. Biol. Cell 17: 283-94
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 283-294
-
-
Rickman, C.1
Jimenez, J.L.2
Graham, M.E.3
Archer, D.A.4
Soloviev, M.5
-
124
-
-
33745938170
-
Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release
-
Rizo J, Chen X, Arac D. 2006. Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release. Trends Cell Biol. 16: 339-50
-
(2006)
Trends Cell Biol.
, vol.16
, pp. 339-350
-
-
Rizo, J.1
Chen, X.2
Arac, D.3
-
126
-
-
84870232182
-
The membrane fusion enigma: SNAREs, Sec1/Munc18 proteins, and their accomplices-guilty as charged?
-
Rizo J, Sudhof TC. 2012. The membrane fusion enigma: SNAREs, Sec1/Munc18 proteins, and their accomplices-guilty as charged? Annu. Rev. Cell Dev. Biol. 28: 279-308
-
(2012)
Annu. Rev. Cell Dev. Biol.
, vol.28
, pp. 279-308
-
-
Rizo, J.1
Sudhof, T.C.2
-
127
-
-
34548822682
-
Complexin/synaptotagmin interplay controls acrosomal exocytosis
-
Roggero CM, De Blas GA, Dai H, Tomes CN, Rizo J, Mayorga LS. 2007. Complexin/synaptotagmin interplay controls acrosomal exocytosis. J. Biol. Chem. 282: 26335-43
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 26335-26343
-
-
Roggero, C.M.1
De Blas, G.A.2
Dai, H.3
Tomes, C.N.4
Rizo, J.5
Mayorga, L.S.6
-
128
-
-
33746804075
-
Hemifusion arrest by complexin is relieved by Ca2+-synaptotagmin i
-
Schaub JR, Lu X, Doneske B, Shin YK, McNew JA. 2006. Hemifusion arrest by complexin is relieved by Ca2+-synaptotagmin I. Nat. Struct. Mol. Biol. 13: 748-50
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 748-750
-
-
Schaub, J.R.1
Lu, X.2
Doneske, B.3
Shin, Y.K.4
McNew, J.A.5
-
129
-
-
80052247975
-
Resolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay
-
Schollmeier Y, Krause JM, Kreye S, Malsam J, Sollner TH. 2011. Resolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay. J. Biol. Chem. 286: 30582-90
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 30582-30590
-
-
Schollmeier, Y.1
Krause, J.M.2
Kreye, S.3
Malsam, J.4
Sollner, T.H.5
-
130
-
-
67650161468
-
A role of complexin-lipid interactions in membrane fusion
-
Seiler F, Malsam J, Krause JM, Sollner TH. 2009. A role of complexin-lipid interactions in membrane fusion. FEBS Lett. 583: 2343-8
-
(2009)
FEBS Lett.
, vol.583
, pp. 2343-2348
-
-
Seiler, F.1
Malsam, J.2
Krause, J.M.3
Sollner, T.H.4
-
131
-
-
84882767998
-
Prevalent mechanism of membrane bridging by synaptotagmin-1
-
Seven AB, Brewer KD, Shi L, Jiang QX, Rizo J. 2013. Prevalent mechanism of membrane bridging by synaptotagmin-1. PNAS 110: E3243-52
-
(2013)
PNAS
, vol.110
, pp. E3243-E3252
-
-
Seven, A.B.1
Brewer, K.D.2
Shi, L.3
Jiang, Q.X.4
Rizo, J.5
-
132
-
-
0032541943
-
Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: Does Ca2+ induce a conformational change?
-
Shao X, Fernandez I, Sudhof TC, Rizo J. 1998. Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change? Biochemistry 37: 16106-15
-
(1998)
Biochemistry
, vol.37
, pp. 16106-16115
-
-
Shao, X.1
Fernandez, I.2
Sudhof, T.C.3
Rizo, J.4
-
133
-
-
0031019191
-
Synaptotagmin-Syntaxin interaction: The C2 domain as a Ca2+-dependent electrostatic switch
-
Shao X, Li C, Fernandez I, Zhang X, Sudhof TC, Rizo J. 1997. Synaptotagmin-Syntaxin interaction: The C2 domain as a Ca2+-dependent electrostatic switch. Neuron 18: 133-42
-
(1997)
Neuron
, vol.18
, pp. 133-142
-
-
Shao, X.1
Li, C.2
Fernandez, I.3
Zhang, X.4
Sudhof, T.C.5
Rizo, J.6
-
134
-
-
77954715092
-
SNARE bundle and Syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion
-
Shen J, Rathore SS, Khandan L, Rothman JE. 2010. SNARE bundle and Syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion. J. Cell Biol. 190: 55-63
-
(2010)
J. Cell Biol.
, vol.190
, pp. 55-63
-
-
Shen, J.1
Rathore, S.S.2
Khandan, L.3
Rothman, J.E.4
-
135
-
-
33845987734
-
Selective activation of cognate SNAREpins by Sec1/Munc18 proteins
-
Shen J, Tareste DC, Paumet F, Rothman JE, Melia TJ. 2007. Selective activation of cognate SNAREpins by Sec1/Munc18 proteins. Cell 128: 183-95
-
(2007)
Cell
, vol.128
, pp. 183-195
-
-
Shen, J.1
Tareste, D.C.2
Paumet, F.3
Rothman, J.E.4
Melia, T.J.5
-
136
-
-
84863338243
-
SNARE proteins: One to fuse and three to keep the nascent fusion pore open
-
Shi L, Shen QT, Kiel A, Wang J, Wang HW, et al. 2012. SNARE proteins: one to fuse and three to keep the nascent fusion pore open. Science 335: 1355-59
-
(2012)
Science
, vol.335
, pp. 1355-1359
-
-
Shi, L.1
Shen, Q.T.2
Kiel, A.3
Wang, J.4
Wang, H.W.5
-
137
-
-
84896124772
-
Multiple conformations of a single SNAREpin between two nanodisc membranes reveal diverse pre-fusion states
-
Shin J, Lou X, Kweon DH, Shin YK. 2014. Multiple conformations of a single SNAREpin between two nanodisc membranes reveal diverse pre-fusion states. Biochem. J. 459: 95-102
-
(2014)
Biochem. J.
, vol.459
, pp. 95-102
-
-
Shin, J.1
Lou, X.2
Kweon, D.H.3
Shin, Y.K.4
-
138
-
-
70349488728
-
Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release
-
Shin OH, Xu J, Rizo J, Sudhof TC. 2009. Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release. PNAS 106: 16469-74
-
(2009)
PNAS
, vol.106
, pp. 16469-16474
-
-
Shin, O.H.1
Xu, J.2
Rizo, J.3
Sudhof, T.C.4
-
139
-
-
67649871266
-
A common molecular basis for membrane docking and functional priming of synaptic vesicles
-
Siksou L, Varoqueaux F, Pascual O, Triller A, Brose N, Marty S. 2009. A common molecular basis for membrane docking and functional priming of synaptic vesicles. Eur. J. Neurosci. 30: 49-56
-
(2009)
Eur. J. Neurosci.
, vol.30
, pp. 49-56
-
-
Siksou, L.1
Varoqueaux, F.2
Pascual, O.3
Triller, A.4
Brose, N.5
Marty, S.6
-
140
-
-
80052182436
-
Two Synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses
-
Sinha R, Ahmed S, Jahn R, Klingauf J. 2011. Two Synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses. PNAS 108: 14318-23
-
(2011)
PNAS
, vol.108
, pp. 14318-14323
-
-
Sinha, R.1
Ahmed, S.2
Jahn, R.3
Klingauf, J.4
-
141
-
-
17644416413
-
Dimerization of the exocyst protein Sec6p and its interaction with the t-SNARE Sec9p
-
Sivaram MV, Saporita JA, Furgason ML, Boettcher AJ, Munson M. 2005. Dimerization of the exocyst protein Sec6p and its interaction with the t-SNARE Sec9p. Biochemistry 44: 6302-11
-
(2005)
Biochemistry
, vol.44
, pp. 6302-6311
-
-
Sivaram, M.V.1
Saporita, J.A.2
Furgason, M.L.3
Boettcher, A.J.4
Munson, M.5
-
142
-
-
0027517462
-
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
-
Sollner T, Bennett MK, Whiteheart SW, Scheller RH, Rothman JE. 1993. A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell 75: 409-18
-
(1993)
Cell
, vol.75
, pp. 409-418
-
-
Sollner, T.1
Bennett, M.K.2
Whiteheart, S.W.3
Scheller, R.H.4
Rothman, J.E.5
-
143
-
-
70350212639
-
Conflicting views on the membrane fusion machinery and the fusion pore
-
Sorensen JB. 2009. Conflicting views on the membrane fusion machinery and the fusion pore. Annu. Rev. Cell Dev. Biol. 25: 513-37
-
(2009)
Annu. Rev. Cell Dev. Biol.
, vol.25
, pp. 513-537
-
-
Sorensen, J.B.1
-
144
-
-
33644852285
-
Sequential N-to C-terminal SNARE complex assembly drives priming and fusion of secretory vesicles
-
Sorensen JB, Wiederhold K, Muller EM, Milosevic I, Nagy G, et al. 2006. Sequential N-to C-terminal SNARE complex assembly drives priming and fusion of secretory vesicles. EMBO J. 25: 955-66
-
(2006)
EMBO J.
, vol.25
, pp. 955-966
-
-
Sorensen, J.B.1
Wiederhold, K.2
Muller, E.M.3
Milosevic, I.4
Nagy, G.5
-
145
-
-
67749120188
-
Helical extension of the neuronal SNARE complex into the membrane
-
Stein A, Weber G, Wahl MC, Jahn R. 2009. Helical extension of the neuronal SNARE complex into the membrane. Nature 460: 525-28
-
(2009)
Nature
, vol.460
, pp. 525-528
-
-
Stein, A.1
Weber, G.2
Wahl, M.C.3
Jahn, R.4
-
146
-
-
84863011035
-
Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission
-
Striegel AR, Biela LM, Evans CS, Wang Z, Delehoy JB, et al. 2012. Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission. J. Neurosci. 32: 1253-60
-
(2012)
J. Neurosci.
, vol.32
, pp. 1253-1260
-
-
Striegel, A.R.1
Biela, L.M.2
Evans, C.S.3
Wang, Z.4
Delehoy, J.B.5
-
147
-
-
84886998869
-
Neurotransmitter release: The last millisecond in the life of a synaptic vesicle
-
Sudhof TC. 2013. Neurotransmitter release: The last millisecond in the life of a synaptic vesicle. Neuron 80: 675-90
-
(2013)
Neuron
, vol.80
, pp. 675-690
-
-
Sudhof, T.C.1
-
148
-
-
58849092285
-
Membrane fusion: Grappling with SNARE and SM proteins
-
Sudhof TC, Rothman JE. 2009. Membrane fusion: grappling with SNARE and SM proteins. Science 323: 474-77
-
(2009)
Science
, vol.323
, pp. 474-477
-
-
Sudhof, T.C.1
Rothman, J.E.2
-
149
-
-
0028986240
-
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold
-
Sutton RB, Davletov BA, Berghuis AM, Sudhof TC, Sprang SR. 1995. Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold. Cell 80: 929-38
-
(1995)
Cell
, vol.80
, pp. 929-938
-
-
Sutton, R.B.1
Davletov, B.A.2
Berghuis, A.M.3
Sudhof, T.C.4
Sprang, S.R.5
-
150
-
-
3543096759
-
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution
-
Sutton RB, Fasshauer D, Jahn R, Brunger AT. 1998. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2. 4 A resolution. Nature 395: 347-53
-
(1998)
Nature
, vol.395
, pp. 347-353
-
-
Sutton, R.B.1
Fasshauer, D.2
Jahn, R.3
Brunger, A.T.4
-
151
-
-
33748605056
-
A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis
-
Tang J, Maximov A, Shin OH, Dai H, Rizo J, Sudhof TC. 2006. A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis. Cell 126: 1175-87
-
(2006)
Cell
, vol.126
, pp. 1175-1187
-
-
Tang, J.1
Maximov, A.2
Shin, O.H.3
Dai, H.4
Rizo, J.5
Sudhof, T.C.6
-
152
-
-
35748984692
-
Munc18-1 in secretion: Lonely Munc joins SNARE team and takes control
-
Toonen RF, Verhage M. 2007. Munc18-1 in secretion: lonely Munc joins SNARE team and takes control. Trends Neurosci. 30: 564-72
-
(2007)
Trends Neurosci.
, vol.30
, pp. 564-572
-
-
Toonen, R.F.1
Verhage, M.2
-
153
-
-
84900487682
-
Re-examining how complexin inhibits neurotransmitter release
-
Trimbuch T, Xu J, Flaherty D, Tomchick DR, Rizo J, Rosenmund C. 2014. Re-examining how complexin inhibits neurotransmitter release. eLife 3: e02391
-
(2014)
ELife
, vol.3
, pp. e02391
-
-
Trimbuch, T.1
Xu, J.2
Flaherty, D.3
Tomchick, D.R.4
Rizo, J.5
Rosenmund, C.6
-
154
-
-
1942520207
-
Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs
-
Tucker WC, Weber T, Chapman ER. 2004. Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs. Science 304: 435-38
-
(2004)
Science
, vol.304
, pp. 435-438
-
-
Tucker, W.C.1
Weber, T.2
Chapman, E.R.3
-
155
-
-
0032527312
-
Ca2+ binding to synaptotagmin: How many Ca2+ ions bind to the tip of a C2-domain?
-
Ubach J, Zhang X, Shao X, Sudhof TC, Rizo J. 1998. Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain? EMBO J. 17: 3921-30
-
(1998)
EMBO J
, vol.17
, pp. 3921-3930
-
-
Ubach, J.1
Zhang, X.2
Shao, X.3
Sudhof, T.C.4
Rizo, J.5
-
156
-
-
77949268363
-
One SNARE complex is sufficient for membrane fusion
-
van den Bogaart G, Holt MG, Bunt G, Riedel D, Wouters FS, Jahn R. 2010. One SNARE complex is sufficient for membrane fusion. Nat. Struct. Mol. Biol. 17: 358-64
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 358-364
-
-
Van Den Bogaart, G.1
Holt, M.G.2
Bunt, G.3
Riedel, D.4
Wouters, F.S.5
Jahn, R.6
-
157
-
-
79960048696
-
Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation
-
van den Bogaart G, Thutupalli S, Risselada JH, Meyenberg K, Holt M, et al. 2011. Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation. Nat. Struct. Mol. Biol. 18: 805-12
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 805-812
-
-
Van Den Bogaart, G.1
Thutupalli, S.2
Risselada, J.H.3
Meyenberg, K.4
Holt, M.5
-
158
-
-
0037172972
-
Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming
-
Varoqueaux F, Sigler A, Rhee JS, Brose N, Enk C, et al. 2002. Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. PNAS 99: 9037-42
-
(2002)
PNAS
, vol.99
, pp. 9037-9042
-
-
Varoqueaux, F.1
Sigler, A.2
Rhee, J.S.3
Brose, N.4
Enk, C.5
-
159
-
-
84863588143
-
Cis-and transmembrane interactions of synaptotagmin-1
-
Vennekate W, Schroder S, Lin CC, van den Bogaart G, Grunwald M, et al. 2012. Cis-and transmembrane interactions of synaptotagmin-1. PNAS 109: 11037-42
-
(2012)
PNAS
, vol.109
, pp. 11037-11042
-
-
Vennekate, W.1
Schroder, S.2
Lin, C.C.3
Van Den Bogaart, G.4
Grunwald, M.5
-
160
-
-
0034603030
-
Synaptic assembly of the brain in the absence of neurotransmitter secretion
-
Verhage M, Maia AS, Plomp JJ, Brussaard AB, Heeroma JH, et al. 2000. Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science 287: 864-69
-
(2000)
Science
, vol.287
, pp. 864-869
-
-
Verhage, M.1
Maia, A.S.2
Plomp, J.J.3
Brussaard, A.B.4
Heeroma, J.H.5
-
161
-
-
0034729298
-
SNAREpins are functionally resistant to disruption by NSF and ?
-
Weber T, Parlati F, McNew JA, Johnston RJ, Westermann B, et al. 2000. SNAREpins are functionally resistant to disruption by NSF and ?SNAP. J. Cell Biol. 149: 1063-72
-
(2000)
SNAP. J. Cell Biol.
, vol.149
, pp. 1063-1072
-
-
Weber, T.1
Parlati, F.2
McNew, J.A.3
Johnston, R.J.4
Westermann, B.5
-
162
-
-
0032549708
-
SNAREpins: Minimal machinery for membrane fusion
-
Weber T, Zemelman BV, McNew JA, Westermann B, Gmachl M, et al. 1998. SNAREpins: minimal machinery for membrane fusion. Cell 92: 759-72
-
(1998)
Cell
, vol.92
, pp. 759-772
-
-
Weber, T.1
Zemelman, B.V.2
McNew, J.A.3
Westermann, B.4
Gmachl, M.5
-
163
-
-
33748129499
-
UNC-13 and UNC-10/rim localize synaptic vesicles to specific membrane domains
-
Weimer RM, Gracheva EO, Meyrignac O, Miller KG, Richmond JE, Bessereau JL. 2006. UNC-13 and UNC-10/rim localize synaptic vesicles to specific membrane domains. J. Neurosci. 26: 8040-47
-
(2006)
J. Neurosci.
, vol.26
, pp. 8040-8047
-
-
Weimer, R.M.1
Gracheva, E.O.2
Meyrignac, O.3
Miller, K.G.4
Richmond, J.E.5
Bessereau, J.L.6
-
164
-
-
38949211822
-
Accessory proteins stabilize the acceptor complex for Synaptobrevin, the 1.1 Syntaxin/SNAP-25 complex
-
Weninger K, BowenME, Choi UB, Chu S, Brunger AT. 2008. Accessory proteins stabilize the acceptor complex for Synaptobrevin, the 1: 1 Syntaxin/SNAP-25 complex. Structure 16: 308-20
-
(2008)
Structure
, vol.16
, pp. 308-320
-
-
Weninger, K.1
Bowen, M.E.2
Choi, U.B.3
Chu, S.4
Brunger, A.T.5
-
165
-
-
77957020175
-
Membrane fusion: Five lipids, four SNAREs, three chaperones, two nucleotides, and a Rab, all dancing in a ring on yeast vacuoles
-
WicknerW. 2010. Membrane fusion: five lipids, four SNAREs, three chaperones, two nucleotides, and a Rab, all dancing in a ring on yeast vacuoles. Annu. Rev. Cell Dev. Biol. 26: 115-36
-
(2010)
Annu. Rev. Cell Dev. Biol.
, vol.26
, pp. 115-136
-
-
Wickner, W.1
-
166
-
-
84872723646
-
Synaptic vesicles position complexin to block spontaneous fusion
-
Wragg RT, Snead D, Dong Y, Ramlall TF, Menon I, et al. 2013. Synaptic vesicles position complexin to block spontaneous fusion. Neuron 77: 323-34
-
(2013)
Neuron
, vol.77
, pp. 323-334
-
-
Wragg, R.T.1
Snead, D.2
Dong, Y.3
Ramlall, T.F.4
Menon, I.5
-
168
-
-
77953608974
-
HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion
-
Xu H, Jun Y, Thompson J, Yates J, WicknerW. 2010. HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion. EMBO J. 29: 1948-60
-
(2010)
EMBO J.
, vol.29
, pp. 1948-1960
-
-
Xu, H.1
Jun, Y.2
Thompson, J.3
Yates, J.4
Wickner, W.5
-
169
-
-
80054811004
-
A lipid-anchored SNARE supports membrane fusion
-
Xu H, Zick M, Wickner WT, Jun Y. 2011. A lipid-anchored SNARE supports membrane fusion. PNAS 108: 17325-30
-
(2011)
PNAS
, vol.108
, pp. 17325-17330
-
-
Xu, H.1
Zick, M.2
Wickner, W.T.3
Jun, Y.4
-
170
-
-
84883308384
-
Subtle interplay between synaptotagmin and complexin binding to the SNARE complex
-
Xu J, Brewer KD, Perez-Castillejos R, Rizo J. 2013. Subtle interplay between synaptotagmin and complexin binding to the SNARE complex. J. Mol. Biol. 425: 3461-75
-
(2013)
J. Mol. Biol.
, vol.425
, pp. 3461-3475
-
-
Xu, J.1
Brewer, K.D.2
Perez-Castillejos, R.3
Rizo, J.4
-
171
-
-
77749298991
-
Binding ofMunc18-1 to Synaptobrevin and to the SNARE four-helix bundle
-
Xu Y, Su L, Rizo J. 2010. Binding ofMunc18-1 to Synaptobrevin and to the SNARE four-helix bundle. Biochemistry 49: 1568-76
-
(2010)
Biochemistry
, vol.49
, pp. 1568-1576
-
-
Xu, Y.1
Su, L.2
Rizo, J.3
-
172
-
-
77951975523
-
Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity
-
Xue M, Craig TK, Xu J, Chao HT, Rizo J, Rosenmund C. 2010. Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity. Nat. Struct. Mol. Biol. 17: 568-75
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 568-575
-
-
Xue, M.1
Craig, T.K.2
Xu, J.3
Chao, H.T.4
Rizo, J.5
Rosenmund, C.6
-
173
-
-
70350772355
-
Tilting the balance between facilitatory and inhibitory functions of mammalian and Drosophila complexins orchestrates synaptic vesicle exocytosis
-
Xue M, Lin YQ, Pan H, Reim K, Deng H, et al. 2009. Tilting the balance between facilitatory and inhibitory functions of mammalian and Drosophila complexins orchestrates synaptic vesicle exocytosis. Neuron 64: 367-80
-
(2009)
Neuron
, vol.64
, pp. 367-380
-
-
Xue, M.1
Lin, Y.Q.2
Pan, H.3
Reim, K.4
Deng, H.5
-
174
-
-
55549100557
-
The Janus-faced nature of the C2B domain is fundamental for synaptotagmin-1 function
-
Xue M, Ma C, Craig TK, Rosenmund C, Rizo J. 2008. The Janus-faced nature of the C2B domain is fundamental for synaptotagmin-1 function. Nat. Struct. Mol. Biol. 15: 1160-68
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 1160-1168
-
-
Xue, M.1
Ma, C.2
Craig, T.K.3
Rosenmund, C.4
Rizo, J.5
-
175
-
-
34948901461
-
Distinct domains of complexin i differentially regulate neurotransmitter release
-
XueM, Reim K, Chen X, Chao HT, Deng H, et al. 2007. Distinct domains of complexin I differentially regulate neurotransmitter release. Nat. Struct. Mol. Biol. 14: 949-58
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 949-958
-
-
Xue, M.1
Reim, K.2
Chen, X.3
Chao, H.T.4
Deng, H.5
-
176
-
-
45549089944
-
Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system
-
XueM, Stradomska A, Chen H, Brose N, ZhangW, et al. 2008. Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system. PNAS 105: 7875-80
-
(2008)
PNAS
, vol.105
, pp. 7875-7880
-
-
Xue, M.1
Stradomska, A.2
Chen, H.3
Brose, N.4
Zhang, W.5
-
177
-
-
0036193747
-
Sly1 binds to Golgi and ER Syntaxins via a conserved N-terminal peptide motif
-
Yamaguchi T, Dulubova I, Min SW, Chen X, Rizo J, Sudhof TC. 2002. Sly1 binds to Golgi and ER Syntaxins via a conserved N-terminal peptide motif. Dev. Cell 2: 295-305
-
(2002)
Dev. Cell
, vol.2
, pp. 295-305
-
-
Yamaguchi, T.1
Dulubova, I.2
Min, S.W.3
Chen, X.4
Rizo, J.5
Sudhof, T.C.6
-
178
-
-
78649930845
-
Complexin clamps asynchronous release by blocking a secondary Ca2+ sensor via its accessory ?Helix
-
Yang X, Kaeser-Woo YJ, Pang ZP, XuW, Sudhof TC. 2010. Complexin clamps asynchronous release by blocking a secondary Ca2+ sensor via its accessory ?helix. Neuron 68: 907-20
-
(2010)
Neuron
, vol.68
, pp. 907-920
-
-
Yang, X.1
Kaeser-Woo, Y.J.2
Pang, Z.P.3
Xu, W.4
Sudhof, T.C.5
-
179
-
-
46449139821
-
Complexin andCa2+ stimulate SNARE-mediated membrane fusion
-
Yoon TY, LuX, Diao J, Lee SM, HaT, ShinYK. 2008. Complexin andCa2+ stimulate SNARE-mediated membrane fusion. Nat. Struct. Mol. Biol. 15: 707-13
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 707-713
-
-
Yoon, T.Y.1
Lu, X.2
Diao, J.3
Lee, S.M.4
Ha, T.5
Shin, Y.K.6
-
180
-
-
78049368534
-
Tethering factors as organizers of intracellular vesicular traffic
-
Yu IM, Hughson FM. 2010. Tethering factors as organizers of intracellular vesicular traffic. Annu. Rev. Cell Dev. Biol. 26: 137-56
-
(2010)
Annu. Rev. Cell Dev. Biol.
, vol.26
, pp. 137-156
-
-
Yu, I.M.1
Hughson, F.M.2
-
181
-
-
0037117938
-
Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis
-
Zhang X, Kim-MillerMJ, Fukuda M, Kowalchyk JA, Martin TF. 2002. Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis. Neuron 34: 599-611
-
(2002)
Neuron
, vol.34
, pp. 599-611
-
-
Zhang, X.1
Kim-Miller, M.J.2
Fukuda, M.3
Kowalchyk, J.A.4
Martin, T.F.5
-
182
-
-
0032497406
-
Mechanism of phospholipid binding by the C2A-domain of synaptotagmin i
-
Zhang X, Rizo J, Sudhof TC. 1998. Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I. Biochemistry 37: 12395-403
-
(1998)
Biochemistry
, vol.37
, pp. 12395-12403
-
-
Zhang, X.1
Rizo, J.2
Sudhof, T.C.3
-
183
-
-
84878242625
-
Analysis of SNARE complex/synaptotagmin-1 interactions by onedimensional NMR spectroscopy
-
Zhou A, Brewer KD, Rizo J. 2013. Analysis of SNARE complex/synaptotagmin-1 interactions by onedimensional NMR spectroscopy. Biochemistry 52: 3446-56
-
(2013)
Biochemistry
, vol.52
, pp. 3446-3456
-
-
Zhou, A.1
Brewer, K.D.2
Rizo, J.3
-
184
-
-
84885860678
-
Lipid-anchored SNAREs lacking transmembrane regions fully support membrane fusion during neurotransmitter release
-
Zhou P, Bacaj T, Yang X, Pang ZP, Sudhof TC. 2013. Lipid-anchored SNAREs lacking transmembrane regions fully support membrane fusion during neurotransmitter release. Neuron 80: 470-83
-
(2013)
Neuron
, vol.80
, pp. 470-483
-
-
Zhou, P.1
Bacaj, T.2
Yang, X.3
Pang, Z.P.4
Sudhof, T.C.5
-
185
-
-
84872866275
-
Syntaxin-1 N-peptide andHabc-domain perform distinct essential functions in synaptic vesicle fusion
-
Zhou P, Pang ZP, Yang X, Zhang Y, Rosenmund C, et al. 2013. Syntaxin-1 N-peptide andHabc-domain perform distinct essential functions in synaptic vesicle fusion. EMBO J. 32: 159-71
-
(2013)
EMBO J.
, vol.32
, pp. 159-171
-
-
Zhou, P.1
Pang, Z.P.2
Yang, X.3
Zhang, Y.4
Rosenmund, C.5
-
186
-
-
84920986272
-
A distinct tethering step is vital for vacuolemembrane fusion
-
Zick M, WicknerWT. 2014. A distinct tethering step is vital for vacuolemembrane fusion. eLife 3: e03251
-
(2014)
ELife
, vol.3
, pp. e03251
-
-
Zick, M.1
Wickner, W.T.2
|