An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-Ethylmaleimidesensitive factor attachment protein receptor) complex assembly

Journal of Biological Chemistry

Volumn 289, Issue 14, 2014, Pages 9639-9650

  Parisotto, Daniel ^a   Pfau, Maximilian ^a   Scheutzow, Andrea ^a   Wild, Klemens ^a   Mayer, Matthias P ^b   Malsam, Jörg ^a   Sinning, Irmgard ^a   Söllner, Thomas H ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; DIGITAL STORAGE; LIPID BILAYERS;

COMPLEX ASSEMBLY; HELICAL CONFORMATION; PROTEIN RECEPTORS; READILY RELEASABLE POOLS; REGULATORY PROTEIN; SINGLE-POINT MUTATION; STRUCTURAL MODELING; SYNAPTIC TRANSMISSION;

PROTEINS;

MUNC18 PROTEIN; SNARE PROTEIN; SYNAPTOBREVIN 2; SYNTAXIN 1;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; EXOCYTOSIS; LIPID BILAYER; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STRUCTURE; SYNAPSE; SYNAPSE VESICLE;

EXOCYTOSIS; MEMBRANE FUSION; MEMBRANE RECONSTITUTION; MEMBRANE TRAFFICKING; SM PROTEIN; SNARE PROTEINS; SYNAPTIC VESICLE; VAMP2/SYNAPTOBREVIN;

AMINO ACID SUBSTITUTION; ANIMALS; MUNC18 PROTEINS; MUTATION, MISSENSE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SYNTAXIN 1; VESICLE-ASSOCIATED MEMBRANE PROTEIN 2;

EID: 84898070700     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.514273     Document Type: Article

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