Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission

Journal of Neuroscience

Volumn 32, Issue 4, 2012, Pages 1253-1260

  Striegel, Amelia R ^a   Biela, Laurie M ^a   Evans, Chantell S ^b   Wang, Zhao ^b   Delehoy, Jillian B ^a   Sutton, R Bryan ^c   Chapman, Edwin R ^b   Reist, Noreen E ^a  

^a Veterinary Dentistry and Oral Surgery   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GLUTAMIC ACID; SYNAPTOTAGMIN; SYNAPTOTAGMIN I;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; C2A DOMAIN; C2B DOMAIN; CALCIUM BINDING; CIRCULAR DICHROISM; DROSOPHILA; ELECTROPHYSIOLOGY; EXCITATORY JUNCTION POTENTIAL; FEMALE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; ISOTHERMAL TITRATION CALORIMETRY; MALE; MEMBRANE FUSION; MOLECULAR MODEL; MUTATION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE ALIGNMENT; STRUCTURE ANALYSIS; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CALCIUM; CALCIUM-BINDING PROTEINS; DROSOPHILA MELANOGASTER; FEMALE; HUMANS; MALE; MICE; MOLECULAR SEQUENCE DATA; NEURAL INHIBITION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; STATIC ELECTRICITY; SYNAPTIC TRANSMISSION; SYNAPTOTAGMINS; THERMODYNAMICS;

EID: 84863011035     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4652-11.2012     Document Type: Article

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