-
1
-
-
0037184043
-
The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly
-
Antonin W, Dulubova I, Arac D, Pabst S, Plitzner J, Rizo J, Jahn R (2002) The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly.J Biol Chem 277: 36449-36456
-
(2002)
J Biol Chem
, vol.277
, pp. 36449-36456
-
-
Antonin, W.1
Dulubova, I.2
Arac, D.3
Pabst, S.4
Plitzner, J.5
Rizo, J.6
Jahn, R.7
-
2
-
-
2642573587
-
Crystal structure of the Habc domain of neuronal syntaxin from the squid Loligo pealei reveals conformational plasticity at its C-terminus
-
Bracher A, Weissenhorn W (2004) Crystal structure of the Habc domain of neuronal syntaxin from the squid Loligo pealei reveals conformational plasticity at its C-terminus.BMC Struct Biol 4: 6
-
(2004)
BMC Struct Biol
, vol.4
, pp. 6
-
-
Bracher, A.1
Weissenhorn, W.2
-
3
-
-
64749107397
-
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming
-
Deák F, Xu Y, Chang WP, Dulubova I, Khvotchev M, Liu X, Südhof TC, Rizo J (2009) Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming.J Cell Biol 184: 751-764
-
(2009)
J Cell Biol
, vol.184
, pp. 751-764
-
-
Deák, F.1
Xu, Y.2
Chang, W.P.3
Dulubova, I.4
Khvotchev, M.5
Liu, X.6
Südhof, T.C.7
Rizo, J.8
-
4
-
-
77951729758
-
Single-vesicle fusion assay reveals Munc18-1 binding to the SNARE core is sufficient for stimulating membrane fusion
-
Diao J, Su Z, Lu X, Yoon TY, Shin YK, Ha T (2010) Single-vesicle fusion assay reveals Munc18-1 binding to the SNARE core is sufficient for stimulating membrane fusion.ACS Chem Neurosci 1: 168-174
-
(2010)
ACS Chem Neurosci
, vol.1
, pp. 168-174
-
-
Diao, J.1
Su, Z.2
Lu, X.3
Yoon, T.Y.4
Shin, Y.K.5
Ha, T.6
-
5
-
-
0037422556
-
Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-1ike proteins
-
DOI 10.1073/pnas.232701299
-
Dulubova I, Yamaguchi T, Araç D, Li H, Huryeva I, Min SW, Rizo J, Südhof TC (2003) Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins.Proc Natl Acad Sci USA 100: 32-37 (Pubitemid 36078025)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.1
, pp. 32-37
-
-
Dulubova, I.1
Yamaguchi, T.2
Arac, D.3
Li, H.4
Huryeva, I.5
Min, S.-W.6
Rizo, J.7
Sudhof, T.C.8
-
6
-
-
33847326814
-
Munc18-1 binds directly to the neuronal SNARE complex
-
DOI 10.1073/pnas.0611318104
-
Dulubova I, Khvotchev M, Liu S, Huryeva I, Südhof TC, Rizo J (2007) Munc18-1 binds directly to the neuronal SNARE complex.Proc Natl Acad Sci USA 104: 2697-2702 (Pubitemid 46327942)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.8
, pp. 2697-2702
-
-
Dulubova, I.1
Khvotchev, M.2
Liu, S.3
Huryeva, I.4
Sudhof, T.C.5
Rizo, J.6
-
7
-
-
0033575749
-
A conformational switch in syntaxin during exocytosis: Role of munc18
-
DOI 10.1093/emboj/18.16.4372
-
Dulubova I, Sugita S, Hill S, Hosaka M, Fernandez I, Südhof TC, Rizo J (1999) A conformational switch in syntaxin during exocytosis: role of munc18.EMBO J 18: 4372-4382 (Pubitemid 29391247)
-
(1999)
EMBO Journal
, vol.18
, Issue.16
, pp. 4372-4382
-
-
Dulubova, I.1
Sugita, S.2
Hill, S.3
Hosaka, M.4
Fernandez, I.5
Sudhof, T.C.6
Rizo, J.7
-
8
-
-
0032544441
-
Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A
-
DOI 10.1016/S0092-8674(00)81742-0
-
Fernandez I, Ubach J, Dulubova I, Zhang X, Südhof TC, Rizo J (1998) Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A.Cell 94: 841-849 (Pubitemid 28436015)
-
(1998)
Cell
, vol.94
, Issue.6
, pp. 841-849
-
-
Fernandez, I.1
Ubach, J.2
Dulubova, I.3
Zhang, X.4
Sudhof, T.C.5
Rizo, J.6
-
9
-
-
51749100843
-
Conformational switch of syntaxin-1 controls synaptic vesicle fusion
-
Gerber SH, Rah JC, Min SW, Liu X, de Wit H, Dulubova I, Meyer AC, Rizo J, Arancillo M, Hammer RE, Verhage M, Rosenmund C, Südhof TC (2008) Conformational switch of syntaxin-1 controls synaptic vesicle fusion.Science 321: 1507-1510
-
(2008)
Science
, vol.321
, pp. 1507-1510
-
-
Gerber, S.H.1
Rah, J.C.2
Min, S.W.3
Liu, X.4
De Wit, H.5
Dulubova, I.6
Meyer, A.C.7
Rizo, J.8
Arancillo, M.9
Hammer, R.E.10
Verhage, M.11
Rosenmund, C.12
Südhof, T.C.13
-
10
-
-
34547865367
-
Munc18-1: Sequential interactions with the fusion machinery stimulate vesicle docking and priming
-
DOI 10.1523/JNEUROSCI.0658-07.2007
-
Gulyás-Kovács A, de Wit H, Milosevic I, Kochubey O, Toonen R, Klingauf J, Verhage M, Sørensen JB.(2007) Munc18-1: sequential interactions with the fusion machinery stimulate vesicle docking and priming.J Neurosci 27: 8676-8686 (Pubitemid 47254252)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.32
, pp. 8676-8686
-
-
Gulyas-Kovacs, A.1
De Wit, H.2
Milosevic, I.3
Kochubey, O.4
Toonen, R.5
Klingauf, J.6
Verhage, M.7
Sorensen, J.B.8
-
11
-
-
0027364502
-
Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin
-
Hata Y, Slaughter CA, Südhof TC (1993) Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin.Nature 366: 347-351
-
(1993)
Nature
, vol.366
, pp. 347-351
-
-
Hata, Y.1
Slaughter, C.A.2
Südhof, T.C.3
-
12
-
-
34547483062
-
Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins
-
DOI 10.1073/pnas.0701124104
-
Hu SH, Latham CF, Gee CL, James DE, Martin JL (2007) Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins.Proc Natl Acad Sci USA 104: 8773-8778 (Pubitemid 47175387)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.21
, pp. 8773-8778
-
-
Hu, S.-H.1
Latham, C.F.2
Gee, C.L.3
James, D.E.4
Martin, J.L.5
-
13
-
-
59849095529
-
Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans
-
Johnson JR, Ferdek P, Lian LY, Barclay JW, Burgoyne RD, Morgan A (2009) Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans.Biochem J 418: 73-80
-
(2009)
Biochem J
, vol.418
, pp. 73-80
-
-
Johnson, J.R.1
Ferdek, P.2
Lian, L.Y.3
Barclay, J.W.4
Burgoyne, R.D.5
Morgan, A.6
-
15
-
-
36049049393
-
Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus
-
DOI 10.1523/JNEUROSCI.3655-07.2007
-
Khvotchev M, Dulubova I, Sun J, Dai H, Rizo J, Südhof TC (2007) Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1N terminus.J Neurosci 27: 12147-12155 (Pubitemid 350085457)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.45
, pp. 12147-12155
-
-
Khvotchev, M.1
Dulubova, I.2
Sun, J.3
Dai, H.4
Rizo, J.5
Sudhof, T.C.6
-
17
-
-
85027945821
-
Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex
-
Ma C, LiW, Xu Y, Rizo J (2011) Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex.Nat Struct Mol Biol 18: 542-549
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 542-549
-
-
Ma, C.1
Li, W.2
Xu, Y.3
Rizo, J.4
-
18
-
-
33847352925
-
Monitoring synaptic transmission in primary neuronal cultures using local extracellular stimulation
-
DOI 10.1016/j.jneumeth.2006.10.009, PII S0165027006005097
-
Maximov A, Pang ZP, Tervo DG, Südhof TC (2007) Monitoring synaptic transmission in primary neuronal cultures using local extracellular stimulation.J Neurosci Methods 161: 75-87 (Pubitemid 46349250)
-
(2007)
Journal of Neuroscience Methods
, vol.161
, Issue.1
, pp. 75-87
-
-
Maximov, A.1
Pang, Z.P.2
Tervo, D.G.R.3
Sudhof, T.C.4
-
19
-
-
27844499290
-
Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release
-
DOI 10.1016/j.neuron.2005.09.006, PII S0896627305007725
-
Maximov A, Südhof TC (2005) Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release.Neuron 48: 547-554 (Pubitemid 41654677)
-
(2005)
Neuron
, vol.48
, Issue.4
, pp. 547-554
-
-
Maximov, A.1
Sudhof, T.C.2
-
20
-
-
55549102680
-
UNC-18 promotes both the anterograde trafficking and synaptic function of syntaxin
-
McEwen JM, Kaplan JM (2008) UNC-18 promotes both the anterograde trafficking and synaptic function of syntaxin.Mol Biol Cell 19: 3836-3846
-
(2008)
Mol Biol Cell
, vol.19
, pp. 3836-3846
-
-
McEwen, J.M.1
Kaplan, J.M.2
-
21
-
-
84860511697
-
Munc18-1 mutations that strongly impair SNAREcomplex binding support normal synaptic transmission
-
Meijer M, Burkhardt P, de Wit H, Toonen RF, Fasshauer D, Verhage M (2012) Munc18-1 mutations that strongly impair SNAREcomplex binding support normal synaptic transmission.EMBO J 31: 2156-2168
-
(2012)
EMBO J
, vol.31
, pp. 2156-2168
-
-
Meijer, M.1
Burkhardt, P.2
De Wit, H.3
Toonen, R.F.4
Fasshauer, D.5
Verhage, M.6
-
22
-
-
0034704771
-
Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex
-
DOI 10.1038/35006120
-
Misura KM, Scheller RH, Weis WI (2000) Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex.Nature 404: 355-362 (Pubitemid 30164329)
-
(2000)
Nature
, vol.404
, Issue.6776
, pp. 355-362
-
-
Misura, K.M.S.1
Scheller, R.H.2
Weis, W.I.3
-
24
-
-
77949721013
-
Calmodulin controls synaptic strength via presynaptic activation of calmodulin kinase II
-
Pang ZP, Cao P, Xu W, Südhof TC (2010) Calmodulin controls synaptic strength via presynaptic activation of calmodulin kinase II.J Neurosci 30: 4132-4142
-
(2010)
J Neurosci
, vol.30
, pp. 4132-4142
-
-
Pang, Z.P.1
Cao, P.2
Xu, W.3
Südhof, T.C.4
-
25
-
-
79955655872
-
Differential regulation of spontaneous and evoked neurotransmitter release at central synapses
-
Ramirez DM, Kavalali ET (2011) Differential regulation of spontaneous and evoked neurotransmitter release at central synapses.Curr Opin Neurobiol 21: 275-282
-
(2011)
Curr Opin Neurobiol
, vol.21
, pp. 275-282
-
-
Ramirez, D.M.1
Kavalali, E.T.2
-
26
-
-
78651078463
-
Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex
-
Rathore SS, Bend EG, Yu H, Hammarlund M, Jorgensen EM, Shen J (2010) Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex.Proc Natl Acad Sci USA 107: 22399-22406
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 22399-22406
-
-
Rathore, S.S.1
Bend, E.G.2
Yu, H.3
Hammarlund, M.4
Jorgensen, E.M.5
Shen, J.6
-
27
-
-
0035913332
-
An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming
-
DOI 10.1038/35085583
-
Richmond JE, Weimer RM, Jorgensen EM (2001) An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming.Nature 412: 338-341 (Pubitemid 32691847)
-
(2001)
Nature
, vol.412
, Issue.6844
, pp. 338-341
-
-
Richmond, J.E.1
Weimer, R.M.2
Jorgensen, E.M.3
-
28
-
-
34249689155
-
Functionally and spatially distinct modes of munc18-syntaxin 1 interaction
-
DOI 10.1074/jbc.M700227200
-
Rickman C, Medine CN, Bergmann A, Duncan RR (2007) Functionally and spatially distinct modes of munc18-syntaxin 1 interaction.J Biol Chem 282: 12097-12103 (Pubitemid 47100701)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.16
, pp. 12097-12103
-
-
Rickman, C.1
Medine, C.N.2
Bergmann, A.3
Duncan, R.R.4
-
30
-
-
58149361168
-
Munc18a scaffolds SNARE assembly to promote membrane fusion
-
Rodkey TL, Liu S, Barry M, McNew JA (2008) Munc18a scaffolds SNARE assembly to promote membrane fusion.Mol Biol Cell 19: 5422-5434
-
(2008)
Mol Biol Cell
, vol.19
, pp. 5422-5434
-
-
Rodkey, T.L.1
Liu, S.2
Barry, M.3
McNew, J.A.4
-
31
-
-
0030175394
-
Definition of the readily releasable pool of vesicles at hippocampal synapses
-
DOI 10.1016/S0896-6273(00)80146-4
-
Rosenmund C, Stevens CF (1996) Definition of the readily releasable pool of vesicles at hippocampal synapses.Neuron 16: 1197-1207 (Pubitemid 26227241)
-
(1996)
Neuron
, vol.16
, Issue.6
, pp. 1197-1207
-
-
Rosenmund, C.1
Stevens, C.F.2
-
32
-
-
13844266201
-
An isolated pool of vesicles recycles at rest and drives spontaneous neurotransmission
-
DOI 10.1016/j.neuron.2004.12.056
-
Sara Y, Virmani T, Deak F, Liu X, Kavalali ET (2005) An isolated pool of vesicles recycles at rest and drives spontaneous neurotransmission.Neuron 45: 563-573 (Pubitemid 40249868)
-
(2005)
Neuron
, vol.45
, Issue.4
, pp. 563-573
-
-
Sara, Y.1
Virmani, T.2
Deak, F.3
Liu, X.4
Kavalali, E.T.5
-
33
-
-
80052247975
-
Resolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay
-
Schollmeier Y, Krause JM, Kreye S, Malsam J, Sollner TH (2011) Resolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay.J Biol Chem 286: 30582-30590
-
(2011)
J Biol Chem
, vol.286
, pp. 30582-30590
-
-
Schollmeier, Y.1
Krause, J.M.2
Kreye, S.3
Malsam, J.4
Sollner, T.H.5
-
34
-
-
77954715092
-
SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion
-
Shen J, Rathore SS, Khandan L, Rothman JE (2010) SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion.J Cell Biol 190: 55-63
-
(2010)
J Cell Biol
, vol.190
, pp. 55-63
-
-
Shen, J.1
Rathore, S.S.2
Khandan, L.3
Rothman, J.E.4
-
35
-
-
33845987734
-
Selective Activation of Cognate SNAREpins by Sec1/Munc18 Proteins
-
DOI 10.1016/j.cell.2006.12.016, PII S0092867406016102
-
Shen J, Tareste DC, Paumet F, Rothman JE, Melia TJ (2007) Selective activation of cognate SNAREpins by Sec1/Munc18 proteins.Cell 128: 183-195 (Pubitemid 46048894)
-
(2007)
Cell
, vol.128
, Issue.1
, pp. 183-195
-
-
Shen, J.1
Tareste, D.C.2
Paumet, F.3
Rothman, J.E.4
Melia, T.J.5
-
36
-
-
80655128120
-
Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex
-
Shi L, Kümmel D, Coleman J, Melia TJ, Giraudo CG (2011) Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex.Mol Biol Cell 22: 4150-4160
-
(2011)
Mol Biol Cell
, vol.22
, pp. 4150-4160
-
-
Shi, L.1
Kümmel, D.2
Coleman, J.3
Melia, T.J.4
Giraudo, C.G.5
-
37
-
-
70350212639
-
Conflicting views on the membrane fusion machinery and the fusion pore
-
Sørensen JB (2009) Conflicting views on the membrane fusion machinery and the fusion pore.Annu Rev Cell Dev Biol 25: 513-537
-
(2009)
Annu Rev Cell Dev Biol
, vol.25
, pp. 513-537
-
-
Sørensen, J.B.1
-
39
-
-
58849092285
-
Membrane fusion: Grappling with SNARE and SM proteins
-
Südhof TC, Rothman JE (2009) Membrane fusion: grappling with SNARE and SM proteins.Science 323: 474-477
-
(2009)
Science
, vol.323
, pp. 474-477
-
-
Südhof, T.C.1
Rothman, J.E.2
-
40
-
-
36749078085
-
2+-sensor model for neurotransmitter release in a central synapse
-
DOI 10.1038/nature06308, PII NATURE06308
-
2+-sensor model for neurotransmitter release in a central synapse.Nature 450: 676-682 (Pubitemid 350207687)
-
(2007)
Nature
, vol.450
, Issue.7170
, pp. 676-682
-
-
Sun, J.1
Pang, Z.P.2
Qin, D.3
Fahim, A.T.4
Adachi, R.5
Sudhof, T.C.6
-
41
-
-
66149123268
-
Partitioning the synaptic landscape: Distinct microdomains for spontaneous and spike-triggered neurotransmission
-
Sutton MA, Schuman EM (2009) Partitioning the synaptic landscape: distinct microdomains for spontaneous and spike-triggered neurotransmission.Sci Signal 2: pe19
-
(2009)
Sci Signal
, vol.2
-
-
Sutton, M.A.1
Schuman, E.M.2
-
42
-
-
40649084835
-
SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes
-
DOI 10.1073/pnas.0712125105
-
Tareste D, Shen J, Melia TJ, Rothman JE (2008) SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes.Proc Natl Acad Sci USA 105: 2380-2385 (Pubitemid 351520522)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.7
, pp. 2380-2385
-
-
Tareste, D.1
Shen, J.2
Melia, T.J.3
Rothman, J.E.4
-
43
-
-
0034603030
-
Synaptic assembly of the brain in the absence of neurotransmitter secretion
-
DOI 10.1126/science.287.5454.864
-
Verhage M, Maia AS, Plomp JJ, Brussaard AB, Heeroma JH, Vermeer H, Toonen RF, Hammer RE, van den Berg TK, Missler M, Geuze HJ, Südhof TC (2000) Synaptic assembly of the brain in the absence of neurotransmitter secretion.Science 287: 864-869 (Pubitemid 30084331)
-
(2000)
Science
, vol.287
, Issue.5454
, pp. 864-869
-
-
Verhage, M.1
Maia, A.S.2
Plomp, J.J.3
Brussaard, A.B.4
Heeroma, J.H.5
Vermeer, H.6
Toonen, R.F.7
Hammer, R.E.8
Van Den Berg, T.K.9
Missler, M.10
Geuze, H.J.11
Sudhof, T.C.12
-
44
-
-
0036193747
-
Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif
-
DOI 10.1016/S1534-5807(02)00125-9
-
Yamaguchi T, Dulubova I, Min SW, Chen X, Rizo J, Südhof TC (2002) Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif.Dev Cell 2: 295-305 (Pubitemid 34266115)
-
(2002)
Developmental Cell
, vol.2
, Issue.3
, pp. 295-305
-
-
Yamaguchi, T.1
Dulubova, I.2
Min, S.-W.3
Chen, X.4
Rizo, J.5
Sudhof, T.C.6
|