The C2B Ca2+-binding motif of synaptotagmin is required for synaptic transmission in vivo

Nature

Volumn 418, Issue 6895, 2002, Pages 340-344

  Mackler, J M ^a   Drummond, J A ^b   Loewen, C A ^a   Robinson, I M ^b   Reist, N E ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; GENES; MOLECULES; NEUROLOGY;

NEUROTRANSMITTERS;

PROTEINS;

ASPARTIC ACID; CALCIUM ION; SYNAPTOTAGMIN;

BIOLOGY; GENETICS; MUTATION;

ARTICLE; BINDING SITE; CALCIUM BINDING; CALCIUM SIGNALING; CONTROLLED STUDY; CYTOPLASM; DROSOPHILA; GENE DELETION; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTEIN MOTIF; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BINDING SITES; CALCIUM; CALCIUM SIGNALING; CALCIUM-BINDING PROTEINS; DROSOPHILA MELANOGASTER; ELECTROPHYSIOLOGY; LARVA; LIPOSOMES; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NERVE TISSUE PROTEINS; NERVOUS SYSTEM; NEUROTRANSMITTER AGENTS; PROTEIN STRUCTURE, TERTIARY; SYNAPSES; SYNAPTIC TRANSMISSION; SYNAPTOTAGMINS;

EID: 0037130255     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature00846     Document Type: Article

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