Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms

eLife

Volumn 3, Issue , 2014, Pages e03756-

  Lai, Ying ^a   Diao, Jiajie ^a   Cipriano, Daniel J ^a   Zhang, Yunxiang ^a   Pfuetzner, Richard A ^a   Padolina, Mark S ^a   Brunger, Axel T ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

complexin; membrane fusion; neurotransmitter release; SNARE; synaptic vesicle fusion; synaptotagmin

Indexed keywords

CALCIUM; COMPLEXIN I; NERVE PROTEIN; PROTEIN BINDING; RECOMBINANT PROTEIN; SNAP25 PROTEIN, RAT; STX1A PROTEIN, RAT; SYNAPTOBREVIN 2; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNAPTOTAGMIN I; SYNTAXIN 1; SYT1 PROTEIN, RAT; VAMP2 PROTEIN, RAT; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL; BIOASSAY; BIOLOGICAL MODEL; CHEMISTRY; CYTOLOGY; ESCHERICHIA COLI; EXOCYTOSIS; GENE EXPRESSION; GENETICS; MEMBRANE FUSION; METABOLISM; MUTATION; NERVE CELL; PROTEIN REFOLDING; PROTEIN TERTIARY STRUCTURE; RAT; SYNAPSE VESICLE; TRANSPORT AT THE CELLULAR LEVEL;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; BIOLOGICAL ASSAY; BIOLOGICAL TRANSPORT; CALCIUM; ESCHERICHIA COLI; EXOCYTOSIS; GENE EXPRESSION; MEMBRANE FUSION; MODELS, BIOLOGICAL; MUTATION; NERVE TISSUE PROTEINS; NEURONS; PROTEIN BINDING; PROTEIN REFOLDING; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; SYNAPTIC VESICLES; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25; SYNAPTOTAGMIN I; SYNTAXIN 1; VESICLE-ASSOCIATED MEMBRANE PROTEIN 2;

EID: 84921817984     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.03756     Document Type: Article

References (0)