Re-examining how complexin inhibits neurotransmitter release: SNARE complex insertion or electrostatic hindrance?

eLife

Volumn 2014, Issue 3, 2014, Pages

  Trimbuch, Thorsten ^a   Xu, Junjie ^b   Flaherty, David ^b   Tomchick, Diana R ^b   Rizo, Josep ^b,c   Rosenmund, Christian ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEXIN; COMPLEXIN I; CPXI PROTEIN; PEPTIDES AND PROTEINS; SNARE PROTEIN; SYNAPTOBREVIN; SYNTAXIN 1; UNCLASSIFIED DRUG; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; NERVE PROTEIN; NITROGEN; SYNAPSIN; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL FUSION; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ELECTROPHYSIOLOGY; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; ISOTHERMAL TITRATION CALORIMETRY; NERVE CELL CULTURE; NEUROTRANSMITTER RELEASE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STATIC ELECTRICITY; SYNAPSE VESICLE; WESTERN BLOTTING; WHOLE CELL PATCH CLAMP; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL MEMBRANE; CHEMISTRY; CYTOLOGY; ESCHERICHIA COLI; GENE VECTOR; GENETICS; HIPPOCAMPUS; LENTIVIRINAE; METABOLISM; MOLECULAR MODEL; MOUSE; NERVE CELL; PROMOTER REGION; RAT;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CELL MEMBRANE; CELLS, CULTURED; ESCHERICHIA COLI; GENETIC VECTORS; HIPPOCAMPUS; HUMANS; LENTIVIRUS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; NEURONS; NEUROTRANSMITTER AGENTS; NITROGEN ISOTOPES; PROMOTER REGIONS, GENETIC; R-SNARE PROTEINS; RATS; SYNAPSINS; SYNAPTIC VESICLES; SYNTAXIN 1;

EID: 84900487682     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.02391     Document Type: Article

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