Analysis of the TGFβ-induced program in primary airway epithelial cells shows essential role of NF-ΚB/RelA signaling network in type II epithelial mesenchymal transition

BMC Genomics

Volumn 16, Issue 1, 2015, Pages

  Tian, Bing ^a,b   Li, Xueling ^b   Kalita, Mridul ^a   Widen, Steven G ^b   Yang, Jun ^a   Bhavnani, Suresh K ^a,b   Dang, Bryant ^b   Kudlicki, Andrzej ^b   Sinha, Mala ^b   Kong, Fanping ^b   Wood, Thomas G ^b   Luxon, Bruce A ^b   Brasier, Allan R ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Epithelial mesenchymal transition; Generalized linear modeling; Nuclear factor B; RNA Seq; Transcription factor enrichment; Transforming growth factor

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN; INTERFERON; SMAD PROTEIN; TELOMERASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR SNAIL1; TRANSCRIPTION FACTOR TWIST1; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; RELA PROTEIN, HUMAN;

ARTICLE; CELL IMMORTALIZATION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FN1 GENE; GENE; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETIC IDENTIFICATION; HUMAN; HUMAN CELL; INFLAMMATION; INNATE IMMUNITY; LUNG ALVEOLUS EPITHELIUM CELL; LUNG CANCER CELL LINE; NEXT GENERATION SEQUENCING; PROTEIN LOCALIZATION; RNA SEQUENCE; SIGNAL TRANSDUCTION; STATISTICAL MODEL; VIM GENE; ANTAGONISTS AND INHIBITORS; EPITHELIUM CELL; GENETICS; HIGH THROUGHPUT SEQUENCING; LUNG TUMOR; METABOLISM; PATHOLOGY; STEM CELL;

EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LUNG NEOPLASMS; NF-KAPPA B; SIGNAL TRANSDUCTION; STEM CELLS; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA;

EID: 84937212481     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-1707-x     Document Type: Article

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