Age-related macular degeneration and the role of the complement system

Molecular Immunology

Volumn 67, Issue 1, 2015, Pages 43-50

  McHarg, Selina ^a,b   Clark, Simon J ^a,b   Day, Anthony J ^c   Bishop, Paul N ^a,b,d  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d MANCHESTER ROYAL EYE HOSPITAL   (United Kingdom)

Author keywords

Age related macular degeneration; Alternative pathway; Complement system

Indexed keywords

COMPLEMENT; REACTIVE OXYGEN METABOLITE; COMPLEMENT FACTOR H; COMPLEMENT FACTOR H, HUMAN; COMPLEMENT FACTOR I;

AGE RELATED MACULAR DEGENERATION; AGING; BRUCH MEMBRANE; CHROMOSOME 1; COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM; ENVIRONMENTAL FACTOR; GENETIC RISK; GENETIC VARIABILITY; HUMAN; IMMUNOHISTOCHEMISTRY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RETINA MACULA LUTEA; REVIEW; RISK FACTOR; CHEMISTRY; GENE EXPRESSION REGULATION; GENE LOCUS; GENETICS; IMMUNOLOGY; MACULAR DEGENERATION; PATHOLOGY; PIGMENT EPITHELIUM;

BRUCH MEMBRANE; CHROMOSOMES, HUMAN, PAIR 1; COMPLEMENT ACTIVATION; COMPLEMENT C3B INACTIVATOR PROTEINS; COMPLEMENT FACTOR H; GENE EXPRESSION REGULATION; GENETIC LOCI; HUMANS; MACULAR DEGENERATION; OXIDATIVE STRESS; RETINAL PIGMENT EPITHELIUM;

EID: 84936985072     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2015.02.032     Document Type: Review

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