Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration

Ophthalmology

Volumn 119, Issue 2, 2012, Pages 339-346

  Smailhodzic, Dzenita ^a   Klaver, Caroline C W ^b   Klevering, B Jeroen ^a   Boon, Camiel J F ^a   Groenewoud, Joannes M M ^a   Kirchhof, Bernd ^c   Daha, Mohamed R ^d   Den Hollander, Anneke I ^a   Hoyng, Carel B ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF COLOGNE   (Germany)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3D; COMPLEMENT COMPONENT C5A; COMPLEMENT FACTOR H; COMPLEMENT FACTOR I; COMPLEMENT MEMBRANE ATTACK COMPLEX;

AGE RELATED MACULOPATHY SUSCEPTIBILITY 2 GENE; AGED; ALLELE; ARTICLE; CASE CONTROL STUDY; COMPLEMENT ACTIVATION; COMPLEMENT BLOOD LEVEL; CONTROLLED STUDY; FEMALE; GENE; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; AGED, 80 AND OVER; ALLELES; CASE-CONTROL STUDIES; COMPLEMENT ACTIVATION; COMPLEMENT C3; COMPLEMENT C3D; COMPLEMENT C5A; COMPLEMENT FACTOR B; COMPLEMENT FACTOR H; COMPLEMENT FACTOR I; FEMALE; GENOTYPE; HUMANS; MACULAR DEGENERATION; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; PROTEINS; RISK FACTORS;

EID: 84856511672     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2011.07.056     Document Type: Article

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