Drusen regression is associated with local changes in fundus autofluorescence in intermediate age-related macular degeneration

American Journal of Ophthalmology

Volumn 156, Issue 3, 2013, Pages

  Toy, Brian C ^a   Krishnadev, Nupura ^a   Indaram, Maanasa ^a   Cunningham, Denise ^a   Cukras, Catherine A ^a   Chew, Emily Y ^a   Wong, Wai T ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; AUTOFLUORESCENCE; DISEASE ASSOCIATION; DRUSEN; EYE FUNDUS; FUNDUS AUTOFLUORESCENCE; FUNDUS PHOTOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; OBSERVATIONAL STUDY; PHOTOGRAPHY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETINA MACULA AGE RELATED DEGENERATION;

EID: 84882275831     PISSN: 00029394     EISSN: 18791891     Source Type: Journal    
DOI: 10.1016/j.ajo.2013.04.031     Document Type: Article

References (56)

1. J.D. Gass Drusen and disciform macular detachment and degeneration Arch Ophthalmol 90 3 1973 206 217
2. F.L. Ferris, M.D. Davis, and T.E. Clemons A simplified severity scale for age-related macular degeneration: AREDS Report No. 18 Arch Ophthalmol 123 11 2005 1570 1574
3. J.P. Sarks, S.H. Sarks, and M.C. Killingsworth Evolution of soft drusen in age-related macular degeneration Eye (Lond) 8 Pt 3 1994 269 283
4. N.M. Bressler, B. Munoz, and M.G. Maguire Five-year incidence and disappearance of drusen and retinal pigment epithelial abnormalities. Waterman study Arch Ophthalmol 113 3 1995 301 308
5. R. Klein, B.E. Klein, S.C. Tomany, S.M. Meuer, and G.H. Huang Ten-year incidence and progression of age-related maculopathy: The Beaver Dam eye study Ophthalmology 109 10 2002 1767 1779
6. R.T. Smith, M.A. Sohrab, and N. Pumariega Dynamic soft drusen remodelling in age-related macular degeneration Br J Ophthalmol 94 12 2010 1618 1623
7. I.C. Frennesson, and S.E. Nilsson Effects of argon (green) laser treatment of soft drusen in early age-related maculopathy: a 6 month prospective study Br J Ophthalmol 79 10 1995 905 909
8. H.L. Little, J.M. Showman, and B.W. Brown A pilot randomized controlled study on the effect of laser photocoagulation of confluent soft macular drusen Ophthalmology 104 4 1997 623 631
9. S.H. Sarks, J.J. Arnold, J.P. Sarks, M.C. Gilles, and C.J. Walter Prophylactic perifoveal laser treatment of soft drusen Aust N Z J Ophthalmol 24 1 1996 15 26
10. M.S. Figueroa, A. Regueras, J. Bertrand, M.J. Aparicio, and M.G. Manrique Laser photocoagulation for macular soft drusen. Updated results Retina 17 5 1997 378 384
11. A. Abdelsalam, L. Del Priore, and M.A. Zarbin Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression Surv Ophthalmol 44 1 1999 1 29
12. K.I. Hartmann, M.L. Gomez, D.U. Bartsch, A.K. Schuster, and W.R. Freeman Effect of change in drusen evolution on photoreceptor inner segment/outer segment junction Retina 32 8 2012 1492 1499
13. M.L. Klein, F.L. Ferris 3rd, and J. Armstrong Retinal precursors and the development of geographic atrophy in age-related macular degeneration Ophthalmology 115 6 2008 1026 1031
14. F.B. Sallo, E. Rechtman, and T. Peto Functional aspects of drusen regression in age-related macular degeneration Br J Ophthalmol 93 10 2009 1345 1350
15. M.G. Maguire Drusen volume as a study endpoint Ophthalmology 119 7 2012 1501 1502 author reply 1502
16. Z. Yehoshua, F. Wang, P.J. Rosenfeld, F.M. Penha, W.J. Feuer, and G. Gregori Natural history of drusen morphology in age-related macular degeneration using spectral domain optical coherence tomography Ophthalmology 118 12 2011 2434 2441
17. F.C. Delori, C.K. Dorey, G. Staurenghi, O. Arend, D.G. Goger, and J.J. Weiter In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics Invest Ophthalmol Vis Sci 36 3 1995 718 729
18. A. von Ruckmann, F.W. Fitzke, and A.C. Bird Distribution of fundus autofluorescence with a scanning laser ophthalmoscope Br J Ophthalmol 79 5 1995 407 412
19. S. Schmitz-Valckenberg, M. Fleckenstein, H.P. Scholl, and F.G. Holz Fundus autofluorescence and progression of age-related macular degeneration Surv Ophthalmol 54 1 2009 96 117
20. S. Schmitz-Valckenberg, F.G. Holz, A.C. Bird, and R.F. Spaide Fundus autofluorescence imaging: review and perspectives Retina 28 3 2008 385 409
21. R.F. Spaide Fundus autofluorescence and age-related macular degeneration Ophthalmology 110 2 2003 392 399
22. S. Sternberg Biomedical image processing IEEE Computer 16 1 1983 22 34
23. Group A-REDSR The Age-Related Eye Disease Study system for classifying age-related macular degeneration from stereoscopic color fundus photographs: the Age-Related Eye Disease Study Report Number 6 Am J Ophthalmol 132 5 2001 668 681
24. T.W. Ridler, and S. Calvard Picture thresholding using an iterative selection method IEEE Trans Syst Man Cybern 8 8 1978 630 632
25. B.R. Hammond Jr., B.R. Wooten, and D.M. Snodderly Individual variations in the spatial profile of human macular pigment J Opt Soc Am A Opt Image Sci Vis 14 6 1997 1187 1196
26. A.G. Robson, J.D. Moreland, and D. Pauleikhoff Macular pigment density and distribution: comparison of fundus autofluorescence with minimum motion photometry Vision Res 43 16 2003 1765 1775
27. P.E. Kilbride, K.R. Alexander, M. Fishman, and G.A. Fishman Human macular pigment assessed by imaging fundus reflectometry Vision Res 29 6 1989 663 674
28. J.P. van de Ven, C.J. Boon, and D. Smailhodzic Short-term changes of basal laminar drusen on spectral-domain optical coherence tomography Am J Ophthalmol 154 3 2012 560 567
29. C. Cukras, E. Agron, and M.L. Klein Natural history of drusenoid pigment epithelial detachment in age-related macular degeneration: Age-Related Eye Disease Study Report No. 28 Ophthalmology 117 3 2010 489 499
30. J.M. Sparrow, A.J. Dickinson, A.M. Duke, J.R. Thompson, J.M. Gibson, and A.R. Rosenthal Seven year follow-up of age-related maculopathy in an elderly British population Eye (Lond) 11 Pt 3 1997 315 324
31. A.C. Ho, M.G. Maguire, and J. Yoken Laser-induced drusen reduction improves visual function at 1 year. Choroidal Neovascularization Prevention Trial Research Group Ophthalmology 106 7 1999 1367 1373 discussion 1374
32. Group CoA-RMDPTS The Complications of Age-Related Macular Degeneration Prevention Trial (CAPT): rationale, design and methodology Clin Trial 1 1 2004 91 107
33. J. Hsu, M.G. Maguire, and S.L. Fine Laser prophylaxis for age-related macular degeneration Can J Ophthalmol 40 3 2005 320 331
34. T.R. Friberg, P.M. Brennen, W.R. Freeman, and D.C. Musch Prophylactic treatment of age-related macular degeneration report number 2: 810-nanometer laser to eyes with drusen: bilaterally eligible patients Ophthalmic Surg Lasers Imaging 40 6 2009 530 538
35. Complications of Age-Related Macular Degeneration Prevention Trial Research Group Laser treatment in patients with bilateral large drusen: the complications of age-related macular degeneration prevention trial Ophthalmology 113 11 2006 1974 1986
36. R.T. Smith, T. Nagasaki, J.R. Sparrow, I. Barbazetto, C.C. Klaver, and J.K. Chan A method of drusen measurement based on the geometry of fundus reflectance Biomed Eng Online 2 1 2003 10
37. R.T. Smith, J.K. Chan, T. Nagasaki, J.R. Sparrow, and I. Barbazetto A method of drusen measurement based on reconstruction of fundus background reflectance Br J Ophthalmol 89 1 2005 87 91
38. R.T. Smith, J.K. Chan, and T. Nagasaki Automated detection of macular drusen using geometric background leveling and threshold selection Arch Ophthalmol 123 2 2005 200 206
39. R.T. Smith, M.A. Sohrab, and N.M. Pumariega Drusen analysis in a human-machine synergistic framework Arch Ophthalmol 129 1 2011 40 47
40. F. Delori, J.P. Greenberg, and R.L. Woods Quantitative measurements of autofluorescence with the scanning laser ophthalmoscope Invest Ophthalmol Vis Sci 52 13 2011 9379 9390
41. S. Degli Esposti, C. Egan, C. Bunce, J.D. Moreland, A.C. Bird, and A.G. Robson Macular pigment parameters in patients with macular telangiectasia (MacTel) and normal subjects: implications of a novel analysis Invest Ophthalmol Vis Sci 53 10 2012 6568 6575
42. F.G. Holz, C. Bellman, S. Staudt, F. Schutt, and H.E. Volcker Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration Invest Ophthalmol Vis Sci 42 5 2001 1051 1056
43. S. Schmitz-Valckenberg, J. Jorzik, K. Unnebrink, and F.G. Holz Analysis of digital scanning laser ophthalmoscopy fundus autofluorescence images of geographic atrophy in advanced age-related macular degeneration Graefes Arch Clin Exp Ophthalmol 240 2 2002 73 78
44. J.S. Sunness, M.D. Ziegler, and C.A. Applegate Issues in quantifying atrophic macular disease using retinal autofluorescence Retina 26 6 2006 666 672
45. S. Cherepanoff, P. McMenamin, M.C. Gillies, E. Kettle, and S.H. Sarks Bruch's membrane and choroidal macrophages in early and advanced age-related macular degeneration Br J Ophthalmol 94 7 2010 918 925
46. M.C. Killingsworth, J.P. Sarks, and S.H. Sarks Macrophages related to Bruch's membrane in age-related macular degeneration Eye (Lond) 4 Pt 4 1990 613 621
47. W. Ma, S. Coon, L. Zhao, R.N. Fariss, and W.T. Wong A2E accumulation influences retinal microglial activation and complement regulation Neurobiology Aging 34 3 2013 943 960
48. P.S. Mettu, A.R. Wielgus, S.S. Ong, and S.W. Cousins Retinal pigment epithelium response to oxidant injury in the pathogenesis of early age-related macular degeneration Mol Aspects Med 33 4 2012 376 398
49. W. Ma, L. Zhao, A.M. Fontainhas, R.N. Fariss, and W.T. Wong Microglia in the mouse retina alter the structure and function of retinal pigmented epithelial cells: a potential cellular interaction relevant to AMD PLoS One 4 11 2009 e7945
50. J.R. Sparrow, K.D. Yoon, Y. Wu, and K. Yamamoto Interpretations of fundus autofluorescence from studies of the bisretinoids of the retina Invest Ophthalmol Vis Sci 51 9 2010 4351 4357
51. M. Fleckenstein, P. Charbel Issa, H.M. Helb, S. Schmitz-Valckenberg, H.P. Scholl, and F.G. Holz Correlation of lines of increased autofluorescence in macular dystrophy and pigmented paravenous retinochoroidal atrophy by optical coherence tomography Arch Ophthalmol 126 10 2008 1461 1463
52. C.A. Cukras, W.T. Wong, R. Caruso, D. Cunningham, W. Zein, and P.A. Sieving Centrifugal expansion of fundus autofluorescence patterns in Stargardt disease over time Arch Ophthalmol 130 2 2012 171 179
53. M. Fleckenstein, P. Charbel Issa, and H.M. Helb High-resolution spectral domain-OCT imaging in geographic atrophy associated with age-related macular degeneration Invest Ophthalmol Vis Sci 49 9 2008 4137 4144
54. S. Schmitz-Valckenberg, S. Bultmann, J. Dreyhaupt, A. Bindewald, F.G. Holz, and K. Rohrschneider Fundus autofluorescence and fundus perimetry in the junctional zone of geographic atrophy in patients with age-related macular degeneration Invest Ophthalmol Vis Sci 45 12 2004 4470 4476
55. F.C. Delori, M.R. Fleckner, D.G. Goger, J.J. Weiter, and C.K. Dorey Autofluorescence distribution associated with drusen in age-related macular degeneration Invest Ophthalmol Vis Sci 41 2 2000 496 504
56. R.T. Smith, J.K. Chan, M. Busuoic, V. Sivagnanavel, A.C. Bird, and N.V. Chong Autofluorescence characteristics of early, atrophic, and high-risk fellow eyes in age-related macular degeneration Invest Ophthalmol Vis Sci 47 12 2006 5495 5504