-
1
-
-
34948891618
-
Capitalizing on Mendelian randomization to assess the effects of treatments
-
Davey Smith G. Capitalizing on Mendelian randomization to assess the effects of treatments. J R Soc Med 2007;100: 432-35.
-
(2007)
J R Soc Med
, vol.100
, pp. 432-435
-
-
Davey Smith, G.1
-
2
-
-
0037322022
-
'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?
-
Davey Smith G, Ebrahim S. 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol 2003;32:1-22.
-
(2003)
Int J Epidemiol
, vol.32
, pp. 1-22
-
-
Davey Smith, G.1
Ebrahim, S.2
-
3
-
-
79951990503
-
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
-
C-Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC). Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ 2011;342:d548.
-
(2011)
BMJ
, vol.342
-
-
-
4
-
-
84857711683
-
Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias
-
Clarke R, Bennett DA, Parish S et al. Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias. PLoS Med 2012;9: e1001177.
-
(2012)
PLoS Med
, vol.9
-
-
Clarke, R.1
Bennett, D.A.2
Parish, S.3
-
5
-
-
84862205208
-
Nonfasting glucose, ischemic heart disease, and myocardial infarction: a mendelian randomization study
-
Benn M, Tybjærg-Hansen A, McCarthy MI, Jensen GB, Grande P, Nordestgaard BG. Nonfasting glucose, ischemic heart disease, and myocardial infarction: a mendelian randomization study. J Am Coll Cardiol 2012;59:2356-65.
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 2356-2365
-
-
Benn, M.1
Tybjærg-Hansen, A.2
McCarthy, M.I.3
Jensen, G.B.4
Grande, P.5
Nordestgaard, B.G.6
-
6
-
-
84858010443
-
Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference
-
McArdle PF, Whitcomb BW, Tanner K, Mitchell BD, Shuldiner AR, Parsa A. Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference. BMC Cardiovasc Disord 2012;12:16.
-
(2012)
BMC Cardiovasc Disord
, vol.12
, pp. 16
-
-
McArdle, P.F.1
Whitcomb, B.W.2
Tanner, K.3
Mitchell, B.D.4
Shuldiner, A.R.5
Parsa, A.6
-
7
-
-
79952843139
-
Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study
-
Benn M, Tybjærg-Hansen A, Stender S, Frikke-Schmidt R, Nordestgaard BG. Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study. J Natl Cancer Inst 2011;103:508-19.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 508-519
-
-
Benn, M.1
Tybjærg-Hansen, A.2
Stender, S.3
Frikke-Schmidt, R.4
Nordestgaard, B.G.5
-
8
-
-
85017727848
-
Vitamin D levels, vitamin D insufficiency genotypes and mortality: A Mendelian randomization study
-
Trummer O, Pilz S, Hoffmann M et al. Vitamin D levels, vitamin D insufficiency genotypes and mortality: A Mendelian randomization study. Bone 2012;50:S108-09.
-
(2012)
Bone
, vol.50
, pp. S108-S109
-
-
Trummer, O.1
Pilz, S.2
Hoffmann, M.3
-
9
-
-
85027946492
-
Genetic evidence that lipoprotein(a) associates with atherosclerotic stenosis rather than venous thrombosis
-
Kamstrup PR, Tybjærg-Hansen A, Nordestgaard BG. Genetic evidence that lipoprotein(a) associates with atherosclerotic stenosis rather than venous thrombosis. Arterioscler Thromb Vasc Biol 2012;32:1732-41.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 1732-1741
-
-
Kamstrup, P.R.1
Tybjærg-Hansen, A.2
Nordestgaard, B.G.3
-
10
-
-
80055060938
-
Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies
-
Pfister R, Sharp S, Luben R et al. Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies. PLoS Med 2011; 8:e1001112.
-
(2011)
PLoS Med
, vol.8
-
-
Pfister, R.1
Sharp, S.2
Luben, R.3
-
11
-
-
84861537866
-
The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a mendelian randomisation approach
-
Nordestgaard BG, Palmer TM, Benn M et al. The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a mendelian randomisation approach. PLoS Med 2012;9:e1001212.
-
(2012)
PLoS Med
, vol.9
-
-
Nordestgaard, B.G.1
Palmer, T.M.2
Benn, M.3
-
12
-
-
80054096937
-
No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach
-
Pfister R, Barnes D, Luben R et al. No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach. Diabetologia 2011;54:2561-69.
-
(2011)
Diabetologia
, vol.54
, pp. 2561-2569
-
-
Pfister, R.1
Barnes, D.2
Luben, R.3
-
13
-
-
84874112066
-
Association of a functional single-nucleotide polymorphism in the ALDH2 gene with essential hypertension depends on drinking behavior in a Chinese Han population
-
Wang Y, Zhang Y, Zhang J et al. Association of a functional single-nucleotide polymorphism in the ALDH2 gene with essential hypertension depends on drinking behavior in a Chinese Han population. J Hum Hypertens 2013;27:181-86.
-
(2013)
J Hum Hypertens
, vol.27
, pp. 181-186
-
-
Wang, Y.1
Zhang, Y.2
Zhang, J.3
-
14
-
-
84874850513
-
The causal role of smoking on anxiety and depression-A Mendelian Randomization analysis of the HUNT study
-
Bjørngaard JH, Gunnell D, Elvestad MB et al. The causal role of smoking on anxiety and depression-A Mendelian Randomization analysis of the HUNT study. Psychol Med 2013;43:711-19.
-
(2013)
Psychol Med
, vol.43
, pp. 711-719
-
-
Bjørngaard, J.H.1
Gunnell, D.2
Elvestad, M.B.3
-
15
-
-
79960447071
-
Smoking is associated with, but does not cause, depressed mood in pregnancy-a Mendelian randomization study
-
Lewis SJ, Araya R, Davey Smith G et al. Smoking is associated with, but does not cause, depressed mood in pregnancy-a Mendelian randomization study. PLoS One 2011;6:e21689.
-
(2011)
PLoS One
, vol.6
-
-
Lewis, S.J.1
Araya, R.2
Davey Smith, G.3
-
16
-
-
84857408636
-
Alcohol consumption, genetic variants in alcohol deydrogenases, and risk of cardiovascular diseases: a prospective study and meta-analysis
-
Drogan D, Sheldrick AJ, Schütze Met al. Alcohol consumption, genetic variants in alcohol deydrogenases, and risk of cardiovascular diseases: a prospective study and meta-analysis. PLoS One 2012;7:e32176.
-
(2012)
PLoS One
, vol.7
-
-
Drogan, D.1
Sheldrick, A.J.2
Schütze, M.3
-
17
-
-
80053927120
-
Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study
-
Scott JAG, Berkley JA, Mwangi I et al. Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study. Lancet 2011;378:1316-23.
-
(2011)
Lancet
, vol.378
, pp. 1316-1323
-
-
Scott, J.A.G.1
Berkley, J.A.2
Mwangi, I.3
-
18
-
-
84886440375
-
The causal effect of malaria on stunting: a Mendelian randomization and matching approach
-
Kang H, Kreuels B, Adjei O, Krumkamp R, May J, Small DS. The causal effect of malaria on stunting: a Mendelian randomization and matching approach. Int J Epidemiol 2013;42: 1390-98.
-
(2013)
Int J Epidemiol
, vol.42
, pp. 1390-1398
-
-
Kang, H.1
Kreuels, B.2
Adjei, O.3
Krumkamp, R.4
May, J.5
Small, D.S.6
-
19
-
-
84859215358
-
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis
-
The Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R Mendelian randomization) Consortium. The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet 2012;379:1214-24.
-
(2012)
Lancet
, vol.379
, pp. 1214-1224
-
-
-
20
-
-
84859210770
-
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
-
IL6R Genetics Consortium Emerging Risk Factors Collaboration. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet 2012;379:1205-13.
-
(2012)
Lancet
, vol.379
, pp. 1205-1213
-
-
-
21
-
-
84864845456
-
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
-
Voight BF, Peloso GM, Orho-Melander M et al. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet 2012;380:572-80.
-
(2012)
Lancet
, vol.380
, pp. 572-580
-
-
Voight, B.F.1
Peloso, G.M.2
Orho-Melander, M.3
-
22
-
-
0040332008
-
Instrumental variables and the search for identification: from supply and demand to natural experiments
-
Angrist JD, Krueger AB. Instrumental variables and the search for identification: from supply and demand to natural experiments. J Econ Perspect 2001;15:69-85.
-
(2001)
J Econ Perspect
, vol.15
, pp. 69-85
-
-
Angrist, J.D.1
Krueger, A.B.2
-
23
-
-
80955177523
-
Mendelian randomization: the use of genes in instrumental variable analyses
-
von Hinke Kessler Scholder S, Davey Smith G, Lawlor DA, Propper C, Windmeijer F. Mendelian randomization: the use of genes in instrumental variable analyses. Health Econ 2011;20: 893-96.
-
(2011)
Health Econ
, vol.20
, pp. 893-896
-
-
von Hinke Kessler Scholder, S.1
Davey Smith, G.2
Lawlor, D.A.3
Propper, C.4
Windmeijer, F.5
-
24
-
-
84864812123
-
The effect of fat mass on educational attainment: examining the sensitivity to different identification strategies
-
von Hinke Kessler Scholder S, Davey Smith G, Lawlor DA, Propper C, Windmeijer F. The effect of fat mass on educational attainment: examining the sensitivity to different identification strategies. Econ Hum Biol 2012;10:405-18.
-
(2012)
Econ Hum Biol
, vol.10
, pp. 405-418
-
-
von Hinke Kessler Scholder, S.1
Davey Smith, G.2
Lawlor, D.A.3
Propper, C.4
Windmeijer, F.5
-
25
-
-
38049023073
-
Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology
-
Davey Smith G, Lawlor DA, Harbord R, Timpson NJ, Day I, Ebrahim S. Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology. PLoS Med 2008;4:1985-92.
-
(2008)
PLoS Med
, vol.4
, pp. 1985-1992
-
-
Davey Smith, G.1
Lawlor, D.A.2
Harbord, R.3
Timpson, N.J.4
Day, I.5
Ebrahim, S.6
-
26
-
-
34547682094
-
Mendelian randomization as an instrumental variable approach to causal inference
-
Didelez V, Sheehan N. Mendelian randomization as an instrumental variable approach to causal inference. Stat Methods Med Res 2007;16:309-30.
-
(2007)
Stat Methods Med Res
, vol.16
, pp. 309-330
-
-
Didelez, V.1
Sheehan, N.2
-
27
-
-
40849083720
-
Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
-
Lawlor DA, Harbord RM, Sterne JAC, Timpson NJ, Davey Smith G. Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology. Stat Med 2008; 27:1133-63.
-
(2008)
Stat Med
, vol.27
, pp. 1133-1163
-
-
Lawlor, D.A.1
Harbord, R.M.2
Sterne, J.A.C.3
Timpson, N.J.4
Davey Smith, G.5
-
28
-
-
52949135179
-
Strengthening causal inference in cardiovascular epidemiology through Mendelian randomization
-
Davey Smith G, Timpson N, Ebrahim S. Strengthening causal inference in cardiovascular epidemiology through Mendelian randomization. Ann Med 2008;12:524-41.
-
(2008)
Ann Med
, vol.12
, pp. 524-541
-
-
Davey Smith, G.1
Timpson, N.2
Ebrahim, S.3
-
29
-
-
84861827079
-
Using multiple genetic variants as instrumental variables for modifiable risk factors
-
Palmer TM, Lawlor DA, Harbord RM et al. Using multiple genetic variants as instrumental variables for modifiable risk factors. Stat Methods Med Res 2011;21: 223-42.
-
(2011)
Stat Methods Med Res
, vol.21
, pp. 223-242
-
-
Palmer, T.M.1
Lawlor, D.A.2
Harbord, R.M.3
-
30
-
-
79958821064
-
Instrumental variable estimation of causal risk ratios and causal odds ratios in mendelian randomization analyses
-
Palmer TM, Sterne JAC, Harbord RM et al. Instrumental variable estimation of causal risk ratios and causal odds ratios in mendelian randomization analyses. Am J Epidemiol 2011;173: 1392-403.
-
(2011)
Am J Epidemiol
, vol.173
, pp. 1392-1403
-
-
Palmer, T.M.1
Sterne, J.A.C.2
Harbord, R.M.3
-
31
-
-
61849142843
-
How does body fat influence bone mass in childhood? a mendelian randomisation approach
-
Timpson NJ, Sayers A, Davey Smith G, Tobias JH. How does body fat influence bone mass in childhood? a mendelian randomisation approach. J Bone Miner Res 2009:24: 522-33.
-
(2009)
J Bone Miner Res
, vol.24
, pp. 522-533
-
-
Timpson, N.J.1
Sayers, A.2
Davey Smith, G.3
Tobias, J.H.4
-
32
-
-
67649855154
-
Does greater adiposity increase blood pressure and hypertension risk? Mendelian randomization using FTO/MC4R genotype
-
Timpson N, Harbord R, Davey Smith G, Zacho J, Tybaerg-Hansen A, Nordestgaard BG. Does greater adiposity increase blood pressure and hypertension risk? Mendelian randomization using FTO/MC4R genotype. Hypertension 2009; 54:84-90.
-
(2009)
Hypertension
, vol.54
, pp. 84-90
-
-
Timpson, N.1
Harbord, R.2
Davey Smith, G.3
Zacho, J.4
Tybaerg-Hansen, A.5
Nordestgaard, B.G.6
-
33
-
-
79951677811
-
C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization
-
Timpson NJ, Nordestgaard BG, Harbord RM et al. C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization. Int J Obes 2011;35:300-08.
-
(2011)
Int J Obes
, vol.35
, pp. 300-308
-
-
Timpson, N.J.1
Nordestgaard, B.G.2
Harbord, R.M.3
-
34
-
-
75149163834
-
Unravelling the directional link between adiposity and inflammation: a bidirectional Mendelian randomisation approach
-
Welsh P, Polisecki E, Robertson M et al. Unravelling the directional link between adiposity and inflammation: a bidirectional Mendelian randomisation approach. J Clin Endocrinol Metab 2009;95:93-99.
-
(2009)
J Clin Endocrinol Metab
, vol.95
, pp. 93-99
-
-
Welsh, P.1
Polisecki, E.2
Robertson, M.3
-
35
-
-
84936776179
-
Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways
-
Burgess S, Daniel RM, Butterworth AS, Thompson SG. Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways. Int J Epidemiol 2015;44:484-95.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 484-495
-
-
Burgess, S.1
Daniel, R.M.2
Butterworth, A.S.3
Thompson, S.G.4
-
36
-
-
84927727976
-
Instrumental variable analysis with a nonlinear exposure-outcome relationship
-
Burgess S, Davies NM, Thompson SG; EPIC-Inter Act Consortium. Instrumental variable analysis with a nonlinear exposure-outcome relationship. Epidemiology 2014;25: 877-85.
-
(2014)
Epidemiology
, vol.25
, pp. 877-885
-
-
Burgess, S.1
Davies, N.M.2
Thompson, S.G.3
-
37
-
-
84922357503
-
Testing for nonlinear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits
-
Silverwood RJ, Holmes MV, Dale CE et al. Testing for nonlinear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits. Int J Epidemiol 2014;43:1781-90.
-
(2014)
Int J Epidemiol
, vol.43
, pp. 1781-1790
-
-
Silverwood, R.J.1
Holmes, M.V.2
Dale, C.E.3
-
38
-
-
84936758183
-
Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects
-
Burgess S, Thompson SG. Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects. Am J Epidemiol 2015;181:251-60.
-
(2015)
Am J Epidemiol
, vol.181
, pp. 251-260
-
-
Burgess, S.1
Thompson, S.G.2
-
39
-
-
84907828123
-
Using multivariable mendelian randomization to disentangle the causal effects of lipid fractions
-
Burgess S, Freitag DF, Khan H, Gorman DN, Thompson SG. Using multivariable mendelian randomization to disentangle the causal effects of lipid fractions. PLoS One 2014; 9:e108891.
-
(2014)
PLoS One
, vol.9
-
-
Burgess, S.1
Freitag, D.F.2
Khan, H.3
Gorman, D.N.4
Thompson, S.G.5
-
40
-
-
84928026823
-
Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: A 2 × 2 factorial mendelian randomization study
-
Ference BA, Majeed F, Penumetcha R, Flack JM, Brook RD. Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: A 2 × 2 factorial mendelian randomization study. J Am Coll Cardiol 2015;65:1552-61.
-
(2015)
J Am Coll Cardiol
, vol.65
, pp. 1552-1561
-
-
Ference, B.A.1
Majeed, F.2
Penumetcha, R.3
Flack, J.M.4
Brook, R.D.5
-
41
-
-
84936755918
-
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
-
Bowden J, Davey Smith G, Burgess S. Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. Int J Epidemiol 2015;44: 512-25.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 512-525
-
-
Bowden, J.1
Davey Smith, G.2
Burgess, S.3
-
42
-
-
84908689210
-
Association of low-density lipoprotein cholesterol-related genetic variants with aortic valve calcium and incident aortic stenosis
-
Smith JG, Luk K, Schulz CA et al. Association of low-density lipoprotein cholesterol-related genetic variants with aortic valve calcium and incident aortic stenosis. JAMA 2014;312: 1764-71.
-
(2014)
JAMA
, vol.312
, pp. 1764-1771
-
-
Smith, J.G.1
Luk, K.2
Schulz, C.A.3
-
43
-
-
81455135676
-
Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index
-
Freathy RM, Kazeem GR, Morris RW et al. Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index. Int J Epidemiol 2011;40: 1617-28.
-
(2011)
Int J Epidemiol
, vol.40
, pp. 1617-1628
-
-
Freathy, R.M.1
Kazeem, G.R.2
Morris, R.W.3
-
44
-
-
79952624880
-
Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health
-
Davey Smith G. Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health. Genes Nutr 2011;6:27-43.
-
(2011)
Genes Nutr
, vol.6
, pp. 27-43
-
-
Davey Smith, G.1
-
45
-
-
78149383523
-
Mendelian randomization for strengthening causal inference in observational studies: application to gene by environment interaction
-
Davey Smith G. Mendelian randomization for strengthening causal inference in observational studies: application to gene by environment interaction. Perspect Psychol Sci 2010;5: 527-45.
-
(2010)
Perspect Psychol Sci
, vol.5
, pp. 527-545
-
-
Davey Smith, G.1
-
46
-
-
78149381194
-
Epigenetic epidemiology of common complex disease: prospects for prediction, prevention and treatment
-
Relton CL, Davey Smith G. Epigenetic epidemiology of common complex disease: prospects for prediction, prevention and treatment. PLoS Med 2010;7:e1000356.
-
(2010)
PLoS Med
, vol.7
-
-
Relton, C.L.1
Davey Smith, G.2
-
47
-
-
84858648623
-
Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease
-
Relton CL, Davey Smith G. Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease. Int J Epidemiol 2012; 41:161-76.
-
(2012)
Int J Epidemiol
, vol.41
, pp. 161-176
-
-
Relton, C.L.1
Davey Smith, G.2
-
48
-
-
84863012079
-
Postnatal growth and DNA methylation are associated with differential gene expression of the TACSTD2 gene and childhood fat mass
-
Groom A, Potter C, Swan DC et al. Postnatal growth and DNA methylation are associated with differential gene expression of the TACSTD2 gene and childhood fat mass. Diabetes 2012;61: 391-400.
-
(2012)
Diabetes
, vol.61
, pp. 391-400
-
-
Groom, A.1
Potter, C.2
Swan, D.C.3
-
49
-
-
84928819497
-
An epigenome-wide association study of total serum immunoglobulin E concentration
-
Liang L, Willis-Owen SA, Laprise C et al. An epigenome-wide association study of total serum immunoglobulin E concentration. Nature 2015;520:670-74.
-
(2015)
Nature
, vol.520
, pp. 670-674
-
-
Liang, L.1
Willis-Owen, S.A.2
Laprise, C.3
-
50
-
-
79961186642
-
Random allocation in observational data: how small but robust effects could facilitate hypothesis-free causal inference
-
Davey Smith G. Random allocation in observational data: how small but robust effects could facilitate hypothesis-free causal inference. Epidemiology 2011;22:460-63.
-
(2011)
Epidemiology
, vol.22
, pp. 460-463
-
-
Davey Smith, G.1
-
51
-
-
84943354221
-
Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors
-
Mar 15. [Epub ahead of print.] PMID: 25773750
-
Burgess S, Scott RA, Timpson NJ, Davey Smith G, Thompson SG; EPIC-Inter Act Consortium. Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors. Eur J Epidemiol 2015, Mar 15. [Epub ahead of print.] PMID: 25773750.
-
(2015)
Eur J Epidemiol
-
-
Burgess, S.1
Scott, R.A.2
Timpson, N.J.3
Davey Smith, G.4
Thompson, S.G.5
-
52
-
-
84871969762
-
Large-scale association analysis identifies new risk loci for coronary artery disease
-
CARDIoGRAMplusC4D Consortium, Deloukas P, Kanoni S, Willenborg C et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet 2013;45: 25-33.
-
(2013)
Nat Genet
, vol.45
, pp. 25-33
-
-
Deloukas, P.1
Kanoni, S.2
Willenborg, C.3
-
53
-
-
84884793216
-
Power and sample size calculations for Mendelian randomization studies using one genetic instrument
-
Freeman G, Schooling CM, Cowling BJ. Power and sample size calculations for Mendelian randomization studies using one genetic instrument. Int J Epidemiol 2013;42:1157-63.
-
(2013)
Int J Epidemiol
, vol.42
, pp. 1157-1163
-
-
Freeman, G.1
Schooling, C.M.2
Cowling, B.J.3
-
54
-
-
79961185600
-
Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants
-
Pierce BL, Ahsan H, Vanderweele TJ. Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants. Int J Epidemiol 2011;40: 740-52.
-
(2011)
Int J Epidemiol
, vol.40
, pp. 740-752
-
-
Pierce, B.L.1
Ahsan, H.2
Vanderweele, T.J.3
-
55
-
-
84884973036
-
Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators
-
Pierce BL, Burgess S. Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators. Am J Epidemiol 2013;178:1177-84.
-
(2013)
Am J Epidemiol
, vol.178
, pp. 1177-1184
-
-
Pierce, B.L.1
Burgess, S.2
-
56
-
-
80053907554
-
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
-
International Consortium for Blood Pressure Genome-Wide Association Studies; Ehret GB, Munroe PB, Rice KM et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011;478:103-9.
-
(2011)
Nature
, vol.478
, pp. 103-109
-
-
Ehret, G.B.1
Munroe, P.B.2
Rice, K.M.3
-
57
-
-
84885840876
-
Mendelian randomization analysis with multiple genetic variants using summarized data
-
Burgess S, Butterworth A, Thompson SG. Mendelian randomization analysis with multiple genetic variants using summarized data. Genet Epidemiol 2013;37:658-65.
-
(2013)
Genet Epidemiol
, vol.37
, pp. 658-665
-
-
Burgess, S.1
Butterworth, A.2
Thompson, S.G.3
-
58
-
-
84923648340
-
A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans
-
Timpson NJ, Walter K, Min JL et al. A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans. Nature Commun 2014;5:4871.
-
(2014)
Nature Commun
, vol.5
, pp. 4871
-
-
Timpson, N.J.1
Walter, K.2
Min, J.L.3
-
59
-
-
84860431510
-
Quantitative highthroughput metabolomics: a new era in epidemiology and genetics
-
Ala-Korpela M, Kangas AJ, Soininen P. Quantitative highthroughput metabolomics: a new era in epidemiology and genetics. Genome Med 2012;4:36.
-
(2012)
Genome Med
, vol.4
, pp. 36
-
-
Ala-Korpela, M.1
Kangas, A.J.2
Soininen, P.3
-
61
-
-
79959878069
-
Metabolomics, pathway regulation and pathway discovery
-
Zhang GF, Sudhukhan S, Tochtrop GP, Brunengraber H. Metabolomics, pathway regulation and pathway discovery. J Biol Chem 2011;286:23631-5.
-
(2011)
J Biol Chem
, vol.286
, pp. 23631-23635
-
-
Zhang, G.F.1
Sudhukhan, S.2
Tochtrop, G.P.3
Brunengraber, H.4
-
62
-
-
84858790233
-
Innovation: Metabolomics: the apogee of the omics trilogy
-
Patti GJ, Yanes O, Siuzdak G. Innovation: Metabolomics: the apogee of the omics trilogy. Nat Rev Mol Cell 2012;13: 263-69.
-
(2012)
Nat Rev Mol Cell
, vol.13
, pp. 263-269
-
-
Patti, G.J.1
Yanes, O.2
Siuzdak, G.3
-
63
-
-
84862210732
-
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood
-
Davies MN, Volta M, Pidsley R et al. Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biol 2012;13:R43.
-
(2012)
Genome Biol
, vol.13
, pp. R43
-
-
Davies, M.N.1
Volta, M.2
Pidsley, R.3
-
64
-
-
84936768730
-
Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates
-
Wang Q, Kangas AJ, Soininen P et al. Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates. Int J Epidemiol 2015;44:623-37.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 623-637
-
-
Wang, Q.1
Kangas, A.J.2
Soininen, P.3
-
65
-
-
84920973132
-
Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change
-
Würtz P, Wang Q, Kangas AJ et al. Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change. PLoS Med 2014;11:e1001765.
-
(2014)
PLoS Med
, vol.11
-
-
Würtz, P.1
Wang, Q.2
Kangas, A.J.3
-
66
-
-
84902006099
-
Interrogating causal pathways linking genetic variants, small molecule metabolites and circulating lipids
-
Shin SY, Petersen AK, Wahl S et al. Interrogating causal pathways linking genetic variants, small molecule metabolites and circulating lipids. Genome Med 2014;6:25.
-
(2014)
Genome Med
, vol.6
, pp. 25
-
-
Shin, S.Y.1
Petersen, A.K.2
Wahl, S.3
-
67
-
-
84857648463
-
Genome-wide association study identifies multiple loci influencing human serum metabolite levels
-
Kettunen J, Tukiainen T, Sarin A-P et al. Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nat Genet 2012;44:269-76.
-
(2012)
Nat Genet
, vol.44
, pp. 269-276
-
-
Kettunen, J.1
Tukiainen, T.2
Sarin, A.-P.3
-
68
-
-
79953737332
-
Metabolite profiles and the risk of developing diabetes
-
Wang TJ, Larson MG, Vasan RS et al. Metabolite profiles and the risk of developing diabetes. Nat Med 2011;17:448-53.
-
(2011)
Nat Med
, vol.17
, pp. 448-453
-
-
Wang, T.J.1
Larson, M.G.2
Vasan, R.S.3
-
69
-
-
79953733693
-
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
-
Wang Z, Klipfell E, Bennett BJ et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 2011;472:57-63.
-
(2011)
Nature
, vol.472
, pp. 57-63
-
-
Wang, Z.1
Klipfell, E.2
Bennett, B.J.3
-
71
-
-
84906838227
-
Mendelian randomization: genetic anchors for causal inference in epidemiological studies
-
Davey Smith G, Hemani G. Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum Mol Genet 2014;23:R89-98.
-
(2014)
Hum Mol Genet
, vol.23
, pp. R89-R98
-
-
Davey Smith, G.1
Hemani, G.2
-
72
-
-
79251504951
-
Meetingin-the-middle using metabolic profiling-a strategy for the identification of intermediate biomarkers in cohort studies
-
Chadeau-Hyam M, Athersuch TJ, Keun HC et al. Meetingin-the-middle using metabolic profiling-a strategy for the identification of intermediate biomarkers in cohort studies. Biomarkers. 2011;16:83-88.
-
(2011)
Biomarkers
, vol.16
, pp. 83-88
-
-
Chadeau-Hyam, M.1
Athersuch, T.J.2
Keun, H.C.3
-
73
-
-
43749087841
-
Human metabolic phenotype diversity and its association with diet and blood pressure
-
Holmes E, Loo RL, Stamler J et al. Human metabolic phenotype diversity and its association with diet and blood pressure. Nature 2008;453:396-400.
-
(2008)
Nature
, vol.453
, pp. 396-400
-
-
Holmes, E.1
Loo, R.L.2
Stamler, J.3
-
74
-
-
84881545281
-
DNA methylation as a long-term biomarker of exposure to tobacco smoke
-
Shenker NS, Ueland PM, Polidoro S et al. DNA methylation as a long-term biomarker of exposure to tobacco smoke. Epidemiology 2013;24:712-16.
-
(2013)
Epidemiology
, vol.24
, pp. 712-716
-
-
Shenker, N.S.1
Ueland, P.M.2
Polidoro, S.3
-
75
-
-
84923326770
-
DNA methylation signatures link prenatal famine exposure to growth and metabolism
-
Tobi EW, Goeman JJ, Monajemi R et al. DNA methylation signatures link prenatal famine exposure to growth and metabolism. Nat Commun 2014;5:5592.
-
(2014)
Nat Commun
, vol.5
, pp. 5592
-
-
Tobi, E.W.1
Goeman, J.J.2
Monajemi, R.3
-
76
-
-
84936778746
-
Exposure to aflatoxin B1 in utero is associated with DNA methylation in white blood cells of infants in The Gambia
-
Hernandez-Vargas H, Castelino J et al. Exposure to aflatoxin B1 in utero is associated with DNA methylation in white blood cells of infants in The Gambia. Int J Epidemiol 2015;doi:10.1093/ije/dyv027.
-
(2015)
Int J Epidemiol
-
-
Hernandez-Vargas, H.1
Castelino, J.2
-
77
-
-
77649201613
-
Promises and limitations of mendelian randomization for evaluation of biomarkers
-
Glynn RJ. Promises and limitations of mendelian randomization for evaluation of biomarkers. Clin Chem 2010;56:388-90.
-
(2010)
Clin Chem
, vol.56
, pp. 388-390
-
-
Glynn, R.J.1
-
79
-
-
84871705238
-
Mendelian Randomization. Using Mendelian randomization to determine causative factors in cardiovascular disease
-
Johansen CT, Hegele RA. Mendelian Randomization. Using Mendelian randomization to determine causative factors in cardiovascular disease. J Intern Med 2013;273:44-47.
-
(2013)
J Intern Med
, vol.273
, pp. 44-47
-
-
Johansen, C.T.1
Hegele, R.A.2
-
80
-
-
77953230836
-
PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European ancestry
-
Casas JP, Ninio E, Panayiotou A, Palmen J, Cooper JA, Ricketts SL. PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European ancestry. Circulation 2010;121:2284-93.
-
(2010)
Circulation
, vol.121
, pp. 2284-2293
-
-
Casas, J.P.1
Ninio, E.2
Panayiotou, A.3
Palmen, J.4
Cooper, J.A.5
Ricketts, S.L.6
-
81
-
-
84888256840
-
Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study
-
Holmes MV, Simon T, Exeter HJ et al. Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol 2013;62:1966-76.
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. 1966-1976
-
-
Holmes, M.V.1
Simon, T.2
Exeter, H.J.3
-
82
-
-
84871771750
-
Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis
-
Stender S, Frikke-Schmidt R, Nordestgaard BG, Grande P, Tybjaerg-Hansen A. Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis. J Intern Med 2013;273:59-68.
-
(2013)
J Intern Med
, vol.273
, pp. 59-68
-
-
Stender, S.1
Frikke-Schmidt, R.2
Nordestgaard, B.G.3
Grande, P.4
Tybjaerg-Hansen, A.5
-
83
-
-
84881442965
-
Association of plasma uric acid with ischaemic heart disease and blood pressure: Mendelian randomisation analysis of two large cohorts
-
Palmer TM, Nordestgaard BG, Benn M et al. Association of plasma uric acid with ischaemic heart disease and blood pressure: Mendelian randomisation analysis of two large cohorts. BMJ 2013;347:f4262.
-
(2013)
BMJ
, vol.347
-
-
Palmer, T.M.1
Nordestgaard, B.G.2
Benn, M.3
-
84
-
-
28244453652
-
Nature's randomised trials
-
Hingorani A, Humphries S. Nature's randomised trials. Lancet 2005;366:1906-08.
-
(2005)
Lancet
, vol.366
, pp. 1906-1908
-
-
Hingorani, A.1
Humphries, S.2
-
85
-
-
84930650718
-
Mendelian randomisation applied to drug development in cardiovascular disease: a review
-
Mokry JE, Ahmad O, Forgetta V, Thanassoulis G, Richards JB. Mendelian randomisation applied to drug development in cardiovascular disease: a review. J Med Genet 2015;52: 71-79.
-
(2015)
J Med Genet
, vol.52
, pp. 71-79
-
-
Mokry, J.E.1
Ahmad, O.2
Forgetta, V.3
Thanassoulis, G.4
Richards, J.B.5
-
86
-
-
55249087635
-
Genetically elevated C-reactive protein and ischemic vascular disease
-
Zacho J, Tybjaerg A, Jensen JS, Grande P, Sillesen H, Nordestgaard BG. Genetically elevated C-reactive protein and ischemic vascular disease. N Engl J Med 2008;359: 1897-908.
-
(2008)
N Engl J Med
, vol.359
, pp. 1897-1908
-
-
Zacho, J.1
Tybjaerg, A.2
Jensen, J.S.3
Grande, P.4
Sillesen, H.5
Nordestgaard, B.G.6
-
87
-
-
84859215358
-
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis
-
Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium. The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet 2012;379:1214-24.
-
(2012)
Lancet
, vol.379
, pp. 1214-1224
-
-
-
88
-
-
84859210770
-
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
-
IL6R Genetics Consortium. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet 2012;379:1205-13.
-
(2012)
Lancet
, vol.379
, pp. 1205-1213
-
-
-
89
-
-
84904543855
-
Anti-inflammatory therapies for cardiovascular disease
-
Ridker PM, Lüscher TF. Anti-inflammatory therapies for cardiovascular disease. Eur Heart J 2014;35:1782-91.
-
(2014)
Eur Heart J
, vol.35
, pp. 1782-1791
-
-
Ridker, P.M.1
Lüscher, T.F.2
-
90
-
-
84921493092
-
HMGcoenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
-
Swerdlow DI, Preiss D, Kuchenbaecker KB et al. HMGcoenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet 2015;385:351-61.
-
(2015)
Lancet
, vol.385
, pp. 351-361
-
-
Swerdlow, D.I.1
Preiss, D.2
Kuchenbaecker, K.B.3
-
91
-
-
84921456550
-
Statins and type 2 diabetes: genetic studies on target
-
Frayling TM. Statins and type 2 diabetes: genetic studies on target. Lancet 2015;385:310-12.
-
(2015)
Lancet
, vol.385
, pp. 310-312
-
-
Frayling, T.M.1
-
92
-
-
84870045994
-
Effects of dalcetrapib in patients with a recent acute coronary syndrome
-
Schwartz GG, Olsson AG, Abt M et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med 2012;367:2089-99.
-
(2012)
N Engl J Med
, vol.367
, pp. 2089-2099
-
-
Schwartz, G.G.1
Olsson, A.G.2
Abt, M.3
-
93
-
-
34447265547
-
Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial
-
Bots ML, Visseren FL, Evans GW et al. Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial. Lancet 2007;370: 153-60.
-
(2007)
Lancet
, vol.370
, pp. 153-160
-
-
Bots, M.L.1
Visseren, F.L.2
Evans, G.W.3
-
94
-
-
74549185752
-
Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms
-
Sofat R, Hingorani AD, Smeeth L et al. Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. Circulation 2010;121:52-62.
-
(2010)
Circulation
, vol.121
, pp. 52-62
-
-
Sofat, R.1
Hingorani, A.D.2
Smeeth, L.3
-
95
-
-
84925298675
-
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis
-
Freitag DF, Butterworth AS, Willeit P et al. for the Interleukin 1 Genetics Consortium. Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis. Lancet Diabet Endocrinol 2015;3: 243-53.
-
(2015)
Lancet Diabet Endocrinol
, vol.3
, pp. 243-253
-
-
Freitag, D.F.1
Butterworth, A.S.2
Willeit, P.3
-
96
-
-
84893735878
-
Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis
-
Holmes MV, Lange LA, Palmer T, Lanktree MB, North KE, Almoguera B. Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis. Am J Hum Genet 2014;94:198-208.
-
(2014)
Am J Hum Genet
, vol.94
, pp. 198-208
-
-
Holmes, M.V.1
Lange, L.A.2
Palmer, T.3
Lanktree, M.B.4
North, K.E.5
Almoguera, B.6
-
97
-
-
84928021248
-
Genetically determined height and coronary artery disease
-
Nelson CP, Hamby SE, Saleheen D et al. Genetically determined height and coronary artery disease. N Engl J Med 2015; 372:1608-61.
-
(2015)
N Engl J Med
, vol.372
, pp. 1608-1661
-
-
Nelson, C.P.1
Hamby, S.E.2
Saleheen, D.3
-
98
-
-
84856718639
-
Credible Mendelian randomization studies: approaches for evaluating the instrumental variable assumptions
-
Glymour MM, Tchetgen Tchetgen EJ, Robins JM. Credible Mendelian randomization studies: approaches for evaluating the instrumental variable assumptions. Am J Epidemiol 2012; 175:332-39.
-
(2012)
Am J Epidemiol
, vol.175
, pp. 332-339
-
-
Glymour, M.M.1
Tchetgen Tchetgen, E.J.2
Robins, J.M.3
-
99
-
-
84879271608
-
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
-
Rietveld CA, Medland SE, Derringer J et al. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science 2013;340:1467-71.
-
(2013)
Science
, vol.340
, pp. 1467-1471
-
-
Rietveld, C.A.1
Medland, S.E.2
Derringer, J.3
-
100
-
-
84904480118
-
Genetic variation associated with differential educational attainment in adults has anticipated associations with school performance in children
-
Ward ME, McMahon G, St Pourcain B et al. Genetic variation associated with differential educational attainment in adults has anticipated associations with school performance in children. PLoS One 2014;9:e100248.
-
(2014)
PLoS One
, vol.9
-
-
Ward, M.E.1
McMahon, G.2
St Pourcain, B.3
-
101
-
-
84887297875
-
Mining the human phenome using allelic scores that index biological intermediates
-
Evans DM, Brion MJ, Paternoster L et al. Mining the human phenome using allelic scores that index biological intermediates. PLoS Genet 2013;9:e1003919.
-
(2013)
PLoS Genet
, vol.9
-
-
Evans, D.M.1
Brion, M.J.2
Paternoster, L.3
-
102
-
-
84946580333
-
An atlas of genetic correlations across human diseases and traits
-
Bulik-Sullivan B, Finucane HK, Anttila V et al. An atlas of genetic correlations across human diseases and traits. Bioarxiv 2015. doi: http://dx.doi.org/10.1101/014498.
-
(2015)
Bioarxiv
-
-
Bulik-Sullivan, B.1
Finucane, H.K.2
Anttila, V.3
-
103
-
-
84936745507
-
Mendelian randomisation studies: a review of the approaches used and the quality of reporting
-
Boef AGD, Dekkers OM, le Cessie S. Mendelian randomisation studies: a review of the approaches used and the quality of reporting. Int J Epidemiol 2015;44:496-511.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 496-511
-
-
Boef, A.G.D.1
Dekkers, O.M.2
le Cessie, S.3
-
104
-
-
84936753148
-
High tobacco consumption lowers body weight: a Mendelian randomization study of the Copenhagen General Population study
-
Winsløw UC, Rode L, Nordestgaard B. High tobacco consumption lowers body weight: a Mendelian randomization study of the Copenhagen General Population study. Int J Epidemiol 2015;44:540-50.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 540-550
-
-
Winsløw, U.C.1
Rode, L.2
Nordestgaard, B.3
-
105
-
-
84936773598
-
Coffee intake and risk of obesity, metabolic syndrome and type 2 diabetes: a Mendelian randomization study
-
Nordestgaard AT, Thomsen M, Nordestgaard BG. Coffee intake and risk of obesity, metabolic syndrome and type 2 diabetes: a Mendelian randomization study. Int J Epidemiol 2015; 44:551-65.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 551-565
-
-
Nordestgaard, A.T.1
Thomsen, M.2
Nordestgaard, B.G.3
-
106
-
-
84936757019
-
Milk intake is not associated with ischemic heart disease in observational of Mendelian randomization analyses in 98 529 Danish adults
-
Bergholdt HKM, Nordestgaard BG, Varbo A, Ellervik C. Milk intake is not associated with ischemic heart disease in observational of Mendelian randomization analyses in 98 529 Danish adults. Int J Epidemiol 2015;44: 587-603.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 587-603
-
-
Bergholdt, H.K.M.1
Nordestgaard, B.G.2
Varbo, A.3
Ellervik, C.4
-
107
-
-
84936773291
-
Increased alcohol consumption as a cause of alcoholism, without similar evidence for depression: A Mendelian randomization study
-
Wium-Andersen MK, Ørsted DD, Schurmann Tolstrup J, Nordestgaard BG. Increased alcohol consumption as a cause of alcoholism, without similar evidence for depression: A Mendelian randomization study. Int J Epidemiol 2015;44: 526-39.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 526-539
-
-
Wium-Andersen, M.K.1
Ørsted, D.D.2
Schurmann Tolstrup, J.3
Nordestgaard, B.G.4
-
108
-
-
84936753519
-
Adiposity as a cause of cardiovascular disease: a Mendelian randomization study
-
Hägg S, Fall T, Ploner A et al. Adiposity as a cause of cardiovascular disease: a Mendelian randomization study. Int J Epidemiol 2015;44:578-86.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 578-586
-
-
Hägg, S.1
Fall, T.2
Ploner, A.3
-
109
-
-
84936754004
-
Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian 5 randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium
-
Sungin D, Cornelis MC, Divaris K et al. Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian 5 randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium. Int J Epidemiol 2015;44:638-50.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 638-650
-
-
Sungin, D.1
Cornelis, M.C.2
Divaris, K.3
-
110
-
-
84936750128
-
No evidence that genetically reduced 25-hydroxyvitamin D is associated with increased risk of ischemic heart disease or myocardial infarction. A Mendelian randomization study
-
Brøndum-Jacobsen P, Benn M, Afzal S, Nordestgaard BG. No evidence that genetically reduced 25-hydroxyvitamin D is associated with increased risk of ischemic heart disease or myocardial infarction. A Mendelian randomization study. Int J Epidemiol 2015;44:651-61.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 651-661
-
-
Brøndum-Jacobsen, P.1
Benn, M.2
Afzal, S.3
Nordestgaard, B.G.4
-
111
-
-
84936764512
-
Genetically predicted testosterone and electrocardiographic QT interval duration in Chinese: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study
-
Zhao J, Jiang, C, Lam TH, Liu B, Cheng KK, Xu L. Genetically predicted testosterone and electrocardiographic QT interval duration in Chinese: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study. Int J Epidemiol 2015;44: 613-20.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 613-620
-
-
Zhao, J.1
Jiang, C.2
Lam, T.H.3
Liu, B.4
Cheng, K.K.5
Xu, L.6
-
112
-
-
84936750878
-
Commentary: Mendelian randomization, testosterone, and cardiovascular disease
-
Gong J, Zubair N. Commentary: Mendelian randomization, testosterone, and cardiovascular disease. Int J Epidemiol 2015; 44:621-22.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 621-622
-
-
Gong, J.1
Zubair, N.2
-
113
-
-
33645084282
-
Limits to causal inference based on mendelian randomization: a comparison with randomized controlled trials
-
Nitsch D, Molokhia M, Smeeth L, DeStavola BL, Whittaker JC, Leon DA. Limits to causal inference based on mendelian randomization: a comparison with randomized controlled trials. Am J Epidemiol 2006;163:397-403.
-
(2006)
Am J Epidemiol
, vol.163
, pp. 397-403
-
-
Nitsch, D.1
Molokhia, M.2
Smeeth, L.3
DeStavola, B.L.4
Whittaker, J.C.5
Leon, D.A.6
-
114
-
-
50949084462
-
Mendelian randomisation and causal inference in observational epidemiology
-
Sheehan NA, Didelez V, Burton PR, Tobin MD. Mendelian randomisation and causal inference in observational epidemiology. PLoS Med 2008;5:e177.
-
(2008)
PLoS Med
, vol.5
-
-
Sheehan, N.A.1
Didelez, V.2
Burton, P.R.3
Tobin, M.D.4
-
115
-
-
84856718639
-
Credible Mendelian randomization studies: approaches for evaluating the instrumental variable assumptions
-
Glymour MM, Tchetgen EJ, Robins JM. Credible Mendelian randomization studies: approaches for evaluating the instrumental variable assumptions. Am J Epidemiol 2012; 175:332-39.
-
(2012)
Am J Epidemiol
, vol.175
, pp. 332-339
-
-
Glymour, M.M.1
Tchetgen, E.J.2
Robins, J.M.3
-
117
-
-
84884736257
-
Use of allele scores as instrumental variables for Mendelian randomization
-
Burgess S, Thompson SG. Use of allele scores as instrumental variables for Mendelian randomization. Int J Epidemiol 2013; 42:1134-44.
-
(2013)
Int J Epidemiol
, vol.42
, pp. 1134-1144
-
-
Burgess, S.1
Thompson, S.G.2
-
118
-
-
84898967273
-
Assessing causality in the association between child adiposity and physical activity levels: A Mendelian randomization analysis
-
Richmond RC, Davey Smith G, Ness AR, den Hoed M, MacMahon G, Timpson NJ. Assessing causality in the association between child adiposity and physical activity levels: A Mendelian randomization analysis. PLoS Med 2014;11: e1001618.
-
(2014)
PLoS Med
, vol.11
-
-
Richmond, R.C.1
Davey Smith, G.2
Ness, A.R.3
den Hoed, M.4
MacMahon, G.5
Timpson, N.J.6
|