-
1
-
-
17744376022
-
Anti-immunoglobulin e treatment with omalizumab in allergic diseases: An update on anti-inflammatory activity and clinical efficacy
-
Holgate, S. T., Djukanovic, R., Casale, T. & Bousquet, J. Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy. Clin. Exp. Allergy 35, 408-416 (2005).
-
(2005)
Clin. Exp. Allergy
, vol.35
, pp. 408-416
-
-
Holgate, S.T.1
Djukanovic, R.2
Casale, T.3
Bousquet, J.4
-
2
-
-
79952795093
-
Randomized trial of omalizumab (anti-IgE) for asthma in innercity children
-
Busse, W. W. et al. Randomized trial of omalizumab (anti-IgE) for asthma in innercity children. N. Engl. J. Med. 364, 1005-1015 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 1005-1015
-
-
Busse, W.W.1
-
3
-
-
50849120030
-
Genome-wide scan on total serumIgE levels identifies FCER1A as novel susceptibility locus
-
Weidinger, S. et al. Genome-wide scan on total serumIgE levels identifies FCER1A as novel susceptibility locus. PLoS Genet. 4, e1000166 (2008).
-
(2008)
PLoS Genet.
, vol.4
, pp. e1000166
-
-
Weidinger, S.1
-
4
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
Moffatt, M. F. et al. A large-scale, consortium-based genomewide association study of asthma. N. Engl. J. Med. 363, 1211-1221 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1211-1221
-
-
Moffatt, M.F.1
-
5
-
-
84875733039
-
A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations
-
Levin, A. M. et al. A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. J. Allergy Clin. Immunol. 131, 1176-1184 (2013).
-
(2013)
J. Allergy Clin. Immunol.
, vol.131
, pp. 1176-1184
-
-
Levin, A.M.1
-
6
-
-
84857800654
-
A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study
-
Granada, M. et al. A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study. J. Allergy Clin. Immunol. 129, 840-845 (2012).
-
(2012)
J. Allergy Clin. Immunol.
, vol.129
, pp. 840-845
-
-
Granada, M.1
-
7
-
-
0034533729
-
Cytokine expression during allergen-induced late nasal responses: IL-4 and IL-5 mRNA is expressed early (at 6 h) predominantly by eosinophils
-
Nouri-Aria, K. T. et al. Cytokine expression during allergen-induced late nasal responses: IL-4 and IL-5 mRNA is expressed early (at 6 h) predominantly by eosinophils. Clin. Exp. Allergy 30, 1709-1716 (2000).
-
(2000)
Clin. Exp. Allergy
, vol.30
, pp. 1709-1716
-
-
Nouri-Aria, K.T.1
-
8
-
-
79959872458
-
Cell type-specific DNA methylation at intragenic CpG islands in the immune system
-
Deaton, A. M. et al. Cell type-specific DNA methylation at intragenic CpG islands in the immune system. Genome Res. 21, 1074-1086 (2011).
-
(2011)
Genome Res.
, vol.21
, pp. 1074-1086
-
-
Deaton, A.M.1
-
9
-
-
33751505540
-
DNAmethylation profiling of humanchromosomes6 20 and 22
-
Eckhardt, F. et al. DNAmethylation profiling of humanchromosomes6, 20 and 22. Nature Genet. 38, 1378-1385 (2006).
-
(2006)
Nature Genet
, vol.38
, pp. 1378-1385
-
-
Eckhardt, F.1
-
10
-
-
0036017401
-
Cytokinememory of T helper lymphocytes
-
Löhning, M., Richter, A. & Radbruch, A. Cytokinememory of T helper lymphocytes. Adv. Immunol. 80, 115-181 (2002).
-
(2002)
Adv. Immunol.
, vol.80
, pp. 115-181
-
-
Löhning, M.1
Richter, A.2
Radbruch, A.3
-
11
-
-
84862157386
-
Quantitative cross-validation and content analysis of the 450k DNA methylation array from Illumina Inc
-
Roessler, J. et al. Quantitative cross-validation and content analysis of the 450k DNA methylation array from Illumina, Inc. BMC Res. Notes 5, 210 (2012).
-
(2012)
BMC Res. Notes
, vol.5
, pp. 210
-
-
Roessler, J.1
-
12
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
Moffatt, M. F. et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448, 470-473 (2007).
-
(2007)
Nature
, vol.448
, pp. 470-473
-
-
Moffatt, M.F.1
-
13
-
-
84879808085
-
Interactive effect of STAT6 and IL13 gene polymorphisms on eczema status: Results froma longitudinal and a cross-sectional study
-
Ziyab, A. H. et al. Interactive effect of STAT6 and IL13 gene polymorphisms on eczema status: results froma longitudinal and a cross-sectional study. BMC Med. Genet. 14, 67 (2013).
-
(2013)
BMC Med. Genet.
, vol.14
, pp. 67
-
-
Ziyab, A.H.1
-
14
-
-
84902083497
-
The Saguenay-Lac-Saint-Jean asthma familial collection: The genetics of asthma in a young founder population
-
Laprise, C. The Saguenay-Lac-Saint-Jean asthma familial collection: the genetics of asthma in a young founder population. Genes Immun. 15, 247-255 (2014).
-
(2014)
Genes Immun
, vol.15
, pp. 247-255
-
-
Laprise, C.1
-
15
-
-
0034046480
-
Independent inheritance of serum immunoglobulin e concentrations and airway responsiveness
-
Palmer, L. J. et al. Independent inheritance of serum immunoglobulin E concentrations and airway responsiveness. Am. J. Respir. Crit. Care Med. 161, 1836-1843 (2000).
-
(2000)
Am. J. Respir. Crit. Care Med.
, vol.161
, pp. 1836-1843
-
-
Palmer, L.J.1
-
16
-
-
23344453342
-
A critical control element for interleukin-4 memory expression in T helper lymphocytes
-
Tykocinski, L. O. et al. A critical control element for interleukin-4 memory expression in T helper lymphocytes. J. Biol. Chem. 280, 28177-28185 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28177-28185
-
-
Tykocinski, L.O.1
-
17
-
-
33646196946
-
RegulationofTh2differentiation and Il4 locus accessibility
-
Ansel, K. M., Djuretic, I., Tanasa, B.&Rao, A. RegulationofTh2differentiation and Il4 locus accessibility. Annu. Rev. Immunol. 24, 607-656 (2006).
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 607-656
-
-
Ansel, K.M.1
Djuretic, I.2
Tanasa, B.3
Rao, A.4
-
18
-
-
84858648623
-
Two-step epigenetic Mendelian randomization: A strategy for establishing the causal role of epigenetic processes in pathways to disease
-
Relton, C. L. & Davey Smith, G. Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease. Int. J. Epidemiol. 41, 161-176 (2012).
-
(2012)
Int. J. Epidemiol.
, vol.41
, pp. 161-176
-
-
Relton, C.L.1
Davey Smith, G.2
-
19
-
-
0023879839
-
Recombinant human interleukin 5 is a selective activator of human eosinophil function
-
Lopez, A. F. et al. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J. Exp. Med. 167, 219-224 (1988).
-
(1988)
J. Exp. Med.
, vol.167
, pp. 219-224
-
-
Lopez, A.F.1
-
20
-
-
79959353756
-
Eosinophils: Multifaceted biological properties and roles in health and disease
-
Kita, H. Eosinophils: multifaceted biological properties and roles in health and disease. Immunol. Rev. 242, 161-177 (2011).
-
(2011)
Immunol. Rev.
, vol.242
, pp. 161-177
-
-
Kita, H.1
-
21
-
-
84864359044
-
Differential DNA methylation in purified human blood cells: Implications for cell lineage and studies on disease susceptibility
-
Reinius, L. E. et al. Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility. PLoS ONE 7, e41361 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e41361
-
-
Reinius, L.E.1
-
22
-
-
38549139719
-
Regulation of immunological homeostasis in the respiratory tract
-
Holt, P. G., Strickland, D. H., Wikstrom, M. E. & Jahnsen, F. L. Regulation of immunological homeostasis in the respiratory tract. Nature Rev. Immunol. 8, 142-152 (2008).
-
(2008)
Nature Rev. Immunol.
, vol.8
, pp. 142-152
-
-
Holt, P.G.1
Strickland, D.H.2
Wikstrom, M.E.3
Jahnsen, F.L.4
-
23
-
-
84860637797
-
DNA methylation arrays as surrogate measures of cell mixture distribution
-
Houseman, E. A. et al. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics 13, 86 (2012).
-
(2012)
BMC Bioinformatics
, vol.13
, pp. 86
-
-
Houseman, E.A.1
-
24
-
-
34250343830
-
A single enzyme catalyzes both platelet-activating factor production and membrane biogenesis of inflammatory cells. Cloning and characterization of acetyl-CoA:LYSO-PAF acetyltransferase
-
Shindou, H. et al. A single enzyme catalyzes both platelet-activating factor production and membrane biogenesis of inflammatory cells. Cloning and characterization of acetyl-CoA:LYSO-PAF acetyltransferase. J. Biol. Chem. 282, 6532-6539 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 6532-6539
-
-
Shindou, H.1
-
25
-
-
0033941665
-
The Ile198Thr and Ala379Val variants of plasmatic PAFacetylhydrolase impair catalytical activities and are associated with atopy and asthma
-
Kruse, S. et al. The Ile198Thr and Ala379Val variants of plasmatic PAFacetylhydrolase impair catalytical activities and are associated with atopy and asthma. Am. J. Hum. Genet. 66, 1522-1530 (2000).
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 1522-1530
-
-
Kruse, S.1
-
26
-
-
0035852636
-
Mitochondria in eosinophils: Functional role inapoptosisbut not respiration
-
Peachman, K. K., Lyles, D. S. & Bass, D. A. Mitochondria in eosinophils: functional role inapoptosisbut not respiration. Proc. NatlAcad. Sci. USA98, 1717-1722(2001).
-
(2001)
Proc. NatlAcad. Sci. USA
, vol.98
, pp. 1717-1722
-
-
Peachman, K.K.1
Lyles, D.S.2
Bass, D.A.3
-
27
-
-
78751627318
-
Eosinophils are required for the maintenance of plasma cells in the bone marrow
-
Chu, V. T. et al. Eosinophils are required for the maintenance of plasma cells in the bone marrow. Nature Immunol. 12, 151-159 (2011).
-
(2011)
Nature Immunol.
, vol.12
, pp. 151-159
-
-
Chu, V.T.1
-
28
-
-
84865145614
-
Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
-
Pavord, I. D. et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet 380, 651-659 (2012).
-
(2012)
Lancet
, vol.380
, pp. 651-659
-
-
Pavord, I.D.1
-
29
-
-
79953706343
-
Tobacco-smokingrelated differential DNA methylation: 27K discovery and replication
-
Breitling, L. P., Yang, R., Korn, B., Burwinkel, B. & Brenner, H. Tobacco-smokingrelated differential DNA methylation: 27K discovery and replication. Am. J. Hum. Genet. 88, 450-457 (2011).
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 450-457
-
-
Breitling, L.P.1
Yang, R.2
Korn, B.3
Burwinkel, B.4
Brenner, H.5
-
30
-
-
84863509978
-
Cigarette smoking behaviors and timesince quitting are associated with differentialDNA methylation across the human genome
-
Wan, E. S. et al. Cigarette smoking behaviors and timesince quitting are associated with differentialDNA methylation across the human genome. Hum. Mol. Genet. 21, 3073-3082 (2012).
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 3073-3082
-
-
Wan, E.S.1
-
31
-
-
84862266444
-
Complete pipeline for Infinium((R)) Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation
-
Touleimat, N. & Tost, J. Complete pipeline for Infinium((R)) Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation. Epigenomics 4, 325-341 (2012).
-
(2012)
Epigenomics
, vol.4
, pp. 325-341
-
-
Touleimat, N.1
Tost, J.2
-
32
-
-
46249088370
-
Lumi: Apipeline for processingIlluminamicroarray
-
Du, P., Kibbe, W. A.&Lin, S. M. lumi: apipeline for processingIlluminamicroarray. Bioinformatics 24, 1547-1548 (2008).
-
(2008)
Bioinformatics
, vol.24
, pp. 1547-1548
-
-
Du, P.1
Kibbe, W.A.2
Lin, S.M.3
-
33
-
-
0035017590
-
Eotaxin promotes eosinophil transmigration via the activation of the plasminogen-plasmin system
-
Ferland, C. et al. Eotaxin promotes eosinophil transmigration via the activation of the plasminogen-plasmin system. J. Leukoc. Biol. 69, 772-778 (2001).
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 772-778
-
-
Ferland, C.1
-
34
-
-
77955894071
-
METAL: Fast and efficient meta-analysis of genomewide association scans
-
Willer, C. J., Li, Y. & Abecasis, G. R. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics 26, 2190-2191 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 2190-2191
-
-
Willer, C.J.1
Li, Y.2
Abecasis, G.R.3
-
35
-
-
84864417548
-
Fast and accurate genotype imputation in genome-wide association studies through prephasing
-
Howie, B., Fuchsberger, C., Stephens, M., Marchini, J. & Abecasis, G. R. Fast and accurate genotype imputation in genome-wide association studies through prephasing. Nature Genet. 44, 955-959 (2012).
-
(2012)
Nature Genet.
, vol.44
, pp. 955-959
-
-
Howie, B.1
Fuchsberger, C.2
Stephens, M.3
Marchini, J.4
Abecasis, G.R.5
-
36
-
-
40849083720
-
Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
-
Lawlor, D. A., Harbord, R. M., Sterne, J. A., Timpson, N. & Davey Smith, G. Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat. Med. 27, 1133-1163 (2008).
-
(2008)
Stat. Med.
, vol.27
, pp. 1133-1163
-
-
Lawlor, D.A.1
Harbord, R.M.2
Sterne, J.A.3
Timpson, N.4
Davey Smith, G.5
|