HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials

The Lancet

Volumn 385, Issue 9965, 2015, Pages 351-361

  Swerdlow, Daniel I ^a   Preiss, David ^c   Kuchenbaecker, Karoline B ^f,g,h   Holmes, Michael V ^a   Engmann, Jorgen E L ^a   Shah, Tina ^a   Sofat, Reecha ^b   Stender, Stefan ⁱ   Johnson, Paul C D ^d   Scott, Robert A ^j   Leusink, Maarten ^k   Verweij, Niek ^l   Sharp, Stephen J ^j   Guo, Yiran ^m   Giambartolomei, Claudia ^a   Chung, Christina ^a   Peasey, Anne ^a   Amuzu, Antoinette ^o   Li, Kawah ^m   Palmen, Jutta ^a   Howard, Philip ^a   Cooper, Jackie A ^a   Drenos, Fotios ^a   Li, Yun R ^a   Lowe, Gordon ^d   Gallacher, John ^p   Stewart, Marlene C W ^p   Tzoulaki, Ioanna ^q   Buxbaum, Sarah G ^s   Van Der A, Daphne L ^s   Forouhi, Nita G ^j   Onland Moret, N Charlotte ^s   Van Der Schouw, Yvonne T ^s   Schnabel, Renate B ^w,x   Hubacek, Jaroslav A ^y   Kubinova, Ruzena ^z   Baceviciene, Migle ^ab   Tamosiunas, Abdonas ^aa   Pajak, Andrzej ^ac   Topor Madry, Romanvan ^ac   Stepaniak, Urszula ^ac   Malyutina, Sofia ^ac   Baldassarre, Damiano ^ad,ae,ai   Sennblad, Bengt ^af   Tremoli, Elena ^ad,ae,ai   De Faire, Ulf ^ag   Veglia, Fabrizio ^ah   Ford, Ian ^d   Jukema, J Wouter ^aj   Westendorp, Rudi G J ^aj   De Borst, Gert Jan ^s   De Jong, Pim A ^s   Algra, Ale ^s,t   Spiering, Wilko ^u   Der Zee, Anke H Maitland Van ^k   Klungel, Olaf H ^k   De Boer, Anthonius ^k   Doevendans, Pieter A ^v   Eaton, Charles B ^ak   Robinson, Jennifer G ^al   Duggan, David ^am   Kjekshus, John ^an   Downs, John R ^l,ap,aq   Gotto, Antonio M ^ar   Keech, Anthony C ^as   Marchioli, Roberto ^at   Tognoni, Gianni ^au   Sever, Peter S ^r   Poulter, Neil R ^r   Waters, David D ^av   Pedersen, Terje R ^ao   Amarenco, Pierre ^aw   Nakamura, Haruo ^ax   McMurray, John J V ^c,d   Lewsey, James D ^e   Chasman, Daniel I ^ay   Ridker, Paul M ^ay   Maggioni, Aldo P ^ba   Tavazzi, Luigi ^bb   Ray, Kausik K ^bc   Seshasai, Sreenivasa Rao Kondapally ^bc   Manson, Joann E ^ay   Price, Jackie F ^p   Whincup, Peter H ^bd   Morris, Richard W ^a   Lawlor, Debbie A ^be,bf   Smith, George Davey ^be,bf   Ben Shlomo, Yoav ^bf   Schreiner, Pamela J ^bg   Fornage, Myriam ^bi   Siscovick, David S ^bj   Cushman, Mary ^bl,bm   Kumari, Meena ^a   Wareham, Nick J ^j   Verschuren, W M Monique ^s   Redline, Susan ^az   Patel, Sanjay R ^az   Whittaker, John C ^bg   Hamsten, Anders ^af   Delaney, Joseph A ^bk   Dale, Caroline ⁿ   Gaunt, Tom R ^be   Wong, Andrew ^a   Kuh, Diana ^a   Hardy, Rebecca ^a   Kathiresan, Sekar ^bn   Castillo, Berta A ^m   Van Der Harst, Pim ^l   Brunner, Eric J ^a   Tybjaerg Hansen, Anne ⁱ   Marmot, Michael G ^a   Krauss, Ronald M ^bo   Tsai, Michael ^bh   Coresh, Josef ^bp   Hoogeveen, Ronald C ^bp   Psaty, Bruce M ^bj   Lange, Leslie A ^bp   Hakonarson, Hakon ^m   Dudbridge, Frank ^o   Humphries, Steve E ^a   Talmud, Philippa J ^a   Kivimäki, Mika ^b   Timpson, Nicholas J ^be,bf   Langenberg, Claudia ^j   Asselbergs, Folkert W ^a,v   Voevoda, Mikhail ^ac   Bobak, Martin ^a   Pikhart, Hynek ^a   Wilson, James G ^bp   Reiner, Alex P ^bp   Keating, Brendan J ^m   Hingorani, Aroon D ^a   Sattar, Naveed ^c,d   more..

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g Rigshospitalet   (Denmark)

^h UNIVERSITY OF CAMBRIDGE   (United Kingdom)

ⁱ UTRECHT UNIVERSITY   (Netherlands)

^j UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^k CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^l Cardiff University ^*  (Italy)

^m LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

ⁿ CARDIFF UNIVERSITY   (United Kingdom)

^o UNIVERSITY OF EDINBURGH   (United Kingdom)

^p IMPERIAL COLLEGE LONDON   (United Kingdom)

^q JACKSON STATE UNIVERSITY   (United States)

^r NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^s UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^t UNIVERSITY HEART CENTER HAMBURG   (Germany)

^u INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^v NATIONAL INSTITUTE OF PUBLIC HEALTH   (Czech Republic)

^w Institute of Cardiology   (Lithuania)

^x LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

^y JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^z INSTITUTE OF PHYSIOLOGY   (Russian Federation)

^aa INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^ab UNIVERSITY OF MILAN   (Italy)

^ac KAROLINSKA INSTITUTE   (Sweden)

^ad Policlinico Polispecialistico Multimedica   (Italy)

^ae CENTRO CARDIOLOGICO MONZINO   (Italy)

^af LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^ag MEMORIAL HOSPITAL OF RHODE ISLAND   (United States)

^ah UNIVERSITY OF IOWA   (United States)

^ai TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^aj OSLO UNIVERSITY HOSPITAL   (Norway)

^ak UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^al SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^am WEILL CORNELL MEDICAL COLLEGE   (United States)

^an UNIVERSITY OF SYDNEY   (Australia)

^ao IQVIA   (United States)

^ap UNIVERSITY OF CALIFORNIA   (United States)

^aq UNIVERSITÉ PARIS DESCARTES   (France)

^ar Mitsukoshi Health and Welfare Foundation   (Japan)

^as Division of Preventive Medicine   (United States)

^at Division of Sleep Medicine   (United States)

^au HARVARD MEDICAL SCHOOL   (United States)

^av ANMCO RESEARCH CENTER   (Italy)

^aw MARIA CECILIA HOSPITAL   (Italy)

^ax Centre for Adult and Paediatric Gastroenterology   (United Kingdom)

^ay ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^az UNIVERSITY OF BRISTOL   (United Kingdom)

^ba UNIVERSITY OF MINNESOTA   (United States)

^bb UNIVERSITY OF MINNESOTA   (United States)

^bc UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^bd UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^be UNIVERSITY OF WASHINGTON   (United States)

^bf UNIVERSITY OF VERMONT   (United States)

^bg GLAXOSMITHKLINE   (United Kingdom)

^bh MASSACHUSETTS GENERAL HOSPITAL   (United States)

^bi BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^bj CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^bk JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^bl BAYLOR COLLEGE OF MEDICINE   (United States)

^bm UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^bn ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^bo UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^bp Fred Hutchinson Cancer Research Center   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HMGCR PROTEIN, HUMAN;

ALLELE; ARTICLE; BODY WEIGHT; DIET RESTRICTION; ENZYME INHIBITION; FOLLOW UP; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ANALYSIS; GENETIC ASSOCIATION; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; META ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE NUCLEOTIDE POLYMORPHISM; WAIST CIRCUMFERENCE; AGED; BODY MASS; FEMALE; GENETIC SCREENING; GENETICS; MALE; METABOLISM; MIDDLE AGED; RISK FACTOR;

AGED; BODY MASS INDEX; BODY WEIGHT; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC TESTING; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS;

EID: 84921493092     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(14)61183-1     Document Type: Article

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