Mendelian randomization analysis with multiple genetic variants using summarized data

Genetic Epidemiology

Volumn 37, Issue 7, 2013, Pages 658-665

  Burgess, Stephen ^a   Butterworth, Adam ^a   Thompson, Simon G ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Causal inference; Genome wide association study; Instrumental variables; Mendelian randomization; Weak instruments

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ALLELE; ARTICLE; CHROMOSOME 1; CHROMOSOME 19; CHROMOSOME 2; CHROMOSOME 5; CORONARY ARTERY DISEASE; CORONARY RISK; GENE INTERACTION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC MODEL; GENETIC VARIABILITY; HUMAN; MENDELIAN RANDOMIZATION ANALYSIS; OUTCOME ASSESSMENT; PLEIOTROPY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL;

CAUSAL INFERENCE; GENOME-WIDE ASSOCIATION STUDY; INSTRUMENTAL VARIABLES; MENDELIAN RANDOMIZATION; WEAK INSTRUMENTS;

BIAS (EPIDEMIOLOGY); CHOLESTEROL, LDL; CORONARY DISEASE; GENES; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LEAST-SQUARES ANALYSIS; LIKELIHOOD FUNCTIONS; LINEAR MODELS; LINKAGE DISEQUILIBRIUM; MENDELIAN RANDOMIZATION ANALYSIS; MODELS, GENETIC; ODDS RATIO; PHENOTYPE; RISK FACTORS;

EID: 84885840876     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.21758     Document Type: Article

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