Alcohol consumption, genetic variants in alcohol deydrogenases, and risk of cardiovascular diseases: A prospective study and meta-analysis

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Drogan, Dagmar ^a   Sheldrick, Abigail J ^b,d   Schütze, Madlen ^a   Knüppel, Sven ^a   Andersohn, Frank ^b   Giuseppe, Romina ^a   Herrmann, Bianca ^a,e   Willich, Stefan N ^b   Garbe, Edeltraut ^c   Bergmann, Manuela M ^a   Boeing, Heiner ^a   Weikert, Cornelia ^a,b  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c LEIBNIZ INSTITUTE FOR PREVENTION RESEARCH AND EPIDEMIOLOGY BIPS   (Germany)

^d RWTH AACHEN UNIVERSITY   (Germany)

^e BAM FEDERAL INSTITUTE FOR MATERIALS RESEARCH AND TESTING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; ADH1B PROTEIN, HUMAN; ADH1C PROTEIN, HUMAN;

ADULT; ALCOHOL CONSUMPTION; ALCOHOL DEHYDROGENASE 1B GENE; ALCOHOL DEHYDROGENASE 1C GENE; ALCOHOL OXIDATION; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CASE STUDY; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GENE; GENETIC ANALYSIS; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GENOTYPE; GERMANY; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; RISK REDUCTION; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; STROKE; AGED; CONFIDENCE INTERVAL; DRINKING BEHAVIOR; ENZYMOLOGY; GENETIC PREDISPOSITION; GENETICS; META ANALYSIS; MIDDLE AGED; RISK FACTOR;

ADULT; AGED; ALCOHOL DEHYDROGENASE; ALCOHOL DRINKING; CARDIOVASCULAR DISEASES; COHORT STUDIES; CONFIDENCE INTERVALS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84857408636     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032176     Document Type: Article

References (45)

1. Ronksley PE, Brien SE, Turner BJ, Mukamal KJ, Ghali WA, (2011) Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis. BMJ 342: d671.
2. Brien SE, Ronksley PE, Turner BJ, Mukamal KJ, Ghali WA, (2011) Effect of alcohol consumption on biological markers associated with risk of coronary heart disease: systematic review and meta-analysis of interventional studies. BMJ 342: d636.
3. Smith GD, Timpson N, Ebrahim S, (2008) Strengthening causal inference in cardiovascular epidemiology through Mendelian randomization. Ann Med 40: 524-541.
4. Ehrig T, Bosron WF, Li TK, (1990) Alcohol and aldehyde dehydrogenase. Alcohol Alcohol 25: 105-116.
5. Djousse L, Levy D, Herbert AG, Wilson PW, D'Agostino RB, et al. (2005) Influence of alcohol dehydrogenase 1C polymorphism on the alcohol-cardiovascular disease association (from the Framingham Offspring Study). Am J Cardiol 96: 227-232.
6. Hoog JO, Heden LO, Larsson K, Jornvall H, von Bahr-Lindstrom H, (1986) The gamma 1 and gamma 2 subunits of human liver alcohol dehydrogenase. cDNA structures, two amino acid replacements, and compatibility with changes in the enzymatic properties. Eur J Biochem 159: 215-218.
7. Ebrahim S, Lawlor DA, Shlomo YB, Timpson N, Harbord R, et al. (2008) Alcohol dehydrogenase type 1C (ADH1C) variants, alcohol consumption traits, HDL-cholesterol and risk of coronary heart disease in women and men: British Women's Heart and Health Study and Caerphilly cohorts. Atherosclerosis 196: 871-878.
8. Heidrich J, Wellmann J, Doring A, Illig T, Keil U, (2007) Alcohol consumption, alcohol dehydrogenase and risk of coronary heart disease in the MONICA/KORA-Augsburg cohort 1994/1995-2002. Eur J Cardiovasc Prev Rehabil 14: 769-774.
9. Hines LM, Stampfer MJ, Ma J, Gaziano JM, Ridker PM, et al. (2001) Genetic variation in alcohol dehydrogenase and the beneficial effect of moderate alcohol consumption on myocardial infarction. N Engl J Med 344: 549-555.
10. Tolstrup JS, Gronbaek M, Nordestgaard BG, (2009) Alcohol intake, myocardial infarction, biochemical risk factors, and alcohol dehydrogenase genotypes. Circ Cardiovasc Genet 2: 507-514.
11. Tolstrup JS, Hansen JL, Gronbaek M, Vogel U, Tjonneland A, et al. (2010) Alcohol drinking habits, alcohol dehydrogenase genotypes and risk of acute coronary syndrome. Scand J Public Health 38: 489-494.
12. Younis J, Cooper JA, Miller GJ, Humphries SE, Talmud PJ, (2005) Genetic variation in alcohol dehydrogenase 1C and the beneficial effect of alcohol intake on coronary heart disease risk in the Second Northwick Park Heart Study. Atherosclerosis 180: 225-232.
13. Zee RY, Ridker PM, Cook NR, (2004) Prospective evaluation of the alcohol dehydrogenase gamma1/gamma2 gene polymorphism and risk of stroke. Stroke 35: e39-42.
14. Lee SL, Hoog JO, Yin SJ, (2004) Functionality of allelic variations in human alcohol dehydrogenase gene family: assessment of a functional window for protection against alcoholism. Pharmacogenetics 14: 725-732.
15. Suzuki Y, Fujisawa M, Ando F, Niino N, Ohsawa I, et al. (2004) Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae. Neurology 63: 1711-1713.
16. Boeing H, Korfmann A, Bergmann MM, (1999) Recruitment procedures of EPIC-Germany. European Investigation into Cancer and Nutrition. Ann Nutr Metab 43: 205-215.
17. Weikert C, Stefan N, Schulze MB, Pischon T, Berger K, et al. (2008) Plasma fetuin-a levels and the risk of myocardial infarction and ischemic stroke. Circulation 118: 2555-2562.
18. Prentice RL, (1986) A case-cohort design for epidemiologic cohort studies and disease prevention trials. BioMetrika 73: 1-11.
19. Bergmann MM, Bussas U, Boeing H, (1999) Follow-up procedures in EPIC-Germany-data quality aspects. European Prospective Investigation into Cancer and Nutrition. Ann Nutr Metab 43: 225-234.
20. Weikert C, Berger K, Heidemann C, Bergmann MM, Hoffmann K, et al. (2007) Joint effects of risk factors for stroke and transient ischemic attack in a German population: the EPIC Potsdam Study. J Neurol 254: 315-321.
21. World Health Organization (1992) Geneva, Switzerland World Health Organization.
22. Bohlscheid-Thomas S, Hoting I, Boeing H, Wahrendorf J, (1997) Reproducibility and relative validity of food group intake in a food frequency questionnaire developed for the German part of the EPIC project. European Prospective Investigation into Cancer and Nutrition. Int J Epidemiol 26: S59-70.
23. World Health Organization (2004) Department of Mental Health and Substance Abuse Geneva, Switzerland World Health Organization.
24. World Cancer Research Fund/American Institute for Cancer Research (2007) Washington, D.C. AICR.
25. Kroke A, Bergmann MM, Lotze G, Jeckel A, Klipstein-Grobusch K, et al. (1999) Measures of quality control in the German component of the EPIC study. European Prospective Investigation into Cancer and Nutrition. Ann Nutr Metab 43: 216-224.
26. Kim MY, Xue X, Du Y, (2006) Approaches for calculating power for case-cohort studies. Biometrics 62: 929-933; discussion 933.
27. Tolstrup JS, Nordestgaard BG, Rasmussen S, Tybjaerg-Hansen A, Gronbaek M, (2008) Alcoholism and alcohol drinking habits predicted from alcohol dehydrogenase genes. Pharmacogenomics J 8: 220-227.
28. Rothman J, Greenland S, Lash T, (2008) Introduction to Categorical Statistics Modern Epidemiology Lippincott, Williams, & Wilkins pp. 238-257.
29. Schwarzer G, (2011) Meta-Analysis with R. Available: http://cran.r-project.org/web/packages/meta/index.html. Accessed 2011 August 1.
30. DerSimonian R, Laird N, (1986) Meta-analysis in clinical trials. Control Clin Trials 7: 177-188.
31. Begg CB, Mazumdar M, (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50: 1088-1101.
32. Egger M, Davey Smith G, Schneider M, Minder C, (1997) Bias in meta-analysis detected by a simple, graphical test. Bmj 315: 629-634.
33. Corrao G, Rubbiati L, Bagnardi V, Zambon A, Poikolainen K, (2000) Alcohol and coronary heart disease: a meta-analysis. Addiction 95: 1505-1523.
34. Corrao G, Bagnardi V, Zambon A, La Vecchia C, (2004) A meta-analysis of alcohol consumption and the risk of 15 diseases. Prev Med 38: 613-619.
35. Patra J, Taylor B, Irving H, Roerecke M, Baliunas D, et al. (2010) Alcohol consumption and the risk of morbidity and mortality for different stroke types-a systematic review and meta-analysis. BMC Public Health 10: 258.
36. Roerecke M, Rehm J, (2011) Ischemic heart disease mortality and morbidity rates in former drinkers: a meta-analysis. Am J Epidemiol 173: 245-258.
37. Djousse L, Lee IM, Buring JE, Gaziano JM, (2009) Alcohol consumption and risk of cardiovascular disease and death in women: potential mediating mechanisms. Circulation 120: 237-244.
38. Macgregor S, Lind PA, Bucholz KK, Hansell NK, Madden PA, et al. (2009) Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis. Hum Mol Genet 18: 580-593.
39. Chen L, Davey Smith G, Harbord RM, Lewis SJ, (2008) Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach. PLoS Med 5: e52.
40. Lewis SJ, Smith GD, (2005) Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach. Cancer Epidemiol Biomarkers Prev 14: 1967-1971.
41. Hashibe M, Boffetta P, Zaridze D, Shangina O, Szeszenia-Dabrowska N, et al. (2006) Evidence for an important role of alcohol- and aldehyde-metabolizing genes in cancers of the upper aerodigestive tract. Cancer Epidemiol Biomarkers Prev 15: 696-703.
42. Zhang G, Mai R, Huang B, (2010) ADH1B Arg47His polymorphism is associated with esophageal cancer risk in high-incidence Asian population: evidence from a meta-analysis. PLoS One 5: e13679.
43. Schutze M, Boeing H, Pischon T, Rehm J, Kehoe T, et al. (2011) Alcohol attributable burden of incidence of cancer in eight European countries based on results from prospective cohort study. Bmj 342: d1584.
44. Bohlscheid-Thomas S, Hoting I, Boeing H, Wahrendorf J, (1997) Reproducibility and relative validity of energy and macronutrient intake of a food frequency questionnaire developed for the German part of the EPIC project. European Prospective Investigation into Cancer and Nutrition. Int J Epidemiol 26: S71-81.
45. Jia C, Liu T, Liu Z, Li M, Hu M, (2007) Joint effects of eNOS gene T-786C and ADH2 Arg47His polymorphisms on the risk of premature coronary artery disease. Thromb Res 120: 679-684.