Targeting phosphatidylinositol-3-kinase pathway for the treatment of Philadelphia-negative myeloproliferative neoplasms

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Pandey, Ruchi ^a   Kapur, Reuben ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chronic leukemia; JAK2; Mastocytosis; myeloproliferative neoplasms; PI3K inhibitors

Indexed keywords

2 (2 DIFLUOROMETHYLBENZIMIDAZOL 1 YL) 4,6 DIMORPHOLINO 1,3,5 TRIAZINE; 4 AMINO N [1 (4 CHLOROPHENYL) 3 HYDROXYPROPYL] 1 (7H PYRROLO[2,3 D]PYRIMIDIN 4 YL) 4 PIPERIDINECARBOXAMIDE; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; ANTINEOPLASTIC AGENT; ARQ 092; AZACITIDINE; BAY 1125976; BAY 806946; BUPARLISIB; CYTOKINE; DANAZOL; DECITABINE; IPATASERTIB; JANUS KINASE 2; LENALIDOMIDE; LY 2780301; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; ONC 201; PANOBINOSTAT; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; POMALIDOMIDE; PRACINOSTAT; PRM 151; PROTEIN KINASE B INHIBITOR; SIMTUZUMAB; SONIDEGIB; SONOLISIB; UNCLASSIFIED DRUG; UPROSERTIB;

ACUTE MYELOBLASTIC LEUKEMIA; ADVANCED CANCER; CANCER COMBINATION CHEMOTHERAPY; DRUG EFFICACY; DRUG TARGETING; ENZYME INHIBITION; HUMAN; LYMPHOMA; MASTOCYTOSIS; MOLECULAR PATHOLOGY; MULTIPLE MYELOMA; MYELOFIBROSIS; MYELOID METAPLASIA; MYELOPROLIFERATIVE NEOPLASM; NONHODGKIN LYMPHOMA; NONHUMAN; PHILADELPHIA CHROMOSOME NEGATIVE CELL; PROTEIN TARGETING; REVIEW; SOLID TUMOR; ANIMAL; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; MYELOPROLIFERATIVE DISORDERS; PHILADELPHIA 1 CHROMOSOME; SIGNAL TRANSDUCTION;

ANIMALS; CYTOKINES; HUMANS; MOLECULAR TARGETED THERAPY; MYELOPROLIFERATIVE DISORDERS; PHILADELPHIA CHROMOSOME; PHOSPHATIDYLINOSITOL 3-KINASE; SIGNAL TRANSDUCTION;

EID: 84934957618     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0388-z     Document Type: Review

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