메뉴 건너뛰기




Volumn 28, Issue SUPPL. 1, 2010, Pages

Deactylase inhibition in myeloproliferative neoplasms

Author keywords

Chronic myelogenous leukemia; Deactylase inhibition; Epigenetic therapy; Myeloproliferative neoplasms

Indexed keywords

2 (2 CHLORO 4 IODOANILINO) N CYCLOPROPYLMETHOXY 3,4 DIFLUOROBENZAMIDE; 5 AZA 2' DEOXYCYTIDINE; APICIDIN; BCR ABL PROTEIN; BUTYRIC ACID; DACINOSTAT; GAMMA INTERFERON; GIVINOSTAT; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; IMATINIB; N TERT BUTYL 3 [5 METHYL 2 [4 (4 METHYL 1 PIPERAZINYL)PHENYLAMINO] 4 PYRIMIDINYLAMINO]BENZENESULFONAMIDE; PANOBINOSTAT; PIVALOYLOXYMETHYL BUTYRATE; ROMIDEPSIN; SORAFENIB; TRICHOSTATIN A; VALPROIC ACID;

EID: 78651358562     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-010-9590-4     Document Type: Article
Times cited : (20)

References (101)
  • 3
    • 0033869862 scopus 로고    scopus 로고
    • The story of chronic myeloid leukaemia
    • DOI 10.1046/j.1365-2141.2000.02137.x
    • CG Geary 2000 The story of chronic myeloid leukaemia Br J Haematol 110 2 11 1:STN:280:DC%2BD3cvisVKjtw%3D%3D 10.1046/j.1365-2141.2000.02137.x 10930974 (Pubitemid 30625590)
    • (2000) British Journal of Haematology , vol.110 , Issue.1 , pp. 2-11
    • Geary, C.G.1
  • 6
    • 33646017748 scopus 로고    scopus 로고
    • Allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia in Europe 2006: Transplant activity, long-term data and current results. An analysis by the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT)
    • 16533723
    • A Gratwohl R Brand J Apperley, et al. 2006 Allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia in Europe 2006: transplant activity, long-term data and current results. An analysis by the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT) Haematologica 91 513 521 16533723
    • (2006) Haematologica , vol.91 , pp. 513-521
    • Gratwohl, A.1    Brand, R.2    Apperley, J.3
  • 8
    • 33947224197 scopus 로고    scopus 로고
    • New insights into the pathophysiology of chronic myeloid leukemia and imatinib resistance
    • HM Kantarjian M Talpaz F Giles S O'Brien J Cortes 2006 New insights into the pathophysiology of chronic myeloid leukemia and imatinib resistance Ann Intern 145 913 923 (Pubitemid 351639967)
    • (2006) Annals of Internal Medicine , vol.145 , Issue.12 , pp. 913-923
    • Kantarjian, H.M.1    Talpaz, M.2    Giles, F.3    O'Brien, S.4    Cortes, J.5
  • 9
    • 34247470836 scopus 로고    scopus 로고
    • Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia
    • DOI 10.1038/nrc2126, PII NRC2126
    • E Weisberg PW Manley SW Cowan-Jacob A Hochhaus JD Griffin 2007 Second generation inhibitors of BCR-ABL for the treatment of imatinib resistant chronic myeloid leukaemia Nat Rev Cancer 7 345 256 1:CAS:528:DC%2BD2sXksFSiu7o%3D 10.1038/nrc2126 17457302 (Pubitemid 46652483)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.5 , pp. 345-356
    • Weisberg, E.1    Manley, P.W.2    Cowan-Jacob, S.W.3    Hochhaus, A.4    Griffin, J.D.5
  • 10
    • 4544343214 scopus 로고    scopus 로고
    • A Bcr/Abl-independent, lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2
    • DOI 10.1074/jbc.M402290200
    • Y Dai, et al. 2004 A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2 J Biol Chem 279 33 34227 34239 1:CAS:528:DC%2BD2cXmvFent7g%3D 10.1074/jbc. M402290200 15175350 (Pubitemid 39318046)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.33 , pp. 34227-34239
    • Dai, Y.1    Rahmani, M.2    Corey, S.J.3    Dent, P.4    Grant, S.5
  • 13
    • 70349308652 scopus 로고    scopus 로고
    • Epigenetic therapy in myeloproliferative neoplasms: Evidence and perspectives
    • 1:CAS:528:DC%2BD1MXhtlGns7bP 10.1111/j.1582-4934.2009.00827.x 19522842
    • AM Vannucchi P Guglielmelli A Rambaldi C Bogani T Barbui 2009 Epigenetic therapy in myeloproliferative neoplasms: evidence and perspectives J Cell Mol Med 13 1437 1450 1:CAS:528:DC%2BD1MXhtlGns7bP 10.1111/j.1582-4934.2009.00827.x 19522842
    • (2009) J Cell Mol Med , vol.13 , pp. 1437-1450
    • Vannucchi, A.M.1    Guglielmelli, P.2    Rambaldi, A.3    Bogani, C.4    Barbui, T.5
  • 14
    • 33645740979 scopus 로고    scopus 로고
    • Minimal molecular response in polycythemia vera patients treated with imatinib or interferon alpha
    • 1:CAS:528:DC%2BD28Xjs1OksL0%3D 10.1182/blood-2005-09-3917 16352805
    • AV Jones RT Silver Waghorn, et al. 2006 Minimal molecular response in polycythemia vera patients treated with imatinib or interferon alpha Blood 107 3339 3341 1:CAS:528:DC%2BD28Xjs1OksL0%3D 10.1182/blood-2005-09-3917 16352805
    • (2006) Blood , vol.107 , pp. 3339-3341
    • Jones, A.V.1    Silver, R.T.2    Waghorn3
  • 15
    • 56249104095 scopus 로고    scopus 로고
    • Interferon-alpha therapy in bcr-abl-negative myeloproliferative neoplasms
    • 10.1038/leu.2008.280
    • JJ Kiladjian C Chomienne P Fenaux 2008 Interferon-alpha therapy in bcr-abl-negative myeloproliferative neoplasms Leukemia 122 1990 1998 10.1038/leu.2008.280
    • (2008) Leukemia , vol.122 , pp. 1990-1998
    • Kiladjian, J.J.1    Chomienne, C.2    Fenaux, P.3
  • 16
    • 54049141336 scopus 로고    scopus 로고
    • Pegylated Interferon-alfa-2a induces complete haematological and molecular responses with low toxicity in polycythemia vera
    • 1:CAS:528:DC%2BD1cXht1OmtbfE 10.1182/blood-2008-03-143537 18650451
    • JJ Kiladjian B Cassinat S Chevret, et al. 2008 Pegylated Interferon-alfa-2a induces complete haematological and molecular responses with low toxicity in polycythemia vera Blood 112 3065 3072 1:CAS:528: DC%2BD1cXht1OmtbfE 10.1182/blood-2008-03-143537 18650451
    • (2008) Blood , vol.112 , pp. 3065-3072
    • Kiladjian, J.J.1    Cassinat, B.2    Chevret, S.3
  • 17
    • 58249096418 scopus 로고    scopus 로고
    • 5-Azacitidine has limited therapeutic activity in myelofibrosis
    • 1:CAS:528:DC%2BD1MXkvVeisQ%3D%3D 10.1038/leu.2008.136 18509350
    • RA Mesa S Verstovek C Rivera, et al. 2009 5-Azacitidine has limited therapeutic activity in myelofibrosis Leukemia 23 180 182 1:CAS:528: DC%2BD1MXkvVeisQ%3D%3D 10.1038/leu.2008.136 18509350
    • (2009) Leukemia , vol.23 , pp. 180-182
    • Mesa, R.A.1    Verstovek, S.2    Rivera, C.3
  • 18
    • 39749167036 scopus 로고    scopus 로고
    • New and old treatment modalities in primary myelofibrosis
    • 1:CAS:528:DC%2BD2sXhsVGgtr%2FE 10.1097/PPO.0b013e31815a7c0a 18032975
    • F Cervantes R Mesa G Barosi 2007 New and old treatment modalities in primary myelofibrosis Cancer J 13 377 383 1:CAS:528:DC%2BD2sXhsVGgtr%2FE 10.1097/PPO.0b013e31815a7c0a 18032975
    • (2007) Cancer J , vol.13 , pp. 377-383
    • Cervantes, F.1    Mesa, R.2    Barosi, G.3
  • 20
    • 49449108604 scopus 로고    scopus 로고
    • Bortezomib therapy in myelofibrosis: A phase II clinical trial
    • 1:CAS:528:DC%2BD1cXpslSnurk%3D 10.1038/leu.2008.32 18305559
    • RA Mesa S Verstovsek C Rivera, et al. 2008 Bortezomib therapy in myelofibrosis: a phase II clinical trial Leukemia 22 1636 1638 1:CAS:528:DC%2BD1cXpslSnurk%3D 10.1038/leu.2008.32 18305559
    • (2008) Leukemia , vol.22 , pp. 1636-1638
    • Mesa, R.A.1    Verstovsek, S.2    Rivera, C.3
  • 21
    • 34447634117 scopus 로고    scopus 로고
    • Lenalidomide therapy in del(5)(q31)-associated myelofibrosis: Cytogenetic and JAK2V617F molecular remissions [5]
    • DOI 10.1038/sj.leu.2404711, PII 2404711
    • A Tefferi TL Lasho RA Mesa, et al. 2007 Lenalidomide therapy in del(5)(q31)-associated myelofibrosis: cytogenetic and JAK2V617F molecular remissions Leukemia 21 1827 1828 1:CAS:528:DC%2BD2sXnvVeltrg%3D 10.1038/sj.leu.2404711 17460705 (Pubitemid 47086775)
    • (2007) Leukemia , vol.21 , Issue.8 , pp. 1827-1828
    • Tefferi, A.1    Lasho, T.L.2    Mesa, R.A.3    Pardanani, A.4    Ketterling, R.P.5    Hanson, C.A.6
  • 22
    • 77950684805 scopus 로고    scopus 로고
    • Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: Therapeutic implications for the treatment of myeloproliferative neoplasms
    • 1:CAS:528:DC%2BC3cXltlWqsr8%3D 10.1182/blood-2009-04-214957 20130243
    • A Quintas-Cardama K Vaddi P Liu, et al. 2010 Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms Blood 115 3109 3117 1:CAS:528:DC%2BC3cXltlWqsr8%3D 10.1182/blood-2009-04-214957 20130243
    • (2010) Blood , vol.115 , pp. 3109-3117
    • Quintas-Cardama, A.1    Vaddi, K.2    Liu, P.3
  • 23
    • 34547792388 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer: The DNA hypermethylome
    • DOI 10.1093/hmg/ddm018, Cancer Genetics
    • M Esteller 2007 Epigenetic gene silencing in cancer: the DNA hypermethylome Hum Mol Genet 16 Spec No 1 50 59 10.1093/hmg/ddm018 (Pubitemid 47241842)
    • (2007) Human Molecular Genetics , vol.16 , Issue.R1
    • Esteller, M.1
  • 24
    • 20144388146 scopus 로고    scopus 로고
    • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
    • 1:CAS:528:DC%2BD2MXislCmurg%3D 10.1038/ng1531 15765097
    • MF Fraga, et al. 2005 Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer Nat Genet 37 4 391 400 1:CAS:528:DC%2BD2MXislCmurg%3D 10.1038/ng1531 15765097
    • (2005) Nat Genet , vol.37 , Issue.4 , pp. 391-400
    • Fraga, M.F.1
  • 25
    • 61849144810 scopus 로고    scopus 로고
    • HDAC family: What are the cancer relevant targets?
    • 1:CAS:528:DC%2BD1MXjtFOhsL4%3D 10.1016/j.canlet.2008.08.016 18824292
    • O Witt, et al. 2009 HDAC family: what are the cancer relevant targets? Cancer Lett 277 1 8 21 1:CAS:528:DC%2BD1MXjtFOhsL4%3D 10.1016/j.canlet.2008.08. 016 18824292
    • (2009) Cancer Lett , vol.277 , Issue.1 , pp. 8-21
    • Witt, O.1
  • 26
    • 0034968671 scopus 로고    scopus 로고
    • Histone acetylation and disease
    • 1:CAS:528:DC%2BD3MXlt1ait7s%3D 10.1007/PL00000896 11437234
    • S Timmermann, et al. 2001 Histone acetylation and disease Cell Mol Life Sci 58 5-6 728 736 1:CAS:528:DC%2BD3MXlt1ait7s%3D 10.1007/PL00000896 11437234
    • (2001) Cell Mol Life Sci , vol.58 , Issue.56 , pp. 728-736
    • Timmermann, S.1
  • 27
    • 33748308794 scopus 로고    scopus 로고
    • JAK signaling globally counteracts heterochromatic gene silencing
    • DOI 10.1038/ng1860, PII NG1860
    • S Shi HC Calhoun F Xia, et al. 2006 JAK signalling globally counteracts heterochromatic gene silencing Nat Genet 38 1071 1076 1:CAS:528: DC%2BD28XovVWjtrw%3D 10.1038/ng1860 16892059 (Pubitemid 44325935)
    • (2006) Nature Genetics , vol.38 , Issue.9 , pp. 1071-1076
    • Shi, S.1    Calhoun, H.C.2    Xia, F.3    Li, J.4    Le, L.5    Li, W.X.6
  • 28
    • 33746651038 scopus 로고    scopus 로고
    • STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes
    • DOI 10.1182/blood-2005-08-007377
    • Q Zhang HY Wang A Woetmannn, et al. 2006 STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T cells Blood 108 1058 1064 1:CAS:528:DC%2BD28XnvFajur8%3D 10.1182/blood-2005-08-007377 16861352 (Pubitemid 44154645)
    • (2006) Blood , vol.108 , Issue.3 , pp. 1058-1064
    • Zhang, Q.1    Wang, H.Y.2    Woetmann, A.3    Raghunath, P.N.4    Odum, N.5    Wasik, M.A.6
  • 29
    • 57449089334 scopus 로고    scopus 로고
    • Epigenetic alterations and anti-epigenetic therapy in myelofibrosis
    • 10.1080/10428190802578866 19052966
    • A Tefferi 2008 Epigenetic alterations and anti-epigenetic therapy in myelofibrosis Leuk Lymphoma 49 2231 2232 10.1080/10428190802578866 19052966
    • (2008) Leuk Lymphoma , vol.49 , pp. 2231-2232
    • Tefferi, A.1
  • 30
    • 57449114002 scopus 로고    scopus 로고
    • Enhanced histone deacetylase enzyme activity in primary myelofibrosis
    • 1:CAS:528:DC%2BD1cXhsVGqu7fK 10.1080/10428190802527699 19052980
    • JC Wang, et al. 2008 Enhanced histone deacetylase enzyme activity in primary myelofibrosis Leuk Lymphoma 49 12 2321 2327 1:CAS:528:DC%2BD1cXhsVGqu7fK 10.1080/10428190802527699 19052980
    • (2008) Leuk Lymphoma , vol.49 , Issue.12 , pp. 2321-2327
    • Wang, J.C.1
  • 31
    • 55549126446 scopus 로고    scopus 로고
    • Methylation of the suppressor of cytokine signalling 3 gene (SOCS3) in myeloproliferative disorders
    • 10.3324/haematol.13043
    • N Fourcouclas J Li DC Gilby, et al. 2008 Methylation of the suppressor of cytokine signalling 3 gene (SOCS3) in myeloproliferative disorders Haematologica 93 1635 1644 10.3324/haematol.13043
    • (2008) Haematologica , vol.93 , pp. 1635-1644
    • Fourcouclas, N.1    Li, J.2    Gilby, D.C.3
  • 33
    • 44749094529 scopus 로고    scopus 로고
    • Methylation status of SOCS1 and SOCS3 in BCR-ABL negative and JAK2V617F negative chronic myeloproliferative neoplasms
    • 1:CAS:528:DC%2BD1cXntlGgsLc%3D 10.1016/j.leukres.2008.03.014 18440067
    • M Fernandez-Mercado V Cebrian B Euba, et al. 2008 Methylation status of SOCS1 and SOCS3 in BCR-ABL negative and JAK2V617F negative chronic myeloproliferative neoplasms Leuk Res 32 1638 1640 1:CAS:528: DC%2BD1cXntlGgsLc%3D 10.1016/j.leukres.2008.03.014 18440067
    • (2008) Leuk Res , vol.32 , pp. 1638-1640
    • Fernandez-Mercado, M.1    Cebrian, V.2    Euba, B.3
  • 34
    • 33847223121 scopus 로고    scopus 로고
    • Epigenetic alterations complement mutations of JAK2 tyrosine kinase in patients with BCR/ABL-negative myeloproliferative disorders
    • 1:CAS:528:DC%2BD2sXhvFWksLs%3D 10.1038/sj.leu.2404513 17230231
    • E Jost ON do E Dahl 2007 Epigenetic alterations complement mutations of JAK2 tyrosine kinase in patients with BCR/ABL-negative myeloproliferative disorders Leukemia 21 505 510 1:CAS:528:DC%2BD2sXhvFWksLs%3D 10.1038/sj.leu.2404513 17230231
    • (2007) Leukemia , vol.21 , pp. 505-510
    • Jost, E.1    Do, O.N.2    Dahl, E.3
  • 37
    • 55049114480 scopus 로고    scopus 로고
    • Hypermethylation of CXCR4 promoter in the CD34+ cells from patients with primary myelofibrosis
    • 1:CAS:528:DC%2BD1cXhtVKmt77F 10.1634/stemcells.2008-0377 18511598
    • C Bogani V Ponziani P Gugliemelli, et al. 2008 Hypermethylation of CXCR4 promoter in the CD34+ cells from patients with primary myelofibrosis Stem Cells 26 1920 1930 1:CAS:528:DC%2BD1cXhtVKmt77F 10.1634/stemcells.2008-0377 18511598
    • (2008) Stem Cells , vol.26 , pp. 1920-1930
    • Bogani, C.1    Ponziani, V.2    Gugliemelli, P.3
  • 38
    • 70349307696 scopus 로고    scopus 로고
    • Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin modifying agents
    • X Wang W Zhang T Ishii, et al. 2008 Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin modifying agents Blood 112 101A
    • (2008) Blood , vol.112
    • Wang, X.1    Zhang, W.2    Ishii, T.3
  • 40
    • 42049096709 scopus 로고    scopus 로고
    • Azacitidine (AZA) treatment prolongs overall survival (OS) in higher-risk MDS patients compared with conventional care regimens (CCR)
    • P Fenaux GJ Mufti V Santini, et al. 2007 Azacitidine (AZA) treatment prolongs overall survival (OS) in higher-risk MDS patients compared with conventional care regimens (CCR) Blood 110 817
    • (2007) Blood , vol.110 , pp. 817
    • Fenaux, P.1    Mufti, G.J.2    Santini, V.3
  • 42
    • 57749170458 scopus 로고    scopus 로고
    • The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
    • 1:CAS:528:DC%2BD1cXhsFWis7bI 10.1038/nrg2485 19065135
    • M Haberland, et al. 2009 The many roles of histone deacetylases in development and physiology: implications for disease and therapy Nat Rev Genet 10 1 32 42 1:CAS:528:DC%2BD1cXhsFWis7bI 10.1038/nrg2485 19065135
    • (2009) Nat Rev Genet , vol.10 , Issue.1 , pp. 32-42
    • Haberland, M.1
  • 43
    • 66049146095 scopus 로고    scopus 로고
    • Genetic dissection of histone deacetylase requirement in tumor cells
    • 1:CAS:528:DC%2BD1MXmt1ams7o%3D 10.1073/pnas.0903139106 19416910
    • M Haberland, et al. 2009 Genetic dissection of histone deacetylase requirement in tumor cells Proc Natl Acad Sci USA 106 19 7751 7755 1:CAS:528:DC%2BD1MXmt1ams7o%3D 10.1073/pnas.0903139106 19416910
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.19 , pp. 7751-7755
    • Haberland, M.1
  • 44
    • 0036386359 scopus 로고    scopus 로고
    • Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation
    • 1:CAS:528:DC%2BD38XpsVyisrw%3D 10.1016/S0065-230X(02)86002-X 12374280
    • H Lehrmann, et al. 2002 Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation Adv Cancer Res 86 41 65 1:CAS:528:DC%2BD38XpsVyisrw%3D 10.1016/S0065-230X(02)86002-X 12374280
    • (2002) Adv Cancer Res , vol.86 , pp. 41-65
    • Lehrmann, H.1
  • 46
    • 56049090769 scopus 로고    scopus 로고
    • Acetylation of non-histone proteins modulates cellular signalling at multiple levels
    • 1:CAS:528:DC%2BD1cXhsVWnu7zP 10.1016/j.biocel.2008.08.027 18804549
    • S Spange, et al. 2009 Acetylation of non-histone proteins modulates cellular signalling at multiple levels Int J Biochem Cell Biol 41 1 185 198 1:CAS:528:DC%2BD1cXhsVWnu7zP 10.1016/j.biocel.2008.08.027 18804549
    • (2009) Int J Biochem Cell Biol , vol.41 , Issue.1 , pp. 185-198
    • Spange, S.1
  • 47
    • 28044471827 scopus 로고    scopus 로고
    • Acetylation and deacetylation of non-histone proteins
    • DOI 10.1016/j.gene.2005.09.010, PII S037811190500572X
    • MA Glozak, et al. 2005 Acetylation and deacetylation of non-histone proteins Gene 363 15 23 1:CAS:528:DC%2BD2MXht1Klu7%2FN 10.1016/j.gene.2005.09. 010 16289629 (Pubitemid 41691888)
    • (2005) Gene , vol.363 , Issue.1-2 , pp. 15-23
    • Glozak, M.A.1    Sengupta, N.2    Zhang, X.3    Seto, E.4
  • 48
    • 34547897023 scopus 로고    scopus 로고
    • Histone deacetylases and cancer
    • DOI 10.1038/sj.onc.1210610, PII 1210610
    • MA Glozak, et al. 2007 Histone deacetylases and cancer Oncogene 26 37 5420 5432 1:CAS:528:DC%2BD2sXovFeku7Y%3D 10.1038/sj.onc.1210610 17694083 (Pubitemid 47255924)
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5420-5432
    • Glozak, M.A.1    Seto, E.2
  • 49
  • 50
    • 33748451151 scopus 로고    scopus 로고
    • Anticancer activities of histone deacetylase inhibitors
    • DOI 10.1038/nrd2133, PII NRD2133
    • JE Bolden, et al. 2006 Anticancer activities of histone deacetylase inhibitors Nat Rev Drug Discov 5 9 769 784 1:CAS:528:DC%2BD28XptVCltrY%3D 10.1038/nrd2133 16955068 (Pubitemid 44348499)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.9 , pp. 769-784
    • Bolden, J.E.1    Peart, M.J.2    Johnstone, R.W.3
  • 51
    • 30344477367 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
    • DOI 10.1038/nrc1779
    • S Minucci, et al. 2006 Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer Nat Rev Cancer 6 1 38 51 1:CAS:528:DC%2BD28Xht1GgsA%3D%3D 10.1038/nrc1779 16397526 (Pubitemid 43054973)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.1 , pp. 38-51
    • Minucci, S.1    Pelicci, P.G.2
  • 52
    • 34547864236 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Molecular mechanisms of action
    • DOI 10.1038/sj.onc.1210620, PII 1210620
    • WS Xu, et al. 2007 Histone deacetylase inhibitors: molecular mechanisms of action Oncogene 26 37 5541 5552 1:CAS:528:DC%2BD2sXovFersrY%3D 10.1038/sj.onc.1210620 17694093 (Pubitemid 47255934)
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5541-5552
    • Xu, W.S.1    Parmigiani, R.B.2    Marks, P.A.3
  • 53
    • 0035933731 scopus 로고    scopus 로고
    • Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts
    • 1:CAS:528:DC%2BD3MXkvVams7Y%3D 10.1074/jbc.M100206200 11304533
    • H Brinkmann, et al. 2001 Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts J Biol Chem 276 25 22491 22499 1:CAS:528:DC%2BD3MXkvVams7Y%3D 10.1074/jbc.M100206200 11304533
    • (2001) J Biol Chem , vol.276 , Issue.25 , pp. 22491-22499
    • Brinkmann, H.1
  • 54
    • 4644304383 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors specifically kill nonproliferating tumour cells
    • DOI 10.1038/sj.onc.1207893
    • A Burgess, et al. 2004 Histone deacetylase inhibitors specifically kill nonproliferating tumour cells Oncogene 23 40 6693 6701 1:CAS:528: DC%2BD2cXntFGnu7o%3D 10.1038/sj.onc.1207893 15235588 (Pubitemid 39280001)
    • (2004) Oncogene , vol.23 , Issue.40 , pp. 6693-6701
    • Burgess, A.1    Ruefli, A.2    Beamish, H.3    Warrener, R.4    Saunders, N.5    Johnstone, R.6    Gabrielli, B.7
  • 55
    • 0034802325 scopus 로고    scopus 로고
    • Up-regulation of p21(WAF1/CIP1) by histone deacetylase inhibitors reduces their cytotoxicity
    • 1:CAS:528:DC%2BD3MXnt1ersrk%3D 11562446
    • AJ Burgess, et al. 2001 Up-regulation of p21(WAF1/CIP1) by histone deacetylase inhibitors reduces their cytotoxicity Mol Pharmacol 60 4 828 837 1:CAS:528:DC%2BD3MXnt1ersrk%3D 11562446
    • (2001) Mol Pharmacol , vol.60 , Issue.4 , pp. 828-837
    • Burgess, A.J.1
  • 56
    • 0034086168 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells
    • 1:CAS:528:DC%2BD3cXkt1Sisbc%3D 10848630
    • L Qiu, et al. 2000 Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells Mol Biol Cell 11 6 2069 2083 1:CAS:528:DC%2BD3cXkt1Sisbc%3D 10848630
    • (2000) Mol Biol Cell , vol.11 , Issue.6 , pp. 2069-2083
    • Qiu, L.1
  • 57
    • 25144487124 scopus 로고    scopus 로고
    • Mechanisms of selective anticancer action of histone deacetylase inhibitors
    • 1:CAS:528:DC%2BD28XhslCqtr8%3D 10.4161/cc.4.6.1717 15908787
    • A Insinga, et al. 2005 Mechanisms of selective anticancer action of histone deacetylase inhibitors Cell Cycle 4 6 741 743 1:CAS:528: DC%2BD28XhslCqtr8%3D 10.4161/cc.4.6.1717 15908787
    • (2005) Cell Cycle , vol.4 , Issue.6 , pp. 741-743
    • Insinga, A.1
  • 58
    • 0034032012 scopus 로고    scopus 로고
    • BCR-ABL tyrosine kinase activity regulates the expression of multiple genes implicated in the pathogenesis of chronic myeloid leukemia
    • 1:CAS:528:DC%2BD3cXisVymsrc%3D 10766197
    • MW Deininger, et al. 2000 BCR-ABL tyrosine kinase activity regulates the expression of multiple genes implicated in the pathogenesis of chronic myeloid leukemia Cancer Res 60 7 2049 2055 1:CAS:528:DC%2BD3cXisVymsrc%3D 10766197
    • (2000) Cancer Res , vol.60 , Issue.7 , pp. 2049-2055
    • Deininger, M.W.1
  • 59
    • 0037186924 scopus 로고    scopus 로고
    • Imatinib mesylate - A new oral targeted therapy
    • DOI 10.1056/NEJMra013339
    • DG Savage, et al. 2002 Imatinib mesylate-a new oral targeted therapy N Engl J Med 346 9 683 693 1:CAS:528:DC%2BD38XhsFOjsro%3D 10.1056/NEJMra013339 11870247 (Pubitemid 34815874)
    • (2002) New England Journal of Medicine , vol.346 , Issue.9 , pp. 683-693
    • Savage, D.G.1    Antman, K.H.2
  • 60
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
    • DOI 10.1126/science.1062538
    • ME Gorre, et al. 2001 Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification Science 293 5531 876 880 1:CAS:528:DC%2BD3MXlvVKrsbs%3D 10.1126/science.1062538 11423618 (Pubitemid 32743979)
    • (2001) Science , vol.293 , Issue.5531 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3    Hsu, N.4    Paquette, R.5    Nagesh Rao, P.6    Sawyers, C.L.7
  • 61
    • 0001686739 scopus 로고    scopus 로고
    • Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
    • DOI 10.1016/S1535-6108(02)00096-X
    • NP Shah, et al. 2002 Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia Cancer Cell 2 2 117 125 1:CAS:528:DC%2BD38XmslSks7c%3D 10.1016/S1535-6108(02)00096-X 12204532 (Pubitemid 41039112)
    • (2002) Cancer Cell , vol.2 , Issue.2 , pp. 117-125
    • Shah, N.P.1    Nicoll, J.M.2    Nagar, B.3    Gorre, M.E.4    Paquette, R.L.5    Kuriyan, J.6    Sawyers, C.L.7
  • 62
    • 77949439646 scopus 로고    scopus 로고
    • Dasatinib in chronic myeloid leukemia: A review
    • 1:CAS:528:DC%2BD1MXpt1yltL4%3D 19536317
    • DG Aguilera, et al. 2009 Dasatinib in chronic myeloid leukemia: a review Ther Clin Risk Manag 5 2 281 289 1:CAS:528:DC%2BD1MXpt1yltL4%3D 19536317
    • (2009) Ther Clin Risk Manag , vol.5 , Issue.2 , pp. 281-289
    • Aguilera, D.G.1
  • 63
    • 77953673237 scopus 로고    scopus 로고
    • Nilotinib: Optimal therapy for patients with chronic myeloid leukemia and resistance or intolerance to imatinib
    • 1:CAS:528:DC%2BD1MXoslSms7c%3D 19920925
    • R Swords, et al. 2009 Nilotinib: optimal therapy for patients with chronic myeloid leukemia and resistance or intolerance to imatinib Drug Des Devel Ther 3 89 101 1:CAS:528:DC%2BD1MXoslSms7c%3D 19920925
    • (2009) Drug des Devel Ther , vol.3 , pp. 89-101
    • Swords, R.1
  • 64
  • 65
    • 20844444898 scopus 로고    scopus 로고
    • Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3
    • DOI 10.1182/blood-2004-09-3413
    • P George, et al. 2005 Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3 Blood 105 4 1768 1776 1:CAS:528:DC%2BD2MXhsVGjsL4%3D 10.1182/blood-2004-09-3413 15514006 (Pubitemid 40223701)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1768-1776
    • George, P.1    Bali, P.2    Annavarapu, S.3    Scuto, A.4    Fiskus, W.5    Guo, F.6    Sigua, C.7    Sondarva, G.8    Moscinski, L.9    Atadja, P.10    Bhalla, K.11
  • 66
    • 33644505789 scopus 로고    scopus 로고
    • Valproate enhances imatinib-induced growth arrest and apoptosis in chronic myeloid leukemia cells
    • 1:CAS:528:DC%2BD28Xis1agtL8%3D 10.1002/cncr.21725 16444746
    • A Morotti, et al. 2006 Valproate enhances imatinib-induced growth arrest and apoptosis in chronic myeloid leukemia cells Cancer 106 5 1188 1196 1:CAS:528:DC%2BD28Xis1agtL8%3D 10.1002/cncr.21725 16444746
    • (2006) Cancer , vol.106 , Issue.5 , pp. 1188-1196
    • Morotti, A.1
  • 67
    • 0043016178 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor LAQ824 both lowers expression and promotes proteasomal degradation of Bcr-Abl and induces apoptosis of imatinib mesylate-sensitive or -refractory chronic myelogenous leukemia-blast crisis cells
    • 1:CAS:528:DC%2BD3sXms12ntro%3D 12941844
    • R Nimmanapalli, et al. 2003 Histone deacetylase inhibitor LAQ824 both lowers expression and promotes proteasomal degradation of Bcr-Abl and induces apoptosis of imatinib mesylate-sensitive or -refractory chronic myelogenous leukemia-blast crisis cells Cancer Res 63 16 5126 5135 1:CAS:528: DC%2BD3sXms12ntro%3D 12941844
    • (2003) Cancer Res , vol.63 , Issue.16 , pp. 5126-5135
    • Nimmanapalli, R.1
  • 68
    • 0038620379 scopus 로고    scopus 로고
    • Cotreatment with the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) enhances imatinib-induced apoptosis of Bcr-Abl-positive human acute leukemia cells
    • DOI 10.1182/blood-2002-08-2675
    • R Nimmanapalli, et al. 2003 Cotreatment with the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) enhances imatinib-induced apoptosis of Bcr-Abl-positive human acute leukemia cells Blood 101 8 3236 3239 1:CAS:528:DC%2BD3sXjtFCqtbg%3D 10.1182/blood-2002-08-2675 12446442 (Pubitemid 36858020)
    • (2003) Blood , vol.101 , Issue.8 , pp. 3236-3239
    • Nimmanapalli, R.1    Fuino, L.2    Stobaugh, C.3    Richon, V.4    Bhalla, K.5
  • 69
    • 21644464967 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor suberoylanilide hydroxamic acid down-regulates expression levels of Bcr-abl, c-Myc and HDAC3 in chronic myeloid leukemia cell lines
    • 1:CAS:528:DC%2BD2MXmsFeiug%3D%3D 15583844
    • Y Xu, et al. 2005 The histone deacetylase inhibitor suberoylanilide hydroxamic acid down-regulates expression levels of Bcr-abl, c-Myc and HDAC3 in chronic myeloid leukemia cell lines Int J Mol Med 15 1 169 172 1:CAS:528:DC%2BD2MXmsFeiug%3D%3D 15583844
    • (2005) Int J Mol Med , vol.15 , Issue.1 , pp. 169-172
    • Xu, Y.1
  • 70
    • 50949133899 scopus 로고    scopus 로고
    • Vorinostat synergistically potentiates MK-0457 lethality in chronic myelogenous leukemia cells sensitive and resistant to imatinib mesylate
    • 1:CAS:528:DC%2BD1cXpsVais78%3D 10.1182/blood-2007-10-116376 18505786
    • Y Dai, et al. 2008 Vorinostat synergistically potentiates MK-0457 lethality in chronic myelogenous leukemia cells sensitive and resistant to imatinib mesylate Blood 112 3 793 804 1:CAS:528:DC%2BD1cXpsVais78%3D 10.1182/blood-2007-10-116376 18505786
    • (2008) Blood , vol.112 , Issue.3 , pp. 793-804
    • Dai, Y.1
  • 71
    • 34347394714 scopus 로고    scopus 로고
    • Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHAto overcome Bcr-Abl-mediated drug resistance
    • DOI 10.1182/blood-2006-10-050260
    • JS Carew, et al. 2007 Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance Blood 110 1 313 322 1:CAS:528:DC%2BD2sXnsVaitrw%3D 10.1182/blood-2006-10-050260 17363733 (Pubitemid 47026849)
    • (2007) Blood , vol.110 , Issue.1 , pp. 313-322
    • Carew, J.S.1    Nawrocki, S.T.2    Kahue, C.N.3    Zhang, H.4    Yang, C.5    Chung, L.6    Houghton, J.A.7    Huang, P.8    Giles, F.J.9    Cleveland, J.L.10
  • 72
    • 33750303818 scopus 로고    scopus 로고
    • Cotreatment with vorinostat (suberoylanilide hydroxamic acid) enhances activity of dasatinib (BMS-354825) against imatinib mesylate-sensitive or imatinib mesylate-resistant chronic myelogenous leukemia cells
    • DOI 10.1158/1078-0432.CCR-06-0980
    • W Fiskus, et al. 2006 Cotreatment with vorinostat (suberoylanilide hydroxamic acid) enhances activity of dasatinib (BMS-354825) against imatinib mesylate-sensitive or imatinib mesylate-resistant chronic myelogenous leukemia cells Clin Cancer Res 12 19 5869 5878 1:CAS:528:DC%2BD28XhtVartbnM 10.1158/1078-0432.CCR-06-0980 17020995 (Pubitemid 44629620)
    • (2006) Clinical Cancer Research , vol.12 , Issue.19 , pp. 5869-5878
    • Fiskus, W.1    Pranpat, M.2    Balasis, M.3    Bali, P.4    Estrella, V.5    Kumaraswamy, S.6    Rao, R.7    Rocha, K.8    Herger, B.9    Lee, F.10    Richon, V.11    Bhalla, K.12
  • 73
    • 26944440597 scopus 로고    scopus 로고
    • Synergistic interactions between MEK1/2 and histone deacetylase inhibitors in BCR/ABL+ human leukemia cells
    • DOI 10.1038/sj.leu.2403868, PII 2403868
    • C Yu, et al. 2005 Synergistic interactions between MEK1/2 and histone deacetylase inhibitors in BCR/ABL+ human leukemia cells Leukemia 19 9 1579 1589 1:CAS:528:DC%2BD2MXovVOjurk%3D 10.1038/sj.leu.2403868 16015388 (Pubitemid 43090402)
    • (2005) Leukemia , vol.19 , Issue.9 , pp. 1579-1589
    • Yu, C.1    Dasmahapatra, G.2    Dent, P.3    Grant, S.4
  • 74
    • 77955277307 scopus 로고    scopus 로고
    • Bcr-Abl-independent mechanism of resistance to imatinib in K562 cells: Induction of cyclooxygenase-2 (COX-2) by histone deacetylases (HDACs)
    • Kalle AM et al (2010) Bcr-Abl-independent mechanism of resistance to imatinib in K562 cells: Induction of cyclooxygenase-2 (COX-2) by histone deacetylases (HDACs). Leuk Res
    • (2010) Leuk Res
    • Kalle, A.M.1
  • 75
    • 34248193440 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer therapy
    • DOI 10.1517/13543784.16.5.659
    • WK Rasheed, et al. 2007 Histone deacetylase inhibitors in cancer therapy Expert Opin Investig Drugs 16 5 659 678 1:CAS:528:DC%2BD2sXks1aht78%3D 10.1517/13543784.16.5.659 17461739 (Pubitemid 46729100)
    • (2007) Expert Opinion on Investigational Drugs , vol.16 , Issue.5 , pp. 659-678
    • Rasheed, W.K.1    Johnstone, R.W.2    Prince, H.M.3
  • 76
    • 58149144779 scopus 로고    scopus 로고
    • Cotreatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cells
    • 1:CAS:528:DC%2BD1cXhtF2nurvO 10.1158/1078-0432.CCR-08-0721 18829489
    • W Fiskus, et al. 2008 Cotreatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cells Clin Cancer Res 14 19 6106 6115 1:CAS:528:DC%2BD1cXhtF2nurvO 10.1158/1078-0432.CCR- 08-0721 18829489
    • (2008) Clin Cancer Res , vol.14 , Issue.19 , pp. 6106-6115
    • Fiskus, W.1
  • 77
    • 34547161973 scopus 로고    scopus 로고
    • CIP1 down-regulation
    • DOI 10.1158/1078-0432.CCR-07-0835
    • G Dasmahapatra, et al. 2007 Synergistic interactions between vorinostat and sorafenib in chronic myelogenous leukemia cells involve Mcl-1 and p21CIP1 down-regulation Clin Cancer Res 13 14 4280 4290 1:CAS:528:DC%2BD2sXnvVChtro%3D 10.1158/1078-0432.CCR-07-0835 17634558 (Pubitemid 47108172)
    • (2007) Clinical Cancer Research , vol.13 , Issue.14 , pp. 4280-4290
    • Dasmahapatra, G.1    Yerram, N.2    Dai, Y.3    Dent, P.4    Grant, S.5
  • 78
    • 0242493856 scopus 로고    scopus 로고
    • + cells sensitive and resistant to STI571
    • DOI 10.1182/blood-2003-03-0737
    • C Yu, et al. 2003 The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571 Blood 102 10 3765 3774 1:CAS:528:DC%2BD3sXptVymtb0%3D 10.1182/blood-2003-03-0737 12893773 (Pubitemid 37409399)
    • (2003) Blood , vol.102 , Issue.10 , pp. 3765-3774
    • Yu, C.1    Rahmani, M.2    Conrad, D.3    Subler, M.4    Dent, P.5    Grant, S.6
  • 79
    • 67349264883 scopus 로고    scopus 로고
    • Cotreatment with apicidin overcomes TRAIL resistance via inhibition of Bcr-Abl signaling pathway in K562 leukemia cells
    • 1:CAS:528:DC%2BD1MXms1Oqur8%3D 10.1016/j.yexcr.2009.02.024 19268463
    • SJ Park, et al. 2009 Cotreatment with apicidin overcomes TRAIL resistance via inhibition of Bcr-Abl signaling pathway in K562 leukemia cells Exp Cell Res 315 11 1809 1818 1:CAS:528:DC%2BD1MXms1Oqur8%3D 10.1016/j.yexcr.2009.02.024 19268463
    • (2009) Exp Cell Res , vol.315 , Issue.11 , pp. 1809-1818
    • Park, S.J.1
  • 80
    • 6444226076 scopus 로고    scopus 로고
    • Depsipeptide enhances imatinib mesylate-induced apoptosis of Bcr-Abl-positive cells and ectopic expression of cyclin D1, c-Myc or active MEK abrogates this effect
    • 1:CAS:528:DC%2BD2cXhtVSjsL3L 15517875
    • T Kawano, et al. 2004 Depsipeptide enhances imatinib mesylate-induced apoptosis of Bcr-Abl-positive cells and ectopic expression of cyclin D1, c-Myc or active MEK abrogates this effect Anticancer Res 24 5A 2705 2712 1:CAS:528:DC%2BD2cXhtVSjsL3L 15517875
    • (2004) Anticancer Res , vol.24 , Issue.5 A , pp. 2705-2712
    • Kawano, T.1
  • 81
    • 34347334539 scopus 로고    scopus 로고
    • Depsipeptide (FK228) preferentially induces apoptosis in BCR/ABL-expressing cell lines and cells from patients with chronic myelogenous leukemia in blast crisis
    • DOI 10.1089/scd.2007.9994
    • S Okabe, et al. 2007 Depsipeptide (FK228) preferentially induces apoptosis in BCR/ABL-expressing cell lines and cells from patients with chronic myelogenous leukemia in blast crisis Stem Cells Dev 16 3 503 514 1:CAS:528:DC%2BD2sXnt1Wltr8%3D 10.1089/scd.2007.9994 17610380 (Pubitemid 47016235)
    • (2007) Stem Cells and Development , vol.16 , Issue.3 , pp. 503-514
    • Okabe, S.1    Tauchi, T.2    Nakajima, A.3    Sashida, G.4    Gotoh, A.5    Broxmeyer, H.E.6    Ohyashiki, J.H.7    Ohyashiki, K.8
  • 82
    • 67649509589 scopus 로고    scopus 로고
    • Anti-leukemic activity of valproic acid and imatinib mesylate on human Ph+ALL and CML cells in vitro
    • 1:CAS:528:DC%2BD1MXos1yiu7c%3D 10.1111/j.1600-0609.2009.01242.x 19226363
    • B Kircher, et al. 2009 Anti-leukemic activity of valproic acid and imatinib mesylate on human Ph+ALL and CML cells in vitro Eur J Haematol 83 1 48 56 1:CAS:528:DC%2BD1MXos1yiu7c%3D 10.1111/j.1600-0609.2009.01242.x 19226363
    • (2009) Eur J Haematol , vol.83 , Issue.1 , pp. 48-56
    • Kircher, B.1
  • 83
    • 33751244824 scopus 로고    scopus 로고
    • The proteomic study of sodium butyrate antiproliferative/ cytodifferentiation effects on K562 cells
    • DOI 10.1016/j.bcmd.2006.08.001, PII S1079979606001641
    • D Grebenova, et al. 2006 The proteomic study of sodium butyrate antiproliferative/cytodifferentiation effects on K562 cells Blood Cells Mol Dis 37 3 210 217 1:CAS:528:DC%2BD28Xht1CisL7K 10.1016/j.bcmd.2006.08.001 16978890 (Pubitemid 44781085)
    • (2006) Blood Cells, Molecules, and Diseases , vol.37 , Issue.3 , pp. 210-217
    • Grebenova, D.1    Kuzelova, K.2    Pluskalova, M.3    Peslova, G.4    Halada, P.5    Hrkal, Z.6
  • 84
    • 34249994385 scopus 로고    scopus 로고
    • Pivanex, a histone deacetylase inhibitor, induces changes in BCR-ABL expression and when combined with STI571, acts synergistically in a chronic myelocytic leukemia cell line
    • 1:CAS:528:DC%2BD2sXmtlamtrw%3D 10.1016/j.leukres.2006.12.015 17267032
    • E Rabizadeh, et al. 2007 Pivanex, a histone deacetylase inhibitor, induces changes in BCR-ABL expression and when combined with STI571, acts synergistically in a chronic myelocytic leukemia cell line Leuk Res 31 8 1115 1123 1:CAS:528:DC%2BD2sXmtlamtrw%3D 10.1016/j.leukres.2006.12.015 17267032
    • (2007) Leuk Res , vol.31 , Issue.8 , pp. 1115-1123
    • Rabizadeh, E.1
  • 85
    • 77952105211 scopus 로고    scopus 로고
    • Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate
    • 10.1016/j.ccr.2010.03.011 20478526
    • B Zhang, et al. 2010 Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate Cancer Cell 17 5 427 442 10.1016/j.ccr.2010.03.011 20478526
    • (2010) Cancer Cell , vol.17 , Issue.5 , pp. 427-442
    • Zhang, B.1
  • 86
    • 0032474904 scopus 로고    scopus 로고
    • P21-induced cycle arrest in G1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage
    • 1:CAS:528:DyaK1cXks1ensbg%3D 10.1038/sj.onc.1201899 9692554
    • N Bissonnette, et al. 1998 p21-induced cycle arrest in G1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage Oncogene 16 26 3461 3469 1:CAS:528:DyaK1cXks1ensbg%3D 10.1038/sj.onc.1201899 9692554
    • (1998) Oncogene , vol.16 , Issue.26 , pp. 3461-3469
    • Bissonnette, N.1
  • 87
    • 0033521925 scopus 로고    scopus 로고
    • Caspase 3 inactivation to suppress Fas-mediated apoptosis: Identification of binding domain with p21 and ILP and inactivation machinery by p21
    • DOI 10.1038/sj.onc.1202409
    • A Suzuki, et al. 1999 Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21 Oncogene 18 5 1239 1244 1:CAS:528:DyaK1MXhsVyrt7Y%3D 10.1038/sj.onc.1202409 10022130 (Pubitemid 29085997)
    • (1999) Oncogene , vol.18 , Issue.5 , pp. 1239-1244
    • Suzuki, A.1    Tsutomi, Y.2    Miura, M.3    Akahane, K.4
  • 88
    • 0034671745 scopus 로고    scopus 로고
    • kip1 through the phosphatidylinositol 3-kinase/AKT pathway
    • DOI 10.1074/jbc.M007291200
    • F Gesbert, et al. 2000 BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway J Biol Chem 275 50 39223 39230 1:CAS:528: DC%2BD3cXptFSrs7o%3D 10.1074/jbc.M007291200 11010972 (Pubitemid 32058940)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.50 , pp. 39223-39230
    • Gesbert, F.1    Sellers, W.R.2    Signoretti, S.3    Loda, M.4    Griffin, J.D.5
  • 90
    • 52649133274 scopus 로고    scopus 로고
    • HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells
    • 1:CAS:528:DC%2BD1cXhtVylu7jI 10.1182/blood-2008-03-143644 18591380
    • R Rao, et al. 2008 HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells Blood 112 5 1886 1893 1:CAS:528:DC%2BD1cXhtVylu7jI 10.1182/blood-2008-03-143644 18591380
    • (2008) Blood , vol.112 , Issue.5 , pp. 1886-1893
    • Rao, R.1
  • 94
    • 48749118821 scopus 로고    scopus 로고
    • De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc
    • 1:CAS:528:DC%2BD1cXhtV2lsb3J 18636159
    • LG Wang, et al. 2008 De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc Int J Oncol 33 2 375 380 1:CAS:528:DC%2BD1cXhtV2lsb3J 18636159
    • (2008) Int J Oncol , vol.33 , Issue.2 , pp. 375-380
    • Wang, L.G.1
  • 98
    • 73949136283 scopus 로고    scopus 로고
    • Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells
    • 1:CAS:528:DC%2BD1MXhsF2gsb%2FI 10.1182/blood-2009-05-222133 19828702
    • Y Wang, et al. 2009 Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells Blood 114 24 5024 5033 1:CAS:528:DC%2BD1MXhsF2gsb%2FI 10.1182/blood-2009-05-222133 19828702
    • (2009) Blood , vol.114 , Issue.24 , pp. 5024-5033
    • Wang, Y.1
  • 99
    • 77957284593 scopus 로고    scopus 로고
    • Activity of oral panobinostat (LBH589) in patients with myelofibrosis
    • DJ DeAngelo A Spencer T Fischer, et al. 2009 Activity of oral panobinostat (LBH589) in patients with myelofibrosis Blood 114 2898
    • (2009) Blood , vol.114 , pp. 2898
    • Deangelo, D.J.1    Spencer, A.2    Fischer, T.3
  • 100
    • 77950917500 scopus 로고    scopus 로고
    • A phase i study of LBH589, a novel histone deacetylase inhibitor in patients with primary myelofibrosis (PMF) and post-polycythemia/essential thrombocythemia myelofibrosis (Post-PV/ET MF)
    • 10.1182/blood-2009-06-230037
    • J Mascareenhas X Wang A Rodriguez 2009 A phase I study of LBH589, a novel histone deacetylase inhibitor in patients with primary myelofibrosis (PMF) and post-polycythemia/essential thrombocythemia myelofibrosis (Post-PV/ET MF) Blood 114 308 10.1182/blood-2009-06-230037
    • (2009) Blood , vol.114 , pp. 308
    • Mascareenhas, J.1    Wang, X.2    Rodriguez, A.3
  • 101
    • 67349127967 scopus 로고    scopus 로고
    • Clinical efficacy of vorinostat in a patient with essential thrombocytosis and subsequent myelofibrosis
    • 10.1007/s00277-008-0640-3 19030859
    • J Lee 2009 Clinical efficacy of vorinostat in a patient with essential thrombocytosis and subsequent myelofibrosis Ann Hematol 88 7 699 700 10.1007/s00277-008-0640-3 19030859
    • (2009) Ann Hematol , vol.88 , Issue.7 , pp. 699-700
    • Lee, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.