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Volumn 147, Issue 4, 2009, Pages 495-506

Phospho-STAT5 and phospho-Akt expression in chronic myeloproliferative neoplasms

Author keywords

Akt; Myeloproliferative neoplasms; Phosphorylation; STAT5

Indexed keywords

JANUS KINASE 2; MONOCLONAL ANTIBODY; PHOSPHOPROTEIN; PROTEIN KINASE B; STAT5 PROTEIN; STEM CELL FACTOR; THROMBOPOIETIN RECEPTOR;

EID: 70350446987     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2009.07870.x     Document Type: Article
Times cited : (63)

References (49)
  • 1
    • 33846620183 scopus 로고    scopus 로고
    • Bone marrow phospho-STAT5 expression in non-CML chronic myeloproliferative disorders correlates with JAK2 V617F mutation and provides evidence of in vivo JAK2 activation
    • Aboudola, S., Murugensan, G., Szpurka, H., Ramsingh, G., Zhao, X., Prescott, N., Tubbs, R., Maciejewski, J. Hsi, E. (2007) Bone marrow phospho-STAT5 expression in non-CML chronic myeloproliferative disorders correlates with JAK2 V617F mutation and provides evidence of in vivo JAK2 activation. American Journal of Surgical Pathology, 31, 233 239.
    • (2007) American Journal of Surgical Pathology , vol.31 , pp. 233-239
    • Aboudola, S.1    Murugensan, G.2    Szpurka, H.3    Ramsingh, G.4    Zhao, X.5    Prescott, N.6    Tubbs, R.7    MacIejewski, J.8    Hsi, E.9
  • 4
    • 33947528089 scopus 로고    scopus 로고
    • B-, T-, and NK-cell lineage involvement in JAK2V617F-positive patients with idiopathic myelofibrosis
    • Bogani, C., Guglielmelli, P., Antonioli, E., Pancrazzi, A., Bosi, A. Vannucchi, A. (2007) B-, T-, and NK-cell lineage involvement in JAK2V617F-positive patients with idiopathic myelofibrosis. Haematologica, 92, 258 259.
    • (2007) Haematologica , vol.92 , pp. 258-259
    • Bogani, C.1    Guglielmelli, P.2    Antonioli, E.3    Pancrazzi, A.4    Bosi, A.5    Vannucchi, A.6
  • 6
    • 34948903802 scopus 로고    scopus 로고
    • Cytoplasmic localization of phosphorylated STAT5 in human acute myeloid leukemia is inversely correlated with Flt3-ITD
    • Bunting, K., Xie, X., Warshawsky, I. Hsi, E. (2007) Cytoplasmic localization of phosphorylated STAT5 in human acute myeloid leukemia is inversely correlated with Flt3-ITD. Blood, 110, 2775 2776.
    • (2007) Blood , vol.110 , pp. 2775-2776
    • Bunting, K.1    Xie, X.2    Warshawsky, I.3    Hsi, E.4
  • 9
    • 33748206336 scopus 로고    scopus 로고
    • Constitutive activation of STAT5 and Bcl-xL overexpression can induce endogenous erythroid colony formation in human primary cells
    • Garcon, L., Rivat, C., James, C., Lacout, C., Camara-Clayette, V., Ugo, V., Lecluse, Y., Bennaceur-Griscelli, A. Vainchenker, W. (2006) Constitutive activation of STAT5 and Bcl-xL overexpression can induce endogenous erythroid colony formation in human primary cells. Blood, 108, 1551 1554.
    • (2006) Blood , vol.108 , pp. 1551-1554
    • Garcon, L.1    Rivat, C.2    James, C.3    Lacout, C.4    Camara-Clayette, V.5    Ugo, V.6    Lecluse, Y.7    Bennaceur-Griscelli, A.8    Vainchenker, W.9
  • 10
    • 36148995898 scopus 로고    scopus 로고
    • Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders
    • Gery, S., Gueller, S., Chumakova, K., Kawamata, N., Liu, L. Koeffler, H. (2007) Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders. Blood, 110, 3360 3364.
    • (2007) Blood , vol.110 , pp. 3360-3364
    • Gery, S.1    Gueller, S.2    Chumakova, K.3    Kawamata, N.4    Liu, L.5    Koeffler, H.6
  • 11
    • 45049087999 scopus 로고    scopus 로고
    • Phospho-STAT5 expression pattern with the MPL W515L mutation is similar to that seen in chronic myeloproliferative disorders with JAK2 V617F
    • Gibson, S.E., Schade, A.E., Szpurka, H., Bak, B., Maciejewski, J.P. Hsi, E.D. (2008) Phospho-STAT5 expression pattern with the MPL W515L mutation is similar to that seen in chronic myeloproliferative disorders with JAK2 V617F. Human Pathology, 39, 1111 1114.
    • (2008) Human Pathology , vol.39 , pp. 1111-1114
    • Gibson, S.E.1    Schade, A.E.2    Szpurka, H.3    Bak, B.4    MacIejewski, J.P.5    Hsi, E.D.6
  • 12
    • 70350455622 scopus 로고    scopus 로고
    • Akt and STAT5 signalling proteins are phosphorylated in systemic mastocytosis: Immunocytochemical demonstration by double labelling
    • Grimwade, L., Happerfield, L., Bench, A.J. Erber, W.N. (2008) Akt and STAT5 signalling proteins are phosphorylated in systemic mastocytosis: immunocytochemical demonstration by double labelling. International Journal of Laboratory Hematology, 30 (Suppl.1 58 147.
    • (2008) International Journal of Laboratory Hematology , vol.30 , Issue.SUPPL. 1 , pp. 58-147
    • Grimwade, L.1    Happerfield, L.2    Bench, A.J.3    Erber, W.N.4
  • 15
    • 33750611344 scopus 로고    scopus 로고
    • Involvement of various hematopoietic-cell lineages by the JAK2V617F mutation in polycythemia vera
    • Ishii, T., Bruno, E., Hoffman, R. Xu, M. (2006) Involvement of various hematopoietic-cell lineages by the JAK2V617F mutation in polycythemia vera. Blood, 108, 3128 3134.
    • (2006) Blood , vol.108 , pp. 3128-3134
    • Ishii, T.1    Bruno, E.2    Hoffman, R.3    Xu, M.4
  • 17
    • 54349094747 scopus 로고    scopus 로고
    • Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis
    • Jones, A., Cross, N., White, H., Green, A. Scott, L. (2008) Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis. Haematologica, 93, 1560 1564.
    • (2008) Haematologica , vol.93 , pp. 1560-1564
    • Jones, A.1    Cross, N.2    White, H.3    Green, A.4    Scott, L.5
  • 18
    • 54149085320 scopus 로고    scopus 로고
    • JAK2 and MPL mutations in myeloproliferative neoplasms: Discovery and science
    • Kilpivaara, O. Levine, R. (2008) JAK2 and MPL mutations in myeloproliferative neoplasms: discovery and science. Leukemia, 20, 1813 1817.
    • (2008) Leukemia , vol.20 , pp. 1813-1817
    • Kilpivaara, O.1    Levine, R.2
  • 19
    • 54049107323 scopus 로고    scopus 로고
    • Aberrant signal transduction pathways in myeloproliferative neoplasms
    • Kota, J., Caceres, N. Constantinescu, S.N. (2008) Aberrant signal transduction pathways in myeloproliferative neoplasms. Leukemia, 20, 1828 1840.
    • (2008) Leukemia , vol.20 , pp. 1828-1840
    • Kota, J.1    Caceres, N.2    Constantinescu, S.N.3
  • 20
    • 27244432586 scopus 로고    scopus 로고
    • Mutation studies in CD3+, CD19+ and CD34+ cell fractions in myeloproliferative disorders with homozygous JAK2(V617F) in granulocytes
    • Lasho, T., Mesa, R., Gilliland, D. Tefferi, A. (2005) Mutation studies in CD3+, CD19+ and CD34+ cell fractions in myeloproliferative disorders with homozygous JAK2(V617F) in granulocytes. British Journal of Haematology, 130, 797 799.
    • (2005) British Journal of Haematology , vol.130 , pp. 797-799
    • Lasho, T.1    Mesa, R.2    Gilliland, D.3    Tefferi, A.4
  • 21
    • 55249095625 scopus 로고    scopus 로고
    • Myeloproliferative disorders
    • Levine, R.L. Gilliland, D.G. (2008) Myeloproliferative disorders. Blood, 112, 2190 2198.
    • (2008) Blood , vol.112 , pp. 2190-2198
    • Levine, R.L.1    Gilliland, D.G.2
  • 23
    • 34548240698 scopus 로고    scopus 로고
    • Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders
    • Levine, R.L., Pardanani, A., Tefferi, A. Gilliland, D.G. (2007) Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders. Nature Reviews: Cancer, 7, 673 683.
    • (2007) Nature Reviews: Cancer , vol.7 , pp. 673-683
    • Levine, R.L.1    Pardanani, A.2    Tefferi, A.3    Gilliland, D.G.4
  • 29
    • 34548152255 scopus 로고    scopus 로고
    • Amendment to the guideline for diagnosis and investigation of polycythaemia/erythrocytosis
    • On behalf of the National Cancer Research Institute, Myeloproliferative Disorder Subgroup. and. On behalf of the British Committee for Standards in Haematology
    • McMullin, M., Reilly, J.T., Campbell, P., Bareford, D., Green, A.R., Harrison, C. Conneally, E., On behalf of the National Cancer Research Institute, Myeloproliferative Disorder Subgroup and Ryan, K., On behalf of the British Committee for Standards in Haematology (2007) Amendment to the guideline for diagnosis and investigation of polycythaemia/erythrocytosis. British Journal of Haematology, 138, 821 823.
    • (2007) British Journal of Haematology , vol.138 , pp. 821-823
    • McMullin, M.1    Reilly, J.T.2    Campbell, P.3    Bareford, D.4    Green, A.R.5    Harrison, C.6    Conneally, E.7    Ryan, K.8
  • 30
    • 0033618371 scopus 로고    scopus 로고
    • Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines
    • Nakatani, K., Thompson, D.A., Barthel, A., Sakaue, H., Liu, W., Weigel, R.J. Roth, R.A. (1999) Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. Journal of Biological Chemistry, 274, 21528 21532.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 21528-21532
    • Nakatani, K.1    Thompson, D.A.2    Barthel, A.3    Sakaue, H.4    Liu, W.5    Weigel, R.J.6    Roth, R.A.7
  • 31
    • 0036185848 scopus 로고    scopus 로고
    • The protein kinase B/Akt signalling pathway in human malignancy
    • Nicholson, K.M. Anderson, N.G. (2002) The protein kinase B/Akt signalling pathway in human malignancy. Cellular Signalling, 14, 381 395.
    • (2002) Cellular Signalling , vol.14 , pp. 381-395
    • Nicholson, K.M.1    Anderson, N.G.2
  • 32
    • 34548128326 scopus 로고    scopus 로고
    • Prevalence and clinicopathologic correlates of JAK2 exon 12 mutations in JAK2V617F-negative polycythemia vera
    • Pardanani, A., Lasho, T., Fincke, C., Hanson, C. Tefferi, A. (2007) Prevalence and clinicopathologic correlates of JAK2 exon 12 mutations in JAK2V617F-negative polycythemia vera. Leukemia, 21, 1960 1963.
    • (2007) Leukemia , vol.21 , pp. 1960-1963
    • Pardanani, A.1    Lasho, T.2    Fincke, C.3    Hanson, C.4    Tefferi, A.5
  • 33
  • 34
    • 0026770248 scopus 로고
    • Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
    • Schindler, C., Shuai, K., Prezioso, V. Darnell, J. (1992) Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science, 257, 809 813.
    • (1992) Science , vol.257 , pp. 809-813
    • Schindler, C.1    Shuai, K.2    Prezioso, V.3    Darnell, J.4
  • 37
    • 0028349904 scopus 로고
    • Interferon activation of the transcription factor STAT91 involves dimerisation through SH2-phosphotyroysl pepride interactions
    • Shaui, K., Horvath, C., Tsai Huang, L., Qureshi, S., Cowburn, D. Darnell, J. (1994) Interferon activation of the transcription factor STAT91 involves dimerisation through SH2-phosphotyroysl pepride interactions. Cell, 76, 821 828.
    • (1994) Cell , vol.76 , pp. 821-828
    • Shaui, K.1    Horvath, C.2    Tsai Huang, L.3    Qureshi, S.4    Cowburn, D.5    Darnell, J.6
  • 39
    • 0042591430 scopus 로고    scopus 로고
    • Phosphatidylinositol 3 kinase is required for growth of mast cells expressing kit catalytic domain mutant
    • Shivakrupa, R., Bernstein, A., Watring, N. Linnekin, D. (2003) Phosphatidylinositol 3 kinase is required for growth of mast cells expressing kit catalytic domain mutant. Cancer Research, 63, 4412 4419.
    • (2003) Cancer Research , vol.63 , pp. 4412-4419
    • Shivakrupa, R.1    Bernstein, A.2    Watring, N.3    Linnekin, D.4
  • 40
    • 33745473836 scopus 로고    scopus 로고
    • Combined locked nucleic acid and molecular beacon technologies for sensitive detection of the JAK2V617F somatic single-base sequence variant
    • Sidon, P., Heimann, P., Lambert, F., Dessars, B., Robin, V. El Housni, H. (2006) Combined locked nucleic acid and molecular beacon technologies for sensitive detection of the JAK2V617F somatic single-base sequence variant. Clinical Chemistry, 52, 1436 1438.
    • (2006) Clinical Chemistry , vol.52 , pp. 1436-1438
    • Sidon, P.1    Heimann, P.2    Lambert, F.3    Dessars, B.4    Robin, V.5    El Housni, H.6
  • 42
    • 0037238684 scopus 로고    scopus 로고
    • Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogene
    • Sundstrom, M., Vliagoftis, H., Karlberg, P., Butterfield, J.H., Nilsson, K., Metcalfe, D.D. Nilsson, G. (2003) Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogene. Immunology, 108, 89 97.
    • (2003) Immunology , vol.108 , pp. 89-97
    • Sundstrom, M.1    Vliagoftis, H.2    Karlberg, P.3    Butterfield, J.H.4    Nilsson, K.5    Metcalfe, D.D.6    Nilsson, G.7
  • 44
    • 8744225522 scopus 로고    scopus 로고
    • Demonstration that mast cells, T cells, and B cells bearing the activating kit mutation D816V occur in clusters within the marrow of patients with mastocytosis
    • Taylor, M., Sehgal, D., Raffeld, M., Obiakor, H., Akin, C., Mage, R. Metcalfe, D. (2004) Demonstration that mast cells, T cells, and B cells bearing the activating kit mutation D816V occur in clusters within the marrow of patients with mastocytosis. The Journal of Molecular Diagnostics, 6, 335 342.
    • (2004) The Journal of Molecular Diagnostics , vol.6 , pp. 335-342
    • Taylor, M.1    Sehgal, D.2    Raffeld, M.3    Obiakor, H.4    Akin, C.5    Mage, R.6    Metcalfe, D.7
  • 45
    • 34347385613 scopus 로고    scopus 로고
    • Different STAT-3 and STAT-5 phosphorylation discriminates among Ph-negative chronic myeloproliferative diseases and is independent of the V617F JAK-2 mutation
    • Teofili, L., Martini, M., Cenci, T., Petrucci, G., Torti, L., Storti, S., Guidi, F., Leone, G. Larocca, L.M. (2007) Different STAT-3 and STAT-5 phosphorylation discriminates among Ph-negative chronic myeloproliferative diseases and is independent of the V617F JAK-2 mutation. Blood, 110, 354 359.
    • (2007) Blood , vol.110 , pp. 354-359
    • Teofili, L.1    Martini, M.2    Cenci, T.3    Petrucci, G.4    Torti, L.5    Storti, S.6    Guidi, F.7    Leone, G.8    Larocca, L.M.9
  • 46
    • 34548559124 scopus 로고    scopus 로고
    • Detection of phospho-STAT5 in mast cells: A reliable phenotypic marker of systemic mast cell disease that reflects constitutive tyrosine kinase activation
    • Toro, T., Hsieh, F.H., Bodo, J., Dong, H.Y. Hsi, E.D. (2007) Detection of phospho-STAT5 in mast cells: a reliable phenotypic marker of systemic mast cell disease that reflects constitutive tyrosine kinase activation. British Journal of Haematology, 139, 31 40.
    • (2007) British Journal of Haematology , vol.139 , pp. 31-40
    • Toro, T.1    Hsieh, F.H.2    Bodo, J.3    Dong, H.Y.4    Hsi, E.D.5
  • 48
    • 33646414171 scopus 로고    scopus 로고
    • Increased death receptor resistance and FLIPshort expression in polycythemia vera erythroid precursor cells
    • Zeuner, A., Pedini, F., Signore, M., Ruscio, G., Messina, C., Tafuri, A., Girelli, G., Peschle, C. De Maria, R. (2006) Increased death receptor resistance and FLIPshort expression in polycythemia vera erythroid precursor cells. Blood, 107, 3495 3502.
    • (2006) Blood , vol.107 , pp. 3495-3502
    • Zeuner, A.1    Pedini, F.2    Signore, M.3    Ruscio, G.4    Messina, C.5    Tafuri, A.6    Girelli, G.7    Peschle, C.8    De Maria, R.9


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