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Volumn 734, Issue , 2013, Pages 1-22

Progress and trends in complement therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHYLATOXIN; ARC 1905; BACTERIAL PROTEIN; BACTERIAL VACCINE; BCX 1470; CD59 ANTIGEN; CHEMOTAXIS INHIBITOR; CHEMOTAXIS INHIBITOR PROTEIN OF STAPHYLOCOCCUS AUREUS; COBROTOXIN; COMPLEMENT; COMPLEMENT COMPONENT C1S INHIBITOR; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C5; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT INHIBITOR; COMPSTATIN; ECULIZUMAB; MIROCOCEPT; NOX D19; OPSONIN; ORNITHODOROS MOUBATA COMPLEMENT INHIBITOR; PROPERDIN; PROTEINASE INHIBITOR; SMALL INTERFERING RNA; TA 106; UNCLASSIFIED DRUG; VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN; ANTIINFLAMMATORY AGENT; NEW DRUG;

EID: 84934440020     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-4118-2_1     Document Type: Conference Paper
Times cited : (100)

References (167)
  • 1
    • 84924252450 scopus 로고    scopus 로고
    • Viral complement regulators: The expert mimicking swindlers
    • Ahmad M, Pyaram K, Mullick J, Sahu A (2007) Viral complement regulators: the expert mimicking swindlers. Indian J Biochem Biophys 44(5):331-3433
    • (2007) Indian J Biochem Biophys , vol.44 , Issue.5 , pp. 331-3433
    • Ahmad, M.1    Pyaram, K.2    Mullick, J.3    Sahu, A.4
  • 5
    • 78149477844 scopus 로고    scopus 로고
    • Molecular intercommunication between the complement and coagulation systems
    • Amara U, Flierl MA, Rittirsch D, Klos A, Chen H, Acker B et al (2010) Molecular intercommunication between the complement and coagulation systems. J Immunol 185(9):5628-56366
    • (2010) J Immunol , vol.185 , Issue.9 , pp. 5628-56366
    • Amara, U.1    Flierl, M.A.2    Rittirsch, D.3    Klos, A.4    Chen, H.5    Acker, B.6
  • 6
    • 77249147331 scopus 로고    scopus 로고
    • The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
    • Anderson DH, Radeke MJ, Gallo NB, Chapin EA, Johnson PT, Curletti CR et al (2010) The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Prog Retin Eye Res 29(2):95-1122
    • (2010) Prog Retin Eye Res , vol.29 , Issue.2 , pp. 95-1122
    • Anderson, D.H.1    Radeke, M.J.2    Gallo, N.B.3    Chapin, E.A.4    Johnson, P.T.5    Curletti, C.R.6
  • 7
    • 34548213567 scopus 로고    scopus 로고
    • Deciphering complement mechanisms: The contributions of structural biology
    • Arlaud GJ, Barlow PN, Gaboriaud C, Gros P, Narayana SV (2007) Deciphering complement mechanisms: the contributions of structural biology. Mol Immunol 44(16):3809-38222
    • (2007) Mol Immunol , vol.44 , Issue.16 , pp. 3809-38222
    • Arlaud, G.J.1    Barlow, P.N.2    Gaboriaud, C.3    Gros, P.4    Narayana, S.V.5
  • 9
    • 75149162850 scopus 로고    scopus 로고
    • Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice
    • Banda NK, Levitt B, Glogowska MJ, Thurman JM, Takahashi K, Stahl GL et al (2009) Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice. J Immunol 183(9):5928-59377
    • (2009) J Immunol , vol.183 , Issue.9 , pp. 5928-59377
    • Banda, N.K.1    Levitt, B.2    Glogowska, M.J.3    Thurman, J.M.4    Takahashi, K.5    Stahl, G.L.6
  • 10
    • 84859366157 scopus 로고    scopus 로고
    • Role of complement and perspectives for intervention in ischemia-reperfusion damage
    • Banz Y, Rieben R (2012) Role of complement and perspectives for intervention in ischemia-reperfusion damage. Ann Med 44(3):205-2177
    • (2012) Ann Med , vol.44 , Issue.3 , pp. 205-2177
    • Banz, Y.1    Rieben, R.2
  • 11
    • 35548936851 scopus 로고    scopus 로고
    • Attenuation of myocardial reperfusion injury in pigs by Mirococept, a membrane-targeted complement inhibitor derived from human CR1
    • Banz Y, Hess OM, Robson SC, Csizmadia E, Mettler D, Meier P et al (2007) Attenuation of myocardial reperfusion injury in pigs by Mirococept, a membrane-targeted complement inhibitor derived from human CR1. Cardiovasc Res 76(3):482-4933
    • (2007) Cardiovasc Res , vol.76 , Issue.3 , pp. 482-4933
    • Banz, Y.1    Hess, O.M.2    Robson, S.C.3    Csizmadia, E.4    Mettler, D.5    Meier, P.6
  • 12
    • 80555154787 scopus 로고    scopus 로고
    • Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans
    • Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Lissina O, Lambris JD et al (2011) Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans. J Immunol 187(9):4913-49199
    • (2011) J Immunol , vol.187 , Issue.9 , pp. 4913-49199
    • Barratt-Due, A.1    Thorgersen, E.B.2    Lindstad, J.K.3    Pharo, A.4    Lissina, O.5    Lambris, J.D.6
  • 13
    • 56449121919 scopus 로고    scopus 로고
    • C1, MBL-MASPs and C1-inhibitor: Novel approaches for targeting complement-mediated in flammation
    • Beinrohr L, Dobo J, Zavodszky P, Gal P (2008) C1, MBL-MASPs and C1-inhibitor: novel approaches for targeting complement-mediated in flammation. Trends Mol Med 14(12):511-5211
    • (2008) Trends Mol Med , vol.14 , Issue.12 , pp. 511-5211
    • Beinrohr, L.1    Dobo, J.2    Zavodszky, P.3    Gal, P.4
  • 14
    • 0016142804 scopus 로고
    • Complement deposition in the kidney
    • Berger J (1974) Complement deposition in the kidney. Adv Nephrol Necker Hosp 4:37-488
    • (1974) Adv Nephrol Necker Hosp , vol.4 , pp. 37-488
    • Berger, J.1
  • 15
    • 79959715005 scopus 로고    scopus 로고
    • Proteomic biomarker discovery: It's more than just mass spectrometry
    • Blonder J, Issaq HJ, Veenstra TD (2011) Proteomic biomarker discovery: it's more than just mass spectrometry. Electrophoresis 32(13):1541-15488
    • (2011) Electrophoresis , vol.32 , Issue.13 , pp. 1541-15488
    • Blonder, J.1    Issaq, H.J.2    Veenstra, T.D.3
  • 16
    • 77958590255 scopus 로고    scopus 로고
    • Recombinant membrane-targeted form of CD59 inhibits the growth of choroidal neovascular complex in mice
    • Bora NS, Jha P, Lyzogubov VV, Kaliappan S, Liu J, Tytarenko RG et al (2010) Recombinant membrane-targeted form of CD59 inhibits the growth of choroidal neovascular complex in mice. J Biol Chem 285(44):33826-338333
    • (2010) J Biol Chem , vol.285 , Issue.44 , pp. 33826-338333
    • Bora, N.S.1    Jha, P.2    Lyzogubov, V.V.3    Kaliappan, S.4    Liu, J.5    Tytarenko, R.G.6
  • 17
    • 80555154767 scopus 로고    scopus 로고
    • Role of C3, C5 and anaphylatoxin receptors in acute lung injury and in sepsis
    • Bosmann M, Ward PA (2012) Role of C3, C5 and anaphylatoxin receptors in acute lung injury and in sepsis. Adv Exp Med Biol 946:147-1599
    • (2012) Adv Exp Med Biol , vol.946 , pp. 147-1599
    • Bosmann, M.1    Ward, P.A.2
  • 18
    • 57349180532 scopus 로고    scopus 로고
    • Identi fication and characterization of NDT 9513727 [N, N-bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-imidazole-5-methanam ine], a novel, orally bioavailable C5a receptor inverse agonist
    • Brodbeck RM, Cortright DN, Kieltyka AP, Yu J, Baltazar CO, Buck ME et al (2008) Identi fication and characterization of NDT 9513727 [N, N-bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-imidazole-5-methanam ine], a novel, orally bioavailable C5a receptor inverse agonist. J Pharmacol Exp Ther 327(3):898-9099
    • (2008) J Pharmacol Exp Ther , vol.327 , Issue.3 , pp. 898-9099
    • Brodbeck, R.M.1    Cortright, D.N.2    Kieltyka, A.P.3    Yu, J.4    Baltazar, C.O.5    Buck, M.E.6
  • 19
    • 34247552176 scopus 로고    scopus 로고
    • Mechanisms of disease: The complement system in renal injury - New ways of looking at an old foe
    • Brown KM, Sacks SH, Sheerin NS (2007) Mechanisms of disease: the complement system in renal injury - new ways of looking at an old foe. Nat Clin Pract Nephrol 3(5):277-2866
    • (2007) Nat Clin Pract Nephrol , vol.3 , Issue.5 , pp. 277-2866
    • Brown, K.M.1    Sacks, S.H.2    Sheerin, N.S.3
  • 20
    • 80052162537 scopus 로고    scopus 로고
    • Complement in health and disease
    • Carroll MV, Sim RB (2011) Complement in health and disease. Adv Drug Deliv Rev 63(12):965-9755
    • (2011) Adv Drug Deliv Rev , vol.63 , Issue.12 , pp. 965-9755
    • Carroll, M.V.1    Sim, R.B.2
  • 21
    • 79955721853 scopus 로고    scopus 로고
    • A non membrane-targeted human soluble CD59 attenuates choroidal neovascularization in a model of age related macular degeneration
    • Cashman SM, Ramo K, Kumar-Singh R (2011) A non membrane-targeted human soluble CD59 attenuates choroidal neovascularization in a model of age related macular degeneration. PLoS One 6(4):e190788
    • (2011) PLoS One , vol.6 , Issue.4
    • Cashman, S.M.1    Ramo, K.2    Kumar-Singh, R.3
  • 22
    • 34548566416 scopus 로고    scopus 로고
    • The anti-inflammatory activities of Staphylococcus aureus
    • Chavakis T, Preissner KT, Herrmann M (2007) The anti-inflammatory activities of Staphylococcus aureus . Trends Immunol 28(9):408-4188
    • (2007) Trends Immunol , vol.28 , Issue.9 , pp. 408-4188
    • Chavakis, T.1    Preissner, K.T.2    Herrmann, M.3
  • 23
    • 81155162428 scopus 로고    scopus 로고
    • Complement inhibition enables renal allograft accommodation and long-term engraftment in presensitized nonhuman primates
    • Chen Song S, Zhong S, Xiang Y, Li JH, Guo H, Wang WY et al (2011) Complement inhibition enables renal allograft accommodation and long-term engraftment in presensitized nonhuman primates. Am J Transplant 11(10):2057-20666
    • (2011) Am J Transplant , vol.11 , Issue.10 , pp. 2057-20666
    • Chen Song, S.1    Zhong, S.2    Xiang, Y.3    Li, J.H.4    Guo, H.5    Wang, W.Y.6
  • 24
    • 78049233405 scopus 로고    scopus 로고
    • Allosteric inhibition of complement function by a staphylococcal immune evasion protein
    • Chen H, Ricklin D, Hammel M, Garcia BL, McWhorter WJ, Sfyroera G et al (2010) Allosteric inhibition of complement function by a staphylococcal immune evasion protein. Proc Natl Acad Sci USA 107(41):17621-176266
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.41 , pp. 17621-176266
    • Chen, H.1    Ricklin, D.2    Hammel, M.3    Garcia, B.L.4    McWhorter, W.J.5    Sfyroera, G.6
  • 25
    • 79952118241 scopus 로고    scopus 로고
    • Suppression of drusen formation by compstatin, a peptide inhibitor of complement C3 activation, on cynomolgus monkey with early-onset macular degeneration
    • Chi ZL, Yoshida T, Lambris JD, Iwata T (2010) Suppression of drusen formation by compstatin, a peptide inhibitor of complement C3 activation, on cynomolgus monkey with early-onset macular degeneration. Adv Exp Med Biol 703:127-1355
    • (2010) Adv Exp Med Biol , vol.703 , pp. 127-1355
    • Chi, Z.L.1    Yoshida, T.2    Lambris, J.D.3    Iwata, T.4
  • 26
    • 80555133248 scopus 로고    scopus 로고
    • Differential effect of inhibiting MD-2 and CD14 on LPS-versus whole E. coli bacteria-induced cytokine responses in human blood
    • Christiansen D, Brekke OL, Stenvik J, Lambris JD, Espevik T, Mollnes TE (2012) Differential effect of inhibiting MD-2 and CD14 on LPS-versus whole E. coli bacteria-induced cytokine responses in human blood. Adv Exp Med Biol 946:237-2511
    • (2012) Adv Exp Med Biol , vol.946 , pp. 237-2511
    • Christiansen, D.1    Brekke, O.L.2    Stenvik, J.3    Lambris, J.D.4    Espevik, T.5    Mollnes, T.E.6
  • 27
    • 78149481863 scopus 로고    scopus 로고
    • C1inhibitor, a multi-functional serine protease inhibitor
    • Davis AE 3rd, Lu F, Mejia P (2010) C1inhibitor, a multi-functional serine protease inhibitor. Thromb Haemost 104(5):886-8933
    • (2010) Thromb Haemost , vol.104 , Issue.5 , pp. 886-8933
    • Davis III, A.E.1    Lu, F.2    Mejia, P.3
  • 28
    • 79958823141 scopus 로고    scopus 로고
    • Disease-causing mutations in genes of the complement system
    • Degn SE, Jensenius JC, Thiel S (2011) Disease-causing mutations in genes of the complement system. Am J Hum Gen 88(6):689-7055
    • (2011) Am J Hum Gen , vol.88 , Issue.6 , pp. 689-7055
    • Degn, S.E.1    Jensenius, J.C.2    Thiel, S.3
  • 29
    • 52949136616 scopus 로고    scopus 로고
    • FDA report: Eculizumab (Soliris) for the treatment of patients with paroxysmal nocturnal hemoglobinuria
    • Dmytrijuk A, Robie-Suh K, Cohen MH, Rieves D, Weiss K, Pazdur R (2008) FDA report: eculizumab (Soliris) for the treatment of patients with paroxysmal nocturnal hemoglobinuria. Oncologist 13(9):993-10000
    • (2008) Oncologist , vol.13 , Issue.9 , pp. 993-10000
    • Dmytrijuk, A.1    Robie-Suh, K.2    Cohen, M.H.3    Rieves, D.4    Weiss, K.5    Pazdur, R.6
  • 30
    • 80052157101 scopus 로고    scopus 로고
    • Innate immunity activation on biomaterial surfaces: A mechanistic model and coping strategies
    • Ekdahl KN, Lambris JD, Elwing H, Ricklin D, Nilsson PH, Teramura Y et al (2011) Innate immunity activation on biomaterial surfaces: a mechanistic model and coping strategies. Adv Drug Deliv Rev 63(12):1042-10500
    • (2011) Adv Drug Deliv Rev , vol.63 , Issue.12 , pp. 1042-10500
    • Ekdahl, K.N.1    Lambris, J.D.2    Elwing, H.3    Ricklin, D.4    Nilsson, P.H.5    Teramura, Y.6
  • 31
    • 34250649678 scopus 로고    scopus 로고
    • Complement C3 and C4 in plasma and incidence of myocardial infarction and stroke: A population-based cohort study
    • Engstrom G, Hedblad B, Janzon L, Lindgarde F (2007) Complement C3 and C4 in plasma and incidence of myocardial infarction and stroke: a population-based cohort study. Eur J Cardiovasc Prev Rehabil 14(3):392-3977
    • (2007) Eur J Cardiovasc Prev Rehabil , vol.14 , Issue.3 , pp. 392-3977
    • Engstrom, G.1    Hedblad, B.2    Janzon, L.3    Lindgarde, F.4
  • 32
    • 69249152289 scopus 로고    scopus 로고
    • Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease
    • Fonseca MI, Ager RR, Chu SH, Yazan O, Sanderson SD, LaFerla FM et al (2009) Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. J Immunol 183(2):1375-13833
    • (2009) J Immunol , vol.183 , Issue.2 , pp. 1375-13833
    • Fonseca, M.I.1    Ager, R.R.2    Chu, S.H.3    Yazan, O.4    Sanderson, S.D.5    Laferla, F.M.6
  • 33
    • 78651377751 scopus 로고    scopus 로고
    • Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease
    • Fonseca MI, Chu SH, Berci AM, Benoit ME, Peters DG, Kimura Y et al (2011) Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease. J Neuroin flammation 8(1):44
    • (2011) J Neuroin Flammation , vol.8 , Issue.1 , pp. 44
    • Fonseca, M.I.1    Chu, S.H.2    Berci, A.M.3    Benoit, M.E.4    Peters, D.G.5    Kimura, Y.6
  • 34
    • 78650638514 scopus 로고    scopus 로고
    • Structures of C3b in complex with factors B and D give insight into complement convertase formation
    • Forneris F, Ricklin D, Wu J, Tzekou A, Wallace RS, Lambris JD et al (2010) Structures of C3b in complex with factors B and D give insight into complement convertase formation. Science 330(6012):1816-18200
    • (2010) Science , vol.330 , Issue.6012 , pp. 1816-18200
    • Forneris, F.1    Ricklin, D.2    Wu, J.3    Tzekou, A.4    Wallace, R.S.5    Lambris, J.D.6
  • 35
    • 1542781737 scopus 로고    scopus 로고
    • Generation of a recombinant, membrane-targeted form of the complement regulator CD59: Activity in vitro and in vivo
    • Fraser DA, Harris CL, Williams AS, Mizuno M, Gallagher S, Smith RA et al (2003) Generation of a recombinant, membrane-targeted form of the complement regulator CD59: activity in vitro and in vivo. J Biol Chem 278(49):48921-489277
    • (2003) J Biol Chem , vol.278 , Issue.49 , pp. 48921-489277
    • Fraser, D.A.1    Harris, C.L.2    Williams, A.S.3    Mizuno, M.4    Gallagher, S.5    Smith, R.A.6
  • 36
    • 80055082640 scopus 로고    scopus 로고
    • Design and development of TT30, a novel C3d-targeted C3/C5 convertase inhibitor for treatment of human complement alternative pathwaymediated diseases
    • Fridkis-Hareli M, Storek M, Mazsaroff I, Risitano AM, Lundberg AS, Horvath CJ et al (2011) Design and development of TT30, a novel C3d-targeted C3/C5 convertase inhibitor for treatment of human complement alternative pathwaymediated diseases. Blood 118(17):4705-47133
    • (2011) Blood , vol.118 , Issue.17 , pp. 4705-47133
    • Fridkis-Hareli, M.1    Storek, M.2    Mazsaroff, I.3    Risitano, A.M.4    Lundberg, A.S.5    Horvath, C.J.6
  • 37
    • 79952119111 scopus 로고    scopus 로고
    • Complement depletion with humanized cobra venom factor in a mouse model of age-related macular degeneration
    • Fritzinger DC, Dean R, Meschter C, Wong K, Halter R, Borlak J et al (2010) Complement depletion with humanized cobra venom factor in a mouse model of age-related macular degeneration. Adv Exp Med Biol 703:151-1622
    • (2010) Adv Exp Med Biol , vol.703 , pp. 151-1622
    • Fritzinger, D.C.1    Dean, R.2    Meschter, C.3    Wong, K.4    Halter, R.5    Borlak, J.6
  • 38
    • 2442487762 scopus 로고    scopus 로고
    • Inactivation of C5a anaphylatoxin by a peptide that is complementary to a region of C5a
    • Fujita E, Farkas I, Campbell W, Baranyi L, Okada H, Okada N (2004) Inactivation of C5a anaphylatoxin by a peptide that is complementary to a region of C5a. J Immunol 172(10):6382-63877
    • (2004) J Immunol , vol.172 , Issue.10 , pp. 6382-63877
    • Fujita, E.1    Farkas, I.2    Campbell, W.3    Baranyi, L.4    Okada, H.5    Okada, N.6
  • 39
    • 0030898227 scopus 로고    scopus 로고
    • Soluble complement receptor type 1 and antithrombin-III combination therapy prolongs xenograft survival: The role of thrombin and prostacyclin in hyperacute rejection
    • Fujiwara I, Nakajima H, Akioka K, Matsuda T, Oka T (1997) Soluble complement receptor type 1 and antithrombin-III combination therapy prolongs xenograft survival: the role of thrombin and prostacyclin in hyperacute rejection. Transplant Proc 29(1-2):935-9377
    • (1997) Transplant Proc , vol.29 , Issue.1-2 , pp. 935-9377
    • Fujiwara, I.1    Nakajima, H.2    Akioka, K.3    Matsuda, T.4    Oka, T.5
  • 40
    • 77955485116 scopus 로고    scopus 로고
    • Cutting edge: C1q binds deoxyribose and heparan sulfate through neighboring sites of its recognition domain
    • Garlatti V, Chouquet A, Lunardi T, Vives R, Paidassi H, Lortat-Jacob H et al (2010) Cutting edge: C1q binds deoxyribose and heparan sulfate through neighboring sites of its recognition domain. J Immunol 185(2):808-8122
    • (2010) J Immunol , vol.185 , Issue.2 , pp. 808-8122
    • Garlatti, V.1    Chouquet, A.2    Lunardi, T.3    Vives, R.4    Paidassi, H.5    Lortat-Jacob, H.6
  • 41
    • 80455162357 scopus 로고    scopus 로고
    • RILYd4, a human CD59 inhibitor, enhances complementdependent cytotoxicity of ofatumumab against rituximab-resistant B-cell lymphoma cells and chronic lymphocytic leukemia
    • Ge X, Wu L, Hu W, Fernandes S, Wang C, Li X et al (2011) rILYd4, a human CD59 inhibitor, enhances complementdependent cytotoxicity of ofatumumab against rituximab-resistant B-cell lymphoma cells and chronic lymphocytic leukemia. Clin Cancer Res 17(21):6702-67111
    • (2011) Clin Cancer Res , vol.17 , Issue.21 , pp. 6702-67111
    • Ge, X.1    Wu, L.2    Hu, W.3    Fernandes, S.4    Wang, C.5    Li, X.6
  • 42
    • 84862833647 scopus 로고    scopus 로고
    • Inhibition of membrane complement inhibitor expression (CD46, CD55, CD59) by siRNA sensitizes tumor cells to complement attack in vitro
    • Geis N, Zell S, Rutz R, Li W, Giese T, Mamidi S et al (2010) Inhibition of membrane complement inhibitor expression (CD46, CD55, CD59) by siRNA sensitizes tumor cells to complement attack in vitro. Curr Cancer Drug Targets 10(8):922-9311
    • (2010) Curr Cancer Drug Targets , vol.10 , Issue.8 , pp. 922-9311
    • Geis, N.1    Zell, S.2    Rutz, R.3    Li, W.4    Giese, T.5    Mamidi, S.6
  • 43
    • 77949487756 scopus 로고    scopus 로고
    • Vaccinia virus complement control protein (VCP) improves kidney structure and function following ischemia/reperfusion injury in rats
    • Ghebremariam YT, Engelbrecht G, Tyler M, Lotz Z, Govender D, Kotwal GJ et al (2010) Vaccinia virus complement control protein (VCP) improves kidney structure and function following ischemia/reperfusion injury in rats. J Surg Res 159(2):747-7544
    • (2010) J Surg Res , vol.159 , Issue.2 , pp. 747-7544
    • Ghebremariam, Y.T.1    Engelbrecht, G.2    Tyler, M.3    Lotz, Z.4    Govender, D.5    Kotwal, G.J.6
  • 44
    • 84855275016 scopus 로고    scopus 로고
    • Variation in complement component C11 inhibitor in age-related macular degeneration
    • Gibson J, Hakobyan S, Cree AJ, Collins A, Harris CL, Ennis S et al (2012) Variation in complement component C11 inhibitor in age-related macular degeneration. Immunobiology 217(2):251-2555
    • (2012) Immunobiology , vol.217 , Issue.2 , pp. 251-2555
    • Gibson, J.1    Hakobyan, S.2    Cree, A.J.3    Collins, A.4    Harris, C.L.5    Ennis, S.6
  • 45
    • 80855128787 scopus 로고    scopus 로고
    • Structural basis of mannanbinding lectin recognition by its associated serine protease MASP-1: Implications for complement activation
    • Gingras AR, Girija UV, Keeble AH, Panchal R, Mitchell DA, Moody PC et al (2011) Structural basis of mannanbinding lectin recognition by its associated serine protease MASP-1: implications for complement activation. Structure 19(11):1635-16433
    • (2011) Structure , vol.19 , Issue.11 , pp. 1635-16433
    • Gingras, A.R.1    Girija, U.V.2    Keeble, A.H.3    Panchal, R.4    Mitchell, D.A.5    Moody, P.C.6
  • 46
    • 78650149915 scopus 로고    scopus 로고
    • Aptamer-based multiplexed proteomic technology for biomarker discovery
    • Gold L, Ayers D, Bertino J, Bock C, Bock A, Brody EN et al (2010) Aptamer-based multiplexed proteomic technology for biomarker discovery. PLoS One 5(12):e150044
    • (2010) PLoS One , vol.5 , Issue.12
    • Gold, L.1    Ayers, D.2    Bertino, J.3    Bock, C.4    Bock, A.5    Brody, E.N.6
  • 47
    • 84865785162 scopus 로고    scopus 로고
    • Complement anaphylatoxin C3a as a novel independent prognostic marker in heart failure
    • doi:10.1007/s00392-012-0432-66
    • Gombos T, Forhecz Z, Pozsonyi Z, Szeplaki G, Kunde J, Fust G et al (2012) Complement anaphylatoxin C3a as a novel independent prognostic marker in heart failure. Clin Res Cardiol. doi:10.1007/s00392-012-0432-66
    • (2012) Clin Res Cardiol.
    • Gombos, T.1    Forhecz, Z.2    Pozsonyi, Z.3    Szeplaki, G.4    Kunde, J.5    Fust, G.6
  • 48
    • 80052633761 scopus 로고    scopus 로고
    • Cinryze (C1-inhibitor) for the treatment of hereditary angioedema
    • Gompels MM, Lock RJ (2011) Cinryze (C1-inhibitor) for the treatment of hereditary angioedema. Expert Rev Clin Immunol 7(5):569-5733
    • (2011) Expert Rev Clin Immunol , vol.7 , Issue.5 , pp. 569-5733
    • Gompels, M.M.1    Lock, R.J.2
  • 49
    • 56349105099 scopus 로고    scopus 로고
    • Puri fication of truncated and mutated chemotaxis inhibitory protein of Staphylococcus aureus - An anti-inflammatory protein
    • Gustafsson E, Forsberg C, Haraldsson K, Lindman S, Ljung L, Furebring C (2009) Puri fication of truncated and mutated chemotaxis inhibitory protein of Staphylococcus aureus - an anti-inflammatory protein. Protein Expr Purif 63(2):95-1011
    • (2009) Protein Expr Purif , vol.63 , Issue.2 , pp. 95-1011
    • Gustafsson, E.1    Forsberg, C.2    Haraldsson, K.3    Lindman, S.4    Ljung, L.5    Furebring, C.6
  • 50
    • 84861163710 scopus 로고    scopus 로고
    • Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9
    • Hadders MA, Bubeck D, Roversi P, Hakobyan S, Forneris F, Morgan BP et al (2012) Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9. Cell Rep 1:1-88
    • (2012) Cell Rep , vol.1 , pp. 1-88
    • Hadders, M.A.1    Bubeck, D.2    Roversi, P.3    Hakobyan, S.4    Forneris, F.5    Morgan, B.P.6
  • 51
    • 69749125540 scopus 로고    scopus 로고
    • Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation
    • Halili MA, Ruiz-Gomez G, Le GT, Abbenante G, Fairlie DP (2009) Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation. Biochemistry 48(35):8466-84722
    • (2009) Biochemistry , vol.48 , Issue.35 , pp. 8466-84722
    • Halili, M.A.1    Ruiz-Gomez, G.2    Le Abbenante, G.T.G.3    Fairlie, D.P.4
  • 53
    • 77649291314 scopus 로고    scopus 로고
    • Genetic control of the alternative pathway of complement in humans and age-related macular degeneration
    • Hecker LA, Edwards AO, Ryu E, Tosakulwong N, Baratz KH, Brown WL et al (2010) Genetic control of the alternative pathway of complement in humans and age-related macular degeneration. Hum Mol Genet 19(1):209-2155
    • (2010) Hum Mol Genet , vol.19 , Issue.1 , pp. 209-2155
    • Hecker, L.A.1    Edwards, A.O.2    Ryu, E.3    Tosakulwong, N.4    Baratz, K.H.5    Brown, W.L.6
  • 54
    • 34247263765 scopus 로고    scopus 로고
    • In vivo characterization and therapeutic efficacy of a C5-specific inhibitor from the soft tick Ornithodoros moubata
    • Hepburn NJ, Williams AS, Nunn MA, Chamberlain-Banoub JC, Hamer J, Morgan BP et al (2007) In vivo characterization and therapeutic efficacy of a C5-specific inhibitor from the soft tick Ornithodoros moubata . J Biol Chem 282(11):8292-82999
    • (2007) J Biol Chem , vol.282 , Issue.11 , pp. 8292-82999
    • Hepburn, N.J.1    Williams, A.S.2    Nunn, M.A.3    Chamberlain-Banoub, J.C.4    Hamer, J.5    Morgan, B.P.6
  • 56
    • 71849106514 scopus 로고    scopus 로고
    • A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury
    • Huang Y, Qiao F, Atkinson C, Holers VM, Tomlinson S (2008) A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury. J Immunol 181(11):8068-80766
    • (2008) J Immunol , vol.181 , Issue.11 , pp. 8068-80766
    • Huang, Y.1    Qiao, F.2    Atkinson, C.3    Holers, V.M.4    Tomlinson, S.5
  • 58
    • 25644452794 scopus 로고    scopus 로고
    • Structures of complement component C3 provide insights into the function and evolution of immunity
    • Janssen BJ, Huizinga EG, Raaijmakers HC, Roos A, Daha MR, Nilsson-Ekdahl K et al (2005) Structures of complement component C3 provide insights into the function and evolution of immunity. Nature 437(7058):505-5111
    • (2005) Nature , vol.437 , Issue.7058 , pp. 505-5111
    • Janssen, B.J.1    Huizinga, E.G.2    Raaijmakers, H.C.3    Roos, A.4    Daha, M.R.5    Nilsson-Ekdahl, K.6
  • 59
    • 33750859976 scopus 로고    scopus 로고
    • Structure of C3b reveals conformational changes that underlie complement activity
    • Janssen BJ, Christodoulidou A, McCarthy A, Lambris JD, Gros P (2006) Structure of C3b reveals conformational changes that underlie complement activity. Nature 444(7116):213-2166
    • (2006) Nature , vol.444 , Issue.7116 , pp. 213-2166
    • Janssen, B.J.1    Christodoulidou, A.2    McCarthy, A.3    Lambris, J.D.4    Gros, P.5
  • 60
    • 79952612300 scopus 로고    scopus 로고
    • Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement
    • Kajander T, Lehtinen MJ, Hyvarinen S, Bhattacharjee A, Leung E, Isenman DE et al (2011) Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement. Proc Natl Acad Sci USA 108(7):2897-29022
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.7 , pp. 2897-29022
    • Kajander, T.1    Lehtinen, M.J.2    Hyvarinen, S.3    Bhattacharjee, A.4    Leung, E.5    Isenman, D.E.6
  • 61
    • 0037443910 scopus 로고    scopus 로고
    • Complement fragment C4d deposition in peritubular capillaries in acute humoral rejection after ABO blood group-incompatible human kidney transplantation
    • Kato M, Morozumi K, Takeuchi O, Oikawa T, Koyama K, Usami T et al (2003) Complement fragment C4d deposition in peritubular capillaries in acute humoral rejection after ABO blood group-incompatible human kidney transplantation. Transplantation 75(5):663-6655
    • (2003) Transplantation , vol.75 , Issue.5 , pp. 663-6655
    • Kato, M.1    Morozumi, K.2    Takeuchi, O.3    Oikawa, T.4    Koyama, K.5    Usami, T.6
  • 62
    • 70450201071 scopus 로고    scopus 로고
    • Human C1-esterase inhibitor concentrate (Berinert
    • Keating GM (2009) Human C1-esterase inhibitor concentrate (Berinert). BioDrugs 23(6):399-4066
    • (2009) BioDrugs , vol.23 , Issue.6 , pp. 399-4066
    • Keating, G.M.1
  • 63
    • 81355146502 scopus 로고    scopus 로고
    • CD4+ T cells and complement independently mediate graft ischemia in the rejection of mouse orthotopic tracheal transplants
    • Khan MA, Jiang X, Dhillon G, Beilke J, Holers VM, Atkinson C et al (2011) CD4+ T cells and complement independently mediate graft ischemia in the rejection of mouse orthotopic tracheal transplants. Circ Res 109(11): 1290-13011
    • (2011) Circ Res , vol.109 , Issue.11 , pp. 1290-13011
    • Khan, M.A.1    Jiang, X.2    Dhillon, G.3    Beilke, J.4    Holers, V.M.5    Atkinson, C.6
  • 64
    • 0034930015 scopus 로고    scopus 로고
    • C1-inhibitor: An anti-inflammatory reagent with therapeutic potential
    • Kirschfink M, Mollnes TE (2001) C1-inhibitor: an anti-inflammatory reagent with therapeutic potential. Expert Opin Pharmacother 2(7):1073-10833
    • (2001) Expert Opin Pharmacother , vol.2 , Issue.7 , pp. 1073-10833
    • Kirschfink, M.1    Mollnes, T.E.2
  • 66
    • 77958128617 scopus 로고    scopus 로고
    • Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: Significant contribution of MASP-1 to lectin pathway activation
    • Kocsis A, Kekesi KA, Szasz R, Vegh BM, Balczer J, Dobo J et al (2010) Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation. J Immunol 185(7):4169-41788
    • (2010) J Immunol , vol.185 , Issue.7 , pp. 4169-41788
    • Kocsis, A.1    Kekesi, K.A.2    Szasz, R.3    Vegh, B.M.4    Balczer, J.5    Dobo, J.6
  • 67
    • 33845514506 scopus 로고    scopus 로고
    • Drug evaluation: The C5a receptor antagonist PMX-53
    • Kohl J (2006) Drug evaluation: the C5a receptor antagonist PMX-53. Curr Opin Mol Ther 8(6):529-5388
    • (2006) Curr Opin Mol Ther , vol.8 , Issue.6 , pp. 529-5388
    • Kohl, J.1
  • 68
    • 79960705737 scopus 로고    scopus 로고
    • Tumor-specific peptide-based vaccines containing the conformationally biased, response-selective C5a agonists EP54 and EP67 protect against aggressive large B cell lymphoma in a syngeneic murine model
    • Kollessery G, Nordgren TM, Mittal AK, Joshi SS, Sanderson SD (2011) Tumor-specific peptide-based vaccines containing the conformationally biased, response-selective C5a agonists EP54 and EP67 protect against aggressive large B cell lymphoma in a syngeneic murine model. Vaccine 29(35):5904-59100
    • (2011) Vaccine , vol.29 , Issue.35 , pp. 5904-59100
    • Kollessery, G.1    Nordgren, T.M.2    Mittal, A.K.3    Joshi, S.S.4    Sanderson, S.D.5
  • 69
    • 77955854473 scopus 로고    scopus 로고
    • Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis
    • Kourtzelis I, Markiewski MM, Doumas M, Rafail S, Kambas K, Mitroulis I et al (2010) Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis. Blood 116(4):631-6399
    • (2010) Blood , vol.116 , Issue.4 , pp. 631-6399
    • Kourtzelis, I.1    Markiewski, M.M.2    Doumas, M.3    Rafail, S.4    Kambas, K.5    Mitroulis, I.6
  • 70
    • 80054736634 scopus 로고    scopus 로고
    • From SOMAmer-based biomarker discovery to diagnostic and clinical applications: A SOMAmer-based, streamlined multiplex proteomic assay
    • Kraemer S, Vaught JD, Bock C, Gold L, Katilius E, Keeney TR et al (2011) From SOMAmer-based biomarker discovery to diagnostic and clinical applications: a SOMAmer-based, streamlined multiplex proteomic assay. PLoS One 6(10):e263322
    • (2011) PLoS One , vol.6 , Issue.10
    • Kraemer, S.1    Vaught, J.D.2    Bock, C.3    Gold, L.4    Katilius, E.5    Keeney, T.R.6
  • 71
    • 79951690119 scopus 로고    scopus 로고
    • Modulation of anxiety behavior by intranasally administered vaccinia virus complement control protein and curcumin in a mouse model of Alzheimer's disease
    • Kulkarni AP, Govender DA, Kotwal GJ, Kellaway LA (2011) Modulation of anxiety behavior by intranasally administered vaccinia virus complement control protein and curcumin in a mouse model of Alzheimer's disease. Curr Alzheimer Res 8(1):95-1133
    • (2011) Curr Alzheimer Res , vol.8 , Issue.1 , pp. 95-1133
    • Kulkarni, A.P.1    Govender, D.A.2    Kotwal, G.J.3    Kellaway, L.A.4
  • 72
    • 77951207010 scopus 로고    scopus 로고
    • Complement inhibition by gram-positive pathogens: Molecular mechanisms and therapeutic implications
    • Laarman A, Milder F, van Strijp J, Rooijakkers S (2010) Complement inhibition by gram-positive pathogens: molecular mechanisms and therapeutic implications. J Mol Med (Berlin) 88(2):115-1200
    • (2010) J Mol Med (Berlin) , vol.88 , Issue.2 , pp. 115-1200
    • Laarman, A.1    Milder, F.2    Van Strijp, J.3    Rooijakkers, S.4
  • 73
    • 65349094547 scopus 로고    scopus 로고
    • Taking complement to the clinic - Has the time fi nally come?
    • Lachmann PJ, Smith RA (2009) Taking complement to the clinic - has the time fi nally come? Scand J Immunol 69(6):471-4788
    • (2009) Scand J Immunol , vol.69 , Issue.6 , pp. 471-4788
    • Lachmann, P.J.1    Smith, R.A.2
  • 74
    • 78549264026 scopus 로고    scopus 로고
    • Genome-wide association study identi fies variants at CLU and CR1 associated with Alzheimer's disease
    • Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M et al (2009) Genome-wide association study identi fies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 41(10):1094-10999
    • (2009) Nat Genet , vol.41 , Issue.10 , pp. 1094-10999
    • Lambert, J.C.1    Heath, S.2    Even, G.3    Campion, D.4    Sleegers, K.5    Hiltunen, M.6
  • 77
    • 84856400432 scopus 로고    scopus 로고
    • E. coli crisis opens door for Alexion drug trial
    • Laursen L (2011) E. coli crisis opens door for Alexion drug trial. Nat Biotechnol 29(8):6711
    • (2011) Nat Biotechnol , vol.29 , Issue.8 , pp. 6711
    • Laursen, L.1
  • 78
    • 77649257894 scopus 로고    scopus 로고
    • Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus
    • Laursen NS, Gordon N, Hermans S, Lorenz N, Jackson N, Wines B et al (2010) Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus . Proc Natl Acad Sci USA 107(8):3681-36866
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.8 , pp. 3681-36866
    • Laursen, N.S.1    Gordon, N.2    Hermans, S.3    Lorenz, N.4    Jackson, N.5    Wines, B.6
  • 79
    • 79551581253 scopus 로고    scopus 로고
    • Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex
    • Laursen NS, Andersen KR, Braren I, Spillner E, Sottrup-Jensen L, Andersen GR (2011) Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex. EMBO J 30(3):606-6166
    • (2011) EMBO J , vol.30 , Issue.3 , pp. 606-6166
    • Laursen, N.S.1    Andersen, K.R.2    Braren, I.3    Spillner, E.4    Sottrup-Jensen, L.5    Andersen, G.R.6
  • 80
    • 34748814406 scopus 로고    scopus 로고
    • Beneficial effects of complement inhibition with soluble complement receptor 1 (TP10) during cardiac surgery: Is there a gender difference?
    • Lazar HL, Keilani T, Fitzgerald CA, Shapira OM, Hunter CT, Shemin RJ et al (2007) Beneficial effects of complement inhibition with soluble complement receptor 1 (TP10) during cardiac surgery: is there a gender difference? Circulation 116(11 Suppl):I83-I888
    • (2007) Circulation , vol.116 , Issue.11 SUPPL.
    • Lazar, H.L.1    Keilani, T.2    Fitzgerald, C.A.3    Shapira, O.M.4    Hunter, C.T.5    Shemin, R.J.6
  • 81
    • 44949261153 scopus 로고    scopus 로고
    • Pharmacological targeting of C5a receptors during organ preservation improves kidney graft survival
    • Lewis AG, Kohl G, Ma Q, Devarajan P, Kohl J (2008) Pharmacological targeting of C5a receptors during organ preservation improves kidney graft survival. Clin Exp Immunol 153(1):117-1266
    • (2008) Clin Exp Immunol , vol.153 , Issue.1 , pp. 117-1266
    • Lewis, A.G.1    Kohl, G.2    Ma, Q.3    Devarajan, P.4    Kohl, J.5
  • 82
    • 33750935095 scopus 로고    scopus 로고
    • The use of TP10, soluble complement receptor 1, in cardiopulmonary bypass
    • Li JS, Jaggers J, Anderson PA (2006) The use of TP10, soluble complement receptor 1, in cardiopulmonary bypass. Expert Rev Cardiovasc Ther 4(5):649-6544
    • (2006) Expert Rev Cardiovasc Ther , vol.4 , Issue.5 , pp. 649-6544
    • Li, J.S.1    Jaggers, J.2    Anderson, P.A.3
  • 83
    • 20144373025 scopus 로고    scopus 로고
    • Successful plasma therapy for atypical hemolytic uremic syndrome caused by factor H Deficiency owing to a novel mutation in the complement cofactor protein domain 15
    • Licht C, Weyersberg A, Heinen S, Stapenhorst L, Devenge J, Beck B et al (2005) Successful plasma therapy for atypical hemolytic uremic syndrome caused by factor H Deficiency owing to a novel mutation in the complement cofactor protein domain 15. Am J Kidney Dis 45(2):415-4211
    • (2005) Am J Kidney Dis , vol.45 , Issue.2 , pp. 415-4211
    • Licht, C.1    Weyersberg, A.2    Heinen, S.3    Stapenhorst, L.4    Devenge, J.5    Beck, B.6
  • 84
    • 77950636875 scopus 로고    scopus 로고
    • Paroxysmal nocturnal hemoglobinuria and eculizumab
    • Luzzatto L, Risitano AM, Notaro R (2010) Paroxysmal nocturnal hemoglobinuria and eculizumab. Haematologica 95(4):523-5266
    • (2010) Haematologica , vol.95 , Issue.4 , pp. 523-5266
    • Luzzatto, L.1    Risitano, A.M.2    Notaro, R.3
  • 86
    • 78650768741 scopus 로고    scopus 로고
    • Early elevations of the complement activation fragment C3a and adverse pregnancy outcomes
    • Lynch AM, Gibbs RS, Murphy JR, Giclas PC, Salmon JE, Holers VM (2011) Early elevations of the complement activation fragment C3a and adverse pregnancy outcomes. Obstet Gynecol 117(1):75-833
    • (2011) Obstet Gynecol , vol.117 , Issue.1 , pp. 75-833
    • Lynch, A.M.1    Gibbs, R.S.2    Murphy, J.R.3    Giclas, P.C.4    Salmon, J.E.5    Holers, V.M.6
  • 87
    • 66549124166 scopus 로고    scopus 로고
    • Is complement good or bad for cancer patients? A new perspective on an old dilemma
    • Markiewski MM, Lambris JD (2009) Is complement good or bad for cancer patients? A new perspective on an old dilemma. Trends Immunol 30(6):286-2922
    • (2009) Trends Immunol , vol.30 , Issue.6 , pp. 286-2922
    • Markiewski, M.M.1    Lambris, J.D.2
  • 90
    • 35348821843 scopus 로고    scopus 로고
    • Function, structure and therapeutic potential of complement C5a receptors
    • Monk PN, Scola AM, Madala P, Fairlie DP (2007) Function, structure and therapeutic potential of complement C5a receptors. Br J Pharmacol 152(4):429-4488
    • (2007) Br J Pharmacol , vol.152 , Issue.4 , pp. 429-4488
    • Monk, P.N.1    Scola, A.M.2    Madala, P.3    Fairlie, D.P.4
  • 92
    • 84455181468 scopus 로고    scopus 로고
    • C3 and C4 complement system components as biomarkers in the intermittent atopic asthma diagnosis
    • Mosca T, Menezes MC, Dionigi PC, Stirbulov R, Forte WC (2011) C3 and C4 complement system components as biomarkers in the intermittent atopic asthma diagnosis. J Pediatr (Rio de Janeiro) 87(6):512-5166
    • (2011) J Pediatr (Rio de Janeiro) , vol.87 , Issue.6 , pp. 512-5166
    • Mosca, T.1    Menezes, M.C.2    Dionigi, P.C.3    Stirbulov, R.4    Forte, W.C.5
  • 93
    • 84857712365 scopus 로고    scopus 로고
    • Protein-protein interaction inhibitors get into the groove
    • Mullard A (2012) Protein-protein interaction inhibitors get into the groove. Nat Rev Drug Discov 11(3):173-1755
    • (2012) Nat Rev Drug Discov , vol.11 , Issue.3 , pp. 173-1755
    • Mullard, A.1
  • 94
    • 0032557324 scopus 로고    scopus 로고
    • X-ray crystal structure of C3d: A C3 fragment and ligand for complement receptor 2
    • Nagar B, Jones RG, Diefenbach RJ, Isenman DE, Rini JM (1998) X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2. Science 280(5367):1277-12811
    • (1998) Science , vol.280 , Issue.5367 , pp. 1277-12811
    • Nagar, B.1    Jones, R.G.2    Diefenbach, R.J.3    Isenman, D.E.4    Rini, J.M.5
  • 95
    • 0027948496 scopus 로고
    • Reconstitution of the alternative pathway of complement by plasma infusions given to a patient with an SLE-like syndrome associated with a hereditary C3 dysfunction
    • Nilsson B, Nilsson UR, Karlsson-Parra A, Sjolin-Forsberg G, Hallgren R (1994) Reconstitution of the alternative pathway of complement by plasma infusions given to a patient with an SLE-like syndrome associated with a hereditary C3 dysfunction. Ann Rheum Dis 53(10):691-6944
    • (1994) Ann Rheum Dis , vol.53 , Issue.10 , pp. 691-6944
    • Nilsson, B.1    Nilsson, U.R.2    Karlsson-Parra, A.3    Sjolin-Forsberg, G.4    Hallgren, R.5
  • 96
    • 73149108627 scopus 로고    scopus 로고
    • Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?
    • Nilsson B, Korsgren O, Lambris JD, Ekdahl KN (2010) Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition? Trends Immunol 31(1):32-388
    • (2010) Trends Immunol , vol.31 , Issue.1 , pp. 32-388
    • Nilsson, B.1    Korsgren, O.2    Lambris, J.D.3    Ekdahl, K.N.4
  • 97
    • 13544272921 scopus 로고    scopus 로고
    • Complement inhibitor of C5 activation from the soft tick Ornithodoros moubata
    • Nunn MA, Sharma A, Paesen GC, Adamson S, Lissina O, Willis AC et al (2005) Complement inhibitor of C5 activation from the soft tick Ornithodoros moubata . J Immunol 174(4):2084-20911
    • (2005) J Immunol , vol.174 , Issue.4 , pp. 2084-20911
    • Nunn, M.A.1    Sharma, A.2    Paesen, G.C.3    Adamson, S.4    Lissina, O.5    Willis, A.C.6
  • 99
    • 84857532767 scopus 로고    scopus 로고
    • Interactions between coagulation and complement - Their role in in flammation
    • Oikonomopoulou K, Ricklin D, Ward PA, Lambris JD (2012) Interactions between coagulation and complement - their role in in flammation. Semin Immunopathol 34(1):151-1655
    • (2012) Semin Immunopathol , vol.34 , Issue.1 , pp. 151-1655
    • Oikonomopoulou, K.1    Ricklin, D.2    Ward, P.A.3    Lambris, J.D.4
  • 100
    • 0347052898 scopus 로고    scopus 로고
    • C5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: Position 69 is the locus that determines agonism or antagonism
    • Otto M, Hawlisch H, Monk PN, Muller M, Klos A, Karp CL et al (2004) C5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: position 69 is the locus that determines agonism or antagonism. J Biol Chem 279(1):142-1511
    • (2004) J Biol Chem , vol.279 , Issue.1 , pp. 142-1511
    • Otto, M.1    Hawlisch, H.2    Monk, P.N.3    Muller, M.4    Klos, A.5    Karp, C.L.6
  • 101
    • 33947608775 scopus 로고    scopus 로고
    • Serum complement C3/C4 ratio, a novel marker for recurrent cardiovascular events
    • Palikhe A, Sinisalo J, Seppanen M, Haario H, Meri S, Valtonen V et al (2007) Serum complement C3/C4 ratio, a novel marker for recurrent cardiovascular events. Am J Cardiol 99(7):890-8955
    • (2007) Am J Cardiol , vol.99 , Issue.7 , pp. 890-8955
    • Palikhe, A.1    Sinisalo, J.2    Seppanen, M.3    Haario, H.4    Meri, S.5    Valtonen, V.6
  • 102
    • 84859845593 scopus 로고    scopus 로고
    • Paroxysmal nocturnal hemoglobinuria
    • Parker CJ (2012) Paroxysmal nocturnal hemoglobinuria. Curr Opin Hematol 19(3):141-1488
    • (2012) Curr Opin Hematol , vol.19 , Issue.3 , pp. 141-1488
    • Parker, C.J.1
  • 103
    • 33645473397 scopus 로고    scopus 로고
    • Therapeutic strategy with a membrane-localizing complement regulator to increase the number of usable donor organs after prolonged cold storage
    • Patel H, Smith RA, Sacks SH, Zhou W (2006) Therapeutic strategy with a membrane-localizing complement regulator to increase the number of usable donor organs after prolonged cold storage. J Am Soc Nephrol 17(4):1102-11111
    • (2006) J Am Soc Nephrol , vol.17 , Issue.4 , pp. 1102-11111
    • Patel, H.1    Smith, R.A.2    Sacks, S.H.3    Zhou, W.4
  • 104
    • 0036863301 scopus 로고    scopus 로고
    • Solution structures of complement components by X-ray and neutron scattering and analytical ultracentrifugation
    • Perkins SJ, Gilbert HE, Aslam M, Hannan J, Holers VM, Goodship TH (2002) Solution structures of complement components by X-ray and neutron scattering and analytical ultracentrifugation. Biochem Soc Trans 30(Pt 6): 996-10011
    • (2002) Biochem Soc Trans , vol.30 , Issue.PART 6 , pp. 996-10011
    • Perkins, S.J.1    Gilbert, H.E.2    Aslam, M.3    Hannan, J.4    Holers, V.M.5    Goodship, T.H.6
  • 105
    • 0036863301 scopus 로고    scopus 로고
    • Solution structures of complement components by X-ray and neutron scattering and analytical ultracentrifugation
    • Perkins SJ, Gilbert HE, Aslam M, Hannan J, Holers VM, Goodship TH (2002) Solution structures of complement components by X-ray and neutron scattering and analytical ultracentrifugation. Biochem Soc Trans 30(Pt 6):996-10011
    • (2002) Biochem Soc Trans , vol.30 , Issue.PART 6 , pp. 996-10011
    • Perkins, S.J.1    Gilbert, H.E.2    Aslam, M.3    Hannan, J.4    Holers, V.M.5    Goodship, T.H.6
  • 106
    • 84862830163 scopus 로고    scopus 로고
    • Alzheimer's disease and agerelated macular degeneration have different genetic models for complement gene variation
    • Proitsi P, Lupton MK, Dudbridge F, Tsolaki M, Hamilton G, Daniilidou M et al (2012) Alzheimer's disease and agerelated macular degeneration have different genetic models for complement gene variation. Neurobiol Aging 33(8):1843.e9-1843.e177
    • (2012) Neurobiol Aging , vol.33 , Issue.8
    • Proitsi, P.1    Lupton, M.K.2    Dudbridge, F.3    Tsolaki, M.4    Hamilton, G.5    Daniilidou, M.6
  • 108
    • 70450224874 scopus 로고    scopus 로고
    • Recent developments in low molecular weight complement inhibitors
    • Qu H, Ricklin D, Lambris JD (2009) Recent developments in low molecular weight complement inhibitors. Mol Immunol 47(2-3):185-1955
    • (2009) Mol Immunol , vol.47 , Issue.2-3 , pp. 185-1955
    • Qu, H.1    Ricklin, D.2    Lambris, J.D.3
  • 109
    • 78650620316 scopus 로고    scopus 로고
    • Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency
    • Qu H, Magotti P, Ricklin D, Wu EL, Kourtzelis I, Wu YQ et al (2011) Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency. Mol Immunol 48(4):481-4899
    • (2011) Mol Immunol , vol.48 , Issue.4 , pp. 481-4899
    • Qu, H.1    Magotti, P.2    Ricklin, D.3    Wu, E.L.4    Kourtzelis, I.5    Wu, Y.Q.6
  • 110
    • 7644229013 scopus 로고    scopus 로고
    • Hypocomplementemia in systemic lupus erythematosus and primary antiphospholipid syndrome: Prevalence and clinical significance in 667 patients
    • Ramos-Casals M, Campoamor MT, Chamorro A, Salvador G, Segura S, Botero JC et al (2004) Hypocomplementemia in systemic lupus erythematosus and primary antiphospholipid syndrome: prevalence and clinical significance in 667 patients. Lupus 13(10):777-7833
    • (2004) Lupus , vol.13 , Issue.10 , pp. 777-7833
    • Ramos-Casals, M.1    Campoamor, M.T.2    Chamorro, A.3    Salvador, G.4    Segura, S.5    Botero, J.C.6
  • 111
    • 84857032563 scopus 로고    scopus 로고
    • C5aR-antagonist significantly reduces the deleterious effect of a blunt chest trauma on fracture healing
    • Recknagel S, Bindl R, Kurz J, Wehner T, Schoengraf P, Ehrnthaller C et al (2012) C5aR-antagonist significantly reduces the deleterious effect of a blunt chest trauma on fracture healing. J Orthop Res 30(4):581-5866
    • (2012) J Orthop Res , vol.30 , Issue.4 , pp. 581-5866
    • Recknagel, S.1    Bindl, R.2    Kurz, J.3    Wehner, T.4    Schoengraf, P.5    Ehrnthaller, C.6
  • 112
    • 33644830187 scopus 로고    scopus 로고
    • Clinical aspects and molecular basis of primary de ficiencies of complement component C3 and its regulatory proteins factor i and factor H
    • Reis SE, Falcao DA, Isaac L (2006) Clinical aspects and molecular basis of primary de ficiencies of complement component C3 and its regulatory proteins factor I and factor H. Scand J Immunol 63(3):155-1688
    • (2006) Scand J Immunol , vol.63 , Issue.3 , pp. 155-1688
    • Reis, S.E.1    Falcao, D.A.2    Isaac, L.3
  • 113
    • 73349112242 scopus 로고    scopus 로고
    • Plasma complement components and activation fragments: Associations with age-related macular degeneration genotypes and phenotypes
    • Reynolds R, Hartnett ME, Atkinson JP, Giclas PC, Rosner B, Seddon JM (2009) Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes. Invest Ophthalmol Vis Sci 50(12):5818-58277
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.12 , pp. 5818-58277
    • Reynolds, R.1    Hartnett, M.E.2    Atkinson, J.P.3    Giclas, P.C.4    Rosner, B.5    Seddon, J.M.6
  • 114
    • 36048937343 scopus 로고    scopus 로고
    • Complement-targeted therapeutics
    • Ricklin D, Lambris JD (2007a) Complement-targeted therapeutics. Nat Biotechnol 25(11):1265-12755
    • (2007) Nat Biotechnol , vol.25 , Issue.11 , pp. 1265-12755
    • Ricklin, D.1    Lambris, J.D.2
  • 115
    • 84934441970 scopus 로고    scopus 로고
    • Exploring the complement interaction network using surface plasmon resonance
    • Ricklin D, Lambris JD (2007b) Exploring the complement interaction network using surface plasmon resonance. Adv Exp Med Biol 598:260-2788
    • (2007) Adv Exp Med Biol , vol.598 , pp. 260-2788
    • Ricklin, D.1    Lambris, J.D.2
  • 116
    • 52649116114 scopus 로고    scopus 로고
    • Compstatin: A complement inhibitor on its way to clinical application
    • Ricklin D, Lambris JD (2008) Compstatin: a complement inhibitor on its way to clinical application. Adv Exp Med Biol 632:273-2922
    • (2008) Adv Exp Med Biol , vol.632 , pp. 273-2922
    • Ricklin, D.1    Lambris, J.D.2
  • 117
    • 77955883153 scopus 로고    scopus 로고
    • Complement: A key system for immune surveillance and homeostasis
    • Ricklin D, Hajishengallis G, Yang K, Lambris JD (2010) Complement: a key system for immune surveillance and homeostasis. Nat Immunol 11(9):785-7977
    • (2010) Nat Immunol , vol.11 , Issue.9 , pp. 785-7977
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 118
    • 79959467643 scopus 로고    scopus 로고
    • Achievements and limitations of complement inhibition by eculizumab in paroxysmal nocturnal hemoglobinuria: The role of complement component 3
    • Risitano AM, Perna F, Selleri C (2011) Achievements and limitations of complement inhibition by eculizumab in paroxysmal nocturnal hemoglobinuria: the role of complement component 3. Mini Rev Med Chem 11(6):528-5355
    • (2011) Mini Rev Med Chem , vol.11 , Issue.6 , pp. 528-5355
    • Risitano, A.M.1    Perna, F.2    Selleri, C.3
  • 119
    • 78649450284 scopus 로고    scopus 로고
    • Lessons from functional and structural analyses of disease-associated genetic variants in the complement alternative pathway
    • Rodriguez de Cordoba S, Harris CL, Morgan BP, Llorca O (2011) Lessons from functional and structural analyses of disease-associated genetic variants in the complement alternative pathway. Biochim Biophys Acta 1812(1):12-222
    • (2011) Biochim Biophys Acta , vol.1812 , Issue.1 , pp. 12-222
    • Rodriguez De Cordoba, S.1    Harris, C.L.2    Morgan, B.P.3    Llorca, O.4
  • 120
    • 79952119070 scopus 로고    scopus 로고
    • A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration
    • Rohrer B, Long Q, Coughlin B, Renner B, Huang Y, Kunchithapautham K et al (2010) A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration. Adv Exp Med Biol 703:137-1499
    • (2010) Adv Exp Med Biol , vol.703 , pp. 137-1499
    • Rohrer, B.1    Long, Q.2    Coughlin, B.3    Renner, B.4    Huang, Y.5    Kunchithapautham, K.6
  • 121
    • 84864605570 scopus 로고    scopus 로고
    • Systemic human CR2-targeted complement alternative pathway inhibitor ameliorates mouse laser-induced choroidal neovascularization
    • doi:10.1089/jop.2011.02122
    • Rohrer B, Coughlin B, Bandyopadhyay M, Holers VM (2012) Systemic human CR2-targeted complement alternative pathway inhibitor ameliorates mouse laser-induced choroidal neovascularization. J Ocul Pharmacol Ther. doi:10.1089/jop.2011.02122
    • (2012) J Ocul Pharmacol Ther.
    • Rohrer, B.1    Coughlin, B.2    Bandyopadhyay, M.3    Holers, V.M.4
  • 122
    • 67649221223 scopus 로고    scopus 로고
    • Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor
    • Rooijakkers SH, Wu J, Ruyken M, van Domselaar R, Planken KL, Tzekou A et al (2009) Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor. Nat Immunol 10(7):721-7277
    • (2009) Nat Immunol , vol.10 , Issue.7 , pp. 721-7277
    • Rooijakkers, S.H.1    Wu, J.2    Ruyken, M.3    Van Domselaar, R.4    Planken, K.L.5    Tzekou, A.6
  • 123
    • 79960076285 scopus 로고    scopus 로고
    • Chronic treatment of paroxysmal nocturnal hemoglobinuria patients with eculizumab: Safety, efficacy, and unexpected laboratory phenomena
    • Roth A, Hock C, Konik A, Christoph S, Duhrsen U (2011) Chronic treatment of paroxysmal nocturnal hemoglobinuria patients with eculizumab: safety, efficacy, and unexpected laboratory phenomena. Int J Hematol 93(6):704-7144
    • (2011) Int J Hematol , vol.93 , Issue.6 , pp. 704-7144
    • Roth, A.1    Hock, C.2    Konik, A.3    Christoph, S.4    Duhrsen, U.5
  • 124
    • 34248165965 scopus 로고    scopus 로고
    • The structure of OMCI, a novel lipocalin inhibitor of the complement system
    • Roversi P, Lissina O, Johnson S, Ahmat N, Paesen GC, Ploss K et al (2007) The structure of OMCI, a novel lipocalin inhibitor of the complement system. J Mol Biol 369(3):784-7933
    • (2007) J Mol Biol , vol.369 , Issue.3 , pp. 784-7933
    • Roversi, P.1    Lissina, O.2    Johnson, S.3    Ahmat, N.4    Paesen, G.C.5    Ploss, K.6
  • 125
    • 70349640052 scopus 로고    scopus 로고
    • Structure-activity relationships for substrate-based inhibitors of human complement factor B
    • Ruiz-Gomez G, Lim J, Halili MA, Le GT, Madala PK, Abbenante G et al (2009) Structure-activity relationships for substrate-based inhibitors of human complement factor B. J Med Chem 52(19):6042-60522
    • (2009) J Med Chem , vol.52 , Issue.19 , pp. 6042-60522
    • Ruiz-Gomez, G.1    Lim, J.2    Halili, M.A.3    Le Madala, G.T.P.K.4    Abbenante, G.5
  • 126
    • 84861538912 scopus 로고    scopus 로고
    • The role of complement in the early response to transplantation
    • Sacks SH, Zhou W (2012) The role of complement in the early response to transplantation. Nat Rev Immunol 12(6):431-4422
    • (2012) Nat Rev Immunol , vol.12 , Issue.6 , pp. 431-4422
    • Sacks, S.H.1    Zhou, W.2
  • 127
    • 0030013492 scopus 로고    scopus 로고
    • Inhibition of human complement by a C3-binding peptide isolated from a phagedisplayed
    • random peptide library
    • Sahu A, Kay BK, Lambris JD (1996) Inhibition of human complement by a C3-binding peptide isolated from a phagedisplayed random peptide library. J Immunol 157(2):884-8911
    • (1996) J Immunol , vol.157 , Issue.2 , pp. 884-8911
    • Sahu, A.1    Kay, B.K.2    Lambris, J.D.3
  • 128
    • 84934438050 scopus 로고    scopus 로고
    • Mirococept could double life of transplant organs
    • Sample I (2010) Mirococept could double life of transplant organs. The Guardian 2010. http://www.guardian.co.uk/science/2010/sep/15/mirococept- transplant-organs
    • (2010) The Guardian 2010
    • Sample, I.1
  • 129
    • 80054755744 scopus 로고    scopus 로고
    • Antibody microarrays as tools for biomarker discovery
    • Sanchez-Carbayo M (2011) Antibody microarrays as tools for biomarker discovery. Methods Mol Biol 785:159-1822
    • (2011) Methods Mol Biol , vol.785 , pp. 159-1822
    • Sanchez-Carbayo, M.1
  • 130
    • 0035080989 scopus 로고    scopus 로고
    • TP20 is superior to TP10 in reducing ischemia/reperfusion injury in rat lung grafts
    • Schmid RA, Hillinger S, Hamacher J, Stammberger U (2001) TP20 is superior to TP10 in reducing ischemia/reperfusion injury in rat lung grafts. Transplant Proc 33(1-2):948-9499
    • (2001) Transplant Proc , vol.33 , Issue.1-2 , pp. 948-9499
    • Schmid, R.A.1    Hillinger, S.2    Hamacher, J.3    Stammberger, U.4
  • 133
    • 84934442924 scopus 로고    scopus 로고
    • Hydrogen/deuterium exchange mass spectrometry: Potential for investigating innate immunity proteins
    • Schuster MC, Chen H, Lambris JD (2007) Hydrogen/deuterium exchange mass spectrometry: potential for investigating innate immunity proteins. Adv Exp Med Biol 598:407-4177
    • (2007) Adv Exp Med Biol , vol.598 , pp. 407-4177
    • Schuster, M.C.1    Chen, H.2    Lambris, J.D.3
  • 134
    • 43449131563 scopus 로고    scopus 로고
    • Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry
    • Schuster MC, Ricklin D, Papp K, Molnar KS, Coales SJ, Hamuro Y et al (2008) Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry. Mol Immunol 45(11):3142-31511
    • (2008) Mol Immunol , vol.45 , Issue.11 , pp. 3142-31511
    • Schuster, M.C.1    Ricklin, D.2    Papp, K.3    Molnar, K.S.4    Coales, S.J.5    Hamuro, Y.6
  • 136
    • 78549235728 scopus 로고    scopus 로고
    • Delineation of the complement receptor type 2-C3d complex by site-directed mutagenesis and molecular docking
    • Shaw CD, Storek MJ, Young KA, Kovacs JM, Thurman JM, Holers VM et al (2010) Delineation of the complement receptor type 2-C3d complex by site-directed mutagenesis and molecular docking. J Mol Biol 404(4):697-7100
    • (2010) J Mol Biol , vol.404 , Issue.4 , pp. 697-7100
    • Shaw, C.D.1    Storek, M.J.2    Young, K.A.3    Kovacs, J.M.4    Thurman, J.M.5    Holers, V.M.6
  • 137
    • 77955901581 scopus 로고    scopus 로고
    • Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis
    • Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Sfyroera G, Magotti P et al (2010) Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis. Blood 116(6):1002-10100
    • (2010) Blood , vol.116 , Issue.6 , pp. 1002-10100
    • Silasi-Mansat, R.1    Zhu, H.2    Popescu, N.I.3    Peer, G.4    Sfyroera, G.5    Magotti, P.6
  • 138
    • 78249275859 scopus 로고    scopus 로고
    • MASP1 mutations in patients with facial, umbilical, coccygeal, and auditory fi ndings of Carnevale, Malpuech, OSA, and Michels syndromes
    • Sirmaci A, Walsh T, Akay H, Spiliopoulos M, Sakalar YB, Hasanefendioglu-Bayrak A et al (2010) MASP1 mutations in patients with facial, umbilical, coccygeal, and auditory fi ndings of Carnevale, Malpuech, OSA, and Michels syndromes. Am J Hum Genet 87(5):679-6866
    • (2010) Am J Hum Genet , vol.87 , Issue.5 , pp. 679-6866
    • Sirmaci, A.1    Walsh, T.2    Akay, H.3    Spiliopoulos, M.4    Sakalar, Y.B.5    Hasanefendioglu-Bayrak, A.6
  • 139
    • 0031455761 scopus 로고    scopus 로고
    • Hypocomplementaemia caused by C3 nephritic factors (C3 NeF): Clinical fi ndings and the coincidence of C3 NeF type II with anti-C1q autoantibodies
    • Skattum L, Martensson U, Sjoholm AG (1997) Hypocomplementaemia caused by C3 nephritic factors (C3 NeF): clinical fi ndings and the coincidence of C3 NeF type II with anti-C1q autoantibodies. J Intern Med 242(6):455-4644
    • (1997) J Intern Med , vol.242 , Issue.6 , pp. 455-4644
    • Skattum, L.1    Martensson, U.2    Sjoholm, A.G.3
  • 140
  • 141
    • 0036864134 scopus 로고    scopus 로고
    • Targeting anticomplement agents
    • Smith RA (2002) Targeting anticomplement agents. Biochem Soc Trans 30(Pt 6):1037-10411
    • (2002) Biochem Soc Trans , vol.30 , Issue.PART 6 , pp. 1037-10411
    • Smith, R.A.1
  • 142
    • 0034866117 scopus 로고    scopus 로고
    • Membrane-targeted complement inhibitors
    • Smith GP, Smith RA (2001) Membrane-targeted complement inhibitors. Mol Immunol 38(2-3):249-2555
    • (2001) Mol Immunol , vol.38 , Issue.2-3 , pp. 249-2555
    • Smith, G.P.1    Smith, R.A.2
  • 143
    • 84862676448 scopus 로고    scopus 로고
    • Activation of polymorphonuclear leukocytes by candidate biomaterials for an implantable glucose sensor
    • Sokolov A, Hellerud BC, Lambris JD, Johannessen EA, Mollnes TE (2011) Activation of polymorphonuclear leukocytes by candidate biomaterials for an implantable glucose sensor. J Diabetes Sci Technol 5(6):1490-14988
    • (2011) J Diabetes Sci Technol , vol.5 , Issue.6 , pp. 1490-14988
    • Sokolov, A.1    Hellerud, B.C.2    Lambris, J.D.3    Johannessen, E.A.4    Mollnes, T.E.5
  • 144
    • 30544432914 scopus 로고    scopus 로고
    • APT070 (Mirococept), a membrane-localised complement inhibitor, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury
    • Souza DG, Esser D, Bradford R, Vieira AT, Teixeira MM (2005) APT070 (Mirococept), a membrane-localised complement inhibitor, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury. Br J Pharmacol 145(8):1027-10344
    • (2005) Br J Pharmacol , vol.145 , Issue.8 , pp. 1027-10344
    • Souza, D.G.1    Esser, D.2    Bradford, R.3    Vieira, A.T.4    Teixeira, M.M.5
  • 145
    • 0346023953 scopus 로고    scopus 로고
    • ScFv-mediated in vivo targeting of DAF to erythrocytes inhibits lysis by complement
    • Spitzer D, Unsinger J, Bessler M, Atkinson JP (2004) ScFv-mediated in vivo targeting of DAF to erythrocytes inhibits lysis by complement. Mol Immunol 40(13):911-9199
    • (2004) Mol Immunol , vol.40 , Issue.13 , pp. 911-9199
    • Spitzer, D.1    Unsinger, J.2    Bessler, M.3    Atkinson, J.P.4
  • 146
    • 28244463961 scopus 로고    scopus 로고
    • In vivo correction of complement regulatory protein Deficiency with an inhibitor targeting the red blood cell membrane
    • Spitzer D, Unsinger J, Mao D, Wu X, Molina H, Atkinson JP (2005) In vivo correction of complement regulatory protein Deficiency with an inhibitor targeting the red blood cell membrane. J Immunol 175(11):7763-77700
    • (2005) J Immunol , vol.175 , Issue.11 , pp. 7763-77700
    • Spitzer, D.1    Unsinger, J.2    Mao, D.3    Wu, X.4    Molina, H.5    Atkinson, J.P.6
  • 147
  • 148
    • 77955246702 scopus 로고    scopus 로고
    • Anti-inflammatory effects of C1-Inhibitor in porcine and human whole blood are independent of its protease inhibition activity
    • Thorgersen EB, Ludviksen JK, Lambris JD, Sfyroera G, Nielsen EW, Mollnes TE (2010) Anti-inflammatory effects of C1-Inhibitor in porcine and human whole blood are independent of its protease inhibition activity. Innate Immun 16(4):254-2644
    • (2010) Innate Immun , vol.16 , Issue.4 , pp. 254-2644
    • Thorgersen, E.B.1    Ludviksen, J.K.2    Lambris, J.D.3    Sfyroera, G.4    Nielsen, E.W.5    Mollnes, T.E.6
  • 149
    • 77954235492 scopus 로고    scopus 로고
    • Recombinant human C1-inhibitor prevents acute antibody-mediated rejection in alloimmunized baboons
    • Tillou X, Poirier N, Le Bas-Bernardet S, Hervouet J, Minault D, Renaudin K et al (2010) Recombinant human C1-inhibitor prevents acute antibody-mediated rejection in alloimmunized baboons. Kidney Int 78(2):152-1599
    • (2010) Kidney Int , vol.78 , Issue.2 , pp. 152-1599
    • Tillou, X.1    Poirier, N.2    Le Bas-Bernardet, S.3    Hervouet, J.4    Minault, D.5    Renaudin, K.6
  • 150
    • 78650806319 scopus 로고    scopus 로고
    • Attenuation of cross-talk between the complement and coagulation cascades by C5a blockade improves early outcomes after intraportal islet transplantation
    • Tokodai K, Goto M, Inagaki A, Nakanishi W, Ogawa N, Satoh K et al (2010) Attenuation of cross-talk between the complement and coagulation cascades by C5a blockade improves early outcomes after intraportal islet transplantation. Transplantation 90(12):1358-13655
    • (2010) Transplantation , vol.90 , Issue.12 , pp. 1358-13655
    • Tokodai, K.1    Goto, M.2    Inagaki, A.3    Nakanishi, W.4    Ogawa, N.5    Satoh, K.6
  • 151
    • 58849109079 scopus 로고    scopus 로고
    • 3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase
    • Torreira E, Tortajada A, Montes T, Rodriguez de Cordoba S, Llorca O (2009) 3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase. Proc Natl Acad Sci USA 106(3):882-8877
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.3 , pp. 882-8877
    • Torreira, E.1    Tortajada, A.2    Montes, T.3    Rodriguez De Cordoba, S.4    Llorca, O.5
  • 152
    • 81055157901 scopus 로고    scopus 로고
    • The new era of C1-esterase inhibitor Deficiency therapy
    • Tourangeau LM, Zuraw BL (2011) The new era of C1-esterase inhibitor Deficiency therapy. Curr Allergy Asthma Rep 11(5):345-3511
    • (2011) Curr Allergy Asthma Rep , vol.11 , Issue.5 , pp. 345-3511
    • Tourangeau, L.M.1    Zuraw, B.L.2
  • 153
    • 83155172386 scopus 로고    scopus 로고
    • Eculizumab in atypical hemolytic uremic syndrome: Long-term clinical course and histological fi ndings
    • Tschumi S, Gugger M, Bucher BS, Riedl M, Simonetti GD (2011) Eculizumab in atypical hemolytic uremic syndrome: long-term clinical course and histological fi ndings. Pediatr Nephrol 26(11):2085-20888
    • (2011) Pediatr Nephrol , vol.26 , Issue.11 , pp. 2085-20888
    • Tschumi, S.1    Gugger, M.2    Bucher, B.S.3    Riedl, M.4    Simonetti, G.D.5
  • 154
    • 79955533554 scopus 로고    scopus 로고
    • A crystal structure of the complex between human complement receptor 2 and its ligand C3d
    • van den Elsen JM, Isenman DE (2011) A crystal structure of the complex between human complement receptor 2 and its ligand C3d. Science 332(6029):608-6111
    • (2011) Science , vol.332 , Issue.6029 , pp. 608-6111
    • Van Den Elsen, J.M.1    Isenman, D.E.2
  • 155
    • 77957104721 scopus 로고    scopus 로고
    • Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in a porcine ischemia-reperfusion model
    • van der Pals J, Koul S, Andersson P, Gotberg M, Ubachs JF, Kanski M et al (2010) Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in a porcine ischemia-reperfusion model. BMC Cardiovasc Disord 10:455
    • (2010) BMC Cardiovasc Disord , vol.10 , pp. 455
    • Van Der Pals, J.1    Koul, S.2    Andersson, P.3    Gotberg, M.4    Ubachs, J.F.5    Kanski, M.6
  • 157
    • 77957916119 scopus 로고    scopus 로고
    • Cobra venom factor: Structure, function, and humanization for therapeutic complement depletion
    • Vogel CW, Fritzinger DC (2010) Cobra venom factor: structure, function, and humanization for therapeutic complement depletion. Toxicon 56(7):1198-12222
    • (2010) Toxicon , vol.56 , Issue.7 , pp. 1198-12222
    • Vogel, C.W.1    Fritzinger, D.C.2
  • 158
    • 79151471122 scopus 로고    scopus 로고
    • AHUS caused by complement dysregulation: New therapies on the horizon
    • Waters AM, Licht C (2011) aHUS caused by complement dysregulation: new therapies on the horizon. Pediatr Nephrol 26(1):41-577
    • (2011) Pediatr Nephrol , vol.26 , Issue.1 , pp. 41-577
    • Waters, A.M.1    Licht, C.2
  • 159
    • 37249004920 scopus 로고    scopus 로고
    • Reaching for high-hanging fruit in drug discovery at protein-protein interfaces
    • Wells JA, McClendon CL (2007) Reaching for high-hanging fruit in drug discovery at protein-protein interfaces. Nature 450(7172):1001-10099
    • (2007) Nature , vol.450 , Issue.7172 , pp. 1001-10099
    • Wells, J.A.1    McClendon, C.L.2
  • 160
    • 33750873601 scopus 로고    scopus 로고
    • Structure of C3b in complex with CRIg gives insights into regulation of complement activation
    • Wiesmann C, Katschke KJ, Yin J, Helmy KY, Steffek M, Fairbrother WJ et al (2006) Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature 444(7116):217-2200
    • (2006) Nature , vol.444 , Issue.7116 , pp. 217-2200
    • Wiesmann, C.1    Katschke, K.J.2    Yin, J.3    Helmy, K.Y.4    Steffek, M.5    Fairbrother, W.J.6
  • 161
  • 162
    • 67649230210 scopus 로고    scopus 로고
    • Structure of complement fragment C3b-factor H and implications for host protection by complement regulators
    • Wu J, Wu YQ, Ricklin D, Janssen BJ, Lambris JD, Gros P (2009) Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nat Immunol 10(7):728-7333
    • (2009) Nat Immunol , vol.10 , Issue.7 , pp. 728-7333
    • Wu, J.1    Wu, Y.Q.2    Ricklin, D.3    Janssen, B.J.4    Lambris, J.D.5    Gros, P.6
  • 163
    • 79954997898 scopus 로고    scopus 로고
    • Protection of nonself surfaces from complement attack by factor H-binding peptides: Implications for therapeutic medicine
    • Wu YQ, Qu H, Sfyroera G, Tzekou A, Kay BK, Nilsson B et al (2011) Protection of nonself surfaces from complement attack by factor H-binding peptides: implications for therapeutic medicine. J Immunol 186(7):4269-42777
    • (2011) J Immunol , vol.186 , Issue.7 , pp. 4269-42777
    • Wu, Y.Q.1    Qu, H.2    Sfyroera, G.3    Tzekou, A.4    Kay, B.K.5    Nilsson, B.6
  • 164
    • 79957594942 scopus 로고    scopus 로고
    • Current clinical trials in dry AMD and the de finition of appropriate clinical outcome measures
    • Yehoshua Z, Rosenfeld PJ, Albini TA (2011) Current clinical trials in dry AMD and the de finition of appropriate clinical outcome measures. Semin Ophthalmol 26(3):167-1800
    • (2011) Semin Ophthalmol , vol.26 , Issue.3 , pp. 167-1800
    • Yehoshua, Z.1    Rosenfeld, P.J.2    Albini, T.A.3
  • 165
    • 79961061340 scopus 로고    scopus 로고
    • C1-inhibitor: More than a serine protease inhibitor
    • Zeerleder S (2011) C1-inhibitor: more than a serine protease inhibitor. Semin Thromb Hemost 37(4):362-3744
    • (2011) Semin Thromb Hemost , vol.37 , Issue.4 , pp. 362-3744
    • Zeerleder, S.1
  • 166
    • 0025122303 scopus 로고
    • Complement activation and the prognostic value of C3a in patients at risk of adult respiratory distress syndrome
    • Zilow G, Sturm JA, Rother U, Kirschfink M (1990) Complement activation and the prognostic value of C3a in patients at risk of adult respiratory distress syndrome. Clin Exp Immunol 79(2):151-1577
    • (1990) Clin Exp Immunol , vol.79 , Issue.2 , pp. 151-1577
    • Zilow, G.1    Sturm, J.A.2    Rother Kirschfink, U.M.3
  • 167
    • 84934438875 scopus 로고    scopus 로고
    • The new chimeric alternative complement inhibitor COMP-CFH15-20 protects surfaces from complement-mediated damage (conference abstract
    • Zipfel PF, Lauer NL, Ricklin D, Heinen SH, Dahse HMD, Tzekou A et al (2011) The new chimeric alternative complement inhibitor COMP-CFH15-20 protects surfaces from complement-mediated damage (conference abstract). Mol Immunol 48(14):17133
    • (2011) Mol Immunol , vol.48 , Issue.14 , pp. 17133
    • Zipfel, P.F.1    Lauer, N.L.2    Ricklin, D.3    Heinen, S.H.4    Dahse, H.M.D.5    Tzekou, A.6


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