-
1
-
-
0344676389
-
An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice
-
DOI 10.1038/nm950
-
Ambati J, Anand A, Fernandez S, Sakurai E, Lynn BC, Kuziel WA, Rollins BJ, Ambati BK (2003) An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice. Nat Med 9:1390-1397 (Pubitemid 37466188)
-
(2003)
Nature Medicine
, vol.9
, Issue.11
, pp. 1390-1397
-
-
Ambati, J.1
Anand, A.2
Fernandez, S.3
Sakurai, E.4
Lynn, B.C.5
Kuziel, W.A.6
Rollins, B.J.7
Ambati, B.K.8
-
2
-
-
33751011889
-
HTRA1 promoter polymorphism in wet age-related macular degeneration
-
DOI 10.1126/science.1133807
-
Dewan A, Liu M, Hartman S, Zhang SS, Liu DT, Zhao C, Tam PO, Chan WM, Lam DS, Snyder M, Barnstable C, Pang CP, Hoh J (2006) HTRA1 promoter polymorphism in wet age-related macular degeneration. Science 314:989-992 (Pubitemid 44749943)
-
(2006)
Science
, vol.314
, Issue.5801
, pp. 989-992
-
-
DeWan, A.1
Liu, M.2
Hartman, S.3
Zhang, S.S.-M.4
Liu, D.T.L.5
Zhao, C.6
Tam, P.O.S.7
Chan, W.M.8
Lam, D.S.C.9
Snyder, M.10
Barnstable, C.11
Pang, C.P.12
Hoh, J.13
-
3
-
-
17244379811
-
Complement factor H polymorphism and age-related macular degeneration
-
DOI 10.1126/science.1110189
-
Edwards AO, Ritter R 3rd, Abel KJ, Manning A, Panhuysen C, Farrer LA (2005) Complement factor H polymorphism and age-related macular degeneration. Science 308:421-424 (Pubitemid 40530082)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 421-424
-
-
Edwards, A.O.1
Ritter III, R.2
Abel, K.J.3
Manning, A.4
Panhuysen, C.5
Farrer, L.A.6
-
5
-
-
33645419787
-
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
-
Gold B, Merriam JE, Zernant J, Hancox LS, Taiber AJ, Gehrs K, Cramer K, Neel J, Bergeron J, Barile GR, Smith RT, AMD Genetics Clinical Study Group, Hageman GS, Dean M, Allikmets R (2006) Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet 38:458-462
-
(2006)
Nat Genet
, vol.38
, pp. 458-462
-
-
Gold, B.1
Merriam, J.E.2
Zernant, J.3
Hancox, L.S.4
Taiber, A.J.5
Gehrs, K.6
Cramer, K.7
Neel, J.8
Bergeron, J.9
Barile, G.R.10
Smith, R.T.11
Hageman, G.S.12
Dean, M.13
Allikmets, R.14
-
6
-
-
76849099044
-
Genetic analysis of typical wet-type age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese population
-
Goto A, Akahori M, Okamoto H, Minami M, Terauchi N, Haruhata Y, Obazawa M, Noda T, Honda M, Mizota A, Tanaka M, Hayashi T, Tanito M, Ogata N, Iwata T (2009) Genetic analysis of typical wet-type age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese population. J Biochem Dis Inform 2(4):164-175
-
(2009)
J Biochem Dis Inform
, vol.2
, Issue.4
, pp. 164-175
-
-
Goto, A.1
Akahori, M.2
Okamoto, H.3
Minami, M.4
Terauchi, N.5
Haruhata, Y.6
Obazawa, M.7
Noda, T.8
Honda, M.9
Mizota, A.10
Tanaka, M.11
Hayashi, T.12
Tanito, M.13
Ogata, N.14
Iwata, T.15
-
7
-
-
33745728418
-
No association between complement factor H gene polymorphism and exudative age-related macular degeneration in Japanese
-
Gotoh N, Yamada R, Hiratani H, Renault V, Kuroiwa S, Monet M, Toyoda S, Chida S, Mandai M, Otani A, Yoshimura N, Matsuda F (2006) No association between complement factor H gene polymorphism and exudative age-related macular degeneration in Japanese. Hum Genet 120:139-143
-
(2006)
Hum Genet
, vol.120
, pp. 139-143
-
-
Gotoh, N.1
Yamada, R.2
Hiratani, H.3
Renault, V.4
Kuroiwa, S.5
Monet, M.6
Toyoda, S.7
Chida, S.8
Mandai, M.9
Otani, A.10
Yoshimura, N.11
Matsuda, F.12
-
8
-
-
21044453724
-
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
-
DOI 10.1073/pnas.0501536102
-
Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI, Hageman JL, Stockman HA, Borchardt JD, Gehrs KM, Smith RJ, Silvestri G, Russell SR, Klaver CC, Barbazetto I, Chang S, Yannuzzi LA, Barile GR, Merriam JC, Smith RT, Olsh AK, Bergeron J, Zernant J, Merriam JE, Gold B, Dean M, Allikmets R (2005) A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci USA 102:7227-7232 (Pubitemid 40696361)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.20
, pp. 7227-7232
-
-
Hageman, G.S.1
Anderson, D.H.2
Johnson, L.V.3
Hancox, L.S.4
Taiber, A.J.5
Hardisty, L.I.6
Hageman, J.L.7
Stockman, H.A.8
Borchardt, J.D.9
Gehrs, K.M.10
Smith, R.J.H.11
Silvestri, G.12
Russell, S.R.13
Klaver, C.C.W.14
Barbazetto, I.15
Chang, S.16
Yannuzzi, L.A.17
Barile, G.R.18
Merriam, J.C.19
Smith, R.T.20
Olsh, A.K.21
Bergeron, J.22
Zernant, J.23
Merriam, J.E.24
Gold, B.25
Dean, M.26
Allikmets, R.27
more..
-
9
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
DOI 10.1126/science.1110359
-
Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine M, Gilbert JR, Schnetz-Boutaud N, Agarwal A, Postel EA, Pericak-Vance MA (2005) Complement factor H variant increases the risk of age-related macular degeneration. Science 308:419-421 (Pubitemid 40530081)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 419-421
-
-
Haines, J.L.1
Hauser, M.A.2
Schmidt, S.3
Scott, W.K.4
Olson, L.M.5
Gallins, P.6
Spencer, K.L.7
Shu, Y.K.8
Noureddine, M.9
Gilbert, J.R.10
Schnetz-Boutaud, N.11
Agarwal, A.12
Postel, E.A.13
Pericak-Vance, M.A.14
-
10
-
-
9144228044
-
Dissection of Genomewide-Scan Data in Extended Families Reveals a Major Locus and Oligogenic Susceptibility for Age-Related Macular Degeneration
-
DOI 10.1086/380912
-
Iyengar SK, Song D, Klein BE, Klein R, Schick JH, Humphrey J, Millard C, Liptak R, Russo K, Jun G, Lee KE, Fijal B, Elston RC (2004) Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet 74:20-39 (Pubitemid 38085235)
-
(2004)
American Journal of Human Genetics
, vol.74
, Issue.1
, pp. 20-39
-
-
Iyengar, S.K.1
Song, D.2
Klein, B.E.K.3
Klein, R.4
Schick, J.H.5
Humphrey, J.6
Millard, C.7
Liptak, R.8
Russo, K.9
Jun, G.10
Lee, K.E.11
Fijal, B.12
Elston, R.C.13
-
11
-
-
33746735499
-
Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin
-
DOI 10.1021/jm0603419
-
Katragadda M, Magotti P, Sfyroera G, Lambris JD (2006) Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin. J Med Chem 49:4616-4622 (Pubitemid 44162688)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.15
, pp. 4616-4622
-
-
Katragadda, M.1
Magotti, P.2
Sfyroera, G.3
Lambris, J.D.4
-
12
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
DOI 10.1126/science.1109557
-
Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308:385-389 (Pubitemid 40530070)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.-Y.4
Sackler, R.S.5
Haynes, C.6
Henning, A.K.7
SanGiovanni, J.P.8
Mane, S.M.9
Mayne, S.T.10
Bracken, M.B.11
Ferris, F.L.12
Ott, J.13
Barnstable, C.14
Hoh, J.15
-
13
-
-
0041886495
-
Age-related macular degeneration - A genome scan in extended families
-
DOI 10.1086/377701
-
Majewski J, Schultz DW, Weleber RG, Schain MB, Edwards AO, Matise TC, Acott TS, Ott J, Klein ML (2003) Age-related macular degeneration - a genome scan in extended families. Am J Hum Genet 73:540-550 (Pubitemid 37076268)
-
(2003)
American Journal of Human Genetics
, vol.73
, Issue.3
, pp. 540-550
-
-
Majewski, J.1
Schultz, D.W.2
Weleber, R.G.3
Schain, M.B.4
Edwards, A.O.5
Matise, T.C.6
Acott, T.S.7
Ott, J.8
Klein, M.L.9
-
14
-
-
0034012166
-
Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
-
Mullins RF, Russell SR, Anderson DH, Hageman GS (2000) Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. FASEB J 14:835-846 (Pubitemid 30241660)
-
(2000)
FASEB Journal
, vol.14
, Issue.7
, pp. 835-846
-
-
Mullins, R.F.1
Russell, S.R.2
Anderson, D.H.3
Hageman, G.S.4
-
15
-
-
0029922872
-
Studies on the mechanism of early onset macular degeneration in cynomolgus (Macaca fascicularis) monkeys. I. Abnormal concentrations of two proteins in the retina
-
DOI 10.1006/exer.1996.0026
-
Nicolas MG, Fujiki K, Murayama K, Suzuki MT, Mineki R, Hayakawa M, Yoshikawa Y, Cho F, Kanai A (1996a) Studies on the mechanism of early onset macular degeneration in cynomolgus (Macaca fascicularis) monkeys. I. Abnormal concentrations of two proteins in the retina. Exp Eye Res 62:211-219 (Pubitemid 26127997)
-
(1996)
Experimental Eye Research
, vol.62
, Issue.3
, pp. 211-219
-
-
Nicolas, M.G.1
Fujiki, K.2
Murayama, K.3
Suzuki, M.T.4
Mineki, R.5
Hayakawa, M.6
Yoshikawa, Y.7
Cho, F.8
Kanai, A.9
-
16
-
-
0029936705
-
Studies on the mechanism of early onset macular degeneration in cynomolgus monkeys. II. Suppression of metallothionein synthesis in the retina in oxidative stress
-
DOI 10.1006/exer.1996.0045
-
Nicolas MG, Fujiki K, Murayama K, Suzuki MT, Shindo N, Hotta Y, Iwata F, Fujimura T, Yoshikawa Y, Cho F, Kanai A (1996b) Studies on the mechanism of early onset macular degeneration in cynomolgus monkeys. II. Suppression of metallothionein synthesis in the retina in oxidative stress. Exp Eye Res 62:399-408 (Pubitemid 26150373)
-
(1996)
Experimental Eye Research
, vol.62
, Issue.4
, pp. 399-408
-
-
Nicolas, M.G.1
Fujiki, K.2
Murayama, K.3
Suzuki, M.T.4
Shindo, N.5
Hotta, Y.6
Iwata, F.7
Fujimura, T.8
Yoshikawa, Y.9
Cho, F.10
Kanai, A.11
-
17
-
-
33644676878
-
Complement factor H polymorphisms in Japanese population with age-related macular degeneration
-
Okamoto H, Umeda S, Obazawa M, Minami M, Noda T, Mizota A, Honda M, Tanaka M, Koyama R, Takagi I, Sakamoto Y, Saito Y, Miyake Y, Iwata T (2006) Complement factor H polymorphisms in Japanese population with age-related macular degeneration. Mol Vis 12:156-158 (Pubitemid 43329568)
-
(2006)
Molecular Vision
, vol.12
, pp. 156-158
-
-
Okamoto, H.1
Umeda, S.2
Obazawa, M.3
Minami, M.4
Noda, T.5
Mizota, A.6
Honda, M.7
Tanaka, M.8
Koyama, R.9
Takagi, I.10
Sakamoto, Y.11
Saito, Y.12
Miyake, Y.13
Iwata, T.14
-
18
-
-
0033968180
-
Location, substructure, and composition of basal laminar drusen compared with drusen associated with aging and age-related macular degeneration
-
DOI 10.1016/S0002-9394(99)00345-1, PII S0002939499003451
-
Russell SR, Mullins RF, Schneider BL, Hageman GS (2000) Location, substructure, and composition of basal laminar drusen compared with drusen associated with aging and age-related macular degeneration. Am J Ophthalmol 129:205-214 (Pubitemid 30089281)
-
(2000)
American Journal of Ophthalmology
, vol.129
, Issue.2
, pp. 205-214
-
-
Russell, S.R.1
Mullins, R.F.2
Schneider, B.L.3
Hageman, G.S.4
-
19
-
-
0037677746
-
A whole-genome screen of a quantitative trait of age-related maculopathy in sibships from the Beaver Dam Eye Study
-
DOI 10.1086/375500
-
Schick JH, Iyengar SK, Klein BE, Klein R, Reading K, Liptak R, Millard C, Lee KE, Tomany SC, Moore EL, Fijal BA, Elston RC (2003) A whole-genome screen of a quantitative trait of agerelated maculopathy in sibships from the Beaver Dam Eye Study. Am J Hum Genet 72:1412-1424 (Pubitemid 36628381)
-
(2003)
American Journal of Human Genetics
, vol.72
, Issue.6
, pp. 1412-1424
-
-
Schick, J.H.1
Iyengar, S.K.2
Klein, B.E.3
Klein, R.4
Reading, K.5
Liptak, R.6
Millard, C.7
Lee, K.E.8
Tomany, S.C.9
Moore, E.L.10
Fijal, B.A.11
Elston, R.C.12
-
20
-
-
0021361247
-
Spontaneous degenerative maculopathy in the monkey
-
Stafford TJ, Anness SH, Fine BS (1984) Spontaneous degenerative maculopathy in the monkey. Ophthalmology 91:513-521 (Pubitemid 14149082)
-
(1984)
Ophthalmology
, vol.91
, Issue.5
, pp. 513-521
-
-
Stafford, T.J.1
Anness, S.H.2
Fine, B.S.3
-
21
-
-
0041349303
-
Familial early onset macular degeneration in cynomolgus monkeys (Macaca fascicularis)
-
DOI 10.1007/s10329-002-0016-6
-
Suzuki MT, Terao K, Yoshikawa Y (2003) Familial early onset macular degeneration in cynomolgus monkeys (Macaca fascicularis). Primates 44:291-294 (Pubitemid 37182000)
-
(2003)
Primates
, vol.44
, Issue.3
, pp. 291-294
-
-
Suzuki, M.T.1
Terao, K.2
Yoshikawa, Y.3
-
22
-
-
13944258942
-
Early-onset macular degeneration with drusen in a cynomolgus monkey (Macaca fascicularis) pedigree: Exclusion of 13 candidate genes and loci
-
DOI 10.1167/iovs.04-1031
-
Umeda S, Ayyagari R, Allikmets R, Suzuki MT, Karoukis AJ, Ambasudhan R, Zernant J, Okamoto H, Ono F, Terao K, Mizota A, Yoshikawa Y, Tanaka Y, Iwata T (2005a) Early-onset macular degeneration with drusen in a cynomolgus monkey (Macaca fascicularis) pedigree: exclusion of 13 candidate genes and loci. Invest Ophthalmol Vis Sci 46:683-691 (Pubitemid 40270353)
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, Issue.2
, pp. 683-691
-
-
Umeda, S.1
Ayyagari, R.2
Allikmets, R.3
Suzuki, M.T.4
Karoukis, A.J.5
Ambasudhan, R.6
Zernant, J.7
Okamoto, H.8
Ono, F.9
Terao, K.10
Mizota, A.11
Yoshikawa, Y.12
Tanaka, Y.13
Iwata, T.14
-
23
-
-
26444583909
-
Molecular composition of drusen and possible involvement of anti-retinal autoimmunity in two different forms of macular degeneration in cynomolgus monkey (Macaca fascicularis)
-
DOI 10.1096/fj.05-3525fje
-
Umeda S, Suzuki MT, Okamoto H, Ono F, Mizota A, Terao K, Yoshikawa Y, Tanaka Y, Iwata T(2005b) Molecular composition of drusen and possible involvement of anti-retinal autoimmunity in two different forms of macular degeneration in cynomolgus monkey (Macaca fascicularis). FASEB J 19:1683-1685 (Pubitemid 41429529)
-
(2005)
FASEB Journal
, vol.19
, Issue.12
, pp. 1683-1685
-
-
Umeda, S.1
Suzuki, M.T.2
Okamoto, H.3
Ono, F.4
Mizota, A.5
Terao, K.6
Yoshikawa, Y.7
Tanaka, Y.8
Iwata, T.9
-
24
-
-
33751004690
-
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration
-
DOI 10.1126/science.1133811
-
Yang Z, Camp NJ, Sun H, Tong Z, Gibbs D, Cameron DJ, Chen H, Zhao Y, Pearson E, Li X, Chien J, Dewan A, Harmon J, Bernstein PS, Shridhar V, Zabriskie NA, Hoh J, Howes K, Zhang K (2006) A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science 314:992-993 (Pubitemid 44749944)
-
(2006)
Science
, vol.314
, Issue.5801
, pp. 992-993
-
-
Yang, Z.1
Camp, N.J.2
Sun, H.3
Tong, Z.4
Gibbs, D.5
Cameron, D.J.6
Chen, H.7
Zhao, Y.8
Pearson, E.9
Li, X.10
Chien, J.11
DeWan, A.12
Harmon, J.13
Bernstein, P.S.14
Shridhar, V.15
Zabriskie, N.A.16
Hoh, J.17
Howes, K.18
Zhang, K.19
-
25
-
-
34547764305
-
Complement C3 variant and the risk of age-related macular degeneration
-
DOI 10.1056/NEJMoa072618
-
Yates JRW, Sepp T, Matharu BK, Khan JC, Thurlby DA, Shahid H, Clayton DG, Hayward C, Morgan J, Wright AF, Armbrecht AM, Dhillon B, Deary IJ, Redmond E, Bird AC, Moore AT (2007) Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med 357:553-561 (Pubitemid 47236280)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.6
, pp. 553-561
-
-
Yates, J.R.W.1
Sepp, T.2
Matharu, B.K.3
Khan, J.C.4
Thurlby, D.A.5
Shahid, H.6
Clayton, D.G.7
Hayward, C.8
Morgan, J.9
Wright, A.F.10
Armbrecht, A.M.11
Dhillon, B.12
Deary, I.J.13
Redmond, E.14
Bird, A.C.15
Moore, A.T.16
-
26
-
-
34047270761
-
HTRA1 promoter polymorphism predisposes Japanese to AMD
-
Yoshida T, Wan AD, Zhang H, Sakamoto R, Okamoto H, Minami M, Obazawa M, Mizota A, Tanaka M, Saito Y, Takagi I, Hoh J, Iwata T (2007) HTRA1 promoter polymorphism predisposes Japanese to AMD. Mol Vis 13:545-548
-
(2007)
Mol Vis
, vol.13
, pp. 545-548
-
-
Yoshida, T.1
Wan, A.D.2
Zhang, H.3
Sakamoto, R.4
Okamoto, H.5
Minami, M.6
Obazawa, M.7
Mizota, A.8
Tanaka, M.9
Saito, Y.10
Takagi, I.11
Hoh, J.12
Iwata, T.13
|