-
1
-
-
36849044745
-
Translational mini-review series on complement factor H: Structural and functional correlations for factor H
-
Schmidt, C.Q., Herbert, A.P., Hocking, H.G., Uhrin, D. & Barlow, P.N. Translational mini-review series on complement factor H: Structural and functional correlations for factor H. Clin. Exp. Immunol. 151 14-24 (2008).
-
(2008)
Clin. Exp. Immunol
, vol.151
, pp. 14-24
-
-
Schmidt, C.Q.1
Herbert, A.P.2
Hocking, H.G.3
Uhrin, D.4
Barlow, P.N.5
-
2
-
-
0030058570
-
Control of the complement system
-
Liszewski, M.K., Farries, T.C., Lublin, D.M., Rooney, I.A. & Atkinson, J.P. Control of the complement system. Adv. Immunol. 61, 201-283 (1996).
-
(1996)
Adv. Immunol
, vol.61
, pp. 201-283
-
-
Liszewski, M.K.1
Farries, T.C.2
Lublin, D.M.3
Rooney, I.A.4
Atkinson, J.P.5
-
3
-
-
34948910047
-
Structural basis for complement factor H linked age-related macular degeneration
-
Prosser, B.E. et al. Structural basis for complement factor H linked age-related macular degeneration. J. Exp. Med. 204, 2277-2283 (2007).
-
(2007)
J. Exp. Med
, vol.204
, pp. 2277-2283
-
-
Prosser, B.E.1
-
4
-
-
34848886930
-
Loss of self-control in the complement system and innate autoreactivity
-
Meri, S. Loss of self-control in the complement system and innate autoreactivity. Ann. NY Acad. Sci. 1109, 93-105 (2007).
-
(2007)
Ann. NY Acad. Sci
, vol.1109
, pp. 93-105
-
-
Meri, S.1
-
5
-
-
36849084660
-
Translational mini-review series on complement factor H: Genetics and disease associations of human complement factor H
-
de Cordoba, S.R. & de Jorge, E.G. Translational mini-review series on complement factor H: Genetics and disease associations of human complement factor H. Clin. Exp. Immunol. 151, 1-13 (2008).
-
(2008)
Clin. Exp. Immunol
, vol.151
, pp. 1-13
-
-
de Cordoba, S.R.1
de Jorge, E.G.2
-
6
-
-
38349048514
-
Complement evasion by human pathogens
-
Lambris, J.D., Ricklin, D. & Geisbrecht, B.V. Complement evasion by human pathogens. Nat. Rev. Microbiol. 6, 132-142 (2008).
-
(2008)
Nat. Rev. Microbiol
, vol.6
, pp. 132-142
-
-
Lambris, J.D.1
Ricklin, D.2
Geisbrecht, B.V.3
-
7
-
-
67249113222
-
Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates
-
Schneider, M.C. et al. Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates. Nature 458, 890-893 (2009).
-
(2009)
Nature
, vol.458
, pp. 890-893
-
-
Schneider, M.C.1
-
8
-
-
36048937343
-
Complement-targeted therapeutics
-
Ricklin, D. & Lambris, J.D. Complement-targeted therapeutics. Nat. Biotechnol. 25, 1265-1275 (2007).
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 1265-1275
-
-
Ricklin, D.1
Lambris, J.D.2
-
9
-
-
37849036955
-
Translational mini-review series on complement factor H: Therapies of renal diseases associated with complement factor H abnormalities: Atypical haemolytic uraemic syndrome and membranoproliferative glomerulonephritis
-
Noris, M. & Remuzzi, G. Translational mini-review series on complement factor H: Therapies of renal diseases associated with complement factor H abnormalities: Atypical haemolytic uraemic syndrome and membranoproliferative glomerulonephritis. Clin. Exp. Immunol. 151, 199-209 (2008).
-
(2008)
Clin. Exp. Immunol
, vol.151
, pp. 199-209
-
-
Noris, M.1
Remuzzi, G.2
-
10
-
-
0029060511
-
Identification of complement regulatory domains in human factor H
-
Gordon, D.L., Kaufman, R.M., Blackmore, T.K., Kwong, J. & Lublin, D.M. Identification of complement regulatory domains in human factor H. J. Immunol. 155, 348-356 (1995).
-
(1995)
J. Immunol
, vol.155
, pp. 348-356
-
-
Gordon, D.L.1
Kaufman, R.M.2
Blackmore, T.K.3
Kwong, J.4
Lublin, D.M.5
-
11
-
-
53149104792
-
A new map of glycosaminoglycan and C3b binding sites on factor H
-
Schmidt, C.Q. et al. A new map of glycosaminoglycan and C3b binding sites on factor H. J. Immunol. 181, 2610-2619 (2008).
-
(2008)
J. Immunol
, vol.181
, pp. 2610-2619
-
-
Schmidt, C.Q.1
-
12
-
-
44049086967
-
Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations
-
Hocking, H.G. et al. Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J. Biol. Chem. 283, 9475-9487 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 9475-9487
-
-
Hocking, H.G.1
-
13
-
-
36349016373
-
The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties
-
Okemefuna, A.I. et al. The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties. J. Mol. Biol. 375, 80-101 (2008).
-
(2008)
J. Mol. Biol
, vol.375
, pp. 80-101
-
-
Okemefuna, A.I.1
-
14
-
-
33750859976
-
Structure of C3b reveals conformational changes that underlie complement activity
-
Janssen, B.J., Christodoulidou, A., McCarthy, A., Lambris, J.D. & Gros, P. Structure of C3b reveals conformational changes that underlie complement activity. Nature 444, 213-216 (2006).
-
(2006)
Nature
, vol.444
, pp. 213-216
-
-
Janssen, B.J.1
Christodoulidou, A.2
McCarthy, A.3
Lambris, J.D.4
Gros, P.5
-
15
-
-
33750873601
-
Structure of C3b in complex with CRIg gives insights into regulation of complement activation
-
Wiesmann, C. et al. Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature 444 217-220 (2006).
-
(2006)
Nature
, vol.444
, pp. 217-220
-
-
Wiesmann, C.1
-
16
-
-
0026544866
-
Segment spanning residues 727-768 of the complement C3 sequence contains a neoantigenic site and accommodates the binding of CR1, factor H, and factor B
-
Becherer, J.D., Alsenz, J., Esparza, I., Hack, C.E. & Lambris, J.D. Segment spanning residues 727-768 of the complement C3 sequence contains a neoantigenic site and accommodates the binding of CR1, factor H, and factor B. Biochemistry 31, 1787-1794 (1992).
-
(1992)
Biochemistry
, vol.31
, pp. 1787-1794
-
-
Becherer, J.D.1
Alsenz, J.2
Esparza, I.3
Hack, C.E.4
Lambris, J.D.5
-
17
-
-
0030004710
-
Dissection of CR1, factor H, membrane cofactor protein, and factor B binding and functional sites in the third complement component
-
Lambris, J.D. et al. Dissection of CR1, factor H, membrane cofactor protein, and factor B binding and functional sites in the third complement component. J. Immunol. 156, 4821-4832 (1996).
-
(1996)
J. Immunol
, vol.156
, pp. 4821-4832
-
-
Lambris, J.D.1
-
18
-
-
0033582520
-
Identification of residues within the 727-767 segment of human complement component C3 important for its interaction with factor H and with complement receptor 1 (CR1, CD35)
-
Oran, A.E. & Isenman, D.E. Identification of residues within the 727-767 segment of human complement component C3 important for its interaction with factor H and with complement receptor 1 (CR1, CD35). J. Biol. Chem. 274, 5120-5130 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 5120-5130
-
-
Oran, A.E.1
Isenman, D.E.2
-
19
-
-
25644452794
-
Structures of complement component C3 provide insights into the function and evolution of immunity
-
Janssen, B.J. et al. Structures of complement component C3 provide insights into the function and evolution of immunity. Nature 437, 505-511 (2005).
-
(2005)
Nature
, vol.437
, pp. 505-511
-
-
Janssen, B.J.1
-
20
-
-
37549023083
-
Complement driven by conformational changes
-
Gros, P., Milder, F.J. & Janssen, B.J. Complement driven by conformational changes. Nat. Rev. Immunol. 8, 48-58 (2008).
-
(2008)
Nat. Rev. Immunol
, vol.8
, pp. 48-58
-
-
Gros, P.1
Milder, F.J.2
Janssen, B.J.3
-
21
-
-
67649221223
-
-
Rooijakkers, S.H.M. et al. Structural and functional implications of the complement convertase stabilized by a staphylococcal inhibitor. Nat. Immunol. advance online publication, doi:10.1038/ni.1756 (7 June 2009).
-
Rooijakkers, S.H.M. et al. Structural and functional implications of the complement convertase stabilized by a staphylococcal inhibitor. Nat. Immunol. advance online publication, doi:10.1038/ni.1756 (7 June 2009).
-
-
-
-
22
-
-
0037059776
-
Decay-accelerating factor (DAF), complement receptor 1 (CR1), and factor H dissociate the complement AP C3 convertase (C3bBb) via sites on the type A domain of Bb
-
Hourcade, D.E., Mitchell, L., Kuttner-Kondo, L.A., Atkinson, J.P. & Medof, M.E. Decay-accelerating factor (DAF), complement receptor 1 (CR1), and factor H dissociate the complement AP C3 convertase (C3bBb) via sites on the type A domain of Bb. J. Biol. Chem. 277, 1107-1112 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 1107-1112
-
-
Hourcade, D.E.1
Mitchell, L.2
Kuttner-Kondo, L.A.3
Atkinson, J.P.4
Medof, M.E.5
-
23
-
-
10744227090
-
Complement regulation at the molecular level: The structure of decay-accelerating factor
-
Lukacik, P. et al. Complement regulation at the molecular level: the structure of decay-accelerating factor. Proc. Natl. Acad. Sci. USA 101, 1279-1284 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1279-1284
-
-
Lukacik, P.1
-
24
-
-
34547104615
-
Structure-based mapping of DAF active site residues that accelerate the decay of C3 convertases
-
Kuttner-Kondo, L. et al. Structure-based mapping of DAF active site residues that accelerate the decay of C3 convertases. J. Biol. Chem. 282, 18552-18562 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, pp. 18552-18562
-
-
Kuttner-Kondo, L.1
-
25
-
-
13244291613
-
Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55)
-
Harris, C.L., Abbott, R.J., Smith, R.A., Morgan, B.P. & Lea, S.M. Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55). J. Biol. Chem. 280, 2569-2578 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 2569-2578
-
-
Harris, C.L.1
Abbott, R.J.2
Smith, R.A.3
Morgan, B.P.4
Lea, S.M.5
-
26
-
-
34247891506
-
Structural basis of integrin regulation and signaling
-
Luo, B.H., Carman, C.V. & Springer, T.A. Structural basis of integrin regulation and signaling. Annu. Rev. Immunol. 25, 619-647 (2007).
-
(2007)
Annu. Rev. Immunol
, vol.25
, pp. 619-647
-
-
Luo, B.H.1
Carman, C.V.2
Springer, T.A.3
-
27
-
-
33846094404
-
Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome
-
Goicoechea de Jorge, E. et al. Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome. Proc. Natl. Acad. Sci. USA 104, 240-245 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 240-245
-
-
Goicoechea de Jorge, E.1
-
28
-
-
0032104032
-
Interaction of vaccinia virus complement control protein with human complement proteins: Factor I-mediated degradation of C3b to iC3b1 inactivates the alternative complement pathway
-
Sahu, A., Isaacs, S.N., Soulika, A.M. & Lambris, J.D. Interaction of vaccinia virus complement control protein with human complement proteins: Factor I-mediated degradation of C3b to iC3b1 inactivates the alternative complement pathway. J. Immunol. 160, 5596-5604 (1998).
-
(1998)
J. Immunol
, vol.160
, pp. 5596-5604
-
-
Sahu, A.1
Isaacs, S.N.2
Soulika, A.M.3
Lambris, J.D.4
-
29
-
-
0026645955
-
Ultrastructures and interactions of complement factors H and I
-
DiScipio, R.G. Ultrastructures and interactions of complement factors H and I. J. Immunol. 149, 2592-2599 (1992).
-
(1992)
J. Immunol
, vol.149
, pp. 2592-2599
-
-
DiScipio, R.G.1
-
30
-
-
41149162586
-
Identification of hot spots in the variola virus complement inhibitor (SPICE) for human complement regulation
-
Yadav, V.N., Pyaram, K., Mullick, J. & Sahu, A. Identification of hot spots in the variola virus complement inhibitor (SPICE) for human complement regulation. J. Virol. 82, 3283-3294 (2008).
-
(2008)
J. Virol
, vol.82
, pp. 3283-3294
-
-
Yadav, V.N.1
Pyaram, K.2
Mullick, J.3
Sahu, A.4
-
31
-
-
53949113127
-
Functional characterization of human C3/ cobra venom factor hybrid proteins for therapeutic complement depletion
-
Fritzinger, D.C. et al. Functional characterization of human C3/ cobra venom factor hybrid proteins for therapeutic complement depletion. Dev. Comp. Immunol. 33, 105-116 (2009).
-
(2009)
Dev. Comp. Immunol
, vol.33
, pp. 105-116
-
-
Fritzinger, D.C.1
-
32
-
-
33745697887
-
Deletion of Lys224 in regulatory domain 4 of factor H reveals a novel pathomechanism for dense deposit disease (MPGN II)
-
Licht, C. et al. Deletion of Lys224 in regulatory domain 4 of factor H reveals a novel pathomechanism for dense deposit disease (MPGN II). Kidney Int. 70, 42-50 (2006).
-
(2006)
Kidney Int
, vol.70
, pp. 42-50
-
-
Licht, C.1
-
33
-
-
29944439131
-
An interactive web database of factor H-associated hemolytic uremic syndrome mutations: Insights into the structural consequences of disease-associated mutations
-
Saunders, R.E., Goodship, T.H., Zipfel, P.F. & Perkins, S.J. An interactive web database of factor H-associated hemolytic uremic syndrome mutations: Insights into the structural consequences of disease-associated mutations. Hum. Mutat. 27, 21-30 (2006).
-
(2006)
Hum. Mutat
, vol.27
, pp. 21-30
-
-
Saunders, R.E.1
Goodship, T.H.2
Zipfel, P.F.3
Perkins, S.J.4
-
34
-
-
54049137505
-
Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome
-
Fremeaux-Bacchi, V. et al. Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome. Blood 112 4948-4952 (2008).
-
(2008)
Blood
, vol.112
, pp. 4948-4952
-
-
Fremeaux-Bacchi, V.1
-
35
-
-
0242601270
-
Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: The C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease
-
Caprioli, J. et al. Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: The C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease. Hum. Mol. Genet. 12, 3385-3395 (2003).
-
(2003)
Hum. Mol. Genet
, vol.12
, pp. 3385-3395
-
-
Caprioli, J.1
-
36
-
-
21044453724
-
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
-
Hageman, G.S. et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc. Natl. Acad. Sci. USA 102, 7227-7232 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 7227-7232
-
-
Hageman, G.S.1
-
37
-
-
33745716919
-
Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease)
-
Abrera-Abeleda, M.A. et al. Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease). J. Med. Genet. 43, 582-589 (2006).
-
(2006)
J. Med. Genet
, vol.43
, pp. 582-589
-
-
Abrera-Abeleda, M.A.1
-
38
-
-
58849122853
-
Coding variant I62V in the complement factor H gene is strongly associated with polypoidal choroidal vasculopathy
-
Kondo, N., Honda, S., Kuno, S. & Negi, A. Coding variant I62V in the complement factor H gene is strongly associated with polypoidal choroidal vasculopathy. Ophthalmology 116, 304-310 (2009).
-
(2009)
Ophthalmology
, vol.116
, pp. 304-310
-
-
Kondo, N.1
Honda, S.2
Kuno, S.3
Negi, A.4
-
39
-
-
1542318912
-
Heterozygous and homozygous factor h deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: Report and genetic analysis of 16 cases
-
Dragon-Durey, M.A. et al. Heterozygous and homozygous factor h deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: Report and genetic analysis of 16 cases. J. Am. Soc. Nephrol. 15, 787-795 (2004).
-
(2004)
J. Am. Soc. Nephrol
, vol.15
, pp. 787-795
-
-
Dragon-Durey, M.A.1
-
40
-
-
0034531239
-
Dissecting sites important for complement regulatory activity in membrane cofactor protein (MCP; CD46)
-
Liszewski, M.K. et al. Dissecting sites important for complement regulatory activity in membrane cofactor protein (MCP; CD46). J. Biol. Chem. 275, 37692-37701 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 37692-37701
-
-
Liszewski, M.K.1
-
41
-
-
56249140828
-
Age-related macular degeneration
-
Coleman, H.R., Chan, C.C., Ferris, F.L. III & Chew, E.Y. Age-related macular degeneration. Lancet 372, 1835-1845 (2008).
-
(2008)
Lancet
, vol.372
, pp. 1835-1845
-
-
Coleman, H.R.1
Chan, C.C.2
Ferris III, F.L.3
Chew, E.Y.4
-
42
-
-
0019191997
-
Release of endogenous C3b inactivator from lymphocytes in response to triggering membrane receptors for beta 1H globulin
-
Lambris, J.D., Dobson, N.J. & Ross, G.D. Release of endogenous C3b inactivator from lymphocytes in response to triggering membrane receptors for beta 1H globulin. J. Exp. Med. 152, 1625-1644 (1980).
-
(1980)
J. Exp. Med
, vol.152
, pp. 1625-1644
-
-
Lambris, J.D.1
Dobson, N.J.2
Ross, G.D.3
-
43
-
-
33644875355
-
Scaling and assessment of data quality
-
Evans, P. Scaling and assessment of data quality. Acta Crystallographica Section D 62, 72-82 (2006).
-
(2006)
Acta Crystallographica Section D
, vol.62
, pp. 72-82
-
-
Evans, P.1
-
44
-
-
34447508216
-
Phaser crystallographic software
-
McCoy, A.J. et al. Phaser crystallographic software. J. Appl. Crystallogr. 40, 658-674 (2007).
-
(2007)
J. Appl. Crystallogr
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
-
45
-
-
43749083257
-
A program for mutating pdb files used as templates in molecular replacement
-
Stein, N. CHAINSAW: A program for mutating pdb files used as templates in molecular replacement. J. Appl. Crystallogr. 41, 641-643 (2008).
-
(2008)
J. Appl. Crystallogr
, vol.41
, pp. 641-643
-
-
Stein1
CHAINSAW, N.2
-
46
-
-
0033214106
-
Adhesion mechanism of human b2-glycoprotein I to phospholipids based on its crystal structure
-
Bouma, B. et al. Adhesion mechanism of human b2-glycoprotein I to phospholipids based on its crystal structure. EMBO J. 18, 5166-5174 (1999).
-
(1999)
EMBO J
, vol.18
, pp. 5166-5174
-
-
Bouma, B.1
-
48
-
-
0013461295
-
Macromolecular TLS refinement in REFMAC at moderate resolutions
-
Winn, M.D., Murshudov, G.N. & Papiz, M.Z. Macromolecular TLS refinement in REFMAC at moderate resolutions. Methods Enzymol. 374, 300-321 (2003).
-
(2003)
Methods Enzymol
, vol.374
, pp. 300-321
-
-
Winn, M.D.1
Murshudov, G.N.2
Papiz, M.Z.3
-
49
-
-
14244272868
-
PHENIX: Building new software for automated crystallographic structure determination
-
Adams, P.D. et al. PHENIX: Building new software for automated crystallographic structure determination. Acta Crystallogr. D Biol. Crystallogr. 58, 1948-1954 (2002).
-
(2002)
Acta Crystallogr. D Biol. Crystallogr
, vol.58
, pp. 1948-1954
-
-
Adams, P.D.1
-
50
-
-
0021736976
-
Localization of the complement- component-C3b-binding site and the cofactor activity for factor I in the 38kDa tryptic fragment of factor H
-
Alsenz, J., Lambris, J.D., Schulz, T.F. & Dierich, M.P. Localization of the complement- component-C3b-binding site and the cofactor activity for factor I in the 38kDa tryptic fragment of factor H. Biochem. J. 224, 389-398 (1984).
-
(1984)
Biochem. J
, vol.224
, pp. 389-398
-
-
Alsenz, J.1
Lambris, J.D.2
Schulz, T.F.3
Dierich, M.P.4
|