APT070 (Mirococept), a membrane-localised complement inhibitor, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury

British Journal of Pharmacology

Volumn 145, Issue 8, 2005, Pages 1027-1034

  Souza, Danielle G ^a   Esser, Dirk ^b   Bradford, Roberta ^b   Vieira, Angélica T ^a   Teixeira, Mauro M ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b AdProTech plc   (United Kingdom)

Author keywords

Complement; Inflammation; Neutrophils; Systemic inflammatory response syndrome; TNF

Indexed keywords

COMPLEMENT INHIBITOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MIROCOCEPT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; DRUG INHIBITION; DRUG MECHANISM; INFLAMMATION; INTESTINE; INTESTINE ISCHEMIA; LUNG; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; CAPILLARY PERMEABILITY; COMPLEMENT INACTIVATOR PROTEINS; COMPLEMENT SYSTEM PROTEINS; CYTOKINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROENTERITIS; HEMOGLOBINS; INTESTINES; LEUKOCYTE COUNT; LEUKOCYTES; MALE; NEUTROPHILS; RATS; RATS, WISTAR; REPERFUSION INJURY;

EID: 30544432914     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706286     Document Type: Article

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