Neddylation Promotes Ubiquitylation and Release of Ku from DNA-Damage Sites

Cell Reports

Volumn 11, Issue 5, 2015, Pages 704-714

  Brown, Jessica S ^a   Lukashchuk, Natalia ^a   Sczaniecka Clift, Matylda ^a   Britton, Sébastien ^a,b   le Sage, Carlos ^a   Calsou, Patrick ^b   Beli, Petra ^c   Galanty, Yaron ^a   Jackson, Stephen P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c INSTITUTE OF MOLECULAR BIOLOGY IMB   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DOUBLE STRANDED DNA; KU ANTIGEN; NEDD8 PROTEIN; PEVONEDISTAT; ((1S,2S,4R)-4-(4-((1S)-2,3-DIHYDRO-1H-INDEN-1-YLAMINO)-7H-PYRROLO(2,3-D)PYRIMIDIN-7-YL)-2-HYDROXYCYCLOPENTYL)METHYL SULPHAMATE; CELL NUCLEUS ANTIGEN; CYCLOPENTANE DERIVATIVE; DNA BINDING PROTEIN; H2AFX PROTEIN, HUMAN; HISTONE; NEDD8 PROTEIN, HUMAN; PROTEIN BINDING; PYRIMIDINE DERIVATIVE; SMALL INTERFERING RNA; UBE2M PROTEIN, HUMAN; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; XRCC6 PROTEIN, HUMAN;

ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DNA END JOINING REPAIR; DNA REPAIR; DOUBLE STRANDED DNA BREAK; HUMAN; HUMAN CELL; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN MODIFICATION; PROTEIN SECRETION; RADIOSENSITIVITY; UBIQUITINATION; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; DRUG EFFECTS; GENETICS; METABOLISM; PROTEIN TERTIARY STRUCTURE; PROTEOMICS; RADIATION RESPONSE; RNA INTERFERENCE;

MAMMALIA;

ANTIGENS, NUCLEAR; CELL LINE; CELL SURVIVAL; CYCLOPENTANES; DNA DAMAGE; DNA END-JOINING REPAIR; DNA-BINDING PROTEINS; HISTONES; HUMANS; KU AUTOANTIGEN; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEOMICS; PYRIMIDINES; RADIATION, IONIZING; RNA INTERFERENCE; RNA, SMALL INTERFERING; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION; UBIQUITINS;

EID: 84933673434     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.03.058     Document Type: Article

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