Magnolia bioactive constituent 4-O-methylhonokiol prevents the impairment of cardiac insulin signaling and the cardiac pathogenesis in high-fat diet-induced obese mice

International Journal of Biological Sciences

Volumn 11, Issue 8, 2015, Pages 879-891

  Zhang, Zhiguo ^a,b,c   Chen, Jing ^c   Zhou, Shanshan ^a,b,c   Wang, Shudong ^a,b,c   Cai, Xiaohong ^b   Conklin, Daniel J ^d   Kim, Ki Soo ^e   Kim, Ki Ho ^f   Tan, Yi ^b,c   Zheng, Yang ^a   Kim, Young Heui ^g   Cai, Lu ^b,c  

^a THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c KOSAIR CHILDREN'S HOSPITAL   (United States)

^d UNIVERSITY OF LOUISVILLE   (United States)

^e Bioland Biotec HaiMen Co Ltd   (China)

^f KHBios 505 Venture Center   (South Korea)

^g Bioland Ltd   (South Korea)

Author keywords

4 O methylhonokiol; Cardiac insulin signaling; Lipid accumulation; Lipotoxicity; Nrf2; Obesity

Indexed keywords

MAGNOLIA; MUS;

4-O-METHYLHONOKIOL; BIPHENYL DERIVATIVE; INSULIN; LIGNAN;

ANIMAL; BLOOD PRESSURE; C57BL MOUSE; CARDIAC MUSCLE; CHEMISTRY; DRUG EFFECTS; HEART FUNCTION TEST; LIPID DIET; MAGNOLIA; METABOLISM; MOUSE; OBESITY; ORGAN SIZE; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

ANIMALS; BIPHENYL COMPOUNDS; BLOOD PRESSURE; DIET, HIGH-FAT; HEART FUNCTION TESTS; INSULIN; LIGNANS; MAGNOLIA; MICE; MICE, INBRED C57BL; MYOCARDIUM; OBESITY; ORGAN SIZE; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

EID: 84933529553     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.12101     Document Type: Article

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