4-O-methylhonokiol, a PPARγ agonist, inhibits prostate tumour growth: P21-mediated suppression of NF-kB activity

British Journal of Pharmacology

Volumn 168, Issue 5, 2013, Pages 1133-1145

  Lee, N J ^a   Oh, J H ^a   Ban, J O ^a   Shim, J H ^b   Lee, H P ^a   Jung, J K ^a   Ahn, B W ^a   Yoon, D Y ^c   Han, S B ^a   Ham, Y W ^d   Hong, J T ^a  

^a Chungbuk National University   (South Korea)

^b Soonchunhyang University   (South Korea)

^c Konkuk University   (South Korea)

^d Brigham Young University   (United States)

Author keywords

4 O methylhonokiol; cancer cells; growth inhibition; NF B; p21; PPAR

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; 4 O METHYLHONOKIOL; ANTINEOPLASTIC AGENT; CISPLATIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MUTANT PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PROTEIN P21; RETINOBLASTOMA PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING SITE; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL STRAIN; CELL STRAIN LNCAP; CELL STRAIN PC 3; CELL VIABILITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME BINDING; G0 PHASE CELL CYCLE CHECKPOINT; G1 PHASE CELL CYCLE CHECKPOINT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOLECULAR DOCKING; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIPHENYL COMPOUNDS; CELL CYCLE CHECKPOINTS; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; HUMANS; LIGNANS; MALE; MICE; MICE, NUDE; NF-KAPPA B; PPAR GAMMA; PROSTATIC NEOPLASMS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84874275656     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02235.x     Document Type: Article

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