-
1
-
-
0022412302
-
Dynamic knee extension as model for study of isolated exercising muscle in humans
-
Andersen P, Adams RP, Sjøgaard G, Thorboe A & Saltin B (1985). Dynamic knee extension as model for study of isolated exercising muscle in humans. J Appl Physiol 59, 1647-1653.
-
(1985)
J Appl Physiol
, vol.59
, pp. 1647-1653
-
-
Andersen, P.1
Adams, R.P.2
Sjøgaard, G.3
Thorboe, A.4
Saltin, B.5
-
2
-
-
0022472905
-
Effect of metformin on glucose metabolism in mouse soleus muscle
-
Bailey CJ & Puah JA (1986). Effect of metformin on glucose metabolism in mouse soleus muscle. Diabete Metab 12, 212-218.
-
(1986)
Diabete Metab
, vol.12
, pp. 212-218
-
-
Bailey, C.J.1
Puah, J.A.2
-
3
-
-
18144363560
-
5′-AMP-activated protein kinase regulates skeletal muscle glycogen content and ergogenics
-
Barnes BR, Glund S, Long YC, Hjälm G, Andersson L & Zierath JR (2005). 5′-AMP-activated protein kinase regulates skeletal muscle glycogen content and ergogenics. FASEB J 19, 773-779.
-
(2005)
FASEB J
, vol.19
, pp. 773-779
-
-
Barnes, B.R.1
Glund, S.2
Long, Y.C.3
Hjälm, G.4
Andersson, L.5
Zierath, J.R.6
-
4
-
-
4644309036
-
The 5′-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle
-
Barnes BR, Marklund S, Steiler TL, Walter M, Hjälm G, Amarger V, Mahlapuu M, Leng Y, Johansson C, Galuska D, Lindgren K, Abrink M, Stapleton D, Zierath JR & Andersson L (2004). The 5′-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle. J Biol Chem 279, 38441-38447.
-
(2004)
J Biol Chem
, vol.279
, pp. 38441-38447
-
-
Barnes, B.R.1
Marklund, S.2
Steiler, T.L.3
Walter, M.4
Hjälm, G.5
Amarger, V.6
Mahlapuu, M.7
Leng, Y.8
Johansson, C.9
Galuska, D.10
Lindgren, K.11
Abrink, M.12
Stapleton, D.13
Zierath, J.R.14
Andersson, L.15
-
5
-
-
33947171948
-
Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation
-
Barré L, Richardson C, Hirshman MF, Brozinick J, Fiering S, Kemp BE, Goodyear LJ & Witters LA (2007). Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation. Am J Physiol Endocrinol Metab 292, E802-E811.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
-
-
Barré, L.1
Richardson, C.2
Hirshman, M.F.3
Brozinick, J.4
Fiering, S.5
Kemp, B.E.6
Goodyear, L.J.7
Witters, L.A.8
-
6
-
-
0037160097
-
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1
-
Bitterman KJ, Anderson RM, Cohen HY, Latorre-Esteves M & Sinclair DA (2002). Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J Biol Chem 277, 45099-45107.
-
(2002)
J Biol Chem
, vol.277
, pp. 45099-45107
-
-
Bitterman, K.J.1
Anderson, R.M.2
Cohen, H.Y.3
Latorre-Esteves, M.4
Sinclair, D.A.5
-
7
-
-
15444377466
-
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1
-
Bouras T, Fu M, Sauve AA, Wang F, Quong AA, Perkins ND, Hay RT, Gu W & Pestell RG (2005). SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. J Biol Chem 280, 10264-10276.
-
(2005)
J Biol Chem
, vol.280
, pp. 10264-10276
-
-
Bouras, T.1
Fu, M.2
Sauve, A.A.3
Wang, F.4
Quong, A.A.5
Perkins, N.D.6
Hay, R.T.7
Gu, W.8
Pestell, R.G.9
-
8
-
-
81555204264
-
5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5′-monophosphate-dependent and AMP-activated protein kinase-independent
-
Bumpus NN & Johnson EF (2011). 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5′-monophosphate-dependent and AMP-activated protein kinase-independent. J Pharmacol Exp Ther 339, 886-895.
-
(2011)
J Pharmacol Exp Ther
, vol.339
, pp. 886-895
-
-
Bumpus, N.N.1
Johnson, E.F.2
-
9
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
-
Cantó C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JC, Elliott PJ, Puigserver P & Auwerx J (2009). AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 458, 1056-1060.
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Cantó, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
10
-
-
77249156847
-
Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
-
Cantó C, Jiang LQ, Deshmukh AS, Mataki C, Coste A, Lagouge M, Zierath JR & Auwerx J (2010). Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle. Cell Metab 11, 213-219.
-
(2010)
Cell Metab
, vol.11
, pp. 213-219
-
-
Cantó, C.1
Jiang, L.Q.2
Deshmukh, A.S.3
Mataki, C.4
Coste, A.5
Lagouge, M.6
Zierath, J.R.7
Auwerx, J.8
-
11
-
-
80055051189
-
Metformin opposes impaired AMPK and SIRT1 function and deleterious changes in core clock protein expression in white adipose tissue of genetically-obese db/db mice
-
Caton PW, Kieswich J, Yaqoob MM, Holness MJ & Sugden MC (2011). Metformin opposes impaired AMPK and SIRT1 function and deleterious changes in core clock protein expression in white adipose tissue of genetically-obese db/db mice. Diabetes Obes Metab 13, 1097-1104.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 1097-1104
-
-
Caton, P.W.1
Kieswich, J.2
Yaqoob, M.M.3
Holness, M.J.4
Sugden, M.C.5
-
12
-
-
85047689953
-
5-Aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells
-
amp;
-
Corton JM, Gillespie JG, Hawley SA & Hardie DG (1995). 5-Aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells Eur J Biochem 229, 558-565.
-
(1995)
Eur J Biochem
, vol.229
, pp. 558-565
-
-
Corton, J.M.1
Gillespie, J.G.2
Hawley, S.A.3
Hardie, D.G.4
-
13
-
-
73649133942
-
Skeletal muscle NAMPT is induced by exercise in humans
-
Costford SR, Bajpeyi S, Pasarica M, Albarado DC, Thomas SC, Xie H, Church TS, Jubrias SA, Conley KE & Smith SR (2010). Skeletal muscle NAMPT is induced by exercise in humans. Am J Physiol Endocrinol Metab 298, E117-E126.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Costford, S.R.1
Bajpeyi, S.2
Pasarica, M.3
Albarado, D.C.4
Thomas, S.C.5
Xie, H.6
Church, T.S.7
Jubrias, S.A.8
Conley, K.E.9
Smith, S.R.10
-
14
-
-
0031762953
-
Metformin: a review of its metabolic effects
-
Cusi K & Defronzo RA (1998). Metformin: a review of its metabolic effects. Diabetes Reviews 6, 89-131.
-
(1998)
Diabetes Reviews
, vol.6
, pp. 89-131
-
-
Cusi, K.1
Defronzo, R.A.2
-
15
-
-
34547914840
-
Sirtuins: the "magnificent seven", function, metabolism and longevity
-
Dali-Youcef N, Lagouge M, Froelich S, Koehl C, Schoonjans K & Auwerx J (2007). Sirtuins: the "magnificent seven", function, metabolism and longevity. Ann Med 39, 335-345.
-
(2007)
Ann Med
, vol.39
, pp. 335-345
-
-
Dali-Youcef, N.1
Lagouge, M.2
Froelich, S.3
Koehl, C.4
Schoonjans, K.5
Auwerx, J.6
-
16
-
-
60349123753
-
Reporting ethical matters in The Journal of Physiology: standards and advice
-
Drummond GB (2009). Reporting ethical matters in The Journal of Physiology: standards and advice. J Physiol 587, 713-719.
-
(2009)
J Physiol
, vol.587
, pp. 713-719
-
-
Drummond, G.B.1
-
17
-
-
84873378527
-
Exercise metabolism and the molecular regulation of skeletal muscle adaptation
-
Egan B & Zierath JR (2013). Exercise metabolism and the molecular regulation of skeletal muscle adaptation. Cell Metab 17, 162-184.
-
(2013)
Cell Metab
, vol.17
, pp. 162-184
-
-
Egan, B.1
Zierath, J.R.2
-
18
-
-
1442276288
-
5′-AMP-activated protein kinase activity and protein expression are regulated by endurance training in human skeletal muscle
-
Frøsig C, Jørgensen SB, Hardie DG, Richter EA & Wojtaszewski JFP (2004). 5′-AMP-activated protein kinase activity and protein expression are regulated by endurance training in human skeletal muscle. Am J Physiol Endocrinol Metab 286, E411-E417.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.286
-
-
Frøsig, C.1
Jørgensen, S.B.2
Hardie, D.G.3
Richter, E.A.4
Wojtaszewski, J.F.P.5
-
19
-
-
58149348480
-
Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice
-
Fujii N, Ho RC, Manabe Y, Jessen N, Toyoda T, Holland WL, Summers SA, Hirshman MF & Goodyear LJ (2008). Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice. Diabetes 57, 2958-2966.
-
(2008)
Diabetes
, vol.57
, pp. 2958-2966
-
-
Fujii, N.1
Ho, R.C.2
Manabe, Y.3
Jessen, N.4
Toyoda, T.5
Holland, W.L.6
Summers, S.A.7
Hirshman, M.F.8
Goodyear, L.J.9
-
20
-
-
43049121395
-
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
-
Fulco M, Cen Y, Zhao P, Hoffman EP, McBurney MW, Sauve AA & Sartorelli V (2008). Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev Cell 14, 661-673.
-
(2008)
Dev Cell
, vol.14
, pp. 661-673
-
-
Fulco, M.1
Cen, Y.2
Zhao, P.3
Hoffman, E.P.4
McBurney, M.W.5
Sauve, A.A.6
Sartorelli, V.7
-
21
-
-
62649156291
-
Nampt: linking NAD biology, metabolism and cancer
-
Garten A, Petzold S, Körner A, Imai S-I & Kiess W (2009). Nampt: linking NAD biology, metabolism and cancer. Trends Endocrinol Metab 20, 130-138.
-
(2009)
Trends Endocrinol Metab
, vol.20
, pp. 130-138
-
-
Garten, A.1
Petzold, S.2
Körner, A.3
Imai, S.-I.4
Kiess, W.5
-
22
-
-
0032704115
-
Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
-
Holmes BF, Kurth-Kraczek EJ & Winder WW (1999). Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle. J Appl Physiol 87, 1990-1995.
-
(1999)
J Appl Physiol
, vol.87
, pp. 1990-1995
-
-
Holmes, B.F.1
Kurth-Kraczek, E.J.2
Winder, W.W.3
-
23
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
-
Jäger S, Handschin C, St-Pierre J & Spiegelman BM (2007). AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci U S A 104, 12017-12022.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12017-12022
-
-
Jäger, S.1
Handschin, C.2
St-Pierre, J.3
Spiegelman, B.M.4
-
24
-
-
33745221937
-
Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise
-
Jørgensen SB, Richter EA & Wojtaszewski JFP (2006). Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise. J Physiol 574, 17-31.
-
(2006)
J Physiol
, vol.574
, pp. 17-31
-
-
Jørgensen, S.B.1
Richter, E.A.2
Wojtaszewski, J.F.P.3
-
25
-
-
33846012164
-
Role of AMPKα2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle
-
Jørgensen SB, Treebak JT, Viollet B, Schjerling P, Vaulont S, Wojtaszewski JFP & Richter EA (2007). Role of AMPKα2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle. Am J Physiol Endocrinol Metab 292, E331-E339.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
-
-
Jørgensen, S.B.1
Treebak, J.T.2
Viollet, B.3
Schjerling, P.4
Vaulont, S.5
Wojtaszewski, J.F.P.6
Richter, E.A.7
-
26
-
-
21744463063
-
Effects of α-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle
-
Jørgensen SB, Wojtaszewski JFP, Viollet B, Andreelli F, Birk JB, Hellsten Y, Schjerling P, Vaulont S, Neufer PD, Richter EA & Pilegaard H (2005). Effects of α-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle. FASEB J 19, 1146-1148.
-
(2005)
FASEB J
, vol.19
, pp. 1146-1148
-
-
Jørgensen, S.B.1
Wojtaszewski, J.F.P.2
Viollet, B.3
Andreelli, F.4
Birk, J.B.5
Hellsten, Y.6
Schjerling, P.7
Vaulont, S.8
Neufer, P.D.9
Richter, E.A.10
Pilegaard, H.11
-
27
-
-
33751013309
-
Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3
-
Koh H-J, Arnolds DE, Fujii N, Tran TT, Rogers MJ, Jessen N, Li Y, Liew CW, Ho RC, Hirshman MF, Kulkarni RN, Kahn CR & Goodyear LJ (2006). Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3. Mol Cell Biol 26, 8217-8227.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 8217-8227
-
-
Koh, H.-J.1
Arnolds, D.E.2
Fujii, N.3
Tran, T.T.4
Rogers, M.J.5
Jessen, N.6
Li, Y.7
Liew, C.W.8
Ho, R.C.9
Hirshman, M.F.10
Kulkarni, R.N.11
Kahn, C.R.12
Goodyear, L.J.13
-
29
-
-
84876351263
-
AMP-activated protein kinase regulates endothelial cell angiotensin-converting enzyme expression via p53 and the post-transcriptional regulation of microRNA-143/145
-
Kohlstedt K, Trouvain C, Boettger T, Shi L, Fisslthaler B & Fleming I (2013). AMP-activated protein kinase regulates endothelial cell angiotensin-converting enzyme expression via p53 and the post-transcriptional regulation of microRNA-143/145. Circ Res 112, 1150-1158.
-
(2013)
Circ Res
, vol.112
, pp. 1150-1158
-
-
Kohlstedt, K.1
Trouvain, C.2
Boettger, T.3
Shi, L.4
Fisslthaler, B.5
Fleming, I.6
-
30
-
-
84872311894
-
Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
-
Kristensen JM, Larsen S, Helge JW, Dela F & Wojtaszewski JFP (2013). Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice. PLoS ONE 8, e53533.
-
(2013)
PLoS ONE
, vol.8
-
-
Kristensen, J.M.1
Larsen, S.2
Helge, J.W.3
Dela, F.4
Wojtaszewski, J.F.P.5
-
31
-
-
77956802137
-
PGC-1α is required for AICAR-induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle
-
Leick L, Fentz J, Biensø RS, Knudsen JG, Jeppesen J, Kiens B, Wojtaszewski JFP & Pilegaard H (2010). PGC-1α is required for AICAR-induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle. Am J Physiol Endocrinol Metab 299, E456-E465.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
-
-
Leick, L.1
Fentz, J.2
Biensø, R.S.3
Knudsen, J.G.4
Jeppesen, J.5
Kiens, B.6
Wojtaszewski, J.F.P.7
Pilegaard, H.8
-
32
-
-
38949196761
-
PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle
-
Leick L, Wojtaszewski JFP, Johansen ST, Kiilerich K, Comes G, Hellsten Y, Hidalgo J & Pilegaard H (2008). PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle. Am J Physiol Endocrinol Metab 294, E463-E474.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Leick, L.1
Wojtaszewski, J.F.P.2
Johansen, S.T.3
Kiilerich, K.4
Comes, G.5
Hellsten, Y.6
Hidalgo, J.7
Pilegaard, H.8
-
33
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
-
amp;
-
Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY, Mootha VK, Jäger S, Vianna CR, Reznick RM, Cui L, Manieri M, Donovan MX, Wu Z, Cooper MP, Fan MC, Rohas LM, Zavacki AM, Cinti S, Shulman GI, Lowell BB, Krainc D & Spiegelman BM. (2004). Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell 119, 121-135.
-
(2004)
Cell
, vol.119
, pp. 121-135
-
-
Lin, J.1
Wu, P.H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
Zhang, C.Y.6
Mootha, V.K.7
Jäger, S.8
Vianna, C.R.9
Reznick, R.M.10
Cui, L.11
Manieri, M.12
Donovan, M.X.13
Wu, Z.14
Cooper, M.P.15
Fan, M.C.16
Rohas, L.M.17
Zavacki, A.M.18
Cinti, S.19
Shulman, G.I.20
Lowell, B.B.21
Krainc, D.22
Spiegelman, B.M.23
more..
-
34
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin S-J, Defossez PA & Guarente L (2000). Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289, 2126-2128.
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.-J.1
Defossez, P.A.2
Guarente, L.3
-
35
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
-
Lin S-J, Kaeberlein M, Andalis AA, Sturtz LA, Defossez P-A, Culotta VC, Fink GR & Guarente L (2002). Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418, 344-348.
-
(2002)
Nature
, vol.418
, pp. 344-348
-
-
Lin, S.-J.1
Kaeberlein, M.2
Andalis, A.A.3
Sturtz, L.A.4
Defossez, P.-A.5
Culotta, V.C.6
Fink, G.R.7
Guarente, L.8
-
36
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L & Gu W (2001). Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107, 137-148.
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
37
-
-
0037381848
-
Exercise increases nuclear AMPK alpha2 in human skeletal muscle
-
McGee SL, Howlett KF, Starkie RL, Cameron-Smith D, Kemp BE & Hargreaves M (2003). Exercise increases nuclear AMPK alpha2 in human skeletal muscle. Diabetes 52, 926-928.
-
(2003)
Diabetes
, vol.52
, pp. 926-928
-
-
McGee, S.L.1
Howlett, K.F.2
Starkie, R.L.3
Cameron-Smith, D.4
Kemp, B.E.5
Hargreaves, M.6
-
38
-
-
0035947235
-
A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle
-
Mu J, Brozinick JT Jr, Valladares O, Bucan M & Birnbaum MJ (2001). A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle. Mol Cell 7, 1085-1094.
-
(2001)
Mol Cell
, vol.7
, pp. 1085-1094
-
-
Mu, J.1
Brozinick Jr., J.T.2
Valladares, O.3
Bucan, M.4
Birnbaum, M.J.5
-
39
-
-
0036299982
-
Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes
-
Musi N, Hirshman MF, Nygren J, Svanfeldt M, Bavenholm P, Rooyackers O, Zhou G, Williamson JM, Ljunqvist O, Efendic S, Moller DE, Thorell A & Goodyear LJ (2002). Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes 51, 2074-2081.
-
(2002)
Diabetes
, vol.51
, pp. 2074-2081
-
-
Musi, N.1
Hirshman, M.F.2
Nygren, J.3
Svanfeldt, M.4
Bavenholm, P.5
Rooyackers, O.6
Zhou, G.7
Williamson, J.M.8
Ljunqvist, O.9
Efendic, S.10
Moller, D.E.11
Thorell, A.12
Goodyear, L.J.13
-
40
-
-
18144411313
-
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}
-
Nemoto S, Fergusson MM & Finkel T (2005). SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}. J Biol Chem 280, 16456-16460.
-
(2005)
J Biol Chem
, vol.280
, pp. 16456-16460
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
41
-
-
80052193535
-
Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) deacetylation following endurance exercise
-
Philp A, Chen A, Lan D, Meyer GA, Murphy AN, Knapp AE, Olfert IM, McCurdy CE, Marcotte GR, Hogan MC, Baar K & Schenk S (2011). Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) deacetylation following endurance exercise. J Biol Chem 286, 30561-30570.
-
(2011)
J Biol Chem
, vol.286
, pp. 30561-30570
-
-
Philp, A.1
Chen, A.2
Lan, D.3
Meyer, G.A.4
Murphy, A.N.5
Knapp, A.E.6
Olfert, I.M.7
McCurdy, C.E.8
Marcotte, G.R.9
Hogan, M.C.10
Baar, K.11
Schenk, S.12
-
42
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M & Spiegelman BM (1998). A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92, 829-839.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
43
-
-
0017275889
-
Magnitude and significance of NAD turnover in human cell line D98/AH2
-
Rechsteiner M, Hillyard D & Olivera BM (1976). Magnitude and significance of NAD turnover in human cell line D98/AH2. Nature 259, 695-696.
-
(1976)
Nature
, vol.259
, pp. 695-696
-
-
Rechsteiner, M.1
Hillyard, D.2
Olivera, B.M.3
-
44
-
-
10944270187
-
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
-
Revollo JR, Grimm AA & Imai S (2004). The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. J Biol Chem 279, 50754-50763.
-
(2004)
J Biol Chem
, vol.279
, pp. 50754-50763
-
-
Revollo, J.R.1
Grimm, A.A.2
Imai, S.3
-
45
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM & Puigserver P (2005). Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434, 113-118.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
46
-
-
63849188637
-
(2+)-calmodulin-eEF2K-eEF2 signalling cascade, but not AMPK, contributes to the suppression of skeletal muscle protein synthesis during contractions
-
(2+)-calmodulin-eEF2K-eEF2 signalling cascade, but not AMPK, contributes to the suppression of skeletal muscle protein synthesis during contractions. J Physiol 587, 1547-1563.
-
(2009)
J Physiol
, vol.587
, pp. 1547-1563
-
-
Rose, A.J.1
Alsted, T.J.2
Jensen, T.E.3
Kobberø, J.B.4
Maarbjerg, S.J.5
Jensen, J.6
Richter, E.A.7
-
47
-
-
0020469121
-
Metabolism of 5-amino-4-imidazolecarboxamide riboside in cardiac and skeletal muscle. Effects on purine nucleotide synthesis
-
Sabina RL, Kernstine KH, Boyd RL, Holmes EW & Swain JL (1982). Metabolism of 5-amino-4-imidazolecarboxamide riboside in cardiac and skeletal muscle. Effects on purine nucleotide synthesis. J Biol Chem 257, 10178-10183.
-
(1982)
J Biol Chem
, vol.257
, pp. 10178-10183
-
-
Sabina, R.L.1
Kernstine, K.H.2
Boyd, R.L.3
Holmes, E.W.4
Swain, J.L.5
-
48
-
-
70349921265
-
A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle
-
Treebak JT, Birk JB, Hansen BF, Olsen GS & Wojtaszewski JFP (2009). A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle. Am J Physiol Cell Physiol 297, C1041-C1052.
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Treebak, J.T.1
Birk, J.B.2
Hansen, B.F.3
Olsen, G.S.4
Wojtaszewski, J.F.P.5
-
49
-
-
84862001123
-
Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells
-
Turban S, Stretton C, Drouin O, Green CJ, Watson ML, Gray A, Ross F, Lantier L, Viollet B, Hardie DG, Marette A & Hundal HS (2012). Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells. J Biol Chem 287, 20088-20099.
-
(2012)
J Biol Chem
, vol.287
, pp. 20088-20099
-
-
Turban, S.1
Stretton, C.2
Drouin, O.3
Green, C.J.4
Watson, M.L.5
Gray, A.6
Ross, F.7
Lantier, L.8
Viollet, B.9
Hardie, D.G.10
Marette, A.11
Hundal, H.S.12
-
50
-
-
0037251455
-
The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity
-
Viollet B, Andreelli F, Jørgensen SB, Perrin C, Geloen A, Flamez D, Mu J, Lenzner C, Baud O, Bennoun M, Gomas E, Nicolas G, Wojtaszewski JF, Kahn A, Carling D, Schuit FC, Birnbaum MJ, Richter EA, Burcelin R & Vaulont S (2003). The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity. J Clin Invest 111, 91-98.
-
(2003)
J Clin Invest
, vol.111
, pp. 91-98
-
-
Viollet, B.1
Andreelli, F.2
Jørgensen, S.B.3
Perrin, C.4
Geloen, A.5
Flamez, D.6
Mu, J.7
Lenzner, C.8
Baud, O.9
Bennoun, M.10
Gomas, E.11
Nicolas, G.12
Wojtaszewski, J.F.13
Kahn, A.14
Carling, D.15
Schuit, F.C.16
Birnbaum, M.J.17
Richter, E.A.18
Burcelin, R.19
Vaulont, S.20
more..
-
51
-
-
84860561281
-
Loss of AMP-activated protein kinase-α2 impairs the insulin-sensitizing effect of calorie restriction in skeletal muscle
-
Wang P, Zhang R-Y, Song J, Guan Y-F, Xu T-Y, Du H, Viollet B & Miao C-Y (2012). Loss of AMP-activated protein kinase-α2 impairs the insulin-sensitizing effect of calorie restriction in skeletal muscle. Diabetes 61, 1051-1061.
-
(2012)
Diabetes
, vol.61
, pp. 1051-1061
-
-
Wang, P.1
Zhang, R.-Y.2
Song, J.3
Guan, Y.-F.4
Xu, T.-Y.5
Du, H.6
Viollet, B.7
Miao, C.-Y.8
-
52
-
-
17844400342
-
5′AMP activated protein kinase expression in human skeletal muscle: effects of strength training and type 2 diabetes
-
Wojtaszewski JFP, Birk JB, Frøsig C, Holten M, Pilegaard H & Dela F (2005). 5′AMP activated protein kinase expression in human skeletal muscle: effects of strength training and type 2 diabetes. J Physiol 564, 563-573.
-
(2005)
J Physiol
, vol.564
, pp. 563-573
-
-
Wojtaszewski, J.F.P.1
Birk, J.B.2
Frøsig, C.3
Holten, M.4
Pilegaard, H.5
Dela, F.6
-
53
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ & Moller DE (2001). Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108, 1167-1174.
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
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