Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation

Journal of Molecular and Cellular Cardiology

Volumn 57, Issue 1, 2013, Pages 82-95

  Bai, Yang ^a,b,c   Cui, Wenpeng ^b,d   Xin, Ying ^b,e   Miao, Xiao ^b,d   Barati, Michelle T ^b   Zhang, Chi ^b   Chen, Qiang ^a,b   Tan, Yi ^b   Cui, Taixing ^f   Zheng, Yang ^a   Cai, Lu ^a,b  

^a JILIN UNIVERSITY   (China)

^b University of Louisville School of Medicine   (United States)

^c Jilin Province People's Hospital   (China)

^d THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^e Basic Medical College   (China)

^f UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiac dysfunction; Cardiomyopathy; Nrf2; Oxidative damage; Sulforaphane

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; ATRIAL NATRIURETIC FACTOR; COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; GLUCOSE; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DIABETIC HYPERTENSION; GENE; GENE EXPRESSION REGULATION; GENE SILENCING; HEART MUSCLE FIBROSIS; HISTOPATHOLOGY; HYPERGLYCEMIA; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MOUSE; NONHUMAN; NRF2 GENE; OXIDATIVE STRESS; PREVENTIVE MEDICINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

ANIMALS; CATALASE; CELL LINE; CONNECTIVE TISSUE GROWTH FACTOR; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DRUG EVALUATION, PRECLINICAL; FIBROSIS; HEME OXYGENASE-1; HYPERTROPHY, LEFT VENTRICULAR; LIPID PEROXIDATION; MALE; MEMBRANE PROTEINS; MICE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; SERPIN E2; SUPEROXIDE DISMUTASE; THIOCYANATES; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

MUS;

EID: 84873737258     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.01.008     Document Type: Article

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