Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders

Epigenomics

Volumn 7, Issue 3, 2015, Pages 503-518

  Vallianatos, Christina N ^a,b   Iwase, Shigeki ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

autism spectrum disorders; brain development; chromatin; epigenetics; gene regulation; H3K4 methylation; histone methylation; intellectual disability; schizophrenia

Indexed keywords

HISTONE DEMETHYLASE; HISTONE H3; HISTONE H3K4; HISTONE LYSINE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; LONG UNTRANSLATED RNA; PROTEIN; PROTEIN KDM1A; PROTEIN KDM5C; PROTEIN KMT2A; PROTEIN KMT2D; PROTEIN KMT2F; PROTEIN PHF21A; PROTEIN PHF8; RETINOBLASTOMA BINDING PROTEIN 2; SYNAPSIN I; UNCLASSIFIED DRUG; HISTONE;

AUTISM; BRAIN DEVELOPMENT; BRAIN FUNCTION; CHROMATIN; COGNITIVE DEFECT; CRANIOFACIAL DEVELOPMENT; DEVELOPMENTAL DISORDER; ENZYME ACTIVITY; GAIN OF FUNCTION MUTATION; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENETIC SUSCEPTIBILITY; GENETIC TRANSCRIPTION; HISTONE METHYLATION; HUMAN; KABUKI MAKEUP SYNDROME; LOSS OF FUNCTION MUTATION; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NEUROLOGIC DISEASE; NEXT GENERATION SEQUENCING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; REVIEW; SCHIZOPHRENIA; TRANSCRIPTION INITIATION SITE; GENETICS; INTELLECTUAL IMPAIRMENT; METABOLISM; METHYLATION; MUTATION;

CHILD DEVELOPMENT DISORDERS, PERVASIVE; DEVELOPMENTAL DISABILITIES; HISTONE DEMETHYLASES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; INTELLECTUAL DISABILITY; METHYLATION; MUTATION; SCHIZOPHRENIA;

EID: 84931468275     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.15.1     Document Type: Review

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