-
1
-
-
34548150187
-
The role of nuclear architecture in genomic instability and ageing
-
Oberdoerffer P, Sinclair DA (2007) The role of nuclear architecture in genomic instability and ageing. Nat Rev Mol Cell Biol 8(9):692-702.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.9
, pp. 692-702
-
-
Oberdoerffer, P.1
Sinclair, D.A.2
-
2
-
-
84865364870
-
Playing the end game: DNA double-strand break repair pathway choice
-
Chapman JR, Taylor MR, Boulton SJ (2012) Playing the end game: DNA double-strand break repair pathway choice. Mol Cell 47(4):497-510.
-
(2012)
Mol Cell
, vol.47
, Issue.4
, pp. 497-510
-
-
Chapman, J.R.1
Taylor, M.R.2
Boulton, S.J.3
-
3
-
-
84861875303
-
Chromatin dynamics in DNA double-strand break repair
-
Shi L, Oberdoerffer P (2012) Chromatin dynamics in DNA double-strand break repair. Biochim Biophys Acta 1819(7):811-819.
-
(2012)
Biochim Biophys Acta
, vol.1819
, Issue.7
, pp. 811-819
-
-
Shi, L.1
Oberdoerffer, P.2
-
4
-
-
57149136324
-
GammaH2AX and cancer
-
Bonner WM, et al. (2008) GammaH2AX and cancer. Nat Rev Cancer 8(12):957-967.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.12
, pp. 957-967
-
-
Bonner, W.M.1
-
5
-
-
75949124023
-
Assembly of checkpoint and repair machineries at DNA damage sites
-
Huen MS, Chen J (2010) Assembly of checkpoint and repair machineries at DNA damage sites. Trends Biochem Sci 35(2):101-108.
-
(2010)
Trends Biochem Sci
, vol.35
, Issue.2
, pp. 101-108
-
-
Huen, M.S.1
Chen, J.2
-
6
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications
-
Polo SE, Jackson SP (2011) Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications. Genes Dev 25(5):409-433.
-
(2011)
Genes Dev
, vol.25
, Issue.5
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
7
-
-
78651386197
-
ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks
-
Zha S, et al. (2011) ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks. Nature 469(7329):250-254.
-
(2011)
Nature
, vol.469
, Issue.7329
, pp. 250-254
-
-
Zha, S.1
-
8
-
-
62849083222
-
The emerging role of nuclear architecture in DNA repair and genome maintenance
-
Misteli T, Soutoglou E (2009) The emerging role of nuclear architecture in DNA repair and genome maintenance. Nat Rev Mol Cell Biol 10(4):243-254.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.4
, pp. 243-254
-
-
Misteli, T.1
Soutoglou, E.2
-
9
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
-
Bunting SF, et al. (2010) 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 141(2):243-254.
-
(2010)
Cell
, vol.141
, Issue.2
, pp. 243-254
-
-
Bunting, S.F.1
-
10
-
-
11144357255
-
Cellular machineries for chromosomal DNA repair
-
Peterson CL, Côté J (2004) Cellular machineries for chromosomal DNA repair. Genes Dev 18(6):602-616.
-
(2004)
Genes Dev
, vol.18
, Issue.6
, pp. 602-616
-
-
Peterson, C.L.1
Côté, J.2
-
11
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand N, et al. (2007) RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 131(5):887-900.
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 887-900
-
-
Mailand, N.1
-
12
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil C, et al. (2009) RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 136(3):435-446.
-
(2009)
Cell
, vol.136
, Issue.3
, pp. 435-446
-
-
Doil, C.1
-
13
-
-
21244456772
-
Complicated tails: Histone modifications and the DNA damage response
-
Vidanes GM, Bonilla CY, Toczyski DP (2005) Complicated tails: Histone modifications and the DNA damage response. Cell 121(7):973-976.
-
(2005)
Cell
, vol.121
, Issue.7
, pp. 973-976
-
-
Vidanes, G.M.1
Bonilla, C.Y.2
Toczyski, D.P.3
-
14
-
-
33847076248
-
Chromatin challenges during DNA replication and repair
-
Groth A, Rocha W, Verreault A, Almouzni G (2007) Chromatin challenges during DNA replication and repair. Cell 128(4):721-733.
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 721-733
-
-
Groth, A.1
Rocha, W.2
Verreault, A.3
Almouzni, G.4
-
15
-
-
77956341931
-
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining
-
Miller KM, et al. (2010) Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. Nat Struct Mol Biol 17(9): 1144-1151.
-
(2010)
Nat Struct Mol Biol
, vol.17
, Issue.9
, pp. 1144-1151
-
-
Miller, K.M.1
-
16
-
-
79952270884
-
HDACs link the DNA damage response, processing of double-strand breaks and autophagy
-
Robert T, et al. (2011) HDACs link the DNA damage response, processing of double-strand breaks and autophagy. Nature 471(7336):74-79.
-
(2011)
Nature
, vol.471
, Issue.7336
, pp. 74-79
-
-
Robert, T.1
-
17
-
-
79952256559
-
Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining
-
Fnu S, et al. (2011) Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining. Proc Natl Acad Sci USA 108(2):540-545.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.2
, pp. 540-545
-
-
Fnu, S.1
-
18
-
-
79551665780
-
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
-
Pei H, et al. (2011) MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature 470(7332):124-128.
-
(2011)
Nature
, vol.470
, Issue.7332
, pp. 124-128
-
-
Pei, H.1
-
19
-
-
33947244845
-
PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation
-
Yamane K, et al. (2007) PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. Mol Cell 25(6):801-812.
-
(2007)
Mol Cell
, vol.25
, Issue.6
, pp. 801-812
-
-
Yamane, K.1
-
20
-
-
80155131102
-
Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14
-
Li Q, et al. (2011) Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14. Cancer Res 71(21):6899-6908.
-
(2011)
Cancer Res
, vol.71
, Issue.21
, pp. 6899-6908
-
-
Li, Q.1
-
21
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer P, et al. (2008) SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 135(5):907-918.
-
(2008)
Cell
, vol.135
, Issue.5
, pp. 907-918
-
-
Oberdoerffer, P.1
-
22
-
-
66049150672
-
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
-
McCord RA, et al. (2009) SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging (Albany, NY Online) 1(1):109-121.
-
(2009)
Aging (Albany, NY Online)
, vol.1
, Issue.1
, pp. 109-121
-
-
McCord, R.A.1
-
23
-
-
0033569684
-
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
-
Pierce AJ, Johnson RD, Thompson LH, Jasin M (1999) XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev 13(20):2633-2638.
-
(1999)
Genes Dev
, vol.13
, Issue.20
, pp. 2633-2638
-
-
Pierce, A.J.1
Johnson, R.D.2
Thompson, L.H.3
Jasin, M.4
-
24
-
-
30344444484
-
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
-
Murr R, et al. (2006) Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks. Nat Cell Biol 8(1):91-99.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.1
, pp. 91-99
-
-
Murr, R.1
-
25
-
-
77951498531
-
High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome
-
Iacovoni JS, et al. (2010) High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome. EMBO J 29(8):1446-1457.
-
(2010)
EMBO J
, vol.29
, Issue.8
, pp. 1446-1457
-
-
Iacovoni, J.S.1
-
26
-
-
77954274504
-
The PARP side of the nucleus: Molecular actions, physiological outcomes, and clinical targets
-
Krishnakumar R, Kraus WL (2010) The PARP side of the nucleus: Molecular actions, physiological outcomes, and clinical targets. Mol Cell 39(1):8-24.
-
(2010)
Mol Cell
, vol.39
, Issue.1
, pp. 8-24
-
-
Krishnakumar, R.1
Kraus, W.L.2
-
27
-
-
79959363092
-
SIRT6 promotes DNA repair under stress by activating PARP1
-
Mao Z, et al. (2011) SIRT6 promotes DNA repair under stress by activating PARP1. Science 332(6036):1443-1446.
-
(2011)
Science
, vol.332
, Issue.6036
, pp. 1443-1446
-
-
Mao, Z.1
-
28
-
-
77956526559
-
PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway
-
Krishnakumar R, Kraus WL (2010) PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway. Mol Cell 39(5):736-749.
-
(2010)
Mol Cell
, vol.39
, Issue.5
, pp. 736-749
-
-
Krishnakumar, R.1
Kraus, W.L.2
-
29
-
-
69949133036
-
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation
-
Timinszky G, et al. (2009) A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat Struct Mol Biol 16(9):923-929.
-
(2009)
Nat Struct Mol Biol
, vol.16
, Issue.9
, pp. 923-929
-
-
Timinszky, G.1
-
30
-
-
78649349810
-
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
-
Chou DM, et al. (2010) A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proc Natl Acad Sci USA 107(43):18475-18480.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.43
, pp. 18475-18480
-
-
Chou, D.M.1
-
31
-
-
77956870690
-
Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4
-
Polo SE, Kaidi A, Baskcomb L, Galanty Y, Jackson SP (2010) Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4. EMBO J 29(18):3130-3139.
-
(2010)
EMBO J
, vol.29
, Issue.18
, pp. 3130-3139
-
-
Polo, S.E.1
Kaidi, A.2
Baskcomb, L.3
Galanty, Y.4
Jackson, S.P.5
-
32
-
-
77955452081
-
Multiple facets of the unique histone variant macroH2A: From genomics to cell biology
-
Gamble MJ, Kraus WL (2010) Multiple facets of the unique histone variant macroH2A: From genomics to cell biology. Cell Cycle 9(13):2568-2574.
-
(2010)
Cell Cycle
, vol.9
, Issue.13
, pp. 2568-2574
-
-
Gamble, M.J.1
Kraus, W.L.2
-
33
-
-
33847613217
-
Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins
-
Seward DJ, et al. (2007) Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins. Nat Struct Mol Biol 14(3):240-242.
-
(2007)
Nat Struct Mol Biol
, vol.14
, Issue.3
, pp. 240-242
-
-
Seward, D.J.1
-
34
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiq-uitylation and checkpoint protein assembly
-
Huen MS, et al. (2007) RNF8 transduces the DNA-damage signal via histone ubiq-uitylation and checkpoint protein assembly. Cell 131(5):901-914.
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 901-914
-
-
Huen, M.S.1
-
35
-
-
33646438365
-
Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
-
Huang Y, Fang J, Bedford MT, Zhang Y, Xu RM (2006) Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A. Science 312(5774): 748-751.
-
(2006)
Science
, vol.312
, Issue.5774
, pp. 748-751
-
-
Huang, Y.1
Fang, J.2
Bedford, M.T.3
Zhang, Y.4
Xu, R.M.5
|