H3K4 mono- And di-methyltransferase MLL4 is required for enhancer activation during cell differentiation

eLife

Volumn 2013, Issue 2, 2013, Pages

  Lee, Ji Eun ^a   Wang, Chaochen ^a   Xu, Shiliyang ^a,b   Cho, Young Wook ^a,c   Wang, Lifeng ^a   Feng, Xuesong ^d   Baldridge, Anne ^a   Sartorelli, Vittorio ^d   Zhuang, Lenan ^a   Peng, Weiqun ^b   Ge, Kai ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b GEORGE WASHINGTON UNIVERSITY   (United States)

^c Korea Basic Science Institute (KBSI)   (South Korea)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLTRANSFERASE; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE ALPHA; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; MEDIATOR COMPLEX; MLL3 PROTEIN, MOUSE; MLL4 PROTEIN, HUMAN; MLL4 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ADIPOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; GENE EXPRESSION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; LOSS OF FUNCTION MUTATION; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; 3T3 CELL LINE; ADIPOCYTE; ANIMAL; BINDING SITE; BIOLOGY; CELL LINEAGE; DEFICIENCY; ENHANCER REGION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; GENOMICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; METHYLATION; MUSCLE CELL; PROCEDURES; PROMOTER REGION; TIME;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; BINDING SITES; CELL LINEAGE; COMPUTATIONAL BIOLOGY; DNA POLYMERASE II; DNA-BINDING PROTEINS; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOMICS; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; MEDIATOR COMPLEX; METHYLATION; MICE; MICE, KNOCKOUT; MUSCLE CELLS; MUSCLE DEVELOPMENT; PROMOTER REGIONS, GENETIC; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84891541640     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.01503     Document Type: Article

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