메뉴 건너뛰기




Volumn 47, Issue 1, 2015, Pages 231-243

Fbxw7 regulates hepatocellular carcinoma migration and invasion via Notch 1 signaling pathway

Author keywords

Fbxw7; Hepatocellular carcinoma; Invasion; Migration; Notchl

Indexed keywords

F BOX AND WD REPEAT DOMAIN CONTAINING 7 PROTEIN; GELATINASE A; GELATINASE B; MESSENGER RNA; NOTCH1 RECEPTOR; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; UROKINASE; CELL CYCLE PROTEIN; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; NOTCH1 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

EID: 84931083259     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2015.2981     Document Type: Article
Times cited : (30)

References (68)
  • 1
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: From genes to environment
    • Farazi PA and DePinho RA: Hepatocellular carcinoma pathogenesis: From genes to environment. Nat Rev Cancer 6: 674-687, 2006.
    • (2006) Nat Rev Cancer , vol.6 , pp. 674-687
    • Farazi, P.A.1    Depinho, R.A.2
  • 2
    • 70349575079 scopus 로고    scopus 로고
    • Lymphotoxins: New targets for hepatocellular carcinoma
    • Villanueva A, Savic R and Llovet JM: Lymphotoxins: New targets for hepatocellular carcinoma. Cancer Cell 16: 272-273, 2009.
    • (2009) Cancer Cell , vol.16 , pp. 272-273
    • Villanueva, A.1    Savic, R.2    Llovet, J.M.3
  • 4
    • 38549086019 scopus 로고    scopus 로고
    • FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
    • Welcker M and Clurman BE: FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation. Nat Rev Cancer 8: 83-93, 2008.
    • (2008) Nat Rev Cancer , vol.8 , pp. 83-93
    • Welcker, M.1    Clurman, B.E.2
  • 7
    • 2942650133 scopus 로고    scopus 로고
    • The fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-myc protein degradation
    • Welcker M, Orian A, Jin J., Grim JE, Harper JW, Eisenman RN and Clurman BE: The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proc Natl Acad Sci USA 101: 9085-9090, 2004
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9085-9090
    • Welcker, M.1    Orian, A.2    Jin, J.3    Grim, J.E.4    Harper, J.W.5    Eisenman, R.N.6    Clurman, B.E.7
  • 9
    • 84865183905 scopus 로고    scopus 로고
    • Evaluation of fbxw7 expression and its correlation with expression of SREBP-1 in a mouse model of NAFLD
    • Tu K, Zheng X, Yin G., Zan X, Yao Y and Liu Q: Evaluation of Fbxw7 expression and its correlation with expression of SREBP-1 in a mouse model of NAFLD. Mol Med Rep 6: 525-530, 2012.
    • (2012) Mol Med Rep , vol.6 , pp. 525-530
    • Tu, K.1    Zheng, X.2    Yin, G.3    Zan, X.4    Yao, Y.5    Liu, Q.6
  • 10
    • 1342275412 scopus 로고    scopus 로고
    • The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling
    • Nateri AS, Riera-Sans L, Da Costa C and Behrens A: The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling. Science 303: 1374-1378, 2004
    • (2004) Science , vol.303 , pp. 1374-1378
    • Nateri, A.S.1    Riera-Sans, L.2    Da Costa, C.3    Behrens, A.4
  • 11
    • 51749095471 scopus 로고    scopus 로고
    • FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression
    • Mao JH, Kim IJ, Wu D, Climent J., Kang HC, Del Rosario R and Balmain A: FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression. Science 321: 1499-1502, 2008.
    • (2008) Science , vol.321 , pp. 1499-1502
    • Mao, J.H.1    Kim, I.J.2    Wu, D.3    Climent, J.4    Kang, H.C.5    Del Rosario, R.6    Balmain, A.7
  • 13
    • 85028121020 scopus 로고    scopus 로고
    • Role of the ubiquitin ligase fbw7 in cancer progression
    • Cheng Y and Li G: Role of the ubiquitin ligase Fbw7 in cancer progression. Cancer Metastasis Rev 31: 75-87, 2012.
    • (2012) Cancer Metastasis Rev , vol.31 , pp. 75-87
    • Cheng, Y.1    Li, G.2
  • 18
    • 29244460649 scopus 로고    scopus 로고
    • CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability
    • Kemp Z, Rowan A, Chambers W., Wortham N, Haiford S, Sieber O., Mortensen N, von Herbay A, Günther T, Ilyas M, et al.: CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability. Cancer Res 65: 11361-11366, 2005
    • (2005) Cancer Res , vol.65 , pp. 11361-11366
    • Kemp, Z.1    Rowan, A.2    Chambers, W.3    Wortham, N.4    Haiford, S.5    Sieber, O.6    Mortensen, N.7    Von Herbay, A.8    Günther, T.9    Ilyas, M.10
  • 20
    • 32544446008 scopus 로고    scopus 로고
    • CDC4 gene expression as potential biomarker for targeted therapy in prostate cancer
    • Koh MS, Ittmann M, Kadmon D., Thompson TC and Leach FS: CDC4 gene expression as potential biomarker for targeted therapy in prostate cancer. Cancer Biol Ther 5: 78-83, 2006.
    • (2006) Cancer Biol Ther , vol.5 , pp. 78-83
    • Koh, M.S.1    Ittmann, M.2    Kadmon, D.3    Thompson, T.C.4    Leach, F.S.5
  • 21
    • 84862273253 scopus 로고    scopus 로고
    • MicroRNA-223 functions as an oncogene in human gastric cancer by targeting FBXW7/hCdc4
    • Li J, Guo Y, Liang X., Sun M, Wang G, De W and Wu W: MicroRNA-223 functions as an oncogene in human gastric cancer by targeting FBXW7/hCdc4 J Cancer Res Clin Oncol 138: 763-774, 2012.
    • (2012) J Cancer Res Clin Oncol , vol.138 , pp. 763-774
    • Li, J.1    Guo, Y.2    Liang, X.3    Sun, M.4    Wang, G.5    De, W.6    Wu, W.7
  • 22
    • 84879420289 scopus 로고    scopus 로고
    • Prognostic significance of fbw7 in human melanoma and its role in cell migration
    • Cheng Y, Chen G, Martinka M., Ho V and Li G: Prognostic significance of Fbw7 in human melanoma and its role in cell migration. J Invest Dermatol 133: 1794-1802, 2013.
    • (2013) J Invest Dermatol , vol.133 , pp. 1794-1802
    • Cheng, Y.1    Chen, G.2    Martinka, M.3    Ho, V.4    Li, G.5
  • 24
    • 84865124774 scopus 로고    scopus 로고
    • Evaluation of fbxw7 expression and its correlation with the expression of c-myc, cyclin E and p53 in human hepatocellular carcinoma
    • Tu K, Zheng X, Zan X., Han S, Yao Y and Liu Q: Evaluation of Fbxw7 expression and its correlation with the expression of c-Myc, cyclin E and p53 in human hepatocellular carcinoma. Hepatol Res 42: 904-910, 2012.
    • (2012) Hepatol Res , vol.42 , pp. 904-910
    • Tu, K.1    Zheng, X.2    Zan, X.3    Han, S.4    Yao, Y.5    Liu, Q.6
  • 25
    • 33645049305 scopus 로고    scopus 로고
    • Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells
    • Wang Z, Banerjee S, Li Y., Rahman KM, Zhang Y and Sarkar FH: Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells. Cancer Res 66: 2778-2784, 2006.
    • (2006) Cancer Res , vol.66 , pp. 2778-2784
    • Wang, Z.1    Banerjee, S.2    Li, Y.3    Rahman, K.M.4    Zhang, Y.5    Sarkar, F.H.6
  • 26
    • 84862908627 scopus 로고    scopus 로고
    • Notchl signaling pathway participates in cancer invasion by regulating MMPs in lingual squamous cell carcinoma
    • Yu B, Wei J, Qian X., Lei D, Ma Q and Liu Y Notchl signaling pathway participates in cancer invasion by regulating MMPs in lingual squamous cell carcinoma. Oncol Rep 27: 547-552, 2012.
    • (2012) Oncol Rep , vol.27 , pp. 547-552
    • Yu, B.1    Wei, J.2    Qian, X.3    Lei, D.4    Ma, Q.5    Liu, Y.6
  • 27
    • 80053162689 scopus 로고    scopus 로고
    • Notchl is involved in migration and invasion of human Breast cancer cells
    • Wang J, Fu L, Gu F and Ma Y Notchl is involved in migration and invasion of human breast cancer cells. Oncol Rep 26: 1295-1303, 2011.
    • (2011) Oncol Rep , vol.26 , pp. 1295-1303
    • Wang, J.1    Fu, L.2    Gu, F.3    Ma, Y.4
  • 28
    • 84865332828 scopus 로고    scopus 로고
    • Downregulation of the notch signaling pathway inhibits hepatocellular carcinoma cell invasion by inactivation of matrix metalloproteinase-2 and -9 and vascular endothelial growth factor
    • Zhou L, Wang DS, Li Q.J., Sun W., Zhang Y and Dou KF: Downregulation of the Notch signaling pathway inhibits hepatocellular carcinoma cell invasion by inactivation of matrix metalloproteinase-2 and -9 and vascular endothelial growth factor. Oncol Rep 28: 874-882, 2012.
    • (2012) Oncol Rep , vol.28 , pp. 874-882
    • Zhou, L.1    Wang, D.S.2    Li, Q.J.3    Sun, W.4    Zhang, Y.5    Dou, K.F.6
  • 29
    • 84874571685 scopus 로고    scopus 로고
    • The significance of notchl compared with notch3 in high metastasis and poor overall survival in hepatocellular carcinoma
    • Zhou L, Zhang N, Song W., You N, Li Q, Sun W., Zhang Y, Wang D and Dou K: The significance of Notchl compared with Notch3 in high metastasis and poor overall survival in hepatocellular carcinoma. PLoS One 8: e57382, 2013.
    • (2013) PLoS One , vol.8
    • Zhou, L.1    Zhang, N.2    Song, W.3    You, N.4    Li, Q.5    Sun, W.6    Zhang, Y.7    Wang, D.8    Dou, K.9
  • 31
    • 0029804330 scopus 로고    scopus 로고
    • Immunohistochemical determination of oestrogen receptor: Comparison of different methods of assessment of staining and correlation with clinical outcome of Breast cancer patients
    • Barnes DM, Harris WH, Smith P, Millis RR and Rubens RD: Immunohistochemical determination of oestrogen receptor: Comparison of different methods of assessment of staining and correlation with clinical outcome of breast cancer patients. Br J Cancer 74: 1445-1451, 1996.
    • (1996) Br J Cancer , vol.74 , pp. 1445-1451
    • Barnes, D.M.1    Harris, W.H.2    Smith, P.3    Millis, R.R.4    Rubens, R.D.5
  • 32
    • 84872775840 scopus 로고    scopus 로고
    • Associations between high levels of notchl expression and high invasion and poor overall survival in hepatocellular carcinoma
    • Zhou L, Zhang N, Li Q.J., Sun W., Zhang Y, Wang DS and Dou KF: Associations between high levels of Notchl expression and high invasion and poor overall survival in hepatocellular carcinoma. Tumour Biol 34: 543-553, 2013.
    • (2013) Tumour Biol , vol.34 , pp. 543-553
    • Zhou, L.1    Zhang, N.2    Li, Q.J.3    Sun, W.4    Zhang, Y.5    Wang, D.S.6    Dou, K.F.7
  • 36
    • 84879448595 scopus 로고    scopus 로고
    • Expression of fbxw7 and its correlation with cell proliferation in human hepatocellular carcinoma
    • (In Chinese)
    • Zhou ZY, Tu KS, Zhang J, Zheng X., Gao J, Yao YM and Liu QG: Expression of Fbxw7 and its correlation with cell proliferation in human hepatocellular carcinoma. Xi Bao Yu Fen Zi Mian Yi Xue ZaZhi 28: 1303-1306, 2012 (In Chinese).
    • (2012) Xi Bao Yu Fen Zi Mian Yi Xue ZaZhi , vol.28 , pp. 1303-1306
    • Zhou, Z.Y.1    Tu, K.S.2    Zhang, J.3    Zheng, X.4    Gao, J.5    Yao, Y.M.6    Liu, Q.G.7
  • 38
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas S, Rand MD and Lake RJ: Notch signaling: Cell fate control and signal integration in development. Science 284: 770-776, 1999
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 40
    • 0034710595 scopus 로고    scopus 로고
    • Notch signaling: Fringe really is a glycosyltransferase
    • Blair SS: Notch signaling: Fringe really is a glycosyltransferase. Curr Biol 10: R608-R612, 2000.
    • (2000) Curr Biol , vol.10 , pp. R608-R612
    • Blair, S.S.1
  • 41
    • 26444480631 scopus 로고    scopus 로고
    • Mechanisms of tumor suppression by the SCF(Fbw7)
    • Minella AC and Clurman BE: Mechanisms of tumor suppression by the SCF(Fbw7). Cell Cycle 4: 1356-1359, 2005
    • (2005) Cell Cycle , vol.4 , pp. 1356-1359
    • Minella, A.C.1    Clurman, B.E.2
  • 42
    • 0037154292 scopus 로고    scopus 로고
    • Protein degradation: Four E3s for the notch pathway
    • Lai EC: Protein degradation: Four E3s for the notch pathway. Curr Biol 12: R74-R78, 2002.
    • (2002) Curr Biol , vol.12 , pp. R74-R78
    • Lai, E.C.1
  • 43
    • 0035929669 scopus 로고    scopus 로고
    • The notch intracellular domain is ubiquitinated and negatively regulated by the mammalian sel-10 homolog
    • Oberg C, Li J, Pauley A., Wolf E, Gurney M and Lendahl U: The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog. J Biol Chem 276: 35847-35853, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 35847-35853
    • Oberg, C.1    Li, J.2    Pauley, A.3    Wolf, E.4    Gurney, M.5    Lendahl, U.6
  • 48
    • 84907075560 scopus 로고    scopus 로고
    • NOTCHl signaling contributes to cell growth, anti-apoptosis and metastasis in salivary adenoid cystic carcinoma
    • Su BH, Qu J, Song M., Huang XY, Hu XM, Xie J, Zhao Y., Ding LC, She L, Chen J, et al.: NOTCHl signaling contributes to cell growth, anti-apoptosis and metastasis in salivary adenoid cystic carcinoma. Oncotarget 5: 6885-6895, 2014
    • (2014) Oncotarget , vol.5 , pp. 6885-6895
    • Su, B.H.1    Qu, J.2    Song, M.3    Huang, X.Y.4    Hu, X.M.5    Xie, J.6    Zhao, Y.7    Ding, L.C.8    She, L.9    Chen, J.10
  • 49
    • 24944506696 scopus 로고    scopus 로고
    • High-level coexpres-sion of JAG1 and NOTCHl is observed in human Breast cancer and is associated with poor overall survival
    • Reedijk M, Odorcic S, Chang L., Zhang H, Miller N, McCready D.R., Lockwood G and Egan SE: High-level coexpres-sion of JAG1 and NOTCHl is observed in human breast cancer and is associated with poor overall survival. Cancer Res 65: 8530-8537, 2005
    • (2005) Cancer Res , vol.65 , pp. 8530-8537
    • Reedijk, M.1    Odorcic, S.2    Chang, L.3    Zhang, H.4    Miller, N.5    McCready, D.R.6    Lockwood, G.7    Egan, S.E.8
  • 50
    • 77952096249 scopus 로고    scopus 로고
    • High level of notchl protein is associated with poor overall survival in colorectal cancer
    • Chu D, Li Y, Wang W., Zhao Q, Li J, Lu Y., Li M, Dong G, Zhang H, Xie H, et al.: High level of Notchl protein is associated with poor overall survival in colorectal cancer. Ann Surg Oncol 17: 1337-1342, 2010.
    • (2010) Ann Surg Oncol , vol.17 , pp. 1337-1342
    • Chu, D.1    Li, Y.2    Wang, W.3    Zhao, Q.4    Li, J.5    Lu, Y.6    Li, M.7    Dong, G.8    Zhang, H.9    Xie, H.10
  • 51
    • 0037509851 scopus 로고    scopus 로고
    • Matrix metalloproteinases in cancer
    • Itoh Y and Nagase H: Matrix metalloproteinases in cancer. Essays Biochem 38: 21-36, 2002.
    • (2002) Essays Biochem , vol.38 , pp. 21-36
    • Itoh, Y.1    Nagase, H.2
  • 52
    • 31344458952 scopus 로고    scopus 로고
    • Structure and function of matrix metalloproteinases and TIMPs
    • Nagase H, Visse R and Murphy G: Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res 69: 562-573, 2006.
    • (2006) Cardiovasc Res , vol.69 , pp. 562-573
    • Nagase, H.1    Visse, R.2    Murphy, G.3
  • 53
    • 0036581406 scopus 로고    scopus 로고
    • Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells
    • Kato Y, Yamashita T and Ishikawa M: Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells. Oncol Rep 9: 565-569, 2002.
    • (2002) Oncol Rep , vol.9 , pp. 565-569
    • Kato, Y.1    Yamashita, T.2    Ishikawa, M.3
  • 56
    • 13244291565 scopus 로고    scopus 로고
    • Expression and quantitative analysis of matrix metalloproteinase-2 and -9 in human gliomas
    • Komatsu K, Nakanishi Y, Nemoto N., Hori T, Sawada T and Kobayashi M: Expression and quantitative analysis of matrix metalloproteinase-2 and -9 in human gliomas. Brain Tumor Pathol 21: 105-112, 2004
    • (2004) Brain Tumor Pathol , vol.21 , pp. 105-112
    • Komatsu, K.1    Nakanishi, Y.2    Nemoto, N.3    Hori, T.4    Sawada, T.5    Kobayashi, M.6
  • 57
    • 67651071905 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and Breast cancer cell lines: New findings and review of the literature
    • Köhrmann A, Kammerer U, Kapp M., Dietl J and Anacker J: Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature. BMC Cancer 9: 188, 2009
    • (2009) BMC Cancer , vol.9 , pp. 188
    • Köhrmann, A.1    Kammerer, U.2    Kapp, M.3    Dietl, J.4    Anacker, J.5
  • 58
    • 0029294650 scopus 로고
    • The structure and function of the urokinase receptor, a membrane protein governing plasminogen activation on the cell surface
    • Behrendt N, Rønne E and Danø K: The structure and function of the urokinase receptor, a membrane protein governing plasminogen activation on the cell surface. Biol Chem Hoppe Seyler 376: 269-279, 1995
    • (1995) Biol Chem Hoppe Seyler , vol.376 , pp. 269-279
    • Behrendt, N.1    Rønne, E.2    Danø, K.3
  • 59
    • 15844408670 scopus 로고    scopus 로고
    • Proteolytic-antiproteolytic balance and its regulation in carcinogenesis
    • Skrzydlewska E, Sulkowska M, Koda M and Sulkowski S: Proteolytic-antiproteolytic balance and its regulation in carcinogenesis. World J Gastroenterol 11: 1251-1266, 2005
    • (2005) World J Gastroenterol , vol.11 , pp. 1251-1266
    • Skrzydlewska, E.1    Sulkowska, M.2    Koda, M.3    Sulkowski, S.4
  • 60
    • 79953163995 scopus 로고    scopus 로고
    • Proteolytic networks in cancer
    • Mason SD and Joyce JA: Proteolytic networks in cancer. Trends Cell Biol 21: 228-237, 2011.
    • (2011) Trends Cell Biol , vol.21 , pp. 228-237
    • Mason, S.D.1    Joyce, J.A.2
  • 61
    • 78651388566 scopus 로고    scopus 로고
    • Plasminogen activator uPA is a direct transcriptional target of the JAG1-notch receptor signaling pathway in Breast cancer
    • Shimizu M, Cohen B, Goldvasser P., Berman H, Virtanen C and Reedijk M: Plasminogen activator uPA is a direct transcriptional target of the JAG1-Notch receptor signaling pathway in breast cancer. Cancer Res 71: 277-286, 2011.
    • (2011) Cancer Res , vol.71 , pp. 277-286
    • Shimizu, M.1    Cohen, B.2    Goldvasser, P.3    Berman, H.4    Virtanen, C.5    Reedijk, M.6
  • 63
    • 0030723163 scopus 로고    scopus 로고
    • Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the rac and extracellular signal-regulated kinase pathways
    • Anand-Apte B, Zetter BR, Viswanathan A, Qiu R.G., Chen J., Ruggieri R and Symons M: Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways. J Biol Chem 272: 30688-30692, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 30688-30692
    • Anand-Apte, B.1    Zetter, B.R.2    Viswanathan, A.3    Qiu, R.G.4    Chen, J.5    Ruggieri, R.6    Symons, M.7
  • 65
    • 0033959101 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion
    • Webb DJ, Nguyen DH and Gonias SL: Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion. J Cell Sci 113: 123-134, 2000.
    • (2000) J Cell Sci , vol.113 , pp. 123-134
    • Webb, D.J.1    Nguyen, D.H.2    Gonias, S.L.3
  • 68
    • 0041363324 scopus 로고    scopus 로고
    • Essential role for ERK mitogen-activated protein kinase in matrix metalloproteinase-9 regulation in rat cortical astrocytes
    • Arai K, Lee SR and Lo EH: Essential role for ERK mitogen-activated protein kinase in matrix metalloproteinase-9 regulation in rat cortical astrocytes. Glia 43: 254-264, 2003.
    • (2003) Glia , vol.43 , pp. 254-264
    • Arai, K.1    Lee, S.R.2    Lo, E.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.