-
1
-
-
67650385302
-
-
American Cancer Society. Atlanta
-
American Cancer Society. Cancer facts and figures. Atlanta; 2009.
-
(2009)
Cancer Facts and Figures
-
-
-
2
-
-
38649095227
-
uPA and PAI-1 in breast cancer: Review of their clinical utility and current validation in the prospective NNBC-3 trial
-
Annecke K, Schmitt M, Euler U, Zerm M, Paepke D, Paepke S, et al. uPA and PAI-1 in breast cancer: review of their clinical utility and current validation in the prospective NNBC-3 trial. Adv Clin Chem 2008;45:31-45.
-
(2008)
Adv Clin Chem
, vol.45
, pp. 31-45
-
-
Annecke, K.1
Schmitt, M.2
Euler, U.3
Zerm, M.4
Paepke, D.5
Paepke, S.6
-
3
-
-
12144261490
-
Urokinase-type plasminogen activator and its inhibitor type 1 predict disease outcome and therapy response in primary breast cancer
-
Harbeck N, Kates RE, Schmitt M, Gauger K, Kiechle M, Janicke F, et al. Urokinase-type plasminogen activator and its inhibitor type 1 predict disease outcome and therapy response in primary breast cancer. Clin Breast Cancer 2004;5:348-52.
-
(2004)
Clin Breast Cancer
, vol.5
, pp. 348-352
-
-
Harbeck, N.1
Kates, R.E.2
Schmitt, M.3
Gauger, K.4
Kiechle, M.5
Janicke, F.6
-
5
-
-
4444293744
-
Notch signaling in mammary development and oncogenesis
-
Callahan R, Egan SE. Notch signaling in mammary development and oncogenesis. J Mammary Gland Biol Neoplasia 2004;9:145-63.
-
(2004)
J Mammary Gland Biol Neoplasia
, vol.9
, pp. 145-163
-
-
Callahan, R.1
Egan, S.E.2
-
6
-
-
0034642524
-
Identification of a novel NOTCH-4/INT-3 RNA species encoding an activated gene product in certain human tumor cell lines
-
Imatani A, Callahan R. Identification of a novel NOTCH-4/INT-3 RNA species encoding an activated gene product in certain human tumor cell lines. Oncogene 2000;19:223-31.
-
(2000)
Oncogene
, vol.19
, pp. 223-231
-
-
Imatani, A.1
Callahan, R.2
-
7
-
-
48549103124
-
Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches
-
Rizzo P, Miao H, D'Souza G, Osipo C, Song LL, Yun J, et al. Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Res 2008;68:5226-35.
-
(2008)
Cancer Res
, vol.68
, pp. 5226-5235
-
-
Rizzo, P.1
Miao, H.2
D'Souza, G.3
Osipo, C.4
Song, L.L.5
Yun, J.6
-
8
-
-
32944470488
-
Aberrant activation of notch signaling in human breast cancer
-
Stylianou S, Clarke RB, Brennan K. Aberrant activation of notch signaling in human breast cancer. Cancer Res 2006;66:1517-25.
-
(2006)
Cancer Res
, vol.66
, pp. 1517-1525
-
-
Stylianou, S.1
Clarke, R.B.2
Brennan, K.3
-
9
-
-
0036734148
-
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells
-
Weijzen S, Rizzo P, Braid M, Vaishnav R, Jonkheer SM, Zlobin A, et al. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat Med 2002;8:979-86.
-
(2002)
Nat Med
, vol.8
, pp. 979-986
-
-
Weijzen, S.1
Rizzo, P.2
Braid, M.3
Vaishnav, R.4
Jonkheer, S.M.5
Zlobin, A.6
-
10
-
-
7244250027
-
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
-
Pece S, Serresi M, Santolini E, Capra M, Hulleman E, Galimberti V, et al. Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J Cell Biol 2004;167:215-21.
-
(2004)
J Cell Biol
, vol.167
, pp. 215-221
-
-
Pece, S.1
Serresi, M.2
Santolini, E.3
Capra, M.4
Hulleman, E.5
Galimberti, V.6
-
11
-
-
34249098132
-
High-level JAG1 mRNA and protein predict poor outcome in breast cancer
-
Dickson BC, Mulligan AM, Zhang H, Lockwood G, O'Malley FP, Egan SE, et al. High-level JAG1 mRNA and protein predict poor outcome in breast cancer. Mod Pathol 2007;20:685-93.
-
(2007)
Mod Pathol
, vol.20
, pp. 685-693
-
-
Dickson, B.C.1
Mulligan, A.M.2
Zhang, H.3
Lockwood, G.4
O'Malley, F.P.5
Egan, S.E.6
-
12
-
-
24944506696
-
High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
-
Reedijk M, Odorcic S, Chang L, Zhang H, Miller N, McCready DR, et al. High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res 2005;65:8530-7.
-
(2005)
Cancer Res
, vol.65
, pp. 8530-8537
-
-
Reedijk, M.1
Odorcic, S.2
Chang, L.3
Zhang, H.4
Miller, N.5
McCready, D.R.6
-
13
-
-
51649090695
-
JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer
-
Reedijk M, Pinnaduwage D, Dickson BC, Mulligan AM, Zhang H, Bull SB, et al. JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer. Breast Cancer Res Treat 2008;111:439-48.
-
(2008)
Breast Cancer Res Treat
, vol.111
, pp. 439-448
-
-
Reedijk, M.1
Pinnaduwage, D.2
Dickson, B.C.3
Mulligan, A.M.4
Zhang, H.5
Bull, S.B.6
-
14
-
-
36248953716
-
Mammary stem cells and breast cancer-role of Notch signalling
-
Farnie G, Clarke RB. Mammary stem cells and breast cancer-role of Notch signalling. Stem Cell Rev 2007;3:169-75.
-
(2007)
Stem Cell Rev
, vol.3
, pp. 169-175
-
-
Farnie, G.1
Clarke, R.B.2
-
15
-
-
68049085887
-
In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models
-
Hoeflich KP, O'Brien C, Boyd Z, Cavet G, Guerrero S, Jung K, et al. In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models. Clin Cancer Res 2009;15:4649-64.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4649-4664
-
-
Hoeflich, K.P.1
O'Brien, C.2
Boyd, Z.3
Cavet, G.4
Guerrero, S.5
Jung, K.6
-
16
-
-
77951295615
-
Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines
-
Hollestelle A, Nagel JH, Smid M, Lam S, Elstrodt F, Wasielewski M, et al. Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines. Breast Cancer Res Treat 2010;121:53-64.
-
(2010)
Breast Cancer Res Treat
, vol.121
, pp. 53-64
-
-
Hollestelle, A.1
Nagel, J.H.2
Smid, M.3
Lam, S.4
Elstrodt, F.5
Wasielewski, M.6
-
17
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006;10:515-27.
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
Fevr, T.6
-
19
-
-
9444225935
-
Java Treeview-extensible visualization of microarray data
-
Saldanha AJ. Java Treeview-extensible visualization of microarray data. Bioinformatics 2004;20:3246-8.
-
(2004)
Bioinformatics
, vol.20
, pp. 3246-3248
-
-
Saldanha, A.J.1
-
20
-
-
0018854046
-
Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates
-
Heussen C, Dowdle EB. Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates. Anal Biochem 1980;102:196-202.
-
(1980)
Anal Biochem
, vol.102
, pp. 196-202
-
-
Heussen, C.1
Dowdle, E.B.2
-
21
-
-
55349117772
-
Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer
-
Park JT, Shih Ie M, Wang TL. Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer. Cancer Res 2008;68:8852-60.
-
(2008)
Cancer Res
, vol.68
, pp. 8852-8860
-
-
Park, J.T.1
Shih Ie, M.2
Wang, T.L.3
-
23
-
-
63849329353
-
A functional Notch-survivin gene signature in basal breast cancer
-
Lee CW, Simin K, Liu Q, Plescia J, Guha M, Khan A, et al. A functional Notch-survivin gene signature in basal breast cancer. Breast Cancer Res 2008;10:R97.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Lee, C.W.1
Simin, K.2
Liu, Q.3
Plescia, J.4
Guha, M.5
Khan, A.6
-
24
-
-
77955768470
-
Cyclin D1 is a direct target of JAG1-mediated Notch signaling in breast cancer
-
Cohen B, Shimizu M, Izrailit J, Ng NF, Buchman Y, Pan JG, et al. Cyclin D1 is a direct target of JAG1-mediated Notch signaling in breast cancer. Breast Cancer Res Treat 2010;123:113-24.
-
(2010)
Breast Cancer Res Treat
, vol.123
, pp. 113-124
-
-
Cohen, B.1
Shimizu, M.2
Izrailit, J.3
Ng, N.F.4
Buchman, Y.5
Pan, J.G.6
-
25
-
-
58149334773
-
A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
-
Farmer P, Bonnefoi H, Anderle P, Cameron D, Wirapati P, Becette V, et al. A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer. Nat Med 2009;15:68-74.
-
(2009)
Nat Med
, vol.15
, pp. 68-74
-
-
Farmer, P.1
Bonnefoi, H.2
Anderle, P.3
Cameron, D.4
Wirapati, P.5
Becette, V.6
-
26
-
-
39749176127
-
Predicting features of breast cancer with gene expression patterns
-
Lu X, Lu X, Wang ZC, Iglehart JD, Zhang X, Richardson AL. Predicting features of breast cancer with gene expression patterns. Breast Cancer Res Treat 2008;108:191-201.
-
(2008)
Breast Cancer Res Treat
, vol.108
, pp. 191-201
-
-
Lu, X.1
Lu, X.2
Wang, Z.C.3
Iglehart, J.D.4
Zhang, X.5
Richardson, A.L.6
-
27
-
-
0033198359
-
Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators
-
Nellesen DT, Lai EC, Posakony JW. Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators. Dev Biol 1999;213:33-53.
-
(1999)
Dev Biol
, vol.213
, pp. 33-53
-
-
Nellesen, D.T.1
Lai, E.C.2
Posakony, J.W.3
-
28
-
-
0029980867
-
T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells
-
Guan E, Wang J, Laborda J, Norcross M, Baeuerle PA, Hoffman T. T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells. J Exp Med 1996;183:2025-32.
-
(1996)
J Exp Med
, vol.183
, pp. 2025-2032
-
-
Guan, E.1
Wang, J.2
Laborda, J.3
Norcross, M.4
Baeuerle, P.A.5
Hoffman, T.6
-
29
-
-
0031594575
-
NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa
-
Oswald F, Liptay S, Adler G, Schmid RM. NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa. Mol Cell Biol 1998;18:2077-88.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2077-2088
-
-
Oswald, F.1
Liptay, S.2
Adler, G.3
Schmid, R.M.4
-
30
-
-
33645049305
-
Downregulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells
-
Wang Z, Banerjee S, Li Y, Rahman KM, Zhang Y, Sarkar FH. Downregulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells. Cancer Res 2006;66:2778-84.
-
(2006)
Cancer Res
, vol.66
, pp. 2778-2784
-
-
Wang, Z.1
Banerjee, S.2
Li, Y.3
Rahman, K.M.4
Zhang, Y.5
Sarkar, F.H.6
-
31
-
-
0026592340
-
A novel complex between the p65 subunit of NF-kappa B and c-Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene
-
Hansen SK, Nerlov C, Zabel U, Verde P, Johnsen M, Baeuerle PA, et al. A novel complex between the p65 subunit of NF-kappa B and c-Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene. Embo J 1992;11:205-13.
-
(1992)
Embo J
, vol.11
, pp. 205-213
-
-
Hansen, S.K.1
Nerlov, C.2
Zabel, U.3
Verde, P.4
Johnsen, M.5
Baeuerle, P.A.6
-
32
-
-
33745131039
-
Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice
-
Klinakis A, Szabolcs M, Politi K, Kiaris H, Artavanis-Tsakonas S, Efstratiadis A. Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice. Proc Natl Acad Sci USA 2006;103:9262-7.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9262-9267
-
-
Klinakis, A.1
Szabolcs, M.2
Politi, K.3
Kiaris, H.4
Artavanis-Tsakonas, S.5
Efstratiadis, A.6
-
33
-
-
36549010842
-
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
-
Leong KG, Niessen K, Kulic I, Raouf A, Eaves C, Pollet I, et al. Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med 2007;204:2935-48.
-
(2007)
J Exp Med
, vol.204
, pp. 2935-2948
-
-
Leong, K.G.1
Niessen, K.2
Kulic, I.3
Raouf, A.4
Eaves, C.5
Pollet, I.6
-
34
-
-
60749133185
-
The urokinase-system in tumor tissue stroma of the breast and breast cancer cell invasion
-
Hildenbrand R, Schaaf A. The urokinase-system in tumor tissue stroma of the breast and breast cancer cell invasion. Int J Oncol 2009;34:15-23.
-
(2009)
Int J Oncol
, vol.34
, pp. 15-23
-
-
Hildenbrand, R.1
Schaaf, A.2
-
35
-
-
59449107891
-
Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator
-
Bin Hafeez B, Adhami VM, Asim M, Siddiqui IA, Bhat KM, Zhong W, et al. Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator. Clin Cancer Res 2009;15:452-9.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 452-459
-
-
Bin Hafeez, B.1
Adhami, V.M.2
Asim, M.3
Siddiqui, I.A.4
Bhat, K.M.5
Zhong, W.6
-
36
-
-
77953920780
-
MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells
-
Pang RT, Leung CO, Ye TM, Liu W, Chiu PC, Lam KK, et al. MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells. Carcinogenesis 2010;31: 1037-44.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1037-1044
-
-
Pang, R.T.1
Leung, C.O.2
Ye, T.M.3
Liu, W.4
Chiu, P.C.5
Lam, K.K.6
-
37
-
-
0025879527
-
Essential AP-1 and PEA3 binding elements in the human urokinase enhancer display cell type-specific activity
-
Nerlov C, Rorth P, Blasi F, Johnsen M. Essential AP-1 and PEA3 binding elements in the human urokinase enhancer display cell type-specific activity. Oncogene 1991;6:1583-92.
-
(1991)
Oncogene
, vol.6
, pp. 1583-1592
-
-
Nerlov, C.1
Rorth, P.2
Blasi, F.3
Johnsen, M.4
-
38
-
-
42449125705
-
Glucocorticoid (GC)-mediated down-regulation of urokinase plasminogen activator expression via the serum and GC regulated kinase-1/forkhead box O3a pathway
-
Pew T, Zou M, Brickley DR, Conzen SD. Glucocorticoid (GC)-mediated down-regulation of urokinase plasminogen activator expression via the serum and GC regulated kinase-1/forkhead box O3a pathway. Endocrinology 2008;149:2637-45.
-
(2008)
Endocrinology
, vol.149
, pp. 2637-2645
-
-
Pew, T.1
Zou, M.2
Brickley, D.R.3
Conzen, S.D.4
-
39
-
-
16844386886
-
Plasminogen activation and cancer
-
Dano K, Behrendt N, Hoyer-Hansen G, Johnsen M, Lund LR, Ploug M, et al. Plasminogen activation and cancer. Thromb Haemost 2005;93:676-81.
-
(2005)
Thromb Haemost
, vol.93
, pp. 676-681
-
-
Dano, K.1
Behrendt, N.2
Hoyer-Hansen, G.3
Johnsen, M.4
Lund, L.R.5
Ploug, M.6
-
40
-
-
34548571130
-
Phase I pharmacokinetic (PK), and pharmacodynamic (PD) trial of the novel oral Notch inhibitor MK-0752 in patients (pts) with advanced breast cancer (BC) and other solid tumors
-
Krop IE, Kosh M, Fearen I, Savoie J, Dallob A, Matthews C, et al. Phase I pharmacokinetic (PK), and pharmacodynamic (PD) trial of the novel oral Notch inhibitor MK-0752 in patients (pts) with advanced breast cancer (BC) and other solid tumors. J Clin Oncol 2006;24:10574.
-
(2006)
J Clin Oncol
, vol.24
, pp. 10574
-
-
Krop, I.E.1
Kosh, M.2
Fearen, I.3
Savoie, J.4
Dallob, A.5
Matthews, C.6
-
42
-
-
33645234720
-
Gamma-secretase inhibitors for Alzheimer's disease: Balancing efficacy and toxicity
-
Barten DM, Meredith JE Jr, Zaczek R, Houston JG, Albright CF. Gamma-secretase inhibitors for Alzheimer's disease: balancing efficacy and toxicity. Drugs R D 2006;7:87-97.
-
(2006)
Drugs R D
, vol.7
, pp. 87-97
-
-
Barten, D.M.1
Meredith Jr., J.E.2
Zaczek, R.3
Houston, J.G.4
Albright, C.F.5
|