CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability

Cancer Research

Volumn 65, Issue 24, 2005, Pages 11361-11366

  Kemp, Zoe ^a   Rowan, Andrew ^a   Chambers, William ^a,b   Wortham, Noel ^a   Halford, Sarah ^a   Sieber, Oliver ^a   Mortensen, Neil ^b   Von Herbay, Axel ^c   Gunther, Thomas ^c   Ilyas, Mohammad ^d   Tomlinson, Ian ^a,c  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c ST MARK S HOSPITAL   (United Kingdom)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 4; CYCLIN E; K RAS PROTEIN; MYC PROTEIN; PROTEIN C JUN; PROTEIN P53; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANEUPLOIDY; ARTICLE; CHROMOSOMAL INSTABILITY; COLORECTAL CANCER; CONTROLLED STUDY; DNA REPAIR; FIBROBLAST; FLOW CYTOMETRY; GENE DELETION; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; KNOCKOUT GENE; LYMPHOMA; MICROSATELLITE INSTABILITY; MISSENSE MUTATION; NONSENSE MUTATION; POLYPLOIDY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADENOCARCINOMA; ADENOMA; ADENOMATOUS POLYPOSIS COLI PROTEIN; CELL CYCLE PROTEINS; CHROMOSOMAL INSTABILITY; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; F-BOX PROTEINS; GENES, RAS; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; MUTATION; PLOIDIES; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-PROTEIN LIGASES;

EID: 29244460649     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-2565     Document Type: Article

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