Matrix metalloproteinases in cancer

Essays in Biochemistry

Volumn 38, Issue , 2002, Pages 21-36

  Itoh, Yoshifumi ^a   Nagase, Hideaki ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE 3; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; NEUTROPHIL COLLAGENASE;

ARTICLE; CANCER; CANCER GROWTH; CANCER INVASION; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL MIGRATION; CELL MOTILITY; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME STRUCTURE; EXTRACELLULAR MATRIX; HUMAN; METASTASIS; NEOVASCULARIZATION (PATHOLOGY); PROTEIN DEGRADATION; TUMOR; TUMOR CELL;

EID: 0037509851     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/bse0380021     Document Type: Article

References (24)

1. Werb, Z. (1997) ECM and cell surface proteolysis: regulating cellular ecology. Cell 91, 439-442
2. Nagase, H. & Woessner, Jr, J.F. (1999) Matrix metalloproteinases. J. Biol. Chem. 274, 21491-21494
3. Seiki, M. (1999) Membrane-type matrix metalloproteinases. APMIS 107, 137-143
4. Itoh, Y., Kajita, M., Kinoh, H., Mori, H., Okada, A. & Seiki, M. (1999) Membrane type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosylphosphatidylinositol-anchored proteinase. J. Biol. Chem. 274, 34260-34266
5. Brew, K., Dinakarpandian, D. & Nagase, H. (2000) Tissue inhibitors of metalloproteinases: evolution, structure and function. Biochim. Biophys. Acta 1477, 267-283
6. Liotta, L.A., Thorgeirsson, U.P. & Garbisa, S. (1982) Role of collagenases in tumor cell invasion. Cancer Metastasis Rev. 1, 277-288
7. Fingleton, B. & Matrisian, L.M. (2001) Matrix metalloproteinases in cancer. In Matrix Metalloproteinase Inhibitors in Cancer Therapy (Clendeninn, N.J. & Appelt, K., eds), pp. 85-112, Humana Press, Totowa, NJ
8. Hotary, K., Allen, E., Punturieri, A., Yana, I. & Weiss, S.J. (2000) Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J. Cell Biol. 149, 1309-1323
9. Yu, Q. & Stamenkovic, I. (2000) Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev. 14, 163-176
10. Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E. & Seiki, M. (1994) A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature (London) 370, 61-65
11. Giannelli, G., Falk-Marzillier, J., Schiraldi, O., Stetler-Stevenson, W.G. & Quaranta, V. (1997) Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. Science 277, 225-228
12. Koshikawa, N., Giannelli, G., Cirulli, V., Miyazaki, K. & Quaranta, V. (2000) Role of cell surface metalloprotease MTI-MMP in epithelial cell migration over laminin-5. J. Cell Biol. 148, 615-624
13. Kajita, M., Itoh, Y., Chiba, T., Mori, H., Okada, A., Kinoh, H. & Seiki, M. (2001) Membrane-type I matrix metalloproteinase cleaves CD44 and promotes cell migration. J. Cell Biol. 153, 893-904
14. Itoh, Y., Takamura, A., Ito, N., Maru, Y., Sato, H., Suenaga, N., Aoki, T. & Seiki, M. (2001) Homophilic complex formation of MTI-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion. EMBO J. 20, 4782-4793
15. Bergers, G., Brekken, R., McMahon, G., Vu, T.H., Itoh, T., Tamaki, K., Tanzawa, K., Thorpe, P., Itohara, S., Werb, Z. & Hanahan, D. (2000) Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat. Cell Biol. 2, 737-744
16. Hiraoka, N., Allen, E., Apel, I.J., Gyetko, M.R. & Weiss, S.J. (1998) Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins. Cell 95, 365-377
17. Khokha, R., Waterhouse, P., Yagel, S., Lala, P.K., Overall, C.M., Norton, G. & Denhardt, D.T. (1989) Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells. Science 243, 947-950
18. Montgomery, A.M., Mueller, B.M., Reisfeld, R.A., Taylor, S.M. & DeClerck, Y.A. (1994) Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line. Cancer Res. 54, 5467-5473
19. Koop, S., Khokha, R., Schmidt, E.E., MacDonald, I.C., Morris, V.L., Chambers, A.F. & Groom, A.C. (1994) Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth. Cancer Res. 54, 4791-4797
20. Wilson, C.L., Heppner, K.J., Labosky, P.A., Hogan, B.L. & Matrisian, L.M. (1997) Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin. Proc. Natl. Acad. Sci. U.S.A. 94, 1402-1407
21. Sternlicht, M.D., Lochter, A., Sympson, C.J., Huey, B., Rougier, J.P., Gray, J.W., Pinkel, D., Bissell, M.J. & Werb, Z. (1999) The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis. Cell 98, 137-146
22. Zucker, S., Cao, J. & Chen, W.T. (2000) Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment. Oncogene 19, 6642-6650
23. Gomis-Rüth, F.X., Maskos, K., Betz, M., Bergner, A., Huber, R., Suzuki, K., Yoshida, N., Nagase, H., Brew, K., Bourenkov, G.P. et al. (1997) Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature (London) 389, 77-81
24. Guex, N. & Peitsch, M.C. (1997) SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18, 2714-2723