Notch signaling: Fringe really is a glycosyltransferase

Current Biology

Volumn 10, Issue 16, 2000, Pages

  Blair, Seth S ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034710595     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00633-3     Document Type: Review

References (28)

1. Fringe forms a complex with Notch
2. The Notch signalling regulator Fringe acts in the Golgi apparatus and requires the glycoslytransferase signature motif DxD
3. Glycoslytransferase activity of Fringe modulates Notch-Delta interactions
4. Fringe is a glycosyltransferase that modifies Notch
5. Structural conservation of Notch receptors and ligands
6. Modulators of Notch signalling
7. Fringe: Defining borders by regulating the Notch pathway
8. Processing of the Notch ligand Delta by the metalloprotease Kuzbanian
9. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor
10. Single amino acid substitutions in EGF-like elements of Notch and Delta modify Drosophila development and affect cell adhesion in vitro
11. Functional domains of LAG-2, a putative signaling ligand for LIN-12 and GLP-1 receptors in Caenorhabditis elegans
12. Limb development: Marginal Fringe benefits
13. Fringe, Notch, and making developmental boundaries
14. Fringe modulates Notch-ligand interactions
15. Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing disc
16. Fringe differentially modulates Jagged1 and Delta1 signaling through Notch1 and Notch2 receptors in mammalian cells
17. Interactions among Delta, Serrate and Fringe modulate Notch activity during Drosophila wing development
18. Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: Members of the Notch signalling pathway in Drosophila
19. Secreted Fringe-like signaling molecules may be glycosyltransferases
20. Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules
21. O-linked fucose and other post-translational modifications unique to EGF modules
22. The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe
23. Cis-interactions between Delta and Notch modulate neurogenic signalling in Drosophila
24. Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila
25. Identification and characterization of large galactosyltransferase gene families: Galactosyltransferases for all functions
26. Brainiac and Fringe are similar pioneer proteins that impart specificity to Notch signaling during Drosophila development
27. Proteoglycans and pattern formation: Sugar biochemistry meets developmental genetics
28. Specificities of heparan sulphate proteoglycans in developmental processes