-
1
-
-
33646345376
-
Ubiquitin ligases:cellcycle control and cancer
-
Nakayama KI, Nakayama K. Ubiquitin ligases:cellcycle control and cancer. Nat Rev Cancer 2006; 6: 369-81.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 369-381
-
-
Nakayama, K.I.1
Nakayama, K.2
-
2
-
-
38549086019
-
FBW7 ubiquitin ligase:a tumour suppressor at the crossroads of cell division, growth and differentiation
-
Welcker M, Clurman BE. FBW7 ubiquitin ligase:a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat Rev Cancer 2008; 8: 83-93.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 83-93
-
-
Welcker, M.1
Clurman, B.E.2
-
3
-
-
10644269326
-
Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene
-
Mao JH, Perez-Losada J, Wu D, et al. Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene. Nature 2004; 432: 775-9.
-
(2004)
Nature
, vol.432
, pp. 775-779
-
-
Mao, J.H.1
Perez-Losada, J.2
Wu, D.3
-
4
-
-
35148842479
-
FBXW7/hCDC4 is a general tumor suppressor in human cancer
-
Akhoondi S, Sun D, von der Lehr N, et al. FBXW7/hCDC4 is a general tumor suppressor in human cancer. Cancer Res 2007; 67: 9006-12.
-
(2007)
Cancer Res
, vol.67
, pp. 9006-9012
-
-
Akhoondi, S.1
Sun, D.2
von der Lehr, N.3
-
5
-
-
33749186359
-
Expression of mouse Fbxw7 isoforms is regulated in a cell cycle- or p53-dependent manner
-
Matsumoto A, Onoyama I, Nakayama KI. Expression of mouse Fbxw7 isoforms is regulated in a cell cycle- or p53-dependent manner. Biochem Biophys Res Commun 2006; 350: 114-9.
-
(2006)
Biochem Biophys Res Commun
, vol.350
, pp. 114-119
-
-
Matsumoto, A.1
Onoyama, I.2
Nakayama, K.I.3
-
6
-
-
36549071481
-
Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis
-
Onoyama I, Tsunematsu R, Matsumoto A, et al. Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis. J Exp Med 2007; 204: 2875-88.
-
(2007)
J Exp Med
, vol.204
, pp. 2875-2888
-
-
Onoyama, I.1
Tsunematsu, R.2
Matsumoto, A.3
-
7
-
-
42149132696
-
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL
-
Matsuoka S, Oike Y, Onoyama I, et al. Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL. Genes Dev 2008; 22: 986-91.
-
(2008)
Genes Dev
, vol.22
, pp. 986-991
-
-
Matsuoka, S.1
Oike, Y.2
Onoyama, I.3
-
8
-
-
0038420033
-
hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53
-
Kimura T, Gotoh M, Nakamura Y, Arakawa H. hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53. Cancer Sci 2003; 94: 431-6.
-
(2003)
Cancer Sci
, vol.94
, pp. 431-436
-
-
Kimura, T.1
Gotoh, M.2
Nakamura, Y.3
Arakawa, H.4
-
9
-
-
17044370346
-
Regulation of the cell cycle by SCF-type ubiquitin ligases
-
Nakayama KI, Nakayama K. Regulation of the cell cycle by SCF-type ubiquitin ligases. Semin Cell Dev Biol 2005; 16: 323-33.
-
(2005)
Semin Cell Dev Biol
, vol.16
, pp. 323-333
-
-
Nakayama, K.I.1
Nakayama, K.2
-
10
-
-
33747837463
-
hCDC4 variation in osteosarcoma
-
Yan T, Wunder JS, Gokgoz N, Seto KK, Bell RS, Andrulis IL. hCDC4 variation in osteosarcoma. Cancer Genet Cytogenet 2006; 169: 138-42.
-
(2006)
Cancer Genet Cytogenet
, vol.169
, pp. 138-142
-
-
Yan, T.1
Wunder, J.S.2
Gokgoz, N.3
Seto, K.K.4
Bell, R.S.5
Andrulis, I.L.6
-
11
-
-
34248221516
-
FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients
-
Hagedorn M, Delugin M, Abraldes I, et al. FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients. Cell Div 2007; 2: 9.
-
(2007)
Cell Div
, vol.2
, pp. 9
-
-
Hagedorn, M.1
Delugin, M.2
Abraldes, I.3
-
12
-
-
25444448993
-
Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas
-
Bredel M, Bredel C, Juric D, et al. Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas. Cancer Res 2005; 65: 8679-89.
-
(2005)
Cancer Res
, vol.65
, pp. 8679-8689
-
-
Bredel, M.1
Bredel, C.2
Juric, D.3
-
13
-
-
33748097473
-
Mutational analysis of the hCDC4 gene in gastric carcinomas
-
Lee JW, Soung YH, Kim HJ, et al. Mutational analysis of the hCDC4 gene in gastric carcinomas. Eur J Cancer 2006; 42: 2369-73.
-
(2006)
Eur J Cancer
, vol.42
, pp. 2369-2373
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, H.J.3
-
14
-
-
0036037087
-
Cyclins in breast cancer:too much of a good thing
-
Enders GH. Cyclins in breast cancer:too much of a good thing. Breast Cancer Res 2002; 4: 145-7.
-
(2002)
Breast Cancer Res
, vol.4
, pp. 145-147
-
-
Enders, G.H.1
-
15
-
-
17144391833
-
Clinical significance of human kallikrein gene 6 messenger RNA expression in colorectal cancer
-
Ogawa K, Utsunomiya T, Mimori K, et al. Clinical significance of human kallikrein gene 6 messenger RNA expression in colorectal cancer. Clin Cancer Res 2005; 11: 2889-93.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2889-2893
-
-
Ogawa, K.1
Utsunomiya, T.2
Mimori, K.3
-
16
-
-
34248530332
-
Identification of overexpressed genes in hepatocellular carcinoma, with special reference to ubiquitin-conjugating enzyme E2C gene expression
-
Ieta K, Ojima E, Tanaka F, et al. Identification of overexpressed genes in hepatocellular carcinoma, with special reference to ubiquitin-conjugating enzyme E2C gene expression. Int J Cancer 2007; 121: 33-8.
-
(2007)
Int J Cancer
, vol.121
, pp. 33-38
-
-
Ieta, K.1
Ojima, E.2
Tanaka, F.3
-
17
-
-
33747171944
-
CEACAM6 gene expression in intrahepatic cholangiocarcinoma
-
Ieta K, Tanaka F, Utsunomiya T, Kuwano H, Mori M. CEACAM6 gene expression in intrahepatic cholangiocarcinoma. Br J Cancer 2006; 95: 532-40.
-
(2006)
Br J Cancer
, vol.95
, pp. 532-540
-
-
Ieta, K.1
Tanaka, F.2
Utsunomiya, T.3
Kuwano, H.4
Mori, M.5
-
18
-
-
6944227551
-
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size
-
Welcker M, Orian A, Grim JE, Eisenman RN, Clurman BE. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size. Curr Biol 2004; 14: 1852-7.
-
(2004)
Curr Biol
, vol.14
, pp. 1852-1857
-
-
Welcker, M.1
Orian, A.2
Grim, J.E.3
Eisenman, R.N.4
Clurman, B.E.5
-
19
-
-
34547928992
-
p53 and SCF (Fbw7) cooperatively restrain cyclin E-associated genome instability
-
Minella AC, Grim JE, Welcker M, Clurman BE. p53 and SCF (Fbw7) cooperatively restrain cyclin E-associated genome instability. Oncogene 2007; 26: 6948-53.
-
(2007)
Oncogene
, vol.26
, pp. 6948-6953
-
-
Minella, A.C.1
Grim, J.E.2
Welcker, M.3
Clurman, B.E.4
-
20
-
-
34250837539
-
The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling
-
Malyukova A, Dohda T, von der Lehr N, et al. The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling. Cancer Res 2007; 67: 5611-6.
-
(2007)
Cancer Res
, vol.67
, pp. 5611-5616
-
-
Malyukova, A.1
Dohda, T.2
von der Lehr, N.3
-
21
-
-
53049097854
-
The Fbxw7/hCdc4 tumor suppressor in human cancer
-
Tan Y, Sangfelt O, Spruck C. The Fbxw7/hCdc4 tumor suppressor in human cancer. Cancer Lett 2008; 271: 1-12.
-
(2008)
Cancer Lett
, vol.271
, pp. 1-12
-
-
Tan, Y.1
Sangfelt, O.2
Spruck, C.3
-
22
-
-
33746628060
-
Mutational and LOH analyses of the chromosome 4q region in esophageal adenocarcinoma
-
Sterian A, Kan T, Berki AT, et al. Mutational and LOH analyses of the chromosome 4q region in esophageal adenocarcinoma. Oncology 2006; 70: 168-72.
-
(2006)
Oncology
, vol.70
, pp. 168-172
-
-
Sterian, A.1
Kan, T.2
Berki, A.T.3
-
23
-
-
23844530704
-
Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF (Fbw7)
-
Sundqvist A, Bengoechea-Alonso MT, Ye X, et al. Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF (Fbw7). Cell Metab 2005; 1: 379-91.
-
(2005)
Cell Metab
, vol.1
, pp. 379-391
-
-
Sundqvist, A.1
Bengoechea-Alonso, M.T.2
Ye, X.3
-
24
-
-
15844425850
-
Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization
-
Takada H, Imoto I, Tsuda H, et al. Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization. Cancer Sci 2005; 96: 100-10.
-
(2005)
Cancer Sci
, vol.96
, pp. 100-110
-
-
Takada, H.1
Imoto, I.2
Tsuda, H.3
-
25
-
-
2942650133
-
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
-
Welcker M, Orian A, Jin J, et al. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proc Natl Acad Sci U S A 2004; 101: 9085-90.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9085-9090
-
-
Welcker, M.1
Orian, A.2
Jin, J.3
-
26
-
-
0141591688
-
Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation
-
Welcker M, Singer J, Loeb KR, et al. Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation. Mol Cell 2003; 12: 381-92.
-
(2003)
Mol Cell
, vol.12
, pp. 381-392
-
-
Welcker, M.1
Singer, J.2
Loeb, K.R.3
-
27
-
-
0026096540
-
Control of c-myc regulation in normal and neoplastic cells
-
Spencer CA, Groudine M. Control of c-myc regulation in normal and neoplastic cells. Adv Cancer Res 1991; 56: 1-48.
-
(1991)
Adv Cancer Res
, vol.56
, pp. 1-48
-
-
Spencer, C.A.1
Groudine, M.2
-
28
-
-
33750577506
-
-
Onoyama I. Cyclin E and c-Myc degradation by SCF (Fbxw7). Tanpakushitsu Kakusan Koso 2006; 51: 1382-5.
-
Onoyama I. Cyclin E and c-Myc degradation by SCF (Fbxw7). Tanpakushitsu Kakusan Koso 2006; 51: 1382-5.
-
-
-
-
29
-
-
25444526687
-
Using kinetic studies to uncover new Rb functions in inhibiting cell cycle progression
-
Ji P, Zhu L. Using kinetic studies to uncover new Rb functions in inhibiting cell cycle progression. Cell Cycle 2005; 4: 373-5.
-
(2005)
Cell Cycle
, vol.4
, pp. 373-375
-
-
Ji, P.1
Zhu, L.2
-
30
-
-
0032145569
-
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
-
Zindy F, Eischen CM, Randle DH, et al. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev 1998; 12: 2424-33.
-
(1998)
Genes Dev
, vol.12
, pp. 2424-2433
-
-
Zindy, F.1
Eischen, C.M.2
Randle, D.H.3
-
32
-
-
53349103292
-
Modelling Myc inhibition as a cancer therapy
-
Soucek L, Whitfield J, Martins CP, et al. Modelling Myc inhibition as a cancer therapy. Nature 2008; 455: 679-83.
-
(2008)
Nature
, vol.455
, pp. 679-683
-
-
Soucek, L.1
Whitfield, J.2
Martins, C.P.3
|