Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells

Oncogene

Volumn 35, Issue 11, 2016, Pages 1353-1362

  Dickreuter, E ^a,b   Eke, I ^a,b   Krause, M ^a,b,c   Borgmann, K ^d   Van Vugt, M A ^e   Cordes, N ^a,b,c  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; DOUBLE STRANDED DNA; KU ANTIGEN; NIBRIN; OLAPARIB; RAD50 PROTEIN; SMALL INTERFERING RNA; ANTINEOPLASTIC AGENT; CELL CYCLE PROTEIN; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; DNA LIGASE; MONOCLONAL ANTIBODY; NBN PROTEIN, HUMAN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR PROTEIN; PHTHALAZINE DERIVATIVE; PIPERAZINE DERIVATIVE; RAD50 PROTEIN, HUMAN; RADIOSENSITIZING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER RADIOTHERAPY; CELL SURVIVAL; CLONOGENESIS; CONTROLLED STUDY; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; FEMALE; GENE EXPRESSION; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RADIOSENSITIZATION; TUMOR XENOGRAFT; X IRRADIATION; ANIMAL; BIOSYNTHESIS; CARCINOMA, SQUAMOUS CELL; DRUG EFFECTS; EXTRACELLULAR MATRIX; GENETICS; HEAD AND NECK NEOPLASMS; IMMUNOLOGY; METABOLISM; NUDE MOUSE; RADIATION RESPONSE; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD29; ANTIGENS, NUCLEAR; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; EXTRACELLULAR MATRIX; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MICE; MICE, NUDE; NUCLEAR PROTEINS; PHTHALAZINES; PIPERAZINES; POLY(ADP-RIBOSE) POLYMERASES; RADIATION-SENSITIZING AGENTS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84930995080     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2015.212     Document Type: Article

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