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Volumn 131, Issue 2, 2012, Pages 287-297

The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells

Author keywords

FAK; proliferation; Src; tumour cell migration

Indexed keywords

FOCAL ADHESION KINASE; PF 562271; PROTEIN TYROSINE KINASE;

EID: 84861637416     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26351     Document Type: Article
Times cited : (49)

References (48)
  • 2
    • 0032820782 scopus 로고    scopus 로고
    • Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
    • Sieg DJ, Hauck CR, Schlaepfer DD,. Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration. J Cell Sci 1999; 112: 2677-91.
    • (1999) J Cell Sci , vol.112 , pp. 2677-2691
    • Sieg, D.J.1    Hauck, C.R.2    Schlaepfer, D.D.3
  • 3
    • 0035476836 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells
    • Hauck CR, Sieg DJ, Hsia DA, Loftus JC, Gaarde WA, Monia BP, Schlaepfer DD,. Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells. Cancer Res 2001; 61: 7079-90.
    • (2001) Cancer Res , vol.61 , pp. 7079-7090
    • Hauck, C.R.1    Sieg, D.J.2    Hsia, D.A.3    Loftus, J.C.4    Gaarde, W.A.5    Monia, B.P.6    Schlaepfer, D.D.7
  • 5
    • 2342627918 scopus 로고    scopus 로고
    • Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells
    • Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE,. Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells. Surgery 2004; 135: 555-62.
    • (2004) Surgery , vol.135 , pp. 555-562
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3    Ashley, S.W.4    Whang, E.E.5
  • 6
    • 0029739950 scopus 로고    scopus 로고
    • Control of adhesion-dependent cell survival by focal adhesion kinase
    • Frisch SM, Vuori K, Ruoslahti E, Chan-Hui PY,. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 1996; 134: 793-9.
    • (1996) J Cell Biol , vol.134 , pp. 793-799
    • Frisch, S.M.1    Vuori, K.2    Ruoslahti, E.3    Chan-Hui, P.Y.4
  • 8
    • 9144256723 scopus 로고    scopus 로고
    • Squamous cell carcinoma cell aggregates escape suspension-induced, p53-mediated anoikis: Fibronectin and integrin alphav mediate survival signals through focal adhesion kinase
    • Zhang Y, Lu H, Dazin P, Kapila Y,. Squamous cell carcinoma cell aggregates escape suspension-induced, p53-mediated anoikis: fibronectin and integrin alphav mediate survival signals through focal adhesion kinase. J Biol Chem 2004; 279: 48342-9.
    • (2004) J Biol Chem , vol.279 , pp. 48342-48349
    • Zhang, Y.1    Lu, H.2    Dazin, P.3    Kapila, Y.4
  • 9
    • 0032443850 scopus 로고    scopus 로고
    • The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells
    • Xu LH, Yang X, Craven RJ, Cance WG,. The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells. Cell Growth Differ 1998; 9: 999-1005.
    • (1998) Cell Growth Differ , vol.9 , pp. 999-1005
    • Xu, L.H.1    Yang, X.2    Craven, R.J.3    Cance, W.G.4
  • 12
    • 58349108303 scopus 로고    scopus 로고
    • Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells
    • Luo M, Fan H, Nagy T, Wei H, Wang C, Liu S, Wicha MS, Guan JL,. Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells. Cancer Res 2009; 69: 466-74.
    • (2009) Cancer Res , vol.69 , pp. 466-474
    • Luo, M.1    Fan, H.2    Nagy, T.3    Wei, H.4    Wang, C.5    Liu, S.6    Wicha, M.S.7    Guan, J.L.8
  • 13
    • 55349105491 scopus 로고    scopus 로고
    • Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer
    • Provenzano PP, Inman DR, Eliceiri KW, Beggs HE, Keely PJ,. Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer. Am J Pathol 2008; 173: 1551-65.
    • (2008) Am J Pathol , vol.173 , pp. 1551-1565
    • Provenzano, P.P.1    Inman, D.R.2    Eliceiri, K.W.3    Beggs, H.E.4    Keely, P.J.5
  • 14
    • 61749094852 scopus 로고    scopus 로고
    • Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling
    • Pylayeva Y, Gillen KM, Gerald W, Beggs HE, Reichardt LF, Giancotti FG,. Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. J Clin Invest 2009; 119: 252-66.
    • (2009) J Clin Invest , vol.119 , pp. 252-266
    • Pylayeva, Y.1    Gillen, K.M.2    Gerald, W.3    Beggs, H.E.4    Reichardt, L.F.5    Giancotti, F.G.6
  • 15
    • 68849114514 scopus 로고    scopus 로고
    • Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model
    • Slack-Davis JK, Hershey ED, Theodorescu D, Frierson HF, Parsons JT,. Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model. Mol Cancer Ther 2009; 8: 2470-7.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2470-2477
    • Slack-Davis, J.K.1    Hershey, E.D.2    Theodorescu, D.3    Frierson, H.F.4    Parsons, J.T.5
  • 16
    • 0038048222 scopus 로고    scopus 로고
    • FAK regulates biological processes important for the pathogenesis of cancer
    • Gabarra-Niecko V, Schaller MD, Dunty JM,. FAK regulates biological processes important for the pathogenesis of cancer. Cancer Metastasis Rev 2003; 22: 359-74.
    • (2003) Cancer Metastasis Rev , vol.22 , pp. 359-374
    • Gabarra-Niecko, V.1    Schaller, M.D.2    Dunty, J.M.3
  • 17
    • 33745186178 scopus 로고    scopus 로고
    • The signaling and biological implications of FAK overexpression in cancer
    • Siesser PM, Hanks SK,. The signaling and biological implications of FAK overexpression in cancer. Clin Cancer Res 2006; 12: 3233-7.
    • (2006) Clin Cancer Res , vol.12 , pp. 3233-3237
    • Siesser, P.M.1    Hanks, S.K.2
  • 18
    • 33846554255 scopus 로고    scopus 로고
    • Focal adhesion kinase: A potential target in cancer therapy
    • van Nimwegen MJ, van de Water B,. Focal adhesion kinase: a potential target in cancer therapy. Biochem Pharmacol 2007; 73: 597-609.
    • (2007) Biochem Pharmacol , vol.73 , pp. 597-609
    • Van Nimwegen, M.J.1    Van De Water, B.2
  • 20
    • 51449088226 scopus 로고    scopus 로고
    • Src and focal adhesion kinase as therapeutic targets in cancer
    • Brunton VG, Frame MC,. Src and focal adhesion kinase as therapeutic targets in cancer. Curr Opin Pharmacol 2008; 8: 427-32.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 427-432
    • Brunton, V.G.1    Frame, M.C.2
  • 22
    • 0029948080 scopus 로고    scopus 로고
    • Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
    • Cary LA, Chang JF, Guan JL,. Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J Cell Sci 1996; 109: 1787-94.
    • (1996) J Cell Sci , vol.109 , pp. 1787-1794
    • Cary, L.A.1    Chang, J.F.2    Guan, J.L.3
  • 23
    • 0034717285 scopus 로고    scopus 로고
    • Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60
    • Sonoda Y, Matsumoto Y, Funakoshi M, Yamamoto D, Hanks SK, Kasahara T,. Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60. J Biol Chem 2000; 275: 16309-15.
    • (2000) J Biol Chem , vol.275 , pp. 16309-16315
    • Sonoda, Y.1    Matsumoto, Y.2    Funakoshi, M.3    Yamamoto, D.4    Hanks, S.K.5    Kasahara, T.6
  • 24
    • 32944475609 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells
    • Garces CA, Kurenova EV, Golubovskaya VM, Cance WG,. Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells. Cancer Res 2006; 66: 1446-54.
    • (2006) Cancer Res , vol.66 , pp. 1446-1454
    • Garces, C.A.1    Kurenova, E.V.2    Golubovskaya, V.M.3    Cance, W.G.4
  • 28
    • 67650504966 scopus 로고    scopus 로고
    • TScratch: A novel and simple software tool for automated analysis of monolayer wound healing assays
    • Geback T, Schulz MM, Koumoutsakos P, Detmar M,. TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays. Biotechniques 2009; 46: 265-74.
    • (2009) Biotechniques , vol.46 , pp. 265-274
    • Geback, T.1    Schulz, M.M.2    Koumoutsakos, P.3    Detmar, M.4
  • 29
    • 34347230544 scopus 로고    scopus 로고
    • Sulforhodamine B colorimetric assay for cytotoxicity screening
    • Vichai V, Kirtikara K,. Sulforhodamine B colorimetric assay for cytotoxicity screening. Nat Protoc 2006; 1: 1112-16.
    • (2006) Nat Protoc , vol.1 , pp. 1112-1116
    • Vichai, V.1    Kirtikara, K.2
  • 30
    • 0032531732 scopus 로고    scopus 로고
    • Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration
    • Sieg DJ, Ilic D, Jones KC, Damsky CH, Hunter T, Schlaepfer DD,. Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration. EMBO J 1998; 17: 5933-47.
    • (1998) EMBO J , vol.17 , pp. 5933-5947
    • Sieg, D.J.1    Ilic, D.2    Jones, K.C.3    Damsky, C.H.4    Hunter, T.5    Schlaepfer, D.D.6
  • 32
    • 79151480076 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells
    • Hiscox S, Barnfather P, Hayes E, Bramble P, Christensen J, Nicholson RI, Barrett-Lee P,. Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells. Breast Cancer Res Treat 2011; 125: 659-69.
    • (2011) Breast Cancer Res Treat , vol.125 , pp. 659-669
    • Hiscox, S.1    Barnfather, P.2    Hayes, E.3    Bramble, P.4    Christensen, J.5    Nicholson, R.I.6    Barrett-Lee, P.7
  • 34
    • 78549246804 scopus 로고    scopus 로고
    • Quantitative in vivo imaging of the effects of inhibiting integrin signaling via Src and FAK on cancer cell movement: Effects on E-cadherin dynamics
    • Canel M, Serrels A, Miller D, Timpson P, Serrels B, Frame MC, Brunton VG,. Quantitative in vivo imaging of the effects of inhibiting integrin signaling via Src and FAK on cancer cell movement: effects on E-cadherin dynamics. Cancer Res 2010; 70: 9413-22.
    • (2010) Cancer Res , vol.70 , pp. 9413-9422
    • Canel, M.1    Serrels, A.2    Miller, D.3    Timpson, P.4    Serrels, B.5    Frame, M.C.6    Brunton, V.G.7
  • 35
    • 0038433306 scopus 로고    scopus 로고
    • Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression
    • Zhao J, Bian ZC, Yee K, Chen BP, Chien S, Guan JL,. Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression. Mol Cell 2003; 11: 1503-15.
    • (2003) Mol Cell , vol.11 , pp. 1503-1515
    • Zhao, J.1    Bian, Z.C.2    Yee, K.3    Chen, B.P.4    Chien, S.5    Guan, J.L.6
  • 36
    • 0035661624 scopus 로고    scopus 로고
    • Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression
    • Zhao J, Pestell R, Guan JL,. Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression. Mol Biol Cell 2001; 12: 4066-77.
    • (2001) Mol Biol Cell , vol.12 , pp. 4066-4077
    • Zhao, J.1    Pestell, R.2    Guan, J.L.3
  • 37
    • 14844327984 scopus 로고    scopus 로고
    • P27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the SCID mouse brain
    • Ding Q, Grammer JR, Nelson MA, Guan JL, Stewart JE, Jr., Gladson CL,. p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the SCID mouse brain. J Biol Chem 2005; 280: 6802-15.
    • (2005) J Biol Chem , vol.280 , pp. 6802-6815
    • Ding, Q.1    Grammer, J.R.2    Nelson, M.A.3    Guan, J.L.4    Stewart Jr., J.E.5    Gladson, C.L.6
  • 38
    • 67649849871 scopus 로고    scopus 로고
    • Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs
    • Shibue T, Weinberg RA,. Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc Natl Acad Sci USA 2009; 106: 10290-5.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 10290-10295
    • Shibue, T.1    Weinberg, R.A.2
  • 40
    • 66349129097 scopus 로고    scopus 로고
    • Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts
    • Schwock J, Dhani N, Cao MP, Zheng J, Clarkson R, Radulovich N, Navab R, Horn LC, Hedley DW,. Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts. Cancer Res 2009; 69: 4750-9.
    • (2009) Cancer Res , vol.69 , pp. 4750-4759
    • Schwock, J.1    Dhani, N.2    Cao, M.P.3    Zheng, J.4    Clarkson, R.5    Radulovich, N.6    Navab, R.7    Horn, L.C.8    Hedley, D.W.9
  • 42
    • 0032866076 scopus 로고    scopus 로고
    • Cas mediates transcriptional activation of the serum response element by Src
    • Hakak Y, Martin GS,. Cas mediates transcriptional activation of the serum response element by Src. Mol Cell Biol 1999; 19: 6953-62.
    • (1999) Mol Cell Biol , vol.19 , pp. 6953-6962
    • Hakak, Y.1    Martin, G.S.2
  • 43
    • 0033612572 scopus 로고    scopus 로고
    • Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle
    • Oktay M, Wary KK, Dans M, Birge RB, Giancotti FG,. Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle. J Cell Biol 1999; 145: 1461-9.
    • (1999) J Cell Biol , vol.145 , pp. 1461-1469
    • Oktay, M.1    Wary, K.K.2    Dans, M.3    Birge, R.B.4    Giancotti, F.G.5
  • 46
    • 43049114924 scopus 로고    scopus 로고
    • Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors: Implications for bone metastases
    • Bagi CM, Roberts GW, Andresen CJ,. Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors: implications for bone metastases. Cancer 2008; 112: 2313-21.
    • (2008) Cancer , vol.112 , pp. 2313-2321
    • Bagi, C.M.1    Roberts, G.W.2    Andresen, C.J.3
  • 47
    • 77954406994 scopus 로고    scopus 로고
    • Bioluminescent imaging study: FAK inhibitor, PF-562,271, preclinical study in PC3M-luc-C6 local implant and metastasis xenograft models
    • Sun H, Pisle S, Gardner ER, Figg WD,. Bioluminescent imaging study: FAK inhibitor, PF-562,271, preclinical study in PC3M-luc-C6 local implant and metastasis xenograft models. Cancer Biol Ther 2010; 10: 38-43.
    • (2010) Cancer Biol Ther , vol.10 , pp. 38-43
    • Sun, H.1    Pisle, S.2    Gardner, E.R.3    Figg, W.D.4
  • 48
    • 78649987710 scopus 로고    scopus 로고
    • Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression
    • Wendt MK, Smith JA, Schiemann WP,. Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression. Oncogene 2010; 29: 6485-98.
    • (2010) Oncogene , vol.29 , pp. 6485-6498
    • Wendt, M.K.1    Smith, J.A.2    Schiemann, W.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.