-
1
-
-
0029120440
-
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
-
Ilic D, Furuta Y, Kanazawa S, Takeda N, Sobue K, Nakatsuji N, Nomura S, Fujimoto J, Okada M, Yamamoto T,. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 1995; 377: 539-44.
-
(1995)
Nature
, vol.377
, pp. 539-544
-
-
Ilic, D.1
Furuta, Y.2
Kanazawa, S.3
Takeda, N.4
Sobue, K.5
Nakatsuji, N.6
Nomura, S.7
Fujimoto, J.8
Okada, M.9
Yamamoto, T.10
-
2
-
-
0032820782
-
Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
-
Sieg DJ, Hauck CR, Schlaepfer DD,. Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration. J Cell Sci 1999; 112: 2677-91.
-
(1999)
J Cell Sci
, vol.112
, pp. 2677-2691
-
-
Sieg, D.J.1
Hauck, C.R.2
Schlaepfer, D.D.3
-
3
-
-
0035476836
-
Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells
-
Hauck CR, Sieg DJ, Hsia DA, Loftus JC, Gaarde WA, Monia BP, Schlaepfer DD,. Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells. Cancer Res 2001; 61: 7079-90.
-
(2001)
Cancer Res
, vol.61
, pp. 7079-7090
-
-
Hauck, C.R.1
Sieg, D.J.2
Hsia, D.A.3
Loftus, J.C.4
Gaarde, W.A.5
Monia, B.P.6
Schlaepfer, D.D.7
-
4
-
-
0033772308
-
FAK integrates growth-factor and integrin signals to promote cell migration
-
Sieg DJ, Hauck CR, Ilic D, Klingbeil CK, Schaefer E, Damsky CH, Schlaepfer DD,. FAK integrates growth-factor and integrin signals to promote cell migration. Nat Cell Biol 2000; 2: 249-56.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 249-256
-
-
Sieg, D.J.1
Hauck, C.R.2
Ilic, D.3
Klingbeil, C.K.4
Schaefer, E.5
Damsky, C.H.6
Schlaepfer, D.D.7
-
5
-
-
2342627918
-
Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells
-
Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE,. Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells. Surgery 2004; 135: 555-62.
-
(2004)
Surgery
, vol.135
, pp. 555-562
-
-
Duxbury, M.S.1
Ito, H.2
Zinner, M.J.3
Ashley, S.W.4
Whang, E.E.5
-
6
-
-
0029739950
-
Control of adhesion-dependent cell survival by focal adhesion kinase
-
Frisch SM, Vuori K, Ruoslahti E, Chan-Hui PY,. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 1996; 134: 793-9.
-
(1996)
J Cell Biol
, vol.134
, pp. 793-799
-
-
Frisch, S.M.1
Vuori, K.2
Ruoslahti, E.3
Chan-Hui, P.Y.4
-
7
-
-
0030300180
-
Inhibition of pp125FAK in cultured fibroblasts results in apoptosis
-
Hungerford JE, Compton MT, Matter ML, Hoffstrom BG, Otey CA,. Inhibition of pp125FAK in cultured fibroblasts results in apoptosis. J Cell Biol 1996; 135: 1383-90.
-
(1996)
J Cell Biol
, vol.135
, pp. 1383-1390
-
-
Hungerford, J.E.1
Compton, M.T.2
Matter, M.L.3
Hoffstrom, B.G.4
Otey, C.A.5
-
8
-
-
9144256723
-
Squamous cell carcinoma cell aggregates escape suspension-induced, p53-mediated anoikis: Fibronectin and integrin alphav mediate survival signals through focal adhesion kinase
-
Zhang Y, Lu H, Dazin P, Kapila Y,. Squamous cell carcinoma cell aggregates escape suspension-induced, p53-mediated anoikis: fibronectin and integrin alphav mediate survival signals through focal adhesion kinase. J Biol Chem 2004; 279: 48342-9.
-
(2004)
J Biol Chem
, vol.279
, pp. 48342-48349
-
-
Zhang, Y.1
Lu, H.2
Dazin, P.3
Kapila, Y.4
-
9
-
-
0032443850
-
The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells
-
Xu LH, Yang X, Craven RJ, Cance WG,. The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells. Cell Growth Differ 1998; 9: 999-1005.
-
(1998)
Cell Growth Differ
, vol.9
, pp. 999-1005
-
-
Xu, L.H.1
Yang, X.2
Craven, R.J.3
Cance, W.G.4
-
10
-
-
10644280092
-
Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression
-
McLean GW, Komiyama NH, Serrels B, Asano H, Reynolds L, Conti F, Hodivala-Dilke K, Metzger D, Chambon P, Grant SG, Frame MC,. Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. Genes Dev 2004; 18: 2998-3003.
-
(2004)
Genes Dev
, vol.18
, pp. 2998-3003
-
-
McLean, G.W.1
Komiyama, N.H.2
Serrels, B.3
Asano, H.4
Reynolds, L.5
Conti, F.6
Hodivala-Dilke, K.7
Metzger, D.8
Chambon, P.9
Grant, S.G.10
Frame, M.C.11
-
11
-
-
38049098089
-
Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression
-
Lahlou H, Sanguin-Gendreau V, Zuo D, Cardiff RD, McLean GW, Frame MC, Muller WJ,. Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression. Proc Natl Acad Sci USA 2007; 104: 20302-7.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20302-20307
-
-
Lahlou, H.1
Sanguin-Gendreau, V.2
Zuo, D.3
Cardiff, R.D.4
McLean, G.W.5
Frame, M.C.6
Muller, W.J.7
-
12
-
-
58349108303
-
Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells
-
Luo M, Fan H, Nagy T, Wei H, Wang C, Liu S, Wicha MS, Guan JL,. Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells. Cancer Res 2009; 69: 466-74.
-
(2009)
Cancer Res
, vol.69
, pp. 466-474
-
-
Luo, M.1
Fan, H.2
Nagy, T.3
Wei, H.4
Wang, C.5
Liu, S.6
Wicha, M.S.7
Guan, J.L.8
-
13
-
-
55349105491
-
Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer
-
Provenzano PP, Inman DR, Eliceiri KW, Beggs HE, Keely PJ,. Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer. Am J Pathol 2008; 173: 1551-65.
-
(2008)
Am J Pathol
, vol.173
, pp. 1551-1565
-
-
Provenzano, P.P.1
Inman, D.R.2
Eliceiri, K.W.3
Beggs, H.E.4
Keely, P.J.5
-
14
-
-
61749094852
-
Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling
-
Pylayeva Y, Gillen KM, Gerald W, Beggs HE, Reichardt LF, Giancotti FG,. Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. J Clin Invest 2009; 119: 252-66.
-
(2009)
J Clin Invest
, vol.119
, pp. 252-266
-
-
Pylayeva, Y.1
Gillen, K.M.2
Gerald, W.3
Beggs, H.E.4
Reichardt, L.F.5
Giancotti, F.G.6
-
15
-
-
68849114514
-
Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model
-
Slack-Davis JK, Hershey ED, Theodorescu D, Frierson HF, Parsons JT,. Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model. Mol Cancer Ther 2009; 8: 2470-7.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2470-2477
-
-
Slack-Davis, J.K.1
Hershey, E.D.2
Theodorescu, D.3
Frierson, H.F.4
Parsons, J.T.5
-
16
-
-
0038048222
-
FAK regulates biological processes important for the pathogenesis of cancer
-
Gabarra-Niecko V, Schaller MD, Dunty JM,. FAK regulates biological processes important for the pathogenesis of cancer. Cancer Metastasis Rev 2003; 22: 359-74.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 359-374
-
-
Gabarra-Niecko, V.1
Schaller, M.D.2
Dunty, J.M.3
-
17
-
-
33745186178
-
The signaling and biological implications of FAK overexpression in cancer
-
Siesser PM, Hanks SK,. The signaling and biological implications of FAK overexpression in cancer. Clin Cancer Res 2006; 12: 3233-7.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3233-3237
-
-
Siesser, P.M.1
Hanks, S.K.2
-
18
-
-
33846554255
-
Focal adhesion kinase: A potential target in cancer therapy
-
van Nimwegen MJ, van de Water B,. Focal adhesion kinase: a potential target in cancer therapy. Biochem Pharmacol 2007; 73: 597-609.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 597-609
-
-
Van Nimwegen, M.J.1
Van De Water, B.2
-
19
-
-
21744435478
-
The role of focal-adhesion kinase in cancer - A new therapeutic opportunity
-
McLean GW, Carragher NO, Avizienyte E, Evans J, Brunton VG, Frame MC,. The role of focal-adhesion kinase in cancer - a new therapeutic opportunity. Nat Rev Cancer 2005; 5: 505-15.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 505-515
-
-
McLean, G.W.1
Carragher, N.O.2
Avizienyte, E.3
Evans, J.4
Brunton, V.G.5
Frame, M.C.6
-
20
-
-
51449088226
-
Src and focal adhesion kinase as therapeutic targets in cancer
-
Brunton VG, Frame MC,. Src and focal adhesion kinase as therapeutic targets in cancer. Curr Opin Pharmacol 2008; 8: 427-32.
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 427-432
-
-
Brunton, V.G.1
Frame, M.C.2
-
21
-
-
40949152523
-
Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271
-
Roberts WG, Ung E, Whalen P, Cooper B, Hulford C, Autry C, Richter D, Emerson E, Lin J, Kath J, Coleman K, Yao L, et al. Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271. Cancer Res 2008; 68: 1935-44.
-
(2008)
Cancer Res
, vol.68
, pp. 1935-1944
-
-
Roberts, W.G.1
Ung, E.2
Whalen, P.3
Cooper, B.4
Hulford, C.5
Autry, C.6
Richter, D.7
Emerson, E.8
Lin, J.9
Kath, J.10
Coleman, K.11
Yao, L.12
-
22
-
-
0029948080
-
Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
-
Cary LA, Chang JF, Guan JL,. Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J Cell Sci 1996; 109: 1787-94.
-
(1996)
J Cell Sci
, vol.109
, pp. 1787-1794
-
-
Cary, L.A.1
Chang, J.F.2
Guan, J.L.3
-
23
-
-
0034717285
-
Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60
-
Sonoda Y, Matsumoto Y, Funakoshi M, Yamamoto D, Hanks SK, Kasahara T,. Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60. J Biol Chem 2000; 275: 16309-15.
-
(2000)
J Biol Chem
, vol.275
, pp. 16309-16315
-
-
Sonoda, Y.1
Matsumoto, Y.2
Funakoshi, M.3
Yamamoto, D.4
Hanks, S.K.5
Kasahara, T.6
-
24
-
-
32944475609
-
Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells
-
Garces CA, Kurenova EV, Golubovskaya VM, Cance WG,. Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells. Cancer Res 2006; 66: 1446-54.
-
(2006)
Cancer Res
, vol.66
, pp. 1446-1454
-
-
Garces, C.A.1
Kurenova, E.V.2
Golubovskaya, V.M.3
Cance, W.G.4
-
25
-
-
77954543000
-
A complex between FAK, RACK1 and PDE4D5 controls spreading initiation and cancer cell polarity
-
Serrels B, Sandilands E, Serrels A, Baillie G, Houslay MD, Brunton VG, Canel M, Machesky LM, Anderson KI, Frame MC,. A complex between FAK, RACK1 and PDE4D5 controls spreading initiation and cancer cell polarity. Curr Biol 2010; 20: 1086-92.
-
(2010)
Curr Biol
, vol.20
, pp. 1086-1092
-
-
Serrels, B.1
Sandilands, E.2
Serrels, A.3
Baillie, G.4
Houslay, M.D.5
Brunton, V.G.6
Canel, M.7
Machesky, L.M.8
Anderson, K.I.9
Frame, M.C.10
-
26
-
-
34548316989
-
Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex
-
Serrels B, Serrels A, Brunton VG, Holt M, McLean GW, Gray CH, Jones GE, Frame MC,. Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex. Nat Cell Biol 2007; 9: 1046-56.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1046-1056
-
-
Serrels, B.1
Serrels, A.2
Brunton, V.G.3
Holt, M.4
McLean, G.W.5
Gray, C.H.6
Jones, G.E.7
Frame, M.C.8
-
27
-
-
33846241683
-
Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib
-
Serrels A, Macpherson IR, Evans TR, Lee FY, Clark EA, Sansom OJ, Ashton GH, Frame MC, Brunton VG,. Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib. Mol Cancer Ther 2006; 5: 3014-22.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 3014-3022
-
-
Serrels, A.1
Macpherson, I.R.2
Evans, T.R.3
Lee, F.Y.4
Clark, E.A.5
Sansom, O.J.6
Ashton, G.H.7
Frame, M.C.8
Brunton, V.G.9
-
28
-
-
67650504966
-
TScratch: A novel and simple software tool for automated analysis of monolayer wound healing assays
-
Geback T, Schulz MM, Koumoutsakos P, Detmar M,. TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays. Biotechniques 2009; 46: 265-74.
-
(2009)
Biotechniques
, vol.46
, pp. 265-274
-
-
Geback, T.1
Schulz, M.M.2
Koumoutsakos, P.3
Detmar, M.4
-
29
-
-
34347230544
-
Sulforhodamine B colorimetric assay for cytotoxicity screening
-
Vichai V, Kirtikara K,. Sulforhodamine B colorimetric assay for cytotoxicity screening. Nat Protoc 2006; 1: 1112-16.
-
(2006)
Nat Protoc
, vol.1
, pp. 1112-1116
-
-
Vichai, V.1
Kirtikara, K.2
-
30
-
-
0032531732
-
Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration
-
Sieg DJ, Ilic D, Jones KC, Damsky CH, Hunter T, Schlaepfer DD,. Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration. EMBO J 1998; 17: 5933-47.
-
(1998)
EMBO J
, vol.17
, pp. 5933-5947
-
-
Sieg, D.J.1
Ilic, D.2
Jones, K.C.3
Damsky, C.H.4
Hunter, T.5
Schlaepfer, D.D.6
-
31
-
-
34447538483
-
Cellular characterization of a novel focal adhesion kinase inhibitor
-
Slack-Davis JK, Martin KH, Tilghman RW, Iwanicki M, Ung EJ, Autry C, Luzzio MJ, Cooper B, Kath JC, Roberts WG, Parsons JT,. Cellular characterization of a novel focal adhesion kinase inhibitor. J Biol Chem 2007; 282: 14845-52.
-
(2007)
J Biol Chem
, vol.282
, pp. 14845-14852
-
-
Slack-Davis, J.K.1
Martin, K.H.2
Tilghman, R.W.3
Iwanicki, M.4
Ung, E.J.5
Autry, C.6
Luzzio, M.J.7
Cooper, B.8
Kath, J.C.9
Roberts, W.G.10
Parsons, J.T.11
-
32
-
-
79151480076
-
Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells
-
Hiscox S, Barnfather P, Hayes E, Bramble P, Christensen J, Nicholson RI, Barrett-Lee P,. Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells. Breast Cancer Res Treat 2011; 125: 659-69.
-
(2011)
Breast Cancer Res Treat
, vol.125
, pp. 659-669
-
-
Hiscox, S.1
Barnfather, P.2
Hayes, E.3
Bramble, P.4
Christensen, J.5
Nicholson, R.I.6
Barrett-Lee, P.7
-
33
-
-
77953709612
-
PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments
-
Tanjoni I, Walsh C, Uryu S, Tomar A, Nam JO, Mielgo A, Lim ST, Liang C, Koenig M, Sun C, Patel N, Kwok C, et al. PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments. Cancer Biol Ther 2010; 9: 764-77.
-
(2010)
Cancer Biol Ther
, vol.9
, pp. 764-777
-
-
Tanjoni, I.1
Walsh, C.2
Uryu, S.3
Tomar, A.4
Nam, J.O.5
Mielgo, A.6
Lim, S.T.7
Liang, C.8
Koenig, M.9
Sun, C.10
Patel, N.11
Kwok, C.12
-
34
-
-
78549246804
-
Quantitative in vivo imaging of the effects of inhibiting integrin signaling via Src and FAK on cancer cell movement: Effects on E-cadherin dynamics
-
Canel M, Serrels A, Miller D, Timpson P, Serrels B, Frame MC, Brunton VG,. Quantitative in vivo imaging of the effects of inhibiting integrin signaling via Src and FAK on cancer cell movement: effects on E-cadherin dynamics. Cancer Res 2010; 70: 9413-22.
-
(2010)
Cancer Res
, vol.70
, pp. 9413-9422
-
-
Canel, M.1
Serrels, A.2
Miller, D.3
Timpson, P.4
Serrels, B.5
Frame, M.C.6
Brunton, V.G.7
-
35
-
-
0038433306
-
Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression
-
Zhao J, Bian ZC, Yee K, Chen BP, Chien S, Guan JL,. Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression. Mol Cell 2003; 11: 1503-15.
-
(2003)
Mol Cell
, vol.11
, pp. 1503-1515
-
-
Zhao, J.1
Bian, Z.C.2
Yee, K.3
Chen, B.P.4
Chien, S.5
Guan, J.L.6
-
36
-
-
0035661624
-
Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression
-
Zhao J, Pestell R, Guan JL,. Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression. Mol Biol Cell 2001; 12: 4066-77.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 4066-4077
-
-
Zhao, J.1
Pestell, R.2
Guan, J.L.3
-
37
-
-
14844327984
-
P27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the SCID mouse brain
-
Ding Q, Grammer JR, Nelson MA, Guan JL, Stewart JE, Jr., Gladson CL,. p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the SCID mouse brain. J Biol Chem 2005; 280: 6802-15.
-
(2005)
J Biol Chem
, vol.280
, pp. 6802-6815
-
-
Ding, Q.1
Grammer, J.R.2
Nelson, M.A.3
Guan, J.L.4
Stewart Jr., J.E.5
Gladson, C.L.6
-
38
-
-
67649849871
-
Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs
-
Shibue T, Weinberg RA,. Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc Natl Acad Sci USA 2009; 106: 10290-5.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 10290-10295
-
-
Shibue, T.1
Weinberg, R.A.2
-
39
-
-
70350574674
-
An integrin α(v)β(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression
-
Desgrosellier JS, Barnes LA, Shields DJ, Huang M, Lau SK, Prevost N, Tarin D, Shattil SJ, Cheresh DA,. An integrin α(v)β(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nat Med 2009; 15: 1163-9.
-
(2009)
Nat Med
, vol.15
, pp. 1163-1169
-
-
Desgrosellier, J.S.1
Barnes, L.A.2
Shields, D.J.3
Huang, M.4
Lau, S.K.5
Prevost, N.6
Tarin, D.7
Shattil, S.J.8
Cheresh, D.A.9
-
40
-
-
66349129097
-
Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts
-
Schwock J, Dhani N, Cao MP, Zheng J, Clarkson R, Radulovich N, Navab R, Horn LC, Hedley DW,. Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts. Cancer Res 2009; 69: 4750-9.
-
(2009)
Cancer Res
, vol.69
, pp. 4750-4759
-
-
Schwock, J.1
Dhani, N.2
Cao, M.P.3
Zheng, J.4
Clarkson, R.5
Radulovich, N.6
Navab, R.7
Horn, L.C.8
Hedley, D.W.9
-
41
-
-
0032416722
-
The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway
-
Dolfi F, Garcia-Guzman M, Ojaniemi M, Nakamura H, Matsuda M, Vuori K,. The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway. Proc Natl Acad Sci USA 1998; 95: 15394-9.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15394-15399
-
-
Dolfi, F.1
Garcia-Guzman, M.2
Ojaniemi, M.3
Nakamura, H.4
Matsuda, M.5
Vuori, K.6
-
42
-
-
0032866076
-
Cas mediates transcriptional activation of the serum response element by Src
-
Hakak Y, Martin GS,. Cas mediates transcriptional activation of the serum response element by Src. Mol Cell Biol 1999; 19: 6953-62.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6953-6962
-
-
Hakak, Y.1
Martin, G.S.2
-
43
-
-
0033612572
-
Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle
-
Oktay M, Wary KK, Dans M, Birge RB, Giancotti FG,. Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle. J Cell Biol 1999; 145: 1461-9.
-
(1999)
J Cell Biol
, vol.145
, pp. 1461-1469
-
-
Oktay, M.1
Wary, K.K.2
Dans, M.3
Birge, R.B.4
Giancotti, F.G.5
-
44
-
-
33646422461
-
P130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis
-
Cabodi S, Tinnirello A, Di Stefano P, Bisaro B, Ambrosino E, Castellano I, Sapino A, Arisio R, Cavallo F, Forni G, Glukhova M, Silengo L, et al. p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis. Cancer Res 2006; 66: 4672-80.
-
(2006)
Cancer Res
, vol.66
, pp. 4672-4680
-
-
Cabodi, S.1
Tinnirello, A.2
Di Stefano, P.3
Bisaro, B.4
Ambrosino, E.5
Castellano, I.6
Sapino, A.7
Arisio, R.8
Cavallo, F.9
Forni, G.10
Glukhova, M.11
Silengo, L.12
-
45
-
-
77953898050
-
Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma
-
Morton JP, Karim SA, Graham K, Timpson P, Jamieson N, Athineos D, Doyle B, McKay C, Heung MY, Oien KA, Frame MC, Evans TR, et al. Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma. Gastroenterology 2010; 139: 292-303.
-
(2010)
Gastroenterology
, vol.139
, pp. 292-303
-
-
Morton, J.P.1
Karim, S.A.2
Graham, K.3
Timpson, P.4
Jamieson, N.5
Athineos, D.6
Doyle, B.7
McKay, C.8
Heung, M.Y.9
Oien, K.A.10
Frame, M.C.11
Evans, T.R.12
-
46
-
-
43049114924
-
Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors: Implications for bone metastases
-
Bagi CM, Roberts GW, Andresen CJ,. Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors: implications for bone metastases. Cancer 2008; 112: 2313-21.
-
(2008)
Cancer
, vol.112
, pp. 2313-2321
-
-
Bagi, C.M.1
Roberts, G.W.2
Andresen, C.J.3
-
47
-
-
77954406994
-
Bioluminescent imaging study: FAK inhibitor, PF-562,271, preclinical study in PC3M-luc-C6 local implant and metastasis xenograft models
-
Sun H, Pisle S, Gardner ER, Figg WD,. Bioluminescent imaging study: FAK inhibitor, PF-562,271, preclinical study in PC3M-luc-C6 local implant and metastasis xenograft models. Cancer Biol Ther 2010; 10: 38-43.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 38-43
-
-
Sun, H.1
Pisle, S.2
Gardner, E.R.3
Figg, W.D.4
-
48
-
-
78649987710
-
Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression
-
Wendt MK, Smith JA, Schiemann WP,. Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression. Oncogene 2010; 29: 6485-98.
-
(2010)
Oncogene
, vol.29
, pp. 6485-6498
-
-
Wendt, M.K.1
Smith, J.A.2
Schiemann, W.P.3
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