Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function

Journal of Cell Biology

Volumn 204, Issue 2, 2014, Pages 247-263

  Jean, Christine ^a   Chen, Xiao Lei ^a   Nam, Ju Ock ^b   Tancioni, Isabelle ^a   Uryu, Sean ^a   Lawson, Christine ^a   Ward, Kristy K ^a   Walsh, Colin T ^c   Miller, Nichol L G ^a   Ghassemian, Majid ^a   Turowski, Patric ^d   Dejana, Elisabetta ^e   Weis, Sara ^a   Cheresh, David A ^a   Schlaepfer, David D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Kyungpook National University   (South Korea)

^c Bionomics   (United States)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FOCAL ADHESION KINASE; RECOMBINANT VASCULOTROPIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; VASCULAR ENDOTHELIAL CADHERIN TYROSINE 658;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; EXTRAVASATION; GENE MUTATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG METASTASIS; MELANOMA; MOUSE; NONHUMAN; ONCOGENE SRC; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SYSTEMATIC REVIEW; TUMOR CELL;

ANIMALS; ANTIGENS, CD; CADHERINS; CELL MOVEMENT; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HEK293 CELLS; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM METASTASIS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS PP60(C-SRC); SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84892894930     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201307067     Document Type: Article

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