-
1
-
-
45849089879
-
Exploring the role of cancer stem cells in radioresistance
-
DOI 10.1038/nrc2419, PII NRC2419
-
Baumann M, Krause M, Hill R. Exploring the role of cancer stem cells in radioresistance. Nat Rev Cancer. 2008;8(7):545-554. (Pubitemid 351881850)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.7
, pp. 545-554
-
-
Baumann, M.1
Krause, M.2
Hill, R.3
-
2
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2010;144(5):646-674.
-
(2010)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
4
-
-
78650026375
-
ALK inhibition for nonsmall cell lung cancer: From discovery to therapy in record time
-
Gerber DE, Minna JD. ALK inhibition for nonsmall cell lung cancer: from discovery to therapy in record time. Cancer Cell. 2011;18(6):548-551.
-
(2011)
Cancer Cell
, vol.18
, Issue.6
, pp. 548-551
-
-
Gerber, D.E.1
Minna, J.D.2
-
5
-
-
70449509655
-
Heterogeneity of tumour response to combined radiotherapy and EGFR inhibitors: Differences between antibodies and TK inhibitors
-
Krause M, Gurtner K, Deuse Y, Baumann M. Heterogeneity of tumour response to combined radiotherapy and EGFR inhibitors: differences between antibodies and TK inhibitors. Int J Radiat Biol. 2009; 85(11):943-954.
-
(2009)
Int J Radiat Biol
, vol.85
, Issue.11
, pp. 943-954
-
-
Krause, M.1
Gurtner, K.2
Deuse, Y.3
Baumann, M.4
-
6
-
-
9244222261
-
Targeted cancer therapy
-
DOI 10.1038/nature03095
-
Sawyers C. Targeted cancer therapy. Nature. 2004; 432(7015):294-297. (Pubitemid 39551656)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 294-297
-
-
Sawyers, C.1
-
7
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
DOI 10.1056/NEJMoa053422
-
Bonner JA, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med. 2006;354(6):567-578. (Pubitemid 43209104)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.6
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Azarnia, N.4
Shin, D.M.5
Cohen, R.B.6
Jones, C.U.7
Sur, R.8
Raben, D.9
Jassem, J.10
Ove, R.11
Kies, M.S.12
Baselga, J.13
Youssoufian, H.14
Amellal, N.15
Rowinsky, E.K.16
Ang, K.K.17
-
8
-
-
0036280046
-
Integrins as novel drug targets for overcoming innate drug resistance
-
DOI 10.2174/1568009023334033
-
Damiano JS. Integrins as novel drug targets for overcoming innate drug resistance. Curr Cancer Drug Targets. 2002;2(1):37-43. (Pubitemid 34627377)
-
(2002)
Current Cancer Drug Targets
, vol.2
, Issue.1
, pp. 37-43
-
-
Damiano, J.S.1
-
9
-
-
72949119124
-
Integrins in cancer: Biological implications and therapeutic opportunities
-
Desgrosellier JS, Cheresh DA. Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer. 2010;10(1):9-22.
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.1
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
10
-
-
33845329178
-
Signalling via integrins: Implications for cell survival and anticancer strategies
-
DOI 10.1016/j.bbcan.2006.09.001, PII S0304419X06000588
-
Hehlgans S, Haase M, Cordes N. Signalling via integrins: implications for cell survival and anticancer strategies. Biochim Biophys Acta. 2007; 1775(1):163-180. (Pubitemid 44881199)
-
(2007)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1775
, Issue.1
, pp. 163-180
-
-
Hehlgans, S.1
Haase, M.2
Cordes, N.3
-
11
-
-
77953658108
-
Vascular integrins: Therapeutic and imaging targets of tumor angiogenesis
-
Ruegg C, Alghisi GC. Vascular integrins: therapeutic and imaging targets of tumor angiogenesis. Recent Results Cancer Res. 2010;180:83-101.
-
(2010)
Recent Results Cancer Res
, vol.180
, pp. 83-101
-
-
Ruegg, C.1
Alghisi, G.C.2
-
12
-
-
0036726312
-
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
-
DOI 10.1016/S1535-6108(02)00125-3
-
Weaver VM, et al. beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell. 2002; 2(3):205-216. (Pubitemid 41043976)
-
(2002)
Cancer Cell
, vol.2
, Issue.3
, pp. 205-216
-
-
Weaver, V.M.1
Lelievre, S.2
Lakins, J.N.3
Chrenek, M.A.4
Jones, J.C.R.5
Giancotti, F.6
Werb, Z.7
Bissell, M.J.8
-
13
-
-
11144322013
-
Expression of integrins and E-cadherin in squamous cell carcinomas of the head and neck
-
DOI 10.1111/j.1600-0463.2004.apm1120902.x
-
Eriksen JG, Steiniche T, Sogaard H, Overgaard J. Expression of integrins and E-cadherin in squamous cell carcinomas of the head and neck. Apmis. 2004; 112(9):560-568. (Pubitemid 40040183)
-
(2004)
APMIS
, vol.112
, Issue.9
, pp. 560-568
-
-
Eriksen, J.G.1
Steiniche, T.2
Sogaard, H.3
Overgaard, J.4
-
14
-
-
33846653542
-
1 integrin is associated with decreased survival in invasive breast cancer
-
DOI 10.1158/0008-5472.CAN-06-2768
-
Yao ES, et al. Increased beta1 integrin is associated with decreased survival in invasive breast cancer. Cancer Res. 2007;67(2):659-664. (Pubitemid 46192205)
-
(2007)
Cancer Research
, vol.67
, Issue.2
, pp. 659-664
-
-
Yao, E.S.1
Zhang, H.2
Chen, Y.-Y.3
Lee, B.4
Chew, K.5
Moore, D.6
Park, C.7
-
15
-
-
33644522372
-
New roles for integrins in squamous-cell carcinoma
-
DOI 10.1038/nrc1817, PII N1817
-
Janes SM, Watt FM. New roles for integrins in squamous-cell carcinoma. Nat Rev Cancer. 2006; 6(3):175-183. (Pubitemid 43292561)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.3
, pp. 175-183
-
-
Janes, S.M.1
Watt, F.M.2
-
16
-
-
33644778551
-
beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury
-
DOI 10.1038/sj.onc.1209164, PII 1209164
-
Cordes N, Seidler J, Durzok R, Geinitz H, Brakebusch C. beta1-integrin-mediated signaling essentially contributes to cell survival after radiation- induced genotoxic injury. Oncogene. 2006; 25(9):1378-1390. (Pubitemid 43336466)
-
(2006)
Oncogene
, vol.25
, Issue.9
, pp. 1378-1390
-
-
Cordes, N.1
Seidler, J.2
Durzok, R.3
Geinitz, H.4
Brakebusch, C.5
-
17
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
DOI 10.1016/S0092-8674(02)00971-6
-
Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell. 2002;110(6):673-687. (Pubitemid 35283958)
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 673-687
-
-
Hynes, R.O.1
-
18
-
-
66149128873
-
The tail of integrins, talin, and kindlins
-
Moser M, Legate KR, Zent R, Fassler R. The tail of integrins, talin, and kindlins. Science. 2009; 324(5929):895-899.
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 895-899
-
-
Moser, M.1
Legate, K.R.2
Zent, R.3
Fassler, R.4
-
19
-
-
67649849871
-
Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs
-
Shibue T, Weinberg RA. Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc Natl Acad Sci U S A. 2009;106(25):10290-10295.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.25
, pp. 10290-10295
-
-
Shibue, T.1
Weinberg, R.A.2
-
20
-
-
78650940402
-
The alphabeta integrin is a metastasis suppressor in mouse models and human cancer
-
Ramirez NE, et al. The alphabeta integrin is a metastasis suppressor in mouse models and human cancer. J Clin Invest. 2010;121(1):226-237.
-
(2010)
J Clin Invest
, vol.121
, Issue.1
, pp. 226-237
-
-
Ramirez, N.E.1
-
21
-
-
49249107671
-
Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts
-
Park CC, Zhang HJ, Yao ES, Park CJ, Bissell MJ. Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts. Cancer Res. 2008;68(11):4398-4405.
-
(2008)
Cancer Res
, vol.68
, Issue.11
, pp. 4398-4405
-
-
Park, C.C.1
Zhang, H.J.2
Yao, E.S.3
Park, C.J.4
Bissell, M.J.5
-
22
-
-
69249087671
-
Environment-mediated drug resistance: A major contributor to minimal residual disease
-
Meads MB, Gatenby RA, Dalton WS. Environment-mediated drug resistance: a major contributor to minimal residual disease. Nat Rev Cancer. 2009; 9(9):665-674.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.9
, pp. 665-674
-
-
Meads, M.B.1
Gatenby, R.A.2
Dalton, W.S.3
-
23
-
-
77954994889
-
PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha
-
Eke I, et al. PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha. J Clin Invest. 2010;120(7):2516-2527.
-
(2010)
J Clin Invest
, vol.120
, Issue.7
, pp. 2516-2527
-
-
Eke, I.1
-
24
-
-
61449213806
-
Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails
-
Legate KR, Fassler R. Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails. J Cell Sci. 2009;122(pt 2):187-198.
-
(2009)
J Cell Sci
, vol.122
, Issue.PART 2
, pp. 187-198
-
-
Legate, K.R.1
Fassler, R.2
-
25
-
-
0036019938
-
Antiapoptotic action of focal adhesion kinase (FAK) against ionizing radiation
-
Kasahara T, Koguchi E, Funakoshi M, Aizu-Yokota E, Sonoda Y. Antiapoptotic action of focal adhesion kinase (FAK) against ionizing radiation. Antioxid Redox Signal. 2002;4(3):491-499. (Pubitemid 34753389)
-
(2002)
Antioxidants and Redox Signaling
, vol.4
, Issue.3
, pp. 491-499
-
-
Kasahara, T.1
Koguchi, E.2
Funakoshi, M.3
Aizu-yokota, E.4
Sonoda, Y.5
-
26
-
-
48849089827
-
FERM control of FAK function: Implications for cancer therapy
-
Lim ST, Mikolon D, Stupack DG, Schlaepfer DD. FERM control of FAK function: implications for cancer therapy. Cell Cycle. 2008;7(15):2306-2314.
-
(2008)
Cell Cycle
, vol.7
, Issue.15
, pp. 2306-2314
-
-
Lim, S.T.1
Mikolon, D.2
Stupack, D.G.3
Schlaepfer, D.D.4
-
27
-
-
77951863320
-
Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis
-
Sood AK, et al. Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. J Clin Invest. 2010;120(5):1515-1523.
-
(2010)
J Clin Invest
, vol.120
, Issue.5
, pp. 1515-1523
-
-
Sood, A.K.1
-
28
-
-
77956062542
-
Expression and prognostic significance of focal adhesion kinase in hepatocellular carcinoma
-
Yuan Z, Zheng Q, Fan J, Ai KX, Chen J, Huang XY. Expression and prognostic significance of focal adhesion kinase in hepatocellular carcinoma. J Cancer Res Clin Oncol. 2010;136(10):1489-1496.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, Issue.10
, pp. 1489-1496
-
-
Yuan, Z.1
Zheng, Q.2
Fan, J.3
Ai, K.X.4
Chen, J.5
Huang, X.Y.6
-
29
-
-
0034044795
-
Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: Correlation with preinvasive and invasive phenotypes
-
Cance WG, et al. Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes. Clin Cancer Res. 2000;6(6):2417-2423. (Pubitemid 30399210)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.6
, pp. 2417-2423
-
-
Cance, W.G.1
Harris, J.E.2
Iacocca, M.V.3
Roche, E.4
Yang, X.H.5
Chang, J.6
Simkins, S.7
Xu, L.H.8
-
30
-
-
0029039421
-
Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors
-
Owens LV, et al. Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors. Cancer Res. 1995;55(13):2752-2755.
-
(1995)
Cancer Res
, vol.55
, Issue.13
, pp. 2752-2755
-
-
Owens, L.V.1
-
31
-
-
0028350859
-
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2- dependent binding of pp60src
-
Schaller MD, Hildebrand JD, Shannon JD, Fox JW, Vines RR, Parsons JT. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2- dependent binding of pp60src. Mol Cell Biol. 1994; 14(3):1680-1688.
-
(1994)
Mol Cell Biol
, vol.14
, Issue.3
, pp. 1680-1688
-
-
Schaller, M.D.1
Hildebrand, J.D.2
Shannon, J.D.3
Fox, J.W.4
Vines, R.R.5
Parsons, J.T.6
-
33
-
-
9644276865
-
Rho GTPases regulate axon growth through convergent and divergent signaling pathways
-
DOI 10.1016/j.neuron.2004.11.014, PII S0896627304007524
-
Ng J, Luo L. Rho GTPases regulate axon growth through convergent and divergent signaling pathways. Neuron. 2004;44(5):779-793. (Pubitemid 39575632)
-
(2004)
Neuron
, vol.44
, Issue.5
, pp. 779-793
-
-
Ng, J.1
Luo, L.2
-
34
-
-
0033731119
-
Integrin cytoplasmic domain-binding proteins
-
Liu S, Calderwood DA, Ginsberg MH. Integrin cytoplasmic domain-binding proteins. J Cell Sci. 2000; 113(pt 20):3563-3571.
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 20
, pp. 3563-3571
-
-
Liu, S.1
Calderwood, D.A.2
Ginsberg, M.H.3
-
35
-
-
0034911925
-
Regulation of actin filament network formation through Arp2/3 complex: Activation by a diverse array of proteins
-
DOI 10.1146/annurev.biochem.70.1.649
-
Higgs HN, Pollard TD. Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins. Annu Rev Biochem. 2001;70:649-676. (Pubitemid 32662221)
-
(2001)
Annual Review of Biochemistry
, vol.70
, pp. 649-676
-
-
Higgs, H.N.1
Pollard, T.D.2
-
36
-
-
0035475450
-
Cortactin: Coupling membrane dynamics to cortical actin assembly
-
DOI 10.1038/sj.onc.1204783
-
Weed SA, Parsons JT. Cortactin: coupling membrane dynamics to cortical actin assembly. Oncogene. 2001;20(44):6418-6434. (Pubitemid 32977848)
-
(2001)
Oncogene
, vol.20
, Issue.44 REV. ISS. 5
, pp. 6418-6434
-
-
Weed, S.A.1
Parsons, J.T.2
-
37
-
-
34249320529
-
Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia
-
DOI 10.1158/0008-5472.CAN-06-3928
-
Clark ES, Whigham AS, Yarbrough WG, Weaver AM. Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. Cancer Res. 2007; 67(9):4227-4235. (Pubitemid 46815069)
-
(2007)
Cancer Research
, vol.67
, Issue.9
, pp. 4227-4235
-
-
Clark, E.S.1
Whigham, A.S.2
Yarbrough, W.G.3
Weaver, A.M.4
-
38
-
-
2442676727
-
Cytoplasmic p120ctn regulates the invasive phenotypes of E-cadherin-deficient breast cancer
-
Shibata T, Kokubu A, Sekine S, Kanai Y, Hirohashi S. Cytoplasmic p120ctn regulates the invasive phenotypes of E-cadherin-deficient breast cancer. Am J Pathol. 2004;164(6):2269-2278. (Pubitemid 38669372)
-
(2004)
American Journal of Pathology
, vol.164
, Issue.6
, pp. 2269-2278
-
-
Shibata, T.1
Kokubu, A.2
Sekine, S.3
Kanai, Y.4
Hirohashi, S.5
-
39
-
-
33846974037
-
Transmitting on actin: Synaptic control of dendritic architecture
-
Schubert V, Dotti CG. Transmitting on actin: synaptic control of dendritic architecture. J Cell Sci. 2007; 120(pt 2):205-212.
-
(2007)
J Cell Sci
, vol.120
, Issue.PART 2
, pp. 205-212
-
-
Schubert, V.1
Dotti, C.G.2
-
40
-
-
33947140891
-
Dissecting the functional domain requirements of cortactin in invadopodia formation
-
DOI 10.1016/j.ejcb.2007.01.003, PII S0171933507000155
-
Webb BA, Jia L, Eves R, Mak AS. Dissecting the functional domain requirements of cortactin in invadopodia formation. Eur J Cell Biol. 2007; 86(4):189-206. (Pubitemid 46404601)
-
(2007)
European Journal of Cell Biology
, vol.86
, Issue.4
, pp. 189-206
-
-
Webb, B.A.1
Jia, L.2
Eves, R.3
Mak, A.S.4
-
41
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
Ridley AJ, Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell. 1992;70(3):389-399.
-
(1992)
Cell
, vol.70
, Issue.3
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
42
-
-
34548316989
-
Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex
-
DOI 10.1038/ncb1626, PII NCB1626
-
Serrels B, et al. Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex. Nat Cell Biol. 2007;9(9):1046-1056. (Pubitemid 47338144)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.9
, pp. 1046-1056
-
-
Serrels, B.1
Serrels, A.2
Brunton, V.G.3
Holt, M.4
McLean, G.W.5
Gray, C.H.6
Jones, G.E.7
Frame, M.C.8
-
43
-
-
33747781419
-
Digital quantification using amplified single-molecule detection
-
DOI 10.1038/nmeth916, PII NMETH916
-
Jarvius J, et al. Digital quantification using amplified single-molecule detection. Nat Methods. 2006; 3(9):725-727. (Pubitemid 44275741)
-
(2006)
Nature Methods
, vol.3
, Issue.9
, pp. 725-727
-
-
Jarvius, J.1
Melin, J.2
Goransson, J.3
Stenberg, J.4
Fredriksson, S.5
Gonzalez-Rey, C.6
Bertilsson, S.7
Nilsson, M.8
-
44
-
-
0036682924
-
Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'
-
DOI 10.1042/BJ20020065
-
Gabarra-Niecko V, Keely PJ, Schaller MD. Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'. Biochem J. 2002; 365(pt 3):591-603. (Pubitemid 34864441)
-
(2002)
Biochemical Journal
, vol.365
, Issue.3
, pp. 591-603
-
-
Gabarra-Niecko, V.1
Keely, P.J.2
Schaller, M.D.3
-
45
-
-
2542435885
-
BPGAP1 interacts with cortactin and facilitates its translocation to cell periphery for enhanced cell migration
-
DOI 10.1091/mbc.E04-02-0141
-
Lua BL, Low BC. BPGAP1 interacts with cortactin and facilitates its translocation to cell periphery for enhanced cell migration. Mol Biol Cell. 2004; 15(6):2873-2883. (Pubitemid 38691875)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.6
, pp. 2873-2883
-
-
Lua, B.L.1
Low, B.C.2
-
46
-
-
77958502225
-
The FERM domain: Organizing the structure and function of FAK
-
Frame MC, Patel H, Serrels B, Lietha D, Eck MJ. The FERM domain: organizing the structure and function of FAK. Nat Rev Mol Cell Biol. 2010;11(11):802-814.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, Issue.11
, pp. 802-814
-
-
Frame, M.C.1
Patel, H.2
Serrels, B.3
Lietha, D.4
Eck, M.J.5
-
47
-
-
36849053853
-
beta1 integrin as a molecular therapeutic target
-
DOI 10.1080/09553000701639694, PII 787788695
-
Cordes N, Park CC. beta1 integrin as a molecular therapeutic target. Int J Radiat Biol. 2007; 83(11-12):753-760. (Pubitemid 350219108)
-
(2007)
International Journal of Radiation Biology
, vol.83
, Issue.11-12
, pp. 753-760
-
-
Cordes, N.1
Park, C.C.2
-
48
-
-
70749103751
-
Tissue-penetrating delivery of compounds and nanoparticles into tumors
-
Sugahara KN, et al. Tissue-penetrating delivery of compounds and nanoparticles into tumors. Cancer Cell. 2009;16(6):510-520.
-
(2009)
Cancer Cell
, vol.16
, Issue.6
, pp. 510-520
-
-
Sugahara, K.N.1
-
49
-
-
67649528138
-
Collective cell migration in morphogenesis, regeneration and cancer
-
Friedl P, Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol. 2009;10(7):445-457.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.7
, pp. 445-457
-
-
Friedl, P.1
Gilmour, D.2
-
50
-
-
79955469358
-
5?-Nitro-indirubinoxime, an indirubin derivative, suppresses metastatic ability of human head and neck cancer cells through the inhibition of Integrin beta1/FAK/Akt signaling
-
Kim SA, Kwon SM, Kim JA, Kang KW, Yoon JH, Ahn SG. 5?-Nitro- indirubinoxime, an indirubin derivative, suppresses metastatic ability of human head and neck cancer cells through the inhibition of Integrin beta1/FAK/Akt signaling. Cancer Lett. 2011; 306(2):197-204.
-
(2011)
Cancer Lett
, vol.306
, Issue.2
, pp. 197-204
-
-
Kim, S.A.1
Kwon, S.M.2
Kim, J.A.3
Kang, K.W.4
Yoon, J.H.5
Ahn, S.G.6
-
51
-
-
79952741178
-
Cilengitide: The first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation
-
Mas-Moruno C, Rechenmacher F, Kessler H. Cilengitide: the first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation. Anticancer Agents Med Chem. 2010;10(10):753-768.
-
(2010)
Anticancer Agents Med Chem
, vol.10
, Issue.10
, pp. 753-768
-
-
Mas-Moruno, C.1
Rechenmacher, F.2
Kessler, H.3
-
52
-
-
59449094255
-
Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: A phase I, pharmacokinetic, and biological correlative study
-
Ricart AD, et al. Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: a phase I, pharmacokinetic, and biological correlative study. Clin Cancer Res. 2008;14(23):7924-7929.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.23
, pp. 7924-7929
-
-
Ricart, A.D.1
-
53
-
-
35348995145
-
Ligand bound beta1 integrins inhibit procaspase-8 for mediating cell adhesion-mediated drug and radiation resistance in human leukemia cells
-
Estrugo D, Fischer A, Hess F, Scherthan H, Belka C, Cordes N. Ligand bound beta1 integrins inhibit procaspase-8 for mediating cell adhesion-mediated drug and radiation resistance in human leukemia cells. PLoS One. 2007;2(3):e269.
-
(2007)
PLoS One
, vol.2
, Issue.3
-
-
Estrugo, D.1
Fischer, A.2
Hess, F.3
Scherthan, H.4
Belka, C.5
Cordes, N.6
-
55
-
-
80053320001
-
β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells
-
Morello V, et al. β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells. Oncogene. 2011;30(39):4087-4096.
-
(2011)
Oncogene
, vol.30
, Issue.39
, pp. 4087-4096
-
-
Morello, V.1
-
56
-
-
0024335963
-
Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression
-
Werb Z, Tremble PM, Behrendtsen O, Crowley E, Damsky CH. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J Cell Biol. 1989; 109(2):877-889. (Pubitemid 19197045)
-
(1989)
Journal of Cell Biology
, vol.109
, Issue.2
, pp. 877-889
-
-
Werb, Z.1
Tremble, P.M.2
Behrendtsen, O.3
Crowley, E.4
Damsky, C.H.5
-
57
-
-
4143144444
-
B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of Polo-like kinase 1
-
DOI 10.1074/jbc.M403264200
-
Zhang H, Shi X, Paddon H, Hampong M, Dai W, Pelech S. B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1. J Biol Chem. 2004;279(34):35726-35734. (Pubitemid 39100577)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.34
, pp. 35726-35734
-
-
Zhang, H.1
Shi, X.2
Paddon, H.3
Hampong, M.4
Dai, W.5
Pelech, S.6
|