Ganglioside GD1a suppresses LPS-induced pro-inflammatory cytokines in RAW264.7 macrophages by reducing MAPKs and NF-κB signaling pathways through TLR4

International Immunopharmacology

Volumn 28, Issue 1, 2015, Pages 136-145

  Wang, Yiren ^a   Cui, Yuting ^a   Cao, Fayang ^a   Qin, Yiyang ^a   Li, Wenjing ^a   Zhang, Jinghai ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Anti inflammation; Ganglioside GD1a; Mitogen activated protein kinases; Nuclear factor kappa B; Toll like receptor 4

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; GANGLIOSIDE GD 1A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; GANGLIOSIDE; GANGLIOSIDE, GD1A; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; NOS2 PROTEIN, MOUSE; PROSTAGLANDIN E2; PTGS2 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; DRUG EFFECT; DRUG INHIBITION; ENZYME DEGRADATION; GENE TRANSLOCATION; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL SURVIVAL; DRUG EFFECTS; METABOLISM; MOUSE; PHOSPHORYLATION; RAW 264.7 CELL LINE; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL SURVIVAL; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; GANGLIOSIDES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; RAW 264.7 CELLS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84930942316     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.05.044     Document Type: Article

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