GM1 and GD1a gangliosides modulate toxic and inflammatory effects of E. coli lipopolysaccharide by preventing TLR4 translocation into lipid rafts

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1851, Issue 3, 2015, Pages 239-247

  Nikolaeva, Svetlana ^a   Bayunova, Lubov ^a   Sokolova, Tatyana ^a   Vlasova, Yulia ^a   Bachteeva, Vera ^a   Avrova, Natalia ^a   Parnova, Rimma ^a  

^a SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

Frog urinary bladder epithelial cells; Ganglioside; Lipid raft; Lipopolysaccharide; PC12 cells; TLR4

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GANGLIOSIDE GD 1A; GANGLIOSIDE GM1; INDUCIBLE NITRIC OXIDE SYNTHASE; K 252A; METHYL BETA CYCLODEXTRIN; PROSTAGLANDIN E2; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 4; BETA CYCLODEXTRIN DERIVATIVE; GANGLIOSIDE GD1ALPHA; LIPOPOLYSACCHARIDE; METHYL-BETA-CYCLODEXTRIN; NITRIC OXIDE; NOS2 PROTEIN, RAT; TLR4 PROTEIN, RAT;

ANIMAL CELL; ARTICLE; BLADDER; CELL FRACTIONATION; CELL MEMBRANE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DEATH; ENZYME ACTIVITY; EPITHELIUM CELL; EXPERIMENTAL DISEASE; IMMUNOBLOTTING; IN VITRO STUDY; LIPID RAFT; LIPOPOLYSACCHARIDE INDUCED INFLAMMATION; LIPOPOLYSACCHARIDE INDUCED TOXICITY; MALE; NONHUMAN; PC12 CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BOVINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PRIMARY CELL CULTURE; PROTEIN TRANSPORT; RANA TEMPORARIA; RAT;

ANURA; ESCHERICHIA COLI;

ANIMALS; BETA-CYCLODEXTRINS; CATTLE; CELL SURVIVAL; DINOPROSTONE; EPITHELIAL CELLS; ESCHERICHIA COLI; G(M1) GANGLIOSIDE; GENE EXPRESSION REGULATION; LIPOPOLYSACCHARIDES; MALE; MEMBRANE MICRODOMAINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PC12 CELLS; PRIMARY CELL CULTURE; PROTEIN TRANSPORT; RANA TEMPORARIA; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; URINARY BLADDER;

EID: 84920733339     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.12.004     Document Type: Article

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