Anti-inflammatory mechanism of exogenous C2 ceramide in lipopolysaccharide-stimulated microglia

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1831, Issue 6, 2013, Pages 1016-1026

  Jung, Ji Sun ^a   Shin, Kyong Oh ^b   Lee, Yong Moon ^b   Shin, Jin A ^a   Park, Eun Mi ^a   Jeong, Jinju ^c   Kim, Dong Hyun ^c   Choi, Ji Woong ^d   Kim, Hee Sun ^a  

^a Ewha Womans University School of Medicine   (South Korea)

^b Chungbuk National University   (South Korea)

^c Kyung Hee University   (South Korea)

^d Gachon University College of Medicine   (South Korea)

Author keywords

C2 ceramide; Microglia; Molecular mechanism; Neuroinflammation; Short chain ceramide; TLR4

Indexed keywords

ANTIINFLAMMATORY AGENT; C2 CERAMIDE; C6 CERAMIDE; C8 CERAMIDE; C8 CERAMIDE 1 PHOSPHATE; CERAMIDE 1 PHOSPHATE; CERAMIDE DERIVATIVE; CYTOKINE; HEMEOXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; JANUS KINASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; OXYGENASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SHORT CHAIN CERAMIDE; SPHINGOLIPID; STAT PROTEIN; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL GROWTH; CELL MEMBRANE; CELL PERMEABILIZATION; CELL STIMULATION; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENCEPHALITIS; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; MALE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; BLOTTING, WESTERN; BRAIN; CELL PROLIFERATION; CELLS, CULTURED; CERAMIDES; CYTOKINES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; LIPOPOLYSACCHARIDES; LUCIFERASES; MICE; MICROGLIA; NITRITES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEPSIS; SIGNAL TRANSDUCTION;

MUS; RATTUS;

EID: 84876921937     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2013.01.020     Document Type: Article

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