Protection of intestinal occludin tight junction protein by dietary gangliosides in lipopolysaccharide-induced acute inflammation

Journal of Pediatric Gastroenterology and Nutrition

Volumn 50, Issue 3, 2010, Pages 321-328

  Park, Eek J ^a   Thomson, Alan B R ^a   Clandinin, Michael T ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Gangliosides; IL 10; Inflammation; Nitric oxide; Tight junction

Indexed keywords

CASEIN; CELLULOSE; CHOLESTEROL; CHOLINE; GANGLIOSIDE; GLUCOSE; INDUCIBLE NITRIC OXIDE SYNTHASE; INOSITOL; INTERLEUKIN 10; INTERLEUKIN 1BETA; LEUKOTRIENE B4; LIPOPOLYSACCHARIDE; METHIONINE; MINERAL; NITRIC OXIDE; OCCLUDIN; PHOSPHOLIPID; PROSTAGLANDIN E2; SODIUM CHLORIDE; STARCH; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VITAMIN MIXTURE;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIET; DIET THERAPY; ENTERITIS; FOOD COMPOSITION; IN VIVO STUDY; INTESTINE MUCOSA; INTESTINE MUCOSA PERMEABILITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; TIGHT JUNCTION; TREATMENT DURATION;

ACUTE DISEASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL MEMBRANE PERMEABILITY; DIETARY FATS; GANGLIOSIDES; INFLAMMATION; INTERLEUKIN-10; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; LIPOPOLYSACCHARIDES; MALE; MEMBRANE PROTEINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY; TIGHT JUNCTIONS;

ANIMALIA; RATTUS;

EID: 77649313855     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e3181ae2ba0     Document Type: Article

References (50)

1. Stevenson BR. Understanding tight junction clinical physiology at the molecular level. J Clin Invest 1999;104:3-4.
2. Farquhar MG, Palade GE. Junctional complexes in various epithelia. J Cell Biol 1963;17:375-412.
3. Muza-Moons MM, Schneeberger EE, Hecht GA. Enteropathogenic Escherichia coli infection leads to appearance of aberrant tight junctions strands in the lateral membrane of intestinal epithelial cells. Cell Microbiol 2004;6:783-793
4. Han X, Fink MP, Delude RL. Proinflammatory cytokines cause NO-dependent and -independent changes in expression and localization of tight junction proteins in intestinal epithelial cells. Shock 2003;19:229-237
5. Gonzalez-Mariscal L, Betanzos A, Nava P, et al. Tight junction proteins. Prog Biophys Mol Biol 2003;81:1-44.
6. Tsukita S, Furuse M, Itoh M. Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol 2001;2:285-293
7. Wittchen ES, Haskins J, Stevenson BR. Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3. J Biol Chem 1999;274: 35179-35185
8. Harhaj NS, Antonetti DA. Regulation of tight junctions and loss of barrier function in pathophysiology. Int J Biochem Cell Biol 2004;36:1206-1237
9. Neu J, Reverte CM, Mackey AD, et al. Changes in intestinal morphology and permeability in the biobreeding rat before the onset of type 1 diabetes. J Pediatr Gastroenterol Nutr 2005;40:589-595
10. Leroy A, Lauwaet T, De Bruyne G, et al. Entamoeba histolytica disturbs the tight junction complex in human enteric T84 cell layers. FASEB J 2000;14:1139-1146
11. Sappington PL, Han X, Yang R, et al. Ethyl pyruvate ameliorates intestinal epithelial barrier dysfunction in endotoxemic mice and immunostimulated caco-2 enterocytic monolayers. J Pharmacol Exp Ther 2003;304:464-476
12. Han X, Fink MP, Yang R, et al. Increased iNOS activity is essential for intestinal epithelial tight junction dysfunction in endotoxemic mice. Shock 2004;21:261-270
13. Byrne MC, Ledeen RW, Roisen FJ, et al. Ganglioside-induced neuritogenesis: verification that gangliosides are the active agents, and comparison of molecular species. J Neurochem 1983; 41:1214-1222
14. De Maria R, Lenti L, Malisan F, et al. Requirement for GD3 ganglioside in CD95- and ceramide-induced apoptosis. Science 1997;277:1652-1655
15. Ortaldo JR, Mason AT, Longo DL, et al. T cell activation via the disialoganglioside GD3: analysis of signal transduction. J Leukoc Biol 1996;60:533-539
16. Rolsma MD, Kuhlenschmidt TB, Gelberg HB, et al. Structure and function of a ganglioside receptor for porcine rotavirus. J Virol 1998;72:9079-9091
17. Laegreid A, Kolsto Otnaess AB. Trace amounts of ganglioside GM1 in human milk inhibit enterotoxins from Vibrio cholerae and Escherichia coli. Life Sci 1987;40:55-62.
18. Welte K, Miller G, Chapman PB, et al. Stimulation of T lymphocyte proliferation by monoclonal antibodies against GD3 ganglioside. J Immunol 1987;139:1763-1771
19. Correa SG, Bianco ID, Riera CM, et al. Anti-inflammatory effect of gangliosides in the rat hindpaw edema test. Eur J Pharmacol 1991; 199:93-98
20. Gomez-Nicola D, Doncel-Perez E, Nieto-Sampedro M. Regulation by GD3 of the proinflammatory response of microglia mediated by interleukin-15. J Neurosci Res 2006;83:754-762
21. Ziegler-Heitbrock HW, Kafferlein E, Haas JG, et al. Gangliosides suppress tumor necrosis factor production in human monocytes. J Immunol 1992;148:1753-1758
22. Colarow L, Turini M, Teneberg S, et al. Characterization and biological activity of gangliosides in buffalo milk. Biochim Biophys Acta 2003; 1631:94-106.
23. Brown DA, London E. Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 1998;14:111-136
24. Hakomori S, Handa K. Variation in components and function of glycosignaling domain, and factors affecting them. Glycobiology 2000;10:1086-1087
25. Park EJ, Suh M, Thomson B, et al. Dietary ganglioside decreases cholesterol content, caveolin expression and inflammatory mediators in rat intestinal microdomains. Glycobiology 2005;15:935-942
26. Park EJ, Thomson B, Ma DWL, et al. Dietary ganglioside inhibits acute inflammatory signals in intestinal mucosa and blood induced by systemic inflammation of Escherichia coli lipopolysaccharide. Shock 2007;28:112-117
27. Raychaudhuri B, Fisher CJ, Farver CF, et al. Interleukin 10 (IL-10)- mediated inhibition of inflammatory cytokine production by human alveolar macrophages. Cytokine 2000;12:1348-1355
28. Nemoto Y, Otsuka T, Niiro H, et al. Differential effects of interleukin-4 and interleukin-10 on nitric oxide production by murine macrophages. Inflamm Res 1999;48:643-650
29. Oswald IP, Wynn TA, Sher A, et al. Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor alpha required as a costimulatory factor for interferon gamma-induced activation. Proc Natl Acad Sci U S A 1992;89:8676-8680
30. Clandinin MT, Yamashiro S. Effects of methionine supplementation on the incidence of dietary fat induced myocardial lesions in the rat. J Nutr 1980;110:1197-1203
31. Jumpsen J, Lien EL, Goh YK, et al. Small changes of dietary (n-6) and (n-3)/fatty acid content ration alter phosphatidylethanolamine and phosphatidylcholine fatty acid composition during development of neuronal and glial cells in rats. J Nutr 1997;127:724-731
32. Schmidt RJ, Baylis C. Total nitric oxide production is low in patients with chronic renal disease. Kidney Int 2000;58:1261-1266
33. Bartholomew B. A rapid method for the assay of nitrate in urine using the nitrate reductase enzyme of Escherichia coli. Food Chem Toxicol 1984;22:541-543
34. Rosengren S, Firestein GS, Boyle DL. Measurement of inflammatory biomarkers in synovial tissue extracts by enzyme-linked immunosorbent assay. Clin Diagn Lab Immunol 2003;10:1002-1010
35. Inoue G. Effect of interleukin-10 (IL-10) on experimental LPS-induced acute lung injury. J Infect Chemother 2000;6:51-60.
36. Wink DA, Hanbauer I, Laval F, et al. Nitric oxide protects against the cytotoxic effects of reactive oxygen species. Ann N Y Acad Sci 1994;17:265-278
37. Kim SJ, Ha MS, Choi EY, et al. Nitric oxide production and inducible nitric oxide synthase expression induced by Prevotella nigrescens lipopolysaccharide. FEMS Immunol Med Microbiol 2005;43:51-58
38. Uribe RM, Lee S, Rivier C. Endotoxin stimulates nitric oxide production in the paraventricular nucleus of the hypothalamus through nitric oxide synthase I: correlation with hypothalamic-pituitary-adrenal axis activation. Endocrinology 1999;140:5971-5981
39. Salzman AL, Menconi MJ, Unno N, et al. Nitric oxide dilates tight junctions and depletes ATP in cultured Caco-2BBe intestinal epithelial monolayers. Am J Physiol 1995;268:G361-73.
40. Unno N,Wang H, Menconi MJ, et al. Inhibition of inducible nitric oxide synthase ameliorates endotoxin-induced gut mucosal barrier dysfunction in rats. Gastroenterology 1997;113:1246-1257
41. Chavez AM, Menconi MJ, Hodin RA, et al. Cytokine-induced intestinal epithelial hyperpermeability: role of nitric oxide. Crit Care Med 1999;27:2246-2251
42. Berg DJ, Zhang J, Lauricella DM, et al. Il-10 is a central regulator of cyclooxygenase-2 expression and prostaglandin production. J Immunol 2001;166:2674-2680 (Pubitemid 32173507)
43. Sun X, Yang H, Nose K, et al. Decline in intestinal mucosal IL-10 expression and decreased intestinal barrier function in a mouse model of total parenteral nutrition. Am J Physiol Gastrointest Liver Physiol 2008;294:G139-47.
44. Inokuchi J, Kabayama K, Uemura S, et al. Glycosphingolipids govern gene expression. Glycoconj J 2004;20:169-178
45. Samuel BU, Mohandas N, Harrison T, et al. The role of cholesterol and glycosylphosphatidylinositol-anchored proteins of erythrocyte rafts in regulating raft protein content and malarial infection. J Biol Chem 2001;276:29319-29322
46. Wolf AA, Fujinaga Y, Lencer WI. Uncoupling of the cholera toxin- G(M1) ganglioside receptor complex from endocytosis, retrograde Golgi trafficking, and downstream signal transduction by depletion of membrane cholesterol. J Biol Chem 2002;277:16249-16256
47. Veluthakal R, Chvyrkova I, Tannous M, et al. Essential role for membrane lipid rafts in interleukin-1beta-induced nitric oxide release from insulin-secreting cells: potential regulation by caveolin-1+. Diabetes 2005;54:2576-2585
48. Zhang S, Jin HJ, Zhou JF, et al. Disruption of lipid rafts impairs the production of nitric oxide in lipopolysaccharide-stimulated murine RAW264.7 macrophages. Res Chem Intermediates 2006;32:847-856
49. Imaizumi K, Nagatomi A, Sato M, et al. Cholesterol metabolism in ExHC (exogenous hypercholesterolemic) rats. Biochim Biophys Acta 1992;1123:101-109
50. Forstner GG, Wherrett JR. Plasma membrane and mucosal glycosphingolipids in the rat intestine. Biochim Biophys Acta 1973;306:446-459