Catecholamine-induced interleukin-10 release: A key mechanism in systemic immunodepression after brain injury

Critical Care

Volumn 3, Issue 6, 1999, Pages

  Woiciechowsky, Christian ^a   Schöning, Britta ^a   Lanksch, Wolfgang R ^a   Volk, Hans Dieter ^a   Döcke, Wolf Dietrich ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Brain injury; Critical illness; Immunodepression; Infection; Inflammation; Prognosis

Indexed keywords

CATECHOLAMINE; INTERLEUKIN 10;

ADRENERGIC STIMULATION; ARTICLE; BRAIN INJURY; CYTOKINE RELEASE; HUMAN; IMMUNE DEFICIENCY; IMMUNOREACTIVITY; INTRACRANIAL PRESSURE; PATHOGENESIS; PRIORITY JOURNAL;

EID: 1642617750     PISSN: 13648535     EISSN: None     Source Type: Journal    
DOI: 10.1186/cc375     Document Type: Article

References (61)

1. Rodriguez JL, Gibbons KJ, Bitzer LG, et al: Pneumonia: incidence, risk factors, and outcome in injured patients. J Trauma 1991, 31: 907-912.
2. Hsieh AH, Bishop MJ, Kubilis PS, et al: Pneumonia following closed head injury. Am Rev Respir Dis 1992, 146:290-294.
3. Piek J, Chesnut RM, Marshall LF, et al: Extracranial complications of severe head injury. J Neurosurg 1992, 77:901-907.
4. Beamer NB, Coull BM, Clark WM, et al: Interleukin-6 and interleukin-1 receptor antagonist in acute stroke. Ann Neurol 1995, 37: 800-805.
5. Fassbender K, Rossol S, Kammer T, et al: Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease. J Neurol Sci 1994, 122:135-139.
6. Kossmann T, Hans VH, Imhof HG, et al: Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries. Shock 1995, 4:311-317.
7. Ott L, McClain CJ, Gillespie M, et al: Cytokines and metabolic dysfunction after severe head injury. J Neurotrauma 1994, 11:447-472.
8. Woiciechowsky C, Asadullah K, Nestler D, et al: Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury. Nature Med 1998, 4:808-813.
9. Asadullah K, Woiciechowsky C, Döcke WD, et al: Immunodepression following neurosurgical procedures. Crit Care Med 1995, 23: 1976-1983.
10. Asadullah K, Woiciechowsky C, Döcke WD, et al: Very low monocytic HLA-DR expression indicates high risk of infection: immunomonitoring for patients after neurosurgery and patients during high dose steroid therapy. Eur J Emerg Med 1996, 2:184-190.
11. van-der PT, Jansen J, Endert E, et al: Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin 6 production in human whole blood. Infect Immun 1994, 62: 2046-2050.
12. van der Poll T, Coyle SM, Barbosa K, et al: Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia. J Clin Invest 1996, 97:713-719.
13. Kapcala LP, Chautard T, Eskay RL: The protective role of the hypothalamic-pituitary-adrenal axis against lethality produced by immune, infectious, and inflammatory stress. Ann N Y Acad Sci 1995, 771:419-437.
14. Lennard TW, Shenton BK, Borzotta A, et al: The influence of surgical operations on components of the human immune system. Br J Surg 1985, 72:771-776.
15. Guillou PJ: Biological variation in the development of sepsis after surgery or trauma. Lancet 1993, 342:217-220.
16. Miller Graziano CL, Szabo G, Kodys K, et al: Aberrations in post-trauma monocyte (MO) subpopulation: role in septic shock syndrome. J Trauma 1990, 30:S86-S96.
17. Gibbons RA, Martinez OM, Lim RC, et al: Reduction in HLA-DR, HLA-DQ and HLA-DP expression by Leu-M3+ cells from the peripheral blood of patients with thermal injury. Clin Exp Immunol 1989, 75:371-375.
18. Cheadle WG, Hershman MJ, Wellhausen SR, et al: HLA-DR antigen expression on peripheral blood monocytes correlates with surgical infection. Am J Surg 1991, 161:639-645.
19. Fiorentino DF, Zlotnik A, Mosmann TR, et al: IL-10 inhibits cytokine production by activated macrophages. J Immunol 1991, 147:3815-3822.
20. Mosmann TR. Interleukin-10. In: The Cytokine Handbook. Edited by Thomson A. London: Academic Press, 1994:223-237.
21. Döcke WD, Jacobi CA, Stösslein R, et al: Rapid IL-10 release after major surgery may contribute to post-operative immunodepression [abstract]. Immunobiology 1996, 196:59.
22. Sherry RM, Cue JI, Goddard JK, et al: Interleukin-10 is associated with the development of sepsis in trauma patients. J Trauma 1996, 40:613-616.
23. Schöning B, Elepfandt P, Lanksch WR, et al: Continuous infusion of proinflammatory cytokines into the brain to study brain cytokine induced local and systemic immune effects. Brain Res Brain Res Protoc 1999, 1:217-222.
24. Celada A, Nathan C: Macrophage activation revisited. Immunol Today 1994, 15:100-102.
25. Döcke WD, Randow F, Syrbe U, et al: Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nature Med 1997, 3:678-681.
26. Hoch RC, Rodriguez R, Manning T, et al: Effects of accidental trauma on cytokine and endotoxin production [see comments]. Crit Care Med 1993, 21:839-845.
27. Livingston DH, Appel SH, Wellhausen SR, et al: Depressed interferon gamma production and monocyte HLA-DR expression after severe injury. Arch Surg 1988, 123:1309-1312.
28. Ottaviani E, Franceschi C: The invertebrate phagocytic immunocyte: clues to a common evolution of immune and neuroendocrine systems, Immunol Today 1997, 18:169-174.
29. Deuel TF, Kawahara RS, Mustoe TA, et al: Growth factors and wound healing: platelet-derived growth factor as a model cytokine. Annu Rev Med 1991, 42:567-584.
30. Unanue ER. Makrophages, antigen-presentig cells, and the phenomena of antigen handling and presentation. In: Fundamental Immunology. Edited by Paul WE. New York: Raven Press, 1993:111-138.
31. Trinchieri G: Proinflammatory and immunoregulatory functions of interleukin-12. Int Rev Immunol 1998, 16:365-396.
32. Trinchieri G: Immunobiology of interleukin-12. Immunol Res 1998, 17:269-278.
33. Howard M, O'Garra A: Biological properties of interleukin 10. Immunol Today 1992, 13:198-200.
34. Mathiesen T, Edner G, Ulfarsson E, et al: Cerebrospinal fluid interleukin-1 receptor antagonist and tumor necrosis factor-alpha following subarachnoid hemorrhage. J Neurosurg 1997, 87:215-220.
35. Bogdan C, Paik J, Vodovotz Y, et al: Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10. J Biol Chem 1992, 267: 23301-23308.
36. Pretolani M, Goldman M: IL-10: a potential therapy for allergic inflammation? Immunol Today 1997, 18:277-280.
37. Volk HD, Reinke P, Krausch D, et al: Monocyte deactivation: rationale for a new therapeutic strategy in sepsis. Intens Care Med 1996, 22:474-481.
38. Döcke WD, Platzer C, Syrbe U, et al: Monocytic deactivation in fatal septic disease: role of tumor necrosis factor-alpha and interleukin-10. In MOF, MODS and SIRS. Basic Mechanisms in Inflammation and Tissue Injury. Edited by Faist E, Baue A, Schildberg F. Lengerich: Pabst Science Publishers, 1996:162-168.
39. Volk HD, Thieme M, Ruppe U, et al: Alterations in function and phenotype of monocytes from patients with septic disease: predictive value and new therapeutic strategies. In: Host Defense Dysfunction in Trauma, Shock and Sepsis. Edited by Faist E, Meakins JL, Schildberg F. Berlin, Heidelberg: Springer, 1993:365-371.
40. de-Waal MR, Abrams J, Bennett B, et al: Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991, 174:1209-1220.
41. Cavaillon JM: Cytokines and macrophages. Biomed Pharmacother 1994, 48:445-453.
42. Platzer C, Meisel C, Vogt K, et al: Up-regulation of monocytic IL-10 by tumor necrosis factor-alpha and cAMP elevating drugs. Int Immunol 1995, 7:517-523.
43. Madden KS, Sanders VM, Felten DL: Catecholamine influences and sympathetic neural modulation of immune responsiveness. Annu Rev Pharmacol Toxicol 1995, 35:417-448.
44. Meisel C, Vogt K, Platzer C, et al: Differential regulation of monocytic tumor necrosis factor-alpha and interleukin-10 expression. Eur J Immunol 1996, 26:1580-1586.
45. Severn A, Rapson NT, Hunter CA, et al: Regulation of tumor necrosis factor production by adrenaline and beta-adrenergic agonists. J Immunol 1992, 148:3441-3445.
46. Croiset G, Heijnen CJ, van der Wal WE, et al: A role for the autonomic nervous system in modulating the immune response during mild emotional stimuli. Life Sci 1990, 46:419-425.
47. Terao A, Oikawa M, Saito M: Tissue-specific increase in norepinephrine turnover by central interleukin-1, but not by interleukin-6, in rats. Am J Physiol 1994, 266:R400-R404.
48. Ichijo T, Katafuchi T, Hori T: Central interleukin-1 beta enhances splenic sympathetic nerve activity in rats. Brain Res Bull 1994, 34: 547-553.
49. Shimizu N, Hori T, Nakane H: An interleukin-1 beta-induced noradrenaline release in the spleen is mediated by brain corticotropin-releasing factor: an in vivo microdialysis study in conscious rats. Brain Behav Immun 1994, 8:14-23.
50. Woiciechowsky C, Schöning B, Daberkow N, et al: Brain-IL-1β induces local inflammation but systemic anti-inflammatory response through stimulation of both hypothalamic-pituitary-adrenal axis and sympathetic nervous system. Brain Res 1999, 816:563-571.
51. Woiciechowsky C, Schöning B, Daberkow N, et al: Brain IL-1β increases neutrophil and decreases lymphocyte counts through stimulation of neuroimmune pathways. Neurobiology Dis 1999, 6: 200-208.
52. Woiciechowsky C, Asadullah K, Nestler D, et al: Different release of cytokines into the cerebrospinal fluid following surgery for intra- and extra-axial brain tumours. Acta Neurochir Wien 1997, 139:619-624.
53. Woiciechowsky C, Asadullah K, Döcke WD, et al: Immunodepression following neurosurgical procedures resulting from activation of the neuroendocrine system [abstract]. Zentralbl Neurochir 1997, 58:86.
54. Fiorentino DF, Zlotnik A, Vieira P, et al: IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol 1991, 146:3444-3451.
55. Fisher SA, Absher M: Norepinephrine and ANG II stimulate secretion of TGF-beta by neonatal rat cardiac fibroblasts in vitro. Am J Physiol 1995, 268:C910-C917.
56. Sigurdsson A, Held P, Swedberg K: Short- and long-term neurohormonal activation following acute myocardial infarction. Am Heart J 1993, 126:1068-1076.
57. Bohm H, Laimer H, Douglas T: Plasma ANP, noradrenaline, lactate concentrations during standardized ergometric stress in post-infarct patients. Evaluation of myocardial stress function with reference to limits of exercise therapy [in German]. Z Kardiol 1991, 80 (suppl 8):85.
58. Blandini F, Martignoni E, Sances E, et al: Combined response of plasma and platelet catecholamines to different types of short-term stress. Life Sci 1995, 56:1113-1120.
59. Kvetnansky R, Pacak K, Fukuhara K, et al: Sympathoadrenal system in stress. Interaction with the hypothalamic-pituitary-adrenocortical system. Ann N Y Acad Sci 1995, 771:131-158.
60. Roozen AW, Tsuma VT, Magnusson U: Effects of short-term restraint stress on plasma concentrations of catecholamines, beta-endorphin, and cortisol in gilts. Am J Vet Res 1995, 56:1225-1227.
61. Parrott RF, Misson BH, de la Riva CF: Differential stressor effects on the concentrations of cortisol, prolactin and catecholamines in the blood of sheep. Res Vet Sci 1994, 56:234-239.