T-cell immunodeficiency following cytotoxic antineoplastic therapy: A review

Stem Cells

Volumn 18, Issue 1, 2000, Pages 10-18

  Mackall, Crystal L ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Immune reconstitution; Immunodeficiency; T cells; Thymus

Indexed keywords

ANTINEOPLASTIC AGENT; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; PURINE NUCLEOSIDE;

CANCER THERAPY; CHEMOPROPHYLAXIS; HUMAN; IMMUNE DEFICIENCY; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOTHERAPY; LYMPHOCYTE DEPLETION; PNEUMOCYSTIS CARINII; PROPHYLAXIS; REVIEW; T LYMPHOCYTE; THYMUS;

PNEUMOCYSTIS CARINII;

EID: 0033969247     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.18-1-10     Document Type: Review

References (69)

1. Michie CA, McLean A, Alcock C et al. The lifespan of human T lymphocytes as defined by CD45 isoforms. Nature 1992;360:264-265.
2. Tough DF, Sprent J. Turnover of naive and memory-phenotype T cells. J Exp Med 1994;179:1127-1135.
3. Freitas AA, Rocha BB. Lymphocyte lifespans: homeostasis, selection and competition. Immunol Today 1993;14:25-29.
4. Pizzo PA, Rubin M, Freifeld A et al. The child with cancer and infection. I. Empiric therapy for fever and neutropenia and preventive strategies. J Pediatr 1991;119:679-694.
5. Lehrnbecher T, Foster C, Vazquez N et al. Therapy-induced alterations in host defense in children receiving therapy for cancer. J Pediatr Hematol Oncol 1997;19:399-417.
6. Hersh EM, Whitecar JP, McCredie KB et al. Chemotherapy, immunocompetence, immunosuppression and prognosis in acute leukemia. N Engl J Med 1971;285:1211-1216.
7. Esber E, DiNicola W, Movassaghi N et al. T and B lymphocytes in leukemia therapy. Am J Hematol 1976;1:211-218.
8. Fuks Z, Strober S, Bobrove AM et al. Long term effects of radiation on T and B lymphocytes in the peripheral blood of patients with Hodgkin's disease. J Clin Invest 1976;58:803a-807a.
9. Magrath IT, Simon RM. Immunosuppression in Burkitt's lymphoma. II. Peripheral blood lymphocyte populations related to clinical status. Int J Cancer 1976;18:399-408.
10. Mackall CL, Fleisher TA, Brown MR et al. Lymphocyte depletion during treatment with intensive chemotherapy for cancer. Blood 1994;84:2221-2228.
11. Hakim FT, Mackall CL. The immune system: effector and target of graft-versus-host disease. In: Ferrara JLM, Deeg HJ, Burakoff SJ, eds. Graft-vs.-Host Disease. New York: Marcel Dekker, Inc., 1996;257-289.
12. Enright H, Haake R, Weisdorf D et al. Cytomegalovirus pneumonia after bone marrow transplantation. Risk factors and response to therapy. Transplantation 1993;55:1339-1346.
13. Miller RA, Daley J, Ghalie R et al. Clonal analysis of T cell deficiencies in autotransplant recipients. Blood 1991;77:1845-1850.
14. Allende M, Pizzo PA, Horowitz M et al. Pulmonary cryptococcosis presenting as metastases in children with sarcomas. Pediatr Infect Dis J 1993;12:240-243.
15. Pizzo PA, Rubin M, Freifeld A et al. The child with cancer and infection. II. Nonbacterial infections. J Pediatr 1991;119:845-857.
16. Gershwin ME, Goetzl EJ, Steinberg AD. Cyclophosphamide: use in practice. Ann Intern Med 1974;80:531-540.
17. Fauci AS, Wolff SM, Johnson JS. Effect of cyclophosphamide upon the immune response in Wegener's Granulomatosis. N Engl J Med 1971;285:1493-1496.
18. Browne MJ, Hubbard SM, Longo DL et al. Excess prevalence of Pneumocystis carinii pneumonia in patients treated for lymphoma with combination chemotherapy. Ann Intern Med 1986;104:338-344.
19. Masur H, Ognibene FP, Yarchoan R et al. CD4 counts as predictors of opportunistic pneumonias in human immuno-deficiency virus infection. Ann Intern Med 1989;111:223-231.
20. Kraut EH, Neff JC, Bouroncle BA et al. Immunosuppressive effects of pentostatin. J Clin Oncol 1990;8:848-855.
21. Urba WJ, Baseler MW, Kopp WC et al. Deoxycoformycin-induced immunosuppression in patients with hairy cell leukemia. Blood 1989;73:38-46.
22. Schilling PJ, Vadhan-Raj S. Concurrent cytomegalovirus and Pneumocystis pneumonia after fludarabine therapy for chronic lymphocytic leukemia. N Engl J Med 1990;323:833-834.
23. Boldt DH, Von Hoff DD, Kuhn JG et al. Effects on human peripheral lymphocytes of in vivo administration of 9-b-D-Arabinofuranosyl-2-fluoroadenine-5′-monophosphate (NSC 312887), a new purine antimetabolite. Cancer Res 1984;44:4661-4666.
24. Dighiero G. Adverse and beneficial immunological effects of purine nucleoside analogues. Hematol Cell Ther 1996;38(suppl 2):S075-S081.
25. Cheson BD. Perspectives on purine analogues. Hematol Cell Ther 1996;38(suppl2):S109-S116.
26. Cheson BD. Infectious and immunosuppressive complications of purine analog therapy. J Clin Oncol 1995;13:2431-2448.
27. Sepkowitz KA, Brown AE, Telzak EE et al. Pneumocystis carinii pneumonia among patients without AIDS at a cancer hospital. JAMA 1992;267:832-837.
28. Henson JW, Jalaj JK, Walker RW et al. Pneumocystis carinii pneumonia in patients with primary brain tumors. Arch Neurol 1991;48:406-409.
29. Slater JM, Ngo E, Lau BHS. Effect of therapeutic irradiation on the immune responses. Radiology 1976;126:313-320.
30. Reckzeh B, Merte H, Pfluger KH et al. Severe lymphocytopenia and interstitial pneumonia in patients treated with paclitaxel and simultaneous radiotherapy for non-small-cell lung cancer. J Clin Oncol 1996;14:1071-1076.
31. Alanko S, Pelliniemi TT, Salmi TT. Recovery of blood B-lymphocytes and serum immunoglobulins after chemotherapy for childhood acute lymphoblastic leukemia. Cancer 1992;69:1481-1486.
32. Sarin A, Wu ML, Henkart P. Different interleukin-1β converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli. J Exp Med 1996;184:2445-2450.
33. Komada Y, Zhang SL, Zhou YW et al. Cellular immunosuppression in children with acute lymphoblastic leukemia: effect of consolidation chemotherapy. Cancer Immunol Immunother 1992;35:271-276.
34. Hakim FT, Cepeda R, Kaimei S et al. Constraints on CD4 recovery post chemotherapy in adults: thymic insufficiency and apoptotic decline of expanded peripheral CD4 cells. Blood 1997;90:3789-3798.
35. Mackall CL, Hakim FT, Gress RE. T-cell regeneration: all repertoires are not created equal. Immunol Today 1997;18:245-251.
36. Ageitos AG, Vamey ML, Bierman PJ et al. Comparison of monocyte-dependent T cell inhibitory activity in GM-CSF vs G-CSF mobilized PSC products. Bone Marrow Transplant 1999;23:63-69.
37. Ino K, Singh RK, Talmadge JE. Monocytes from mobilized stem cells inhibit T cell function. J Leukoc Biol 1997;61:583-591.
38. + T cell regenerative pathways result in prolonged T cell subset imbalance after intensive chemotherapy. Blood 1997;89:3700-3707.
39. Small TN, Keever CA, Weiner-Fedus S et al. B cell differentiation following autologous, conventional or T cell depleted bone marrow transplantation: a recapitulation of normal B cell ontogeny. Blood 1990;76:1647-1656.
40. Storek J, Saxon A. Reconstitution of B cell immunity following bone marrow transplantation. Bone Marrow Transplant 1992;9:395-408.
41. Benoist C, Mathis D. T-Lymphocyte Differentiation and Biology. Philadelphia: Lippincott-Raven, 1999;367-409.
42. Douek DC, McFarland RD, Keiser PH et al. Changes in thymic function with age and during the treatment of HIV infection. Nature 1998;396:690-695.
43. Roederer M, DeRosa SC, Watanabe N et al. Dynamics of fine T-cell subsets during HIV disease and after thymic ablation by mediastinal irradiation. Semin Immunol 1997;9:389-396.
44. Mackall CL, Granger L, Sheard MA et al. T cell regeneration after bone marrow transplantation: differential CD45 isoform expression on thymic-derived versus thymic-independent progeny. Blood 1993;82:2585-2594.
45. Mackall CL, Bare CV, Titus JA et al. Thymic-independent T cell regeneration occurs via antigen driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing. J Immunol 1996;156:4609-4616.
46. + T lymphocyte regeneration after intensive chemotherapy. N Engl J Med 1995;332:143-149.
47. George AJ, Ritter MA. Thymic involution with ageing: obsolescence or good housekeeping? [see comments]. Immunol Today 1996;17:267-272.
48. Weinberg K, Annett G, Kashyap A et al. The effect of thymic function on immunocompetence following bone marrow transplantation. Biol Blood Marrow Transplant 1995;1:18-23.
49. Watanabe N, DeRosa SC, Cmelak A et al. Long-term depletion of naive T cells in patients treated for Hodgkin's disease. Blood 1997;90:3662-3672.
50. + lymphocytes from bone marrow transplanted patients inhibits cell-mediated cytolysis. Blood 1991;77:2237-2241.
51. Lum LG, Orcutt-Thordarson N, Seigneuret MC et al. In vitro regulation of immunoglobulin synthesis by T-cell subpopulations defined by a new human T cell antigen (9.3). Cell Immunol 1982;72:122-129.
52. Damle NK, Engleman EG. Immunoregulatory T cell circuits in man: alloantigen-primed inducer T cells activate alloantigen-specific suppressor T cells in the absence of the initial antigenic stimulus. J Exp Med 1983;158:159-173.
53. - T lymphocytes. Antigenic and functional properties. J Immunol 1993;150:1147-1159.
54. Ohteki T, MacDonald HR. Expression of the CD28 costimulatory molecule on subsets of murine intestinal intraepithelial lymphocytes correlates with lineage and responsiveness. Eur J Immunol 1993;23:1251-1255.
55. Westermann J, Pabst R. Lymphocyte subsets in the blood: a diagnostic window on the lymphoid system? Immunol Today 1990;11:406-409.
56. Michelet C, Arvieux C, Francois C et al. Opportunistic infections occurring during highly active antiretroviral treatment. AIDS 1998;12:1815-1822.
57. American Academy of Pediatrics. Varicella-Zoster Infections. Red Book: Report of the Committee on Infectious Diseases, 1997:573-585.
58. Leitman SF. Use of blood cell irradiation in the prevention of posttransfusion graft-versus-host disease. Transfus Sci 1989;10:219-232.
59. Bustamante CI, Wade JC. Herpes simplex virus infection in the immunocompromised cancer patient. J Clin Oncol 1991;9:1903-1915.
60. Saral R, Ambinder RF, Burns WH et al. Acyclovir prophylaxis against herpes simplex virus infection in patients with leukemia. A randomized, double-blind, placebo-controlled study. Ann Intern Med 1983;99:773-776.
61. Saral R, Burns WH, Laskin OL et al. Acyclovir prophylaxis of herpes-simplex-virus infections. N Engl J Med 1981:305:63-67.
62. Ljungman P, Cordonnier C, de Bock R et al. Immunisations after bone marrow transplantation: results of a European survey and recommendations from the infectious diseases working party of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 1995;15:455-460.
63. Singhal S, Mehta J. Reimmunization after blood or marrow stem cell transplantation [see comments]. Bone Marrow Transplant 1999;23:637-646.
64. Somani J, Larson RA. Reimmunization after allogeneic bone marrow transplantation. Am J Med 1995;98:389-398.
65. Kaplan DH, Shankaran V, Dighe AS et al. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci USA 1998;95:7556-7561.
66. Porter DL, Antin JH. The graft-versus-leukemia effects of allogeneic cell therapy. Annu Rev Med 1999;50:369-386.
67. Bolotin E, Smogorzewska EM, Annett G et al. Enhancement of immune reconstitution by IL-7 after bone marrow transplant (BMT). Blood 1994;3214a.
68. Hughes WT. Pneumocystis carinii pneumonitis in patients with cancer. Infect Med 1996;13:861-862.
69. Mackall CL, Hakim FT, Gress RE. Restoration of T cell homeostasis after T cell depletion. Semin Immunol 1997;9:339-346.